Effects of a novel glutamate transporter blocker, (2S, 3S)-3-{3-[4-(trifluoromethyl)benzoylamino]benzyloxy}aspartate (TFB-TBOA), on activities of hippocampal neurons Fulltext Access 13 Pages 2005
Establishment of robust functional assays for the characterization of neuropeptide Y (NPY) receptors: identification of 3-(5-benzoyl-thiazol-2-ylamino)-benzonitrile as selective NPY type 5 receptor antagonist Fulltext Access 13 Pages 2005
Dopamine inhibits cell growth and cell cycle by blocking ribonucleotide reductase Fulltext Access 13 Pages 2005
Neurosteroid paradoxical enhancement of paired-pulse inhibition through paired-pulse facilitation of inhibitory circuits in dentate granule cells Fulltext Access 13 Pages 2005
Binding and functional properties of the novel somatostatin analogue KE 108 at native mouse somatostatin receptors Fulltext Access 13 Pages 2005
Long-term potentiation persists in an occult state following mGluR-dependent depotentiation Fulltext Access 13 Pages 2005
Peripheral, but not central effects of cannabidiol derivatives: Mediation by CB1 and unidentified receptors Fulltext Access 13 Pages 2005
β-Carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway Fulltext Access 13 Pages 2005
Interaction of corticosterone and nicotine in regulation of prepulse inhibition in mice Fulltext Access 13 Pages 2005
Virus-encoded chemokine receptors - putative novel antiviral drug targets Fulltext Access 13 Pages 2005
Biodistribution of 68Ga-labelled phosphodiester, phosphorothioate, and 2â²-O-methyl phosphodiester oligonucleotides in normal rats Fulltext Access 13 Pages 2005
Antiabsence effects of carbenoxolone in two genetic animal models of absence epilepsy (WAG/Rij rats and lh/lh mice) Fulltext Access 13 Pages 2005
Tissue distribution, pharmacokinetics and identification of roscovitine metabolites in rat Fulltext Access 13 Pages 2005
Multicomponent complex formation between vinpocetine, cyclodextrins, tartaric acid and water-soluble polymers monitored by NMR and solubility studies Fulltext Access 13 Pages 2005
Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing Fulltext Access 13 Pages 2005
Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus Fulltext Access 13 Pages 2005
The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors Fulltext Access 13 Pages 2005
Coupling of human nicotinic acetylcholine receptors α7 to calcium channels in GH3 cells Fulltext Access 13 Pages 2005
Transmembrane domains 1 and 3 of the glycine transporter GLYT1 contain structural determinants of N[3-(4â²-fluorophenyl)-3-(4â²-phenylphenoxy)-propyl]sarcosine specificity Fulltext Access 13 Pages 2005
Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter Fulltext Access 13 Pages 2005
Expression studies of naturally occurring human dopamine transporter variants identifies a novel state of transporter inactivation associated with Val382Ala Fulltext Access 13 Pages 2005
Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder Fulltext Access 13 Pages 2005
Dissection of peripheral and central endogenous opioid modulation of systemic interleukin-1β responses using c-fos expression in the rat brain Fulltext Access 13 Pages 2005
M3-like muscarinic receptors mediate Ca2+ influx in rat mesencephalic GABAergic neurones through a protein kinase C-dependent mechanism Fulltext Access 14 Pages 2005
PKC modulation of GABAA receptor endocytosis and function is inhibited by mutation of a dileucine motif within the receptor β2 subunit Fulltext Access 14 Pages 2005
Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP Fulltext Access 14 Pages 2005
Differential ion current activation by human 5-HT1A receptors in Xenopus oocytes: Evidence for agonist-directed trafficking of receptor signalling Fulltext Access 14 Pages 2005
Structural characterization of cardiolipin by tandem quadrupole and multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization Fulltext Access 14 Pages 2005
Biphenyls labeled with technetium 99m for imaging β-amyloid plaques in the brain Fulltext Access 14 Pages 2005
Carbon-11 HOMADAM: A novel PET radiotracer for imaging serotonin transporters Fulltext Access 14 Pages 2005
Keynote review: The auditory system, hearing loss and potential targets for drug development Fulltext Access 14 Pages 2005
