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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Computational drug repurposing to predict approved and novel drug-disease associations
Fulltext Access 15 Pages 2018
Synthesis of a cisplatin derivative from lithocholic acid
Fulltext Access 15 Pages 2018
Bioorthogonal chemistry: Optimization and application updates during 2013-2017
Fulltext Access 15 Pages 2018
Drug permeability profiling using cell-free permeation tools: Overview and applications
Fulltext Access 15 Pages 2018
The neuroprotective role of the brain opioid system in stroke injury
Fulltext Access 15 Pages 2018
Adaptive pathway development for Fabry disease: a clinical approach
Fulltext Access 15 Pages 2018
Recent topics of the natural product synthesis by Horner-Wadsworth-Emmons reaction
Fulltext Access 15 Pages 2018
Recurrent bacterial translocation from gut and sepsis in Head and neck cancer patients and its prevention by probiotics
Fulltext Access 15 Pages 2018
Navigating albumin-based nanoparticles through various drug delivery routes
Fulltext Access 15 Pages 2018
Drugs as habitable planets in the space of dark chemical matter
Fulltext Access 15 Pages 2018
First homology model of Plasmodium falciparum glucose-6-phosphate dehydrogenase: Discovery of selective substrate analog-based inhibitors as novel antimalarial agents
Fulltext Access 15 Pages 2018
Topics of 1,3-diphosphacyclobutane-2,4-diyl derivatives: Structural aspects and functionality of isolable heavier congeners of cyclobutane-1,3-diyl and the related molecules
Fulltext Access 15 Pages 2018
Structural Characterization and Formulation Development of a Trivalent Equine Encephalitis Virus-Like Particle Vaccine Candidate
Fulltext Access 15 Pages 2018
Synthesis, structure and bioactivity of primary sulfamate-containing natural products
Fulltext Access 15 Pages 2018
Development of matrix metalloproteinase-13 inhibitors - A structure-activity/structure-property relationship study
Fulltext Access 15 Pages 2018
The hitchhiker's guide to the chemical-biological galaxy
Fulltext Access 15 Pages 2018
Peptides for optical medical imaging and steps towards therapy
Fulltext Access 15 Pages 2018
Microbiota potential for the treatment of sexual dysfunction
Fulltext Access 15 Pages 2018
Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators
Fulltext Access 15 Pages 2018
Corticosteroids and perinatal hypoxic-ischemic brain injury
Fulltext Access 15 Pages 2018
Effect of Water on the Chemical Stability of Amorphous Pharmaceuticals: 2. Deamidation of Peptides and Proteins
Fulltext Access 15 Pages 2018
The pruritus of cholestasis: From bile acids to opiate agonists: Relevant after all these years
Fulltext Access 15 Pages 2018
Dendrimer nanohybrid carrier systems: an expanding horizon for targeted drug and gene delivery
Fulltext Access 15 Pages 2018
The lamin code
Fulltext Access 15 Pages 2018
The evolutionary dynamics of language
Fulltext Access 16 Pages 2018
Solid lipid nanoparticles: Reversal of tamoxifen resistance in breast cancer
Fulltext Access 16 Pages 2018
The end-stage failing human myocardium - Where changes in ultrastructure of human cardiac muscle cells do not appear to dictate clinical outcomes
Fulltext Access 16 Pages 2018
Conquering amide planarity: Structural distortion and its hidden reactivity
Fulltext Access 16 Pages 2018
Designing an intuitive web application for drug discovery scientists
Fulltext Access 16 Pages 2018
Would glucagon-like peptide-1 receptor agonists have efficacy in binge eating disorder and bulimia nervosa? A review of the current literature
Fulltext Access 16 Pages 2018
Computational prediction of chemical reactions: current status and outlook
Fulltext Access 16 Pages 2018
Acupuncture for cancer patients undergoing radiotherapy: Protocol for a programme of research
Fulltext Access 16 Pages 2018
Evaluation of isoprinosine to be repurposed as an adjunct anti-tuberculosis chemotherapy
Fulltext Access 16 Pages 2018
Medicinal chemistry in drug discovery in big pharma: past, present and future
Fulltext Access 16 Pages 2018
Marketing authorisation of orphan medicines in Europe from 2000 to 2013
Fulltext Access 16 Pages 2018
Elevated endogenous opioids in obstructive jaundice: The possible skin mechanisms
Fulltext Access 16 Pages 2018
Molecular targets and pathways for the treatment of visceral leishmaniasis
Fulltext Access 16 Pages 2018
Discovery of small molecule protease inhibitors by investigating a widespread human gut bacterial biosynthetic pathway
Fulltext Access 16 Pages 2018
Synthesis, biological activity and structure activity relationship studies of novel conazole analogues via conventional, microwave and ultrasound mediated techniques
Fulltext Access 16 Pages 2018
Is melatonin effective for pruritus caused by liver disease?
