Development and validation of novel imaging technologies to assist translational studies in atherosclerosis Fulltext Access 10 Pages 2006
Diastereoselective synthesis of enantioenriched homopropargyl amino alcohols from α-dibenzylamino aldehydes and their use as chiral synthons Fulltext Access 10 Pages 2006
Synthesis of 1-C-alkyl-α-d-glucopyranosides by Lewis acid- or Brønsted acid-catalyzed O-glycosidation Fulltext Access 10 Pages 2006
Reaction of ene-bis(phosphinylallenes): [2+2] versus [4+2] cycloaddition Fulltext Access 10 Pages 2006
Construction of divergent anthracene arrays within dendritic frameworks Fulltext Access 10 Pages 2006
Co-catalyzed reductive cyclization of azido and cyano substituted α,β-unsaturated esters with NaBH4: enantioselective synthesis of (R)-baclofen and (R)-rolipram Fulltext Access 10 Pages 2006
Graphene quantum dots enhance anticancer activity of cisplatin via increasing its cellular and nuclear uptake Fulltext Access 10 Pages 2006
Beyond interferon and ribavirin: Antiviral therapies for hepatitis C virus Fulltext Access 10 Pages 2006
Immune response modifiers: Imiquimod and future drugs for modulating the immune response Fulltext Access 10 Pages 2006
Conjugates of methyl 6-aminopenicillanate with biscatechol-hydroxamate chelators: synthesis and siderophoric activity Fulltext Access 10 Pages 2006
Role of pharmacologically active metabolites in drug discovery and development Fulltext Access 10 Pages 2006
Vascular NADPH oxidases as drug targets for novel antioxidant strategies Fulltext Access 10 Pages 2006
R&D technology investments: misguided and expensive or a better way to discover medicines? Fulltext Access 10 Pages 2006
A facile access to spiro furanone skeleton based on Pd(II)-mediated cyclization-carbonylation of propargylic esters Fulltext Access 10 Pages 2006
Synthetic study of tautomycin. Part 2: Synthesis of Ichihara's fragment based on regioselective enzymatic acetylation of complex molecule Fulltext Access 10 Pages 2006
Oxidized isoquinolinoisoindolinone and benzazepinoisoindolinone alkaloids cores by convergent cyclisation processes: Ï-aromatic attack of thionium and oxonium species Fulltext Access 10 Pages 2006
Reaction of quinidine acetate, epiquinidine and its acetate in superacid: formation of gem-difluoro derivatives with or without rearrangement Fulltext Access 10 Pages 2006
Cycloalkano[1â³,2â³:4,5;4â³,3â³:4â²,5â²]bis(pyrrolo[2,3-c]pyrimido[5,4-e]pyridazines): synthesis, structure and mechanism of their formation Fulltext Access 10 Pages 2006
Exploring unusual antioxidant activity in a benzoic acid derivative: a proposed mechanism for citrinin Fulltext Access 10 Pages 2006
Abnormal Beckmann rearrangement of steroidal α-chlorocyclobutanone oximes: the fragmentation-substitution reaction Fulltext Access 10 Pages 2006
Supramolecular nanostructured assemblies of different types of porphyrins with fullerene using TiO2 nanoparticles for light energy conversion Fulltext Access 10 Pages 2006
Enantioselective tandem Michael reaction to nitroalkene catalyzed by bifunctional thiourea: total synthesis of (â)-epibatidine Fulltext Access 10 Pages 2006
Influence of electronic and steric factors on 2,3-dihydroimidazo[1,2-a]pyridine-based enantioselective acylation catalysts Fulltext Access 10 Pages 2006
Total synthesis of the epoxyquinol dimer (+)-panepophenanthrin: application of a diastereospecific biomimetic Diels-Alder dimerisation Fulltext Access 10 Pages 2006
Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents Fulltext Access 10 Pages 2006
Molecular recognition of viologen by zinc porphyrinic receptors with diarylurea sidearms. Toward construction of a supramolecular electron transfer system Fulltext Access 10 Pages 2006
Structure elucidation of dicarboxylate complex of SnIV porphyrin with a ring current effect model Fulltext Access 10 Pages 2006