Potential for enlarging DNA memory: the validity of experimental operations of scaled-up nested primer molecular memory Fulltext Access 14 Pages 2005
Effects of patch temperature on spontaneous action potential train due to channel fluctuations: Coherence resonance Fulltext Access 14 Pages 2005
Studies of intestinal drug transport using an in silico epithelio-mimetic device Fulltext Access 14 Pages 2005
Duty Cycle and Modulation Efficiency of Two-Channel Hadamard Transform Time-of-Flight Mass Spectrometry Fulltext Access 14 Pages 2005
Total structure characterization of unsaturated acidic phospholipids provided by vicinal di-hydroxylation of fatty acid double bonds and negative electrospray ionization mass spectrometry Fulltext Access 14 Pages 2005
Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease Fulltext Access 14 Pages 2005
Influence of the Labeling Group on Ionization and Fragmentation of Carbohydrates in Mass Spectrometry Fulltext Access 14 Pages 2005
The preparation by extrusion/spheronization and the properties of pellets containing drugs, microcrystalline cellulose and glyceryl monostearate Fulltext Access 14 Pages 2005
EUFEPS conference on Drug Transporters at Copenhagen: Integrative approaches in ADME research Fulltext Access 14 Pages 2005
Absorption properties and P-glycoprotein activity of modified Caco-2 cell lines Fulltext Access 14 Pages 2005
Adaptogenic activity of glyco-peptido-lipid fraction from the alcoholic extract of Trichopus zeylanicus Gaerten (part II) Fulltext Access 14 Pages 2005
Protective effects of ginseng saponins on 3-nitropropionic acid-induced striatal degeneration in rats Fulltext Access 14 Pages 2005
A comparison of neurokinin 1 receptor knock-out (NK1â/â) and wildtype mice: exploratory behaviour and extracellular noradrenaline concentration in the cerebral cortex of anaesthetised subjects Fulltext Access 14 Pages 2005
Presynaptic α7 and non-α7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro Fulltext Access 14 Pages 2005
Dialkylzinc mediated radical additions to chiral N-enoyloxazolidinones in the presence of benzaldehyde. Mechanistic investigation, structural characterization of the resulting γ-lactones Fulltext Access 14 Pages 2005
Regioselective synthesis of 1,7-dioxaspiro[4.4]nonanes from a trimethylenemethane dianion synthon Fulltext Access 14 Pages 2005
An efficient entry to pyrrolo[1,2-b]isoquinolines and related systems through Parham cyclisation Fulltext Access 14 Pages 2005
The preparation and resolution of 2-(2-pyridyl)- and 2-(2-pyrazinyl)-Quinazolinap and their application in palladium-catalysed allylic substitution Fulltext Access 14 Pages 2005
Novel cytotoxic kaurane-type diterpenoids from the New Zealand Liverwort Jungermannia species Fulltext Access 14 Pages 2005
Spectrokinetic studies on new bi-photochromic molecules containing two naphthopyran entities Fulltext Access 14 Pages 2005
Porphyrins with exocyclic rings. Part 19: Efficient syntheses of phenanthrolinoporphyrins Fulltext Access 14 Pages 2005
Palladium mediated spiroketal synthesis: application to pheromone synthesis Fulltext Access 14 Pages 2005
The first sorbicillinoid alkaloids, the antileukemic sorbicillactones A and B, from a sponge-derived Penicillium chrysogenum strain Fulltext Access 14 Pages 2005
Asymmetric synthesis of cytotoxic sponge metabolites R-strongylodiols A and B and an analogue Fulltext Access 14 Pages 2005
Stereocontrol in cycloadditions of (1Z,4R*,5R*)-1-arylmethylidene-4-benzoylamino-5-phenylpyrazolidin-3-on-1-azomethine imines Fulltext Access 14 Pages 2005
Highly regio- and stereo-selective carbometallation reaction of fluorine-containing internal acetylenes with organocopper reagents Fulltext Access 14 Pages 2005
Reactions of guaiazulene with 2-furaldehyde, thiophene-2-carbaldehyde and pyrrole-2-carbaldehyde in methanol in the presence of hexafluorophosphoric acid: comparative studies on molecular structures and spectroscopic, chemical and electrochemical properti Fulltext Access 14 Pages 2005
Synthetic studies related to diketopyrrolopyrrole (DPP) pigments. Part 3: Syntheses of tri- and tetra-aryl DPPs Fulltext Access 14 Pages 2005