Fulltext Access 16 Pages 2018
Opportunity and challenges of nasal powders: Drug formulation and delivery
Fulltext Access 16 Pages 2018
Synthesis of cationic glucosamino nucleic acids for stabilizing oligonucleotides
Fulltext Access 16 Pages 2018
From nature to creation: Going around in circles, the art of peptide cyclization
Fulltext Access 16 Pages 2018
Improvement of a mixture experiment model relating the component proportions to the size of nanonized itraconazole particles in extemporary suspensions
Fulltext Access 16 Pages 2018
Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents
Fulltext Access 16 Pages 2018
Functional connectivity, behavioral and dopaminergic alterations 24 hours following acute exposure to synthetic bath salt drug methylenedioxypyrovalerone
Fulltext Access 16 Pages 2018
Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study
Fulltext Access 16 Pages 2018
A reassessment of mycophenolic acid as a lead compound for the development of inhibitors of chikungunya virus replication
Fulltext Access 16 Pages 2018
Application of a catalyst-free Domino Mannich/Friedel-Crafts alkylation reaction for the synthesis of novel tetrahydroquinolines of potential antitumor activity
Fulltext Access 16 Pages 2018
Covalently linked dimer of chlorophyll-a derivative with an amide bond and its folded conformer
Fulltext Access 16 Pages 2018
Caffeic acid phenethyl ester synergistically enhances the antifungal activity of fluconazole against resistant Candida albicans
Fulltext Access 16 Pages 2018
Loop modelling 1.0
Fulltext Access 16 Pages 2018
Recent progresses in the synthesis of functionalized isoxazoles
Fulltext Access 16 Pages 2018
A discriminative test among the different theories proposed to explain the origin of the genetic code: The coevolution theory finds additional support
Fulltext Access 16 Pages 2018
Computational protein design and protein-ligand interaction studies for the improvement of organophosphorus degrading potential of Deinococcus radiodurans
Fulltext Access 16 Pages 2018
Design of a Small-Scale Multi-Inlet Vortex Mixer for Scalable Nanoparticle Production and Application to the Encapsulation of Biologics by Inverse Flash NanoPrecipitation
Fulltext Access 17 Pages 2018
Nano spray drying: A novel technique to prepare well-defined surface coatings for medical implants
Fulltext Access 17 Pages 2018
Synthesis and characterization of silica aerogel as a promising drug carrier system
Fulltext Access 17 Pages 2018
Analysis of the Postoperative Periarticular Environment and Influence on Sustained Drug Delivery From a Gel Formulation
Fulltext Access 17 Pages 2018
The potential role of endocrine disrupting chemicals in cellulite
Fulltext Access 17 Pages 2018
Do the key prognostic factors for non-specific neck pain have moderation effects? - A study protocol
Fulltext Access 17 Pages 2018
Immediate and complete restoration of peripheral nerve function after injury is attainable by a combination of surgical and chemical interventions
Fulltext Access 17 Pages 2018
Could the screening for correct oral health reduce the impact of death due to bolus asphyxia in adult patients? A forensic case report
Fulltext Access 17 Pages 2018
Changes in the hippocampal and peripheral phospholipid profiles are associated with neurodegeneration hallmarks in a long-term global cerebral ischemia model: Attenuation by Linalool
Fulltext Access 17 Pages 2018
Axially chiral tridentate isoquinoline derived ligands for diethylzinc addition to aldehydes
Fulltext Access 17 Pages 2018
Rate of small-molecular drug transport across the blood-brain barrier in a pericyte-deficient state
Fulltext Access 17 Pages 2018
Differential proteomics analysis of bile between gangrenous cholecystitis and chronic cholecystitis
Fulltext Access 17 Pages 2018
Design, synthesis and anti-mycobacterial activity evaluation of benzofuran-isatin hybrids
Fulltext Access 17 Pages 2018
What is code biology?