A coordinatively unsaturated ruthenium methoxide as a highly effective catalyst for the halogen atom-transfer radical cyclization of N-allyl dichloroacetamides and related reactions Fulltext Access 10 Pages 2006
The cyclopropyl effect on the regioselectivity of coupling reactions involving the lithiation of 1-cyclopropyl-2-arylacetylenes Fulltext Access 10 Pages 2006
Asymmetric aziridine synthesis by aza-Darzens reaction of N-diphenylphosphinylimines with chiral enolates. Part 2: Inversion of diastereoselectivity Fulltext Access 10 Pages 2006
Homohelicity induction of propylene-linked zinc bilinone dimers by complexation with chiral amine and α-amino esters. Preorganization of structurally coupled homohelical subunits Fulltext Access 10 Pages 2006
Peracid dependent stereoselectivity and functional group contribution to the stereocontrol of epoxidation of (E)-alkene dipeptide isosteres Fulltext Access 10 Pages 2006
Synthesis of cyclic dienamide using ruthenium-catalyzed ring-closing metathesis of ene-ynamide Fulltext Access 10 Pages 2006
Organolithiums by reductive lithiation: the catalytic aromatic method versus the use of preformed aromatic radical-anions. Naphthalene can behave as a catalyst or an inhibitor Fulltext Access 10 Pages 2006
A new method for generation of non-stabilized α-amino-substituted carbanions by the reaction of magnesium carbenoids with N-lithio arylamines: their reactivity and a new synthesis of α-amino acid derivatives Fulltext Access 10 Pages 2006
Bringing nanomedicines to market: regulatory challenges, opportunities, and uncertainties Fulltext Access 10 Pages 2006
Characterization of Moenomycin Antibiotic Complex by Multistage MALDI-IT/RTOF-MS and ESI-IT-MS Fulltext Access 10 Pages 2006
Sequence Analysis of Alginate-Derived Oligosaccharides by Negative-Ion Electrospray Tandem Mass Spectrometry Fulltext Access 10 Pages 2006
Evaluation of Binding Affinity of Protein–Mutant DNA Complexes in Solution by Laser Spray Mass Spectrometry Fulltext Access 10 Pages 2006
Long-Lived Electron Capture Dissociation Product Ions Experience Radical Migration via Hydrogen Abstraction Fulltext Access 10 Pages 2006
Identification of Mammalian Cell Lines Using MALDI-TOF and LC-ESI-MS/MS Mass Spectrometry Fulltext Access 10 Pages 2006
Electrospray Mass Spectrometry of NeuAc Oligomers Associated with the C Fragment of the Tetanus Toxin Fulltext Access 10 Pages 2006
Peptide Ozonolysis: Product Structures and Relative Reactivities for Oxidation of Tyrosine and Histidine Residues Fulltext Access 10 Pages 2006
A Deconvolution Method for the Separation of Specific Versus Nonspecific Interactions in Noncovalent Protein-Ligand Complexes Analyzed by ESI-FT-ICR Mass Spectrometry Fulltext Access 10 Pages 2006
Thermal Decomposition of Multiply Charged T-Rich Oligonucleotide Anions in the Gas Phase. Influence of Internal Solvation on the Arrhenius Parameters for Neutral Base Loss Fulltext Access 10 Pages 2006
The Antigenic Determinants on HIV p24 for CD4+ T Cell Inhibiting Antibodies as Determined by Limited Proteolysis, Chemical Modification, and Mass Spectrometry Fulltext Access 10 Pages 2006
Protein Identification via Surface-Induced Dissociation in an FT-ICR Mass Spectrometer and a Patchwork Sequencing Approach Fulltext Access 10 Pages 2006
Fabrication of biofunctional nanomaterials via Escherichia coli OmpF protein air/water interface insertion/integration with copolymeric amphiphiles Fulltext Access 10 Pages 2006
Adsorption and diffusion of benzene in the nanoporous catalysts FAU, ZSM-5 and MCM-22: A molecular dynamics study Fulltext Access 10 Pages 2006
Linear interaction energy models for β-secretase (BACE) inhibitors: Role of van der Waals, electrostatic, and continuum-solvation terms Fulltext Access 10 Pages 2006
Adsorption equilibria of hydrocarbons in the structure of the reforming catalyst: Molecular modeling Fulltext Access 10 Pages 2006
Molecular dynamics characterization of n-octyl-β-d-glucopyranoside micelle structure in aqueous solution Fulltext Access 10 Pages 2006
