The antipyretic effects of baicalin in lipopolysaccharide-evoked fever in rabbits Fulltext Access 9 Pages 2006
Functional in vitro characterization of CR 3394: A novel voltage dependent N-methyl-d-aspartate (NMDA) receptor antagonist Fulltext Access 9 Pages 2006
Characterisation and differential expression of two very closely related G-protein-coupled receptors, GPR139 and GPR142, in mouse tissue and during mouse development Fulltext Access 9 Pages 2006
BGC20-761, a novel tryptamine analog, enhances memory consolidation and reverses scopolamine-induced memory deficit in social and visuospatial memory tasks through a 5-HT6 receptor-mediated mechanism Fulltext Access 9 Pages 2006
Characterisation of the selective 5-HT1B receptor antagonist SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2â²-methyl-4â²-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): In vivo neurochemic Fulltext Access 9 Pages 2006
D2 dopamine receptor-induced sensitization of adenylyl cyclase type 1 is Gαs independent Fulltext Access 9 Pages 2006
P2X7 receptors exert a permissive role on the activation of release-enhancing presynaptic α7 nicotinic receptors co-existing on rat neocortex glutamatergic terminals Fulltext Access 9 Pages 2006
Attenuation by the 5-HT1A receptor agonist osemozotan of the behavioral effects of single and repeated methamphetamine in mice Fulltext Access 9 Pages 2006
Intrathecal clonidine suppresses zymosan-induced peripheral leukocyte migration in a mouse air pouch model via activation of spinal muscarinic type 2 receptors and sympathoadrenal medullary activity Fulltext Access 9 Pages 2006
Interactions between CB1 cannabinoid and μ opioid receptors mediating inhibition of neurotransmitter release in rat nucleus accumbens core Fulltext Access 9 Pages 2006
Inhibition of tetanically sciatic stimulation-induced LTP of spinal neurons and Fos expression by disrupting glutamate transporter GLT-1 Fulltext Access 9 Pages 2006
Ethanol inhibition of NMDA-induced responses and acute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases Fulltext Access 9 Pages 2006
Discriminative stimulus properties of the selective and highly potent α2-adrenoceptor agonist, S18616, in rats: Mediation by the α2A subtype, and blockade by the atypical antidepressants, mirtazapine and mianserin Fulltext Access 9 Pages 2006
Mefloquine selectively increases asynchronous acetylcholine release from motor nerve terminals Fulltext Access 9 Pages 2006
Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole – LH 21 Fulltext Access 9 Pages 2006
Adolescent and adult responsiveness to the incentive value of cocaine reward in mice: Role of neuronal nitric oxide synthase (nNOS) gene Fulltext Access 9 Pages 2006
Inhibition of jaw opening reflex and single neurons in the trigeminal subnucleus caudalis by activation of striatal D2 dopamine receptors Fulltext Access 9 Pages 2006
25-Hydroxycholesterol has a dual effect on the proliferation of cultured rat astrocytes Fulltext Access 9 Pages 2006
Antiallodynic effect of etidronate, a bisphosphonate, in rats with adjuvant-induced arthritis: Involvement of ATP-sensitive K+ channels Fulltext Access 9 Pages 2006
Near-infrared analysis of protein secondary structure in aqueous solutions and freeze-dried solids Fulltext Access 9 Pages 2006
Tetrazole compounds: The effect of structure and pH on Caco-2 cell permeability Fulltext Access 9 Pages 2006
Transcellular route of diffusion through stratum corneum: Results from finite element models Fulltext Access 9 Pages 2006
Investigation of Solid-State NMR Line Widths of Ibuprofen in Drug Formulations Fulltext Access 9 Pages 2006
Bioadhesive monolayer film for the in vitro transdermal delivery of sumatriptan Fulltext Access 9 Pages 2006
The Effects of Surface Lactone Hydrolysis and Temperature on the Specific and Nonspecific Interactions Between Phenobarbital and Activated Carbon Surfaces Fulltext Access 9 Pages 2006
Anti-trichomonal, biochemical and toxicological activities of methanolic extract and some carbazole alkaloids isolated from the leaves of Murraya koenigii growing in Nigeria Fulltext Access 9 Pages 2006
Screening of antiradical and antioxidant activity of monodesmosides and crude extract from Leontice smirnowii tuber Fulltext Access 9 Pages 2006
Selective inhibition of vascular smooth muscle cell proliferation by coptisine isolated from Coptis rhizoma, one of the crude drugs composing Kampo medicines Unsei-in Fulltext Access 9 Pages 2006
