Synthesis of external β-turn templates by reaction of protected dehydroamino acids with cyclic enaminoesters Fulltext Access 13 Pages 2005
Synthesis, molecular structure, and in vitro antitumor activity of new 4-chloro-2-mercaptobenzenesulfonamide derivatives Fulltext Access 13 Pages 2005
Synthesis, dopamine D2 receptor binding studies and docking analysis of 5-[3-(4-arylpiperazin-1-yl)propyl]-1H-benzimidazole, 5-[2-(4-arylpiperazin-1-yl)ethoxy]-1H-benzimidazole and their analogs Fulltext Access 13 Pages 2005
Aromatic-aromatic and proline-aromatic interactions in endomorphin-1 and endomorphin-2 Fulltext Access 13 Pages 2005
Molecular design, synthesis, and hypoglycemic and hypolipidemic activities of novel pyrimidine derivatives having thiazolidinedione Fulltext Access 13 Pages 2005
Synthesis and transformations of alkyl N-(1-cyclohex-3-enyl)carbamates prepared from cyclohex-3-ene carboxylic acid via Curtius rearrangement Fulltext Access 13 Pages 2005
Synthesis and conformational analysis of 18-membered Aib-containing cyclohexapeptides Fulltext Access 13 Pages 2005
Novel triazinium-imidothioate zwitterions: intermediates in the reaction of [1,3,4]thiadiazolo[2,3-d][1,2,4]triazolo[1,5-a][1,3,5]triazinium cations with amines Fulltext Access 13 Pages 2005
A free radical cyclization approach to indolo-benzodiazocine derivatives Fulltext Access 13 Pages 2005
RuO4-catalyzed oxidative polycyclization of squalene. Determination of the configuration of the penta-tetrahydrofuranyl diol product Fulltext Access 13 Pages 2005
MDMA ('Ecstasy') and methamphetamine combined: Order of administration influences hyperthermic and long-term adverse effects in female rats Fulltext Access 13 Pages 2005
The dissipation of neuropathic pain paradoxically involves the presence of tumor necrosis factor-α (TNF) Fulltext Access 13 Pages 2005
Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen Fulltext Access 13 Pages 2005
mGluR5, but not mGluR1, antagonist modifies MK-801-induced locomotor activity and deficit of prepulse inhibition Fulltext Access 13 Pages 2005
1-Ethyl-2-benzimidazolinone (EBIO) suppresses epileptiform activity in in vitro hippocampus Fulltext Access 13 Pages 2005
Effects of sucrose and mannitol on asparagine deamidation rates of model peptides in solution and in the solid state Fulltext Access 13 Pages 2005
Kinetics and Mechanism of the Reaction of Cysteine and Hydrogen Peroxide in Aqueous Solution Fulltext Access 13 Pages 2005
Glass Transition-Related Changes in Molecular Mobility below Glass Transition Temperature of Freeze-Dried Formulations, as Measured by Dielectric Spectroscopy and Solid State Nuclear Magnetic Resonance Fulltext Access 13 Pages 2005
Biosensor Analysis of the Interaction between Drug Compounds and Liposomes of Different Properties; a Two-Dimensional Characterization Tool for Estimation of Membrane Absorption Fulltext Access 13 Pages 2005
The Novel Formulation Design of Self-emulsifying Drug Delivery Systems (SEDDS) Type O/W Microemulsion I: Enhancing Effects on Oral Bioavailability of Poorly Water Soluble Compounds in Rats and Beagle Dogs Fulltext Access 13 Pages 2005
Synthesis and biological evaluation of trans-3-phenyl-1-indanamines as potential norepinephrine transporter imaging agents Fulltext Access 13 Pages 2005
Protein structure similarity clustering and natural product structure as guiding principles in drug discovery Fulltext Access 13 Pages 2005
Keynote review: Intestinal Peyer's patch M cells and oral vaccine targeting Fulltext Access 13 Pages 2005
Keynote review: Mammalian carboxylesterases: From drug targets to protein therapeutics Fulltext Access 13 Pages 2005
Keynote review: In vitro safety pharmacology profiling: an essential tool for successful drug development Fulltext Access 13 Pages 2005
A mathematical model of combination therapy using the EGFR signaling network Fulltext Access 13 Pages 2005
Role of two toxin-producing plankton and their effect on phytoplankton-zooplankton system - a mathematical study supported by experimental findings Fulltext Access 13 Pages 2005