Multiple target screening method for robust and accurate in silico ligand screening Fulltext Access 10 Pages 2006
A neural networks-based drug discovery approach and its application for designing aldose reductase inhibitors Fulltext Access 10 Pages 2006
Binding mode analysis of the NADH cofactor in nitric oxide reductase: A theoretical study Fulltext Access 10 Pages 2006
Enantioselective addition of diethylzinc to aldehydes catalyzed by monosubstituted [2.2]paracyclophane-based N,O-ligands: remarkable cooperative effects of planar and central chiralities Fulltext Access 10 Pages 2006
Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives Fulltext Access 10 Pages 2006
A platform for designing HIV integrase inhibitors. Part 2: A two-metal binding model as a potential mechanism of HIV integrase inhibitors Fulltext Access 10 Pages 2006
Design, synthesis, and evaluation of a novel series of α-substituted phenylpropanoic acid derivatives as human peroxisome proliferator-activated receptor (PPAR) α/δ dual agonists for the treatment of metabolic syndrome Fulltext Access 10 Pages 2006
Synthesis and evaluation of general mechanism-based inhibitors of sulfatases based on (difluoro)methyl phenyl sulfate and cyclic phenyl sulfamate motifs Fulltext Access 10 Pages 2006
Synthesis of some substituted pyrazinopyridoindoles and 3D QSAR studies along with related compounds: Piperazines, piperidines, pyrazinoisoquinolines, and diphenhydramine, and its semi-rigid analogs as antihistamines (H1) Fulltext Access 10 Pages 2006
Stereoselective synthesis of enantiopure γ-aminoalcohols by reduction of chiral β-enaminoketones Fulltext Access 10 Pages 2006
Carboxymethylated cyclodextrin derivatives as chiral NMR discriminating agents Fulltext Access 10 Pages 2006
Studies on epoxidation of enantiomerically pure 2,3-dideoxy hex-2-enitols: a convenient access to highly functionalized enantiomerically pure tetrahydrofuran derivatives Fulltext Access 10 Pages 2006
Chiral pyridinium-based ionic liquids containing the (1R,2S,5R)-(−)-menthyl group Fulltext Access 10 Pages 2006
First chiral synthesis of the N-terminal amino acid congener of nikkomycin Z based on lipase-catalyzed enantioselective acetylation of a primary alcohol possessing two stereogenic centers Fulltext Access 10 Pages 2006
CoMFA methodology in structure-activity analysis of hexahydro- and octahydropyrido[1,2-c]pyrimidine derivatives based on affinity towards 5-HT1A, 5-HT2A and α1-adrenergic receptors Fulltext Access 10 Pages 2006
O-Methylatrolactic acid as a new reagent for determination of the enantiomeric purity and absolute configuration of chiral alcohols and amines Fulltext Access 10 Pages 2006
Synthesis of (1S,4R)-4-isopropyl-1-methyl-2-cyclohexen-1-ol, the aggregation pheromone of the ambrosia beetle Platypus quercivorus, its racemate, (1R,4R)- and (1S,4S)-isomers Fulltext Access 10 Pages 2006
Chemoenzymatic synthesis of diastereomeric ethyl γ-benzyl paraconates and determination of the absolute configurations of their acids Fulltext Access 10 Pages 2006
Synthesis of enantiomerically pure (+)- and (−)-protected 5-aminomethyl-1,3-oxazolidin-2-one derivatives from allylamine and carbon dioxide Fulltext Access 10 Pages 2006
Synthesis of new enantiopure proton-ionizable crown ethers containing a dialkylhydrogenphosphate moiety Fulltext Access 10 Pages 2006
Circular dichroism studies on absolute configuration assignment of peptidomimetics with a terminal chiral 3-arylpropionic acid unit Fulltext Access 10 Pages 2006
Algorithms for Automatic Interpretation of High Resolution Mass Spectra Fulltext Access 10 Pages 2006
Characterization of Cardiolipin from Escherichia coli by Electrospray Ionization with Multiple Stage Quadrupole Ion-Trap Mass Spectrometric Analysis of [M − 2H + Na]− ions Fulltext Access 10 Pages 2006
An Impulse-Driven Liquid-Droplet Deposition Interface for Combining LC with MALDI MS and MS/MS Fulltext Access 10 Pages 2006