Radical scavenging and anti-inflammatory properties of STW 5 (Iberogast®) and its components Fulltext Access 9 Pages 2006
Effect of isoflavone administration on age-related hepatocyte changes in old ovariectomized femal Wistar rats Fulltext Access 9 Pages 2006
Evaluation of anxiolytic properties of Gotukola – (Centella asiatica) extracts and asiaticoside in rat behavioral models Fulltext Access 9 Pages 2006
Structure prerequisite for antioxidant activity of silybin in different biochemical systems in vitro Fulltext Access 9 Pages 2006
Among the twenty classical l-amino acids, only glutamate directly activates metabotropic glutamate receptors Fulltext Access 9 Pages 2006
Prostaglandin D2 mediates neuronal damage by amyloid-β or prions which activates microglial cells Fulltext Access 9 Pages 2006
Selective inhibition of inducible nitric oxide synthase reduces neurological deficit but not cerebral edema following traumatic brain injury Fulltext Access 9 Pages 2006
Systemic inflammation induces COX-2 mediated prostaglandin D2 biosynthesis in mice spinal cord Fulltext Access 9 Pages 2006
Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones Fulltext Access 9 Pages 2006
Prediction of Tablet Hardness Based on Near Infrared Spectra of Raw Mixed Powders by Chemometrics Fulltext Access 9 Pages 2006
Reversal of neuropathic pain by α-hydroxyphenylamide: A novel sodium channel antagonist Fulltext Access 9 Pages 2006
Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism Fulltext Access 9 Pages 2006
Lysophospholipids elevate [Ca2+]i and trigger exocytosis in bovine chromaffin cells Fulltext Access 9 Pages 2006
Gz proteins are functionally coupled to dopamine D2-like receptors in vivo Fulltext Access 9 Pages 2006
Effect of the selective 5-HT7 receptor antagonist SB 269970 in animal models of anxiety and depression Fulltext Access 9 Pages 2006
A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats Fulltext Access 9 Pages 2006
Ghrelin inhibits inflammatory pain in rats: Involvement of the opioid system Fulltext Access 9 Pages 2006
Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats Fulltext Access 9 Pages 2006
SCH 23390 in the prefrontal cortex enhances the effect of apomorphine on prepulse inhibition of rats Fulltext Access 9 Pages 2006
The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum Fulltext Access 9 Pages 2006
Dehydroepiandrosterone sulfate prevents ischemia-induced impairment of long-term potentiation in rat hippocampal CA1 by up-regulating tyrosine phosphorylation of NMDA receptor Fulltext Access 9 Pages 2006
Evaluation of hydrodynamics in the basket dissolution apparatus using computational fluid dynamics—Dissolution rate implications Fulltext Access 9 Pages 2006
Improving membrane activity of oligonucleotides by cetylpyridinium chloride: An electrochemical study Fulltext Access 9 Pages 2006
Effects of paclitaxel, docetaxel and their combinations on subcutaneous lymphomas in inbred Sprague–Dawley/Cub rats Fulltext Access 9 Pages 2006
LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance Fulltext Access 9 Pages 2006
Single particle friction on blister packaging materials used in dry powder inhalers Fulltext Access 9 Pages 2006
Prodrugs of scutellarin: Ethyl, benzyl and N,N-diethylglycolamide ester synthesis, physicochemical properties, intestinal metabolism and oral bioavailability in the rats Fulltext Access 9 Pages 2006
Solubilization and dissolution of insoluble weak acid, ketoprofen: Effects of pH combined with surfactant Fulltext Access 9 Pages 2006
Regional levels of drug transporters along the human intestinal tract: Co-expression of ABC and SLC transporters and comparison with Caco-2 cells Fulltext Access 9 Pages 2006
Effects of controlled-release on the pharmacokinetics and absorption characteristics of a compound undergoing intestinal efflux in humans Fulltext Access 9 Pages 2006
Analysis of surface properties of cellulose ethers and drug release from their matrix tablets Fulltext Access 9 Pages 2006
Development and evaluation of an in vitro method for prediction of human drug absorption: II. Demonstration of the method suitability Fulltext Access 9 Pages 2006
A strategy for preclinical formulation development using GastroPlus™ as pharmacokinetic simulation tool and a statistical screening design applied to a dog study Fulltext Access 9 Pages 2006