Modeling the effect of acylated homoserine lactone antagonists in Pseudomonas aeruginosa Fulltext Access 13 Pages 2005
A principle of fractal-stochastic dualism and Gompertzian dynamics of growth and self-organization Fulltext Access 13 Pages 2005
Pharmacokinetic-Pharmacodynamic Analysis of Antipsychotics-induced Extrapyramidal Symptoms based on Receptor Occupancy Theory Incorporating Endogenous Dopamine Release Fulltext Access 13 Pages 2005
Phenomenological and molecular-level Petri net modeling and simulation of long-term potentiation Fulltext Access 13 Pages 2005
Binding of a Diphosphorylated-ITAM Peptide to Spleen Tyrosine Kinase (Syk) Induces Distal Conformational Changes: A Hydrogen Exchange Mass Spectrometry Study Fulltext Access 13 Pages 2005
Peptide Mass Mapping of Acetylated Isoforms of Histone H4 from Mouse Lymphosarcoma Cells Treated with Histone Deacetylase (HDACs) Inhibitors Fulltext Access 13 Pages 2005
Mass Spectrometric Studies of the Gas Phase Retro-Michael Type Fragmentation Reactions of 2-Hydroxybenzyl-N-Pyrimidinylamine Derivatives Fulltext Access 13 Pages 2005
Experimental and Theoretical Investigations of the Loss of Amino Acid Side Chains in Electron Capture Dissociation of Model Peptides Fulltext Access 13 Pages 2005
Studies on Phosphatidylserine by Tandem Quadrupole and Multiple Stage Quadrupole Ion-Trap Mass Spectrometry with Electrospray Ionization: Structural Characterization and the Fragmentation Processes Fulltext Access 13 Pages 2005
Direct Correlation of the Crystal Structure of Proteins with the Maximum Positive and Negative Charge States of Gaseous Protein Ions Produced by Electrospray Ionization Fulltext Access 13 Pages 2005
Investigation of the Initial Fragmentation of Oligodeoxynucleotides in a Quadrupole Ion Trap: Charge Level-Related Base Loss Fulltext Access 13 Pages 2005
A Novel Mass Spectrometric Method to Distinguish Isobaric Monosaccharides that are Phosphorylated or Sulfated Using Ion-Pairing Reagents Fulltext Access 13 Pages 2005
Unsupervised Spike Sorting of extracellular electrophysiological recording in subthalamic nucleus of Parkinsonian patients Fulltext Access 13 Pages 2005
Four-component Pd-catalysed cascade/ring closing metathesis. Synthesis of heterocyclic enones Fulltext Access 13 Pages 2005
Stereoselective synthesis of (Z)-fluoroalkenes directed to peptide isosteres: copper mediated reaction of trialkylaluminum with 4,4-difluoro-5-hydroxyallylic alcohol derivatives Fulltext Access 13 Pages 2005
Synthesis of fused or not β-lactam-biaryl hybrids by free radical aryl-aryl coupling of 2-azetidinone-tethered haloarenes Fulltext Access 13 Pages 2005
Oxidation of sulfides to sulfoxides. Part 2: Oxidation by hydrogen peroxide Fulltext Access 13 Pages 2005
Lipophilic peptide nucleic acids containing a 1,3-diyne function: synthesis, characterization and production of derived polydiacetylene liposomes Fulltext Access 13 Pages 2005
Synthesis of some oligopyridine-galactose conjugates and their metal complexes: a simple entry to multivalent sugar ligands Fulltext Access 13 Pages 2005
Synthesis of diastereoisomeric pairs of novel analogues of d4T having an isochroman glycon moiety; their enzymatic kinetic resolution, their enantiopure synthesis, molecular modeling and NMR structural study Fulltext Access 13 Pages 2005
Stereoselective synthesis of N-protected pyrrolidines via Pd-catalyzed reactions of γ-(N-acylamino) alkenes and γ-(N-Boc-amino) alkenes with aryl bromides Fulltext Access 13 Pages 2005
A highly active catalyst for the reductive cyclization of ortho-nitrostyrenes under mild conditions Fulltext Access 13 Pages 2005
Synthesis of cyclic sulfamoyl carbamates and ureas via ring-closing metathesis Fulltext Access 13 Pages 2005
Application of divergent multi-component reactions in the synthesis of a library of peptidomimetics based on γ-amino-α,β-cyclopropyl acids Fulltext Access 13 Pages 2005
Synthesis of C-5 substituted nucleosides via palladium-catalyzed coupling of dienes and amines Fulltext Access 13 Pages 2005
Enantioselective and regioselective nickel-catalyzed multicomponent coupling of chiral allenes, aromatic aldehydes, and silanes Fulltext Access 13 Pages 2005
