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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Autonomic imbalance in cardiac surgery: A potential determinant of the failure in remote ischemic preconditioning
Fulltext Access 22 Pages 2018
Fundamental principles of the olfactory code
Fulltext Access 22 Pages 2018
Can we accelerate medicinal chemistry by augmenting the chemist with Big Data and artificial intelligence?
Fulltext Access 22 Pages 2018
Kinetics and metabolism of apocynin in the mouse brain assessed with positron-emission tomography
Fulltext Access 22 Pages 2018
Observation of pain-sensitive points in patients with knee osteoarthritis: A pilot study
Fulltext Access 22 Pages 2018
Impact of processing methods on the dissolution of artemether from two non-ordered mesoporous silicas
Fulltext Access 22 Pages 2018
Nucleobases adsorption studies on silicane layer: A first-principles investigation
Fulltext Access 22 Pages 2018
Tramadol HCl encapsulated niosomes for extended analgesic effect following oral administration
Fulltext Access 22 Pages 2018
Development of novel pyridazinone-based adenosine receptor ligands
Fulltext Access 22 Pages 2018
Visceral theory of sleep and origins of mental disorders
Fulltext Access 22 Pages 2018
Preoperative gastric lavage in gastric cancer patients undergoing surgical, endoscopic or minimally invasive treatment: An oncological measure preventing peritoneal spillage of intragastric cancer cells and development of related metastases
Fulltext Access 22 Pages 2018
Impact of Experimental Variables on the Protein Binding of Tigecycline in Human Plasma as Determined by Ultrafiltration
Fulltext Access 23 Pages 2018
Effect of diaphragmatic breathing exercise on psychological parameters in gestational diabetes: A randomised controlled trial
Fulltext Access 23 Pages 2018
Assessing whether progesterone-matured dendritic cells are responsible for retention of fertilization products in missed abortion
Fulltext Access 23 Pages 2018
Quality markers based on biological activity: A new strategy for the quality control of traditional Chinese medicine
Fulltext Access 23 Pages 2018
Nonclinical data supporting orphan medicinal product designations: lessons from rare neurological conditions
Fulltext Access 23 Pages 2018
Automated Supersaturation Stability Assay to Differentiate Poorly Soluble Compounds in Drug Discovery
Fulltext Access 23 Pages 2018
The effects of urolithins on the response of prostate cancer cells to non-steroidal antiandrogen bicalutamide
Fulltext Access 23 Pages 2018
Lubricant based determination of design space for continuously manufactured high dose paracetamol tablets
Fulltext Access 23 Pages 2018
Physiologically Based Oral Absorption Modelling to Study Gut-Level Drug Interactions
Fulltext Access 23 Pages 2018
Investigation of sustained release mucoadhesive in-situ gel system of Secnidazole for the persistent treatment of vaginal infections
Fulltext Access 23 Pages 2018
Dual stimuli-responsive polypyrrole nanoparticles for anticancer therapy
Fulltext Access 23 Pages 2018
Trigeminal long-term potentiation as a cellular substrate for migraine
Fulltext Access 23 Pages 2018
A cochlear implant loaded with dexamethasone and coated with hyaluronic acid to inhibit fibroblast adhesion and proliferation
Fulltext Access 23 Pages 2018
Ammonia: A novel target for the treatment of non-alcoholic steatohepatitis
Fulltext Access 23 Pages 2018
A double-blind, randomized, placebo-controlled trial evaluating safety and efficacy of an ayurvedic botanical formulation in reducing menopausal symptoms in otherwise healthy women
Fulltext Access 23 Pages 2018
Estimation of crystallinity of indomethacin by usage of terahertz time-domain spectroscopy and calibration curve: Correlation between crystallinity and solubility
Fulltext Access 23 Pages 2018
Perceived fatigue and energy are independent unipolar states: Supporting evidence
Fulltext Access 23 Pages 2018
Aggregating, polarizing, networking - The evolution of cell adhesion codes
Fulltext Access 23 Pages 2018
In memory of Prof. Venkataraman: Recent advances in the synthetic methodologies of flavones
Fulltext Access 23 Pages 2018
A template guided approach to generating cell permeable inhibitors of Staphylococcus aureus biotin protein ligase