Comparative study of erythritol and lactose monohydrate as carriers for inhalation: Atomic force microscopy and in vitro correlation Fulltext Access 9 Pages 2006
Evaluation of Interethnic Differences in Repinotan Pharmacokinetics by Using Population Approach Fulltext Access 9 Pages 2006
The Novel Formulation Design of Self-emulsifying Drug Delivery Systems (SEDDS) Type O/W Microemulsion III: The Permeation Mechanism of a Poorly Water Soluble Drug Entrapped O/W Microemulsion in Rat Isolated Intestinal Membrane by the Ussing Chamber Method Fulltext Access 9 Pages 2006
Endogenous Uremic Substances are not Involved in the Reduced Hepatic Extraction of Metoprolol in Bilateral Ureter-Ligated Rats† Fulltext Access 9 Pages 2006
Involvement of Human Blood Arylesterases and Liver Microsomal Carboxylesterases in Nafamostat Hydrolysis Fulltext Access 9 Pages 2006
Mutation in an Adaptor Protein PDZKI Affects Transport Activity of Organic Cation Transporter OCTNs and Oligopeptide Transporter PEPT2 Fulltext Access 9 Pages 2006
Thirty Novel Genetic Variations in the SLC29A1 Gene Encoding Human Equilibrative Nucleoside Transporter 1 (hENT1) Fulltext Access 9 Pages 2006
Sequence-based Analysis of the CYP2D6*36-CYP2D6*10 Tandem-type Arrangement, a Major CYP2D6*10 Haplotype in the Japanese Population Fulltext Access 9 Pages 2006
Chenodeoxycholic Acid-mediated Activation of the Farnesoid X Receptor Negatively Regulates Hydroxysteroid Sulfotransferase Fulltext Access 9 Pages 2006
Characterization of Humanized Liver from Chimeric Mice Using Coumarin as a Human CYP2A6 and Mouse CYP2A5 Probe Fulltext Access 9 Pages 2006
Bile Acid Salt Binding with Colesevelam HCl is Not Affected by Suspension in Common Beverages Fulltext Access 9 Pages 2006
Primary Microparticles and Agglomerates of Morphine for Nasal Insufflation Fulltext Access 9 Pages 2006
Thiol exchange: An in vitro assay that predicts the efficacy of novel homocysteine lowering therapies Fulltext Access 9 Pages 2006
Static light scattering and small-angle neutron scattering study on aggregated recombinant gelatin in aqueous solution Fulltext Access 9 Pages 2006
An efficient approach for the rapid assessment of oral rat exposures for new chemical entities in drug discovery Fulltext Access 9 Pages 2006
Release-Controlling Absorption Enhancement of Enterally Administered Ophiopogon Japonicus Polysaccharide by Sodium Caprate in Rats Fulltext Access 9 Pages 2006
Acrylic terpolymer microcapsules for colon-specific drug delivery: effect of molecular weight and solubility of microencapsulated drugs on their release behaviors Fulltext Access 9 Pages 2006
Optimization of cross-linked high amylose starch microspheres containing 5-fluorouracil Fulltext Access 9 Pages 2006
Kinetic validation of the use of carboxydichlorofluorescein as a drug surrogate for MRP5-mediated transport Fulltext Access 9 Pages 2006
Temporal Decline in Sirolimus Elimination Immediately After Pancreatic Islet Transplantation Fulltext Access 9 Pages 2006
Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line Fulltext Access 9 Pages 2006
Relationship between genotype and enzyme activity of glutathione S-transferases M1 and P1 in Chinese Fulltext Access 9 Pages 2006
Limited interaction between tacrolimus and P-glycoprotein in the rat small intestine Fulltext Access 9 Pages 2006
Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: Comparison between human segments and Caco-2 cells Fulltext Access 9 Pages 2006
Neurotrophic factor production in human astrocytoma cells by 2,5,6-tribromogramine via activation of epsilon isoform of protein kinase C Fulltext Access 9 Pages 2006
Physico-chemical lyophilization behavior of mannitol, human serum albumin formulations Fulltext Access 9 Pages 2006
Development of polysaccharide gel-coated pellets for oral administration: 2. Calcium alginate Fulltext Access 9 Pages 2006
Effect of 2,6-di-O-methyl-α-cyclodextrin on hemolysis and morphological change in rabbit's red blood cells Fulltext Access 9 Pages 2006
Inhibition of efflux transporter ABCG2/BCRP does not restore mitoxantrone sensitivity in irinotecan-selected human leukemia CPT-K5 cells: Evidence for multifactorial multidrug resistance Fulltext Access 9 Pages 2006
Designing novel pH-sensitive non-phospholipid vesicle: Characterization and cell interaction Fulltext Access 9 Pages 2006