Use of bis-(aminol) ethers derived from N-(S)-(â)-α-methylbenzylamine in reactions with resorcinarenes and double Mannich reactions Fulltext Access 13 Pages 2005
Understanding the Polymorphic Behavior of Sibenadet Hydrochloride through Detailed Studies Integrating Structural and Dynamical Assessment Fulltext Access 13 Pages 2005
Sulfoalkyl Ether-Alkyl Ether Cyclodextrin Derivatives, their Synthesis, NMR Characterization, and Binding of 6α-Methylprednisolone Fulltext Access 13 Pages 2005
Comparison of statistical analysis and Bayesian networks in the evaluation of dissolution performance of BCS Class II model drugs Fulltext Access 13 Pages 2005
Reversible Self-Association Increases the Viscosity of a Concentrated Monoclonal Antibody in Aqueous Solution Fulltext Access 13 Pages 2005
Effect Of the Variation in the Ambient Moisture on the Compaction Behavior of Powder Undergoing Roller-Compaction And On The Characteristics Of Tablets Produced From The Post-Milled Granules Fulltext Access 13 Pages 2005
Influence of Ambient Moisture on the Compaction Behavior of Microcrystalline Cellulose Powder Undergoing Uni-Axial Compression and Roller-Compaction: A Comparative Study Using Near-Infrared Spectroscopy Fulltext Access 13 Pages 2005
SCF-Engineered Powders for Delivery of Budesonide from Passive DPI Devices Fulltext Access 13 Pages 2005
Efficient asymmetric synthesis of α-alkylated benzylic methyl sulfonates Fulltext Access 13 Pages 2005
Possible Involvement of Singlet Oxygen Species as Multiple Oxidants in P450 Catalytic Reactions Fulltext Access 13 Pages 2005
L'assistance circulatoire : de l'attente de récupération ou de transplantation à l'implantation définitive Fulltext Access 13 Pages 2005
Quinoxalines XIV.â Synthesis, 1H, 13C, 15N NMR spectroscopic, and quantum chemical study of 1H-pyrazolo[3,4-b]quinoxalines (flavazoles) Fulltext Access 13 Pages 2005
Investigations concerning the organolanthanide and group 3 metallocene-catalyzed cyclization-functionalization of nitrogen-containing dienes Fulltext Access 13 Pages 2005
Mechanistic approaches to asymmetric synthesis of aziridines from guanidinium ylides and aryl aldehydes Fulltext Access 13 Pages 2005
A formal total synthesis of Lycopodium alkaloid, (±)-magellanine, by using the intramolecular Pauson Khand reaction Fulltext Access 13 Pages 2005
Nucleophilic additions of lithiated allylphenylsulfone to nitrones: experimental and theoretical investigations Fulltext Access 13 Pages 2005
A combined experimental and computational strategy in the assignment of absolute configurations of 4-methyl-5-oxo-tetrahydrofuran-3-carboxylic acids and their esters Fulltext Access 13 Pages 2005
Towards the rational design of palladium-N-heterocyclic carbene catalysts by a combined experimental and computational approach Fulltext Access 13 Pages 2005
Palladium-catalyzed cyclization reactions of propargylic carbonates with nucleophiles: a methodology for the syntheses of substituted 2,3-dihydrofurans and benzofurans Fulltext Access 13 Pages 2005
Conformational analysis of new 14-membered ring diketal dilactam macrocycles: molecular mechanics, liquid and solid state NMR studies Fulltext Access 13 Pages 2005
Porphyrins with exocyclic rings. Part 21: Influence of pyrrolic and carbocyclic ring alkyl substituents on the synthesis of porphyrins bearing six-membered exocyclic rings Fulltext Access 13 Pages 2005
Porphyrins with exocyclic rings. Part 20: Synthesis and spectroscopic characterization of porphyrins with fused 2,1,3-benzoxadiazole and 2,1,3-benzoselenadiazole moieties Fulltext Access 13 Pages 2005
Oxidative nucleophilic substitution of hydrogen in nitroarenes with phenylacetic acid derivatives Fulltext Access 13 Pages 2005
The synthesis of a single enantiomer of a major α-mycolic acid of M. tuberculosis Fulltext Access 13 Pages 2005
Synthesis of fused indoles by sequential palladium-catalyzed Heck reaction and N-heteroannulation Fulltext Access 13 Pages 2005
One catalyst for two distinct reactions: sequential asymmetric hetero Diels-Alder reaction and diethylzinc addition Fulltext Access 13 Pages 2005