Fulltext Access 23 Pages 2018
Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitors
Fulltext Access 23 Pages 2018
Synthesis and antiviral evaluation of cyclopentyl nucleoside phosphonates
Fulltext Access 23 Pages 2018
Probing the early stages of tablet disintegration by stress relaxation measurement
Fulltext Access 23 Pages 2018
Antitussive and expectorant activities of licorice and its major compounds
Fulltext Access 23 Pages 2018
Asymmetric synthesis of secondary benzylic alcohols via arene chromium tricarbonyl complexes
Fulltext Access 23 Pages 2018
Design, in silico prioritization and biological profiling of apoptosis-inducing lactams amenable by the Castagnoli-Cushman reaction
Fulltext Access 23 Pages 2018
Synthesis, molecular docking and biological evaluation of some benzimidazole derivatives as potent pancreatic lipase inhibitors
Fulltext Access 23 Pages 2018
Development and evaluation of thermo-sensitive hydrogel system with nanocomplexes for prolonged subcutaneous delivery of enoxaparin
Fulltext Access 23 Pages 2018
Multi-effects of Resveratrol on stem cell characteristics: Effective dose, time, cell culture conditions and cell type-specific responses of stem cells to Resveratrol
Fulltext Access 24 Pages 2018
The method of quality marker research and quality evaluation of traditional Chinese medicine based on drug properties and effect characteristics
Fulltext Access 24 Pages 2018
Understanding Plasmonic Heat-triggered drug release from gold based nanostructure
Fulltext Access 24 Pages 2018
Nasal patches containing naphazoline for management of nasal impairments
Fulltext Access 24 Pages 2018
Nonlinear Protein Binding: Not What You Think
Fulltext Access 24 Pages 2018
Tyrosinase inhibition by some flavonoids: Inhibitory activity, mechanism by in vitro and in silico studies
Fulltext Access 24 Pages 2018
A Phase 1 Study to Evaluate the Effect of Crushing, Cutting Into Half, or Grinding of Glecaprevir/Pibrentasvir Tablets on Exposures in Healthy Subjects
Fulltext Access 24 Pages 2018
Functionalized nanoliposomes loaded with anti survivin and anti angiogenic agents to enhance the activity of chemotherapy against melanoma by 4-pronged action
Fulltext Access 24 Pages 2018
Characterization of the Hydrodynamics in a Miniaturized Dissolution Apparatus
Fulltext Access 24 Pages 2018
Self-assembly of a ibuprofen-peptide conjugate to suppress ocular inflammation
Fulltext Access 24 Pages 2018
Multimodal doxorubicin loaded magnetic nanoparticles for VEGF targeted theranostics of breast cancer
Fulltext Access 24 Pages 2018
A reusable magnetic nickel nanoparticle based catalyst for the aqueous synthesis of diverse heterocycles and their evaluation as potential anti-bacterial agent
Fulltext Access 24 Pages 2018
The substitution effect of heterocyclic rings to tune the optical and nonlinear optical properties of hybrid chalcones: A comparative study
Fulltext Access 24 Pages 2018
Novel 4-(2-pyrimidinylamino)benzamide derivatives as potent hedgehog signaling pathway inhibitors
Fulltext Access 24 Pages 2018
Computer simulation for the study of the liquid chromatographic separation of explosive molecules
Fulltext Access 24 Pages 2018
A model of optimal protein allocation during phototrophic growth
Fulltext Access 24 Pages 2018
Gamma radiation synthesis and characterization of gentamicin loaded polysaccharide gum based hydrogel wound dressings
Fulltext Access 24 Pages 2018
Personalized medicine in non-small cell lung cancer: a review from a pharmacogenomics perspective
Fulltext Access 24 Pages 2018
Laser-responsive liposome for selective tumor targeting of nitazoxanide nanoparticles
Fulltext Access 24 Pages 2018
Topical formulations of delta-aminolevulinic acid for the treatment of actinic keratosis: Characterization and efficacy evaluation
Fulltext Access 24 Pages 2018
Charged cyclic hexapeptides: Updating molecular descriptors for permeability purposes
Fulltext Access 24 Pages 2018
Peptides as a strategy against biofilm-forming microorganisms: Structure-activity relationship perspectives
Fulltext Access 24 Pages 2018
Investigation of supersaturation and in vitro permeation of the poorly water soluble drug ezetimibe
Fulltext Access 24 Pages 2018
Comparison of dissolution time profiles: No similarity but where is the difference?