Fulltext Access 17 Pages 2018
Loading-device effects on the protein-unfolding mechanisms using molecular-dynamic simulations
Fulltext Access 17 Pages 2018
Synthesis of matrinic amide derivatives containing 1,3,4-thiadiazole scaffold as insecticidal/acaricidal agents
Fulltext Access 17 Pages 2018
Identification of novel indole based heterocycles as selective estrogen receptor modulator
Fulltext Access 17 Pages 2018
Design, synthesis and anticancer studies of novel aminobenzazolyl pyrimidines as tyrosine kinase inhibitors
Fulltext Access 17 Pages 2018
Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist
Fulltext Access 17 Pages 2018
Synthesis of novel quinolinomatrine derivatives and their insecticidal/acaricidal activities
Fulltext Access 17 Pages 2018
Identification of fused pyrimidines as interleukin 17 secretion inhibitors
Fulltext Access 17 Pages 2018
Tamoxifen a pioneering drug: An update on the therapeutic potential of tamoxifen derivatives
Fulltext Access 17 Pages 2018
Strategic innovations for the synthesis of vinigrol
Fulltext Access 17 Pages 2018
Recent developments in the synthesis of prosophylline and its derivatives
Fulltext Access 17 Pages 2018
Recent advances in acetylene-based helical oligomers and polymers: Synthesis, structures, and properties
Fulltext Access 17 Pages 2018
Mango leaf extract synthesized silver nanorods exert anticancer activity on breast cancer and colorectal carcinoma cells
Fulltext Access 17 Pages 2018
Composite smart mesoporous silica nanoparticles as promising therapeutic and diagnostic candidates: Recent trends and applications
Fulltext Access 17 Pages 2018
Filtration membranes - Scavengers for leachables?
Fulltext Access 17 Pages 2018
Computational modeling approaches to quantitative structure-binding kinetics relationships in drug discovery
Fulltext Access 17 Pages 2018
Redundancy in two major compound databases
Fulltext Access 17 Pages 2018
The extent and effects of patient involvement in pictogram design for written drug information: a short systematic review
Fulltext Access 17 Pages 2018
The positive impacts of Real-World Data on the challenges facing the evolution of biopharma
Fulltext Access 17 Pages 2018
Privileged portal metastasis of hepatocellular carcinoma in light of co-evolution of a visceral portal system and the liver in the chordate lineage: a search for therapeutic targets
Fulltext Access 17 Pages 2018
Present drug-likeness filters in medicinal chemistry during the hit and lead optimization process: how far can they be simplified?
Fulltext Access 17 Pages 2018
Network-based technologies for early drug discovery
Fulltext Access 17 Pages 2018
Anticancer activity of seaweeds
Fulltext Access 17 Pages 2018
Targeting an oncogenic kinase/phosphatase signaling network for cancer therapy
Fulltext Access 17 Pages 2018
Review of the fabrication techniques and applications of polymeric electrospun nanofibers for drug delivery systems
Fulltext Access 18 Pages 2018
Designing the new generation of intelligent biocompatible carriers for protein and peptide delivery
Fulltext Access 18 Pages 2018
Imidazopyridine linked triazoles as tubulin inhibitors, effectively triggering apoptosis in lung cancer cell line
Fulltext Access 18 Pages 2018
Therapeutic peptides: Historical perspectives, current development trends, and future directions
Fulltext Access 18 Pages 2018
Increased building block access through collaboration
Fulltext Access 18 Pages 2018
Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety
Fulltext Access 18 Pages 2018
The bioelectric code: An ancient computational medium for dynamic control of growth and form
Fulltext Access 18 Pages 2018
The search image as link between sensation, perception and action
Fulltext Access 18 Pages 2018
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