Electron transfer-initiated asymmetric photocyclization of chiral auxiliary-substituted N-acyl-α-dehydro(1-naphthyl)alaninamides to the corresponding 3,4-dihydrobenzo[f]quinolinone derivatives Fulltext Access 14 Pages 2005
A new method for synthesis of α,α-disubstituted carbonyl compounds from carbonyl compounds with one-carbon homologation through β-oxido carbenoid rearrangement as the key reaction Fulltext Access 14 Pages 2005
Non-biaryl atropisomers derived from carbohydrates. Part 3: Rotational isomerism of sterically hindered heteroaryl imidazolidine-2-ones and 2-thiones Fulltext Access 14 Pages 2005
Preorganization in the Nazarov cyclization: the role of adjacent coordination sites in the highly Lewis acidic catalyst [IrMe(CO)(dppe)(DIB)](BAr4f)2 Fulltext Access 14 Pages 2005
Solid state characterization of mometasone furoate anhydrous and monohydrate forms Fulltext Access 14 Pages 2005
Population balance modeling of aggregation kinetics of recombinant human interleukin-1 receptor antagonist Fulltext Access 14 Pages 2005
Release of Poorly Soluble Drugs from HPMC Tablets Studied by FTIR Imaging and Flow-Through Dissolution Tests Fulltext Access 14 Pages 2005
Structure/Function Relationships of Polyamidoamine/DNA Dendrimers as Gene Delivery Vehicles Fulltext Access 14 Pages 2005
Alterations in GABAA receptor occupancy occur during the postnatal development of rat Purkinje cell but not granule cell synapses Fulltext Access 14 Pages 2005
Short-term steroid treatment increases δ GABAA receptor subunit expression in rat CA1 hippocampus: Pharmacological and behavioral effects Fulltext Access 14 Pages 2005
Neuro-modulation, aminergic neuro-disinhibition and neuro-degeneration. Fulltext Access 14 Pages 2005
Non-termination of sickness behavior as precipitating factor for mental disorders Fulltext Access 14 Pages 2005
Influence of Asymmetric Donor-Receiver ion Concentration Upon Transscleral Iontophoretic Transport Fulltext Access 14 Pages 2005
Prediction of Contact Angle for Pharmaceutical Solids from Their Molecular Structure Fulltext Access 14 Pages 2005
Immobilization of Ibuprofen and Copper-Ibuprofen Drugs on Layered Double Hydroxides Fulltext Access 14 Pages 2005
Pharmaceutical Development of a Lyophilised Dosage Form for the Investigational Anticancer Agent Imexon Using Dimethyl Sulfoxide as Solubilising and Stabilising Agent Fulltext Access 14 Pages 2005
Stabilization of human papillomavirus virus-like particles by non-ionic surfactants Fulltext Access 14 Pages 2005
Cationic cage-like complexes formed by DC-cholesterol, Quil-A, and phospholipid Fulltext Access 14 Pages 2005
Effects of Tween 20® and Tween 80® on the Stability of Albutropin During Agitation Fulltext Access 14 Pages 2005
Solid-State Stability and Characterization of Hot-Melt Extruded Poly(ethylene oxide) Films Fulltext Access 14 Pages 2005
Multidisciplinary Investigation of Atypical Inclusion Complexes of β-Cyclodextrin and a Phospholipase-A2 Inhibitor Fulltext Access 14 Pages 2005
Effect of the Covalent Modification with Poly(ethylene glycol) on α-Chymotrypsin Stability upon Encapsulation in Poly(lactic-co-glycolic) Microspheres Fulltext Access 14 Pages 2005
Measurement of Process-Dependent Material Properties of Pharmaceutical Solids by Nanoindentation Fulltext Access 14 Pages 2005
Uniform Encapsulation of Stable Protein Nanoparticles Produced by Spray Freezing for the Reduction of Burst Release Fulltext Access 14 Pages 2005
Pharmacodynamic interactions between recombinant mouse interleukinâ10 and prednisolone using a mouse endotoxemia model Fulltext Access 14 Pages 2005
Rapid pKa estimation using vacuumâassisted multiplexed capillary electrophoresis (VAMCE) with ultraviolet detection Fulltext Access 14 Pages 2005
Downâregulation of aryl hydrocarbon receptor-regulated genes by tumor necrosis factorâα and lipopolysaccharide in murine hepatoma hepa 1c1c7 cells Fulltext Access 14 Pages 2005
Intramolecular 1,3-dipolar nitrone and nitrile oxide cycloaddition of 2- and 4-O-allyl and propargyl glucose derivatives: a versatile approach to chiral cyclic ether fused isoxazolidines, isoxazolines and isoxazoles Fulltext Access 14 Pages 2005
Michael addition of chiral formaldehyde N,N-dialkylhydrazones to activated cyclic alkenes Fulltext Access 14 Pages 2005