Fulltext Access 24 Pages 2018
Intact blood-brain barrier transport of small molecular drugs in animal models of amyloid beta and alpha-synuclein pathology
Fulltext Access 24 Pages 2018
Dual or multi-targeting inhibitors: The next generation anticancer agents
Fulltext Access 24 Pages 2018
Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye
Fulltext Access 24 Pages 2018
Immunogenicity of multi-walled carbon nanotubes functionalized with recombinant protective antigen domain 4 toward development of a nanovaccine against anthrax
Fulltext Access 25 Pages 2018
Promotion of quality standard of Chinese herbal medicine by the integrated and efficacy-oriented quality marker of Effect-constituent Index
Fulltext Access 25 Pages 2018
Insulin resistance, an unmasked culprit in depressive disorders: Promises for interventions
Fulltext Access 25 Pages 2018
Synthesis and anti-fibrosis activity study of 14-deoxyandrographolide-19-oic acid and 14-deoxydidehydroandrographolide-19-oic acid derivatives
Fulltext Access 25 Pages 2018
Left ventricular hypertrophy as protective factor after bypass grafting
Fulltext Access 25 Pages 2018
Modelling information flow along the human connectome using maximum flow
Fulltext Access 25 Pages 2018
Multi-targeted dihydrazones as potent biotherapeutics
Fulltext Access 25 Pages 2018
Retinal pigment epithelial cells as a therapeutic tool and target against retinopathies
Fulltext Access 25 Pages 2018
Strategies for the enhanced intracellular delivery of nanomaterials
Fulltext Access 25 Pages 2018
Analysis of the influence of simulation parameters on biomolecule-linked water networks
Fulltext Access 25 Pages 2018
Adsorption studies of volatile organic compounds on germanene nanotube emitted from banana fruit for quality assessment - A density functional application
Fulltext Access 25 Pages 2018
A computational study on the cisplatin drug interaction with boron nitride nanocluster
Fulltext Access 25 Pages 2018
Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents
Fulltext Access 25 Pages 2018
Synthesis and anticancer activity of new dihydropyrimidinone derivatives
Fulltext Access 25 Pages 2018
Synthesis of proline derived benzenesulfonamides: A potent anti-Trypanosoma brucei gambiense agent
Fulltext Access 25 Pages 2018
New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action
Fulltext Access 25 Pages 2018
Development of anti-fungal pesticides from protein kinase inhibitor-based anticancer agents
Fulltext Access 25 Pages 2018
Emimycin and its nucleoside derivatives: Synthesis and antiviral activity
Fulltext Access 25 Pages 2018
Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid
Fulltext Access 25 Pages 2018
Solvent-free, catalyst-free aza-Michael addition of cyclohexylamine to diethyl maleate: Reaction mechanism and kinetics
Fulltext Access 25 Pages 2018
Towards measuring the semantic capacity of a physical medium demonstrated with elementary cellular automata
Fulltext Access 25 Pages 2018
Reconceptualizing delirium as a disorder of complex system failure
Fulltext Access 25 Pages 2018
Chinese medicine functional diagnosis: An integrative insight to understand rheumatoid arthritis of the hand
Fulltext Access 25 Pages 2018
Dose- and time-dependent pharmacokinetics of apigenin trimethyl ether
Fulltext Access 25 Pages 2018
Effects of enzymatic degradation on dynamic mechanical properties of the vitreous and intravitreal nanoparticle mobility
Fulltext Access 25 Pages 2018
Impact of change of matrix crystallinity and polymorphism on ovalbumin release from lipid-based implants
Fulltext Access 25 Pages 2018
Folic acid-chitosan-alginate nanocomplexes for multiple delivery of chemotherapeutic agents
Fulltext Access 25 Pages 2018
Understanding tablet defects in commercial manufacture and transfer
Fulltext Access 25 Pages 2018
Formulation, characterization and cytotoxicity evaluation of ketotifen-loaded nanostructured lipid carriers
Fulltext Access 25 Pages 2018
Modulation of transdermal drug delivery with coated microneedles
Fulltext Access 25 Pages 2018
A comparative study on the potentials of nanoliposomes and nanoethosomes for Fluconazole delivery
Fulltext Access 25 Pages 2018
Confirmation of More Stable Polymorphic Form of Etoricoxib at Room Temperature
Fulltext Access 25 Pages 2018
Pharmacological Efficacy/Toxicity of Drugs: A Comprehensive Update About the Dynamic Interplay of Microbes
Fulltext Access 25 Pages 2018
Enhanced Dissolution of a Porous Carrier-Containing Ternary Amorphous Solid Dispersion System Prepared by a Hot Melt Method
Fulltext Access 25 Pages 2018
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