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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Paliperidone ascending controlled-release pellets with osmotic core and driven by delayed osmotic pressure
Fulltext Access 18 Pages 2018
Genetic coding algorithm for sense and antisense peptide interactions
Fulltext Access 18 Pages 2018
The bioelectric code: An ancient computational medium for dynamic control of growth and form
Fulltext Access 18 Pages 2018
Methodologies for assessing the acceptability of oral formulations among children and older adults: a systematic review
Fulltext Access 18 Pages 2018
Molecular motor translocation kinetics: Application of Monte Carlo computer simulations to determine microscopic kinetic parameters
Fulltext Access 18 Pages 2018
The impact of age on radium-223 distribution and an evaluation of molecular imaging surrogates
Fulltext Access 18 Pages 2018
Designing the new generation of intelligent biocompatible carriers for protein and peptide delivery
Fulltext Access 18 Pages 2018
Oropharyngeal dysphagia and its related health problems in Iranian elderly people: A scope of work for the future
Fulltext Access 18 Pages 2018
Basil oil-nanoemulsions: Development, cytotoxicity and evaluation of antioxidant and antimicrobial potential
Fulltext Access 18 Pages 2018
Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety
Fulltext Access 18 Pages 2018
Scrub typhus re-emergence in India: Contributing factors and way forward
Fulltext Access 18 Pages 2018
Evaluation of alkylating pyrrole-imidazole polyamide conjugates by a novel method for high-throughput sequencer
Fulltext Access 18 Pages 2018
Therapeutic peptides: Historical perspectives, current development trends, and future directions
Fulltext Access 18 Pages 2018
Structure-based methods to predict mutational resistance to diarylpyrimidine non-nucleoside reverse transcriptase inhibitors
Fulltext Access 18 Pages 2018
Accuracy of movement quality screening to document effects of neuromuscular control retraining exercises in a young ex-footballer with hip and groin symptoms: A proof of concept case study
Fulltext Access 18 Pages 2018
Review of the fabrication techniques and applications of polymeric electrospun nanofibers for drug delivery systems
Fulltext Access 18 Pages 2018
Imidazopyridine linked triazoles as tubulin inhibitors, effectively triggering apoptosis in lung cancer cell line
Fulltext Access 18 Pages 2018
Promiscuous enzyme-catalyzed cascade reaction: Synthesis of xanthone derivatives
Fulltext Access 18 Pages 2018
Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4,6-dichlorophenyl-pyridines
Fulltext Access 18 Pages 2018
Solid lipid nanoparticles of Vancomycin loaded with Ellagic acid as a tool for overcoming nephrotoxic side effects: Preparation, characterization, and nephrotoxicity evaluation
Fulltext Access 19 Pages 2018
A recognition mechanism study: Luminescent metal-organic framework for the detection of nitro-explosives
Fulltext Access 19 Pages 2018
Role of protein in healthy ageing
Fulltext Access 19 Pages 2018
Research of novel anticancer agents targeting arginase inhibition
Fulltext Access 19 Pages 2018
Cartilage degradation in osteoarthritis: A process of osteochondral remodeling resembles the endochondral ossification in growth plate?
Fulltext Access 19 Pages 2018
Real world big data for clinical research and drug development
Fulltext Access 19 Pages 2018
Alternative fluorophores designed for advanced molecular imaging
Fulltext Access 19 Pages 2018
Different types, applications and limits of enabling excipients of pharmaceutical dosage forms
Fulltext Access 19 Pages 2018
Selection rules on initial structures in parallel cascade selection molecular dynamics affect conformational sampling efficiency
Fulltext Access 19 Pages 2018
Safety and clinical efficacy of tenvermectin, a novel antiparasitic 16-membered macrocyclic lactone antibiotics
Fulltext Access 19 Pages 2018
A novel Barton decarboxylation produces a 1,4-phenyl radical rearrangement domino reaction
Fulltext Access 19 Pages 2018
Cell-based assay for characterizing cell adhesion properties of active targeted nanoparticles under static and flow condition using an integrated flow chamber
Fulltext Access 19 Pages 2018
Polymer-coated mesoporous silica nanoparticles for controlled release of the prodrug sulfasalazine
Fulltext Access 19 Pages 2018
Lipid-polymer hybrid nanocarrier-mediated cancer therapeutics: current status and future directions
Fulltext Access 19 Pages 2018
Size controlled fabrication of cellulose nanoparticles for drug delivery applications
Fulltext Access 19 Pages 2018
Bioavailability of resveratrol: Possibilities for enhancement
Fulltext Access 19 Pages 2018
Industry's View on Using Quality Control, Biorelevant, and Clinically Relevant Dissolution Tests for Pharmaceutical Development, Registration, and Commercialization
Fulltext Access 19 Pages 2018
The Selection of a Pharmaceutical Salt-The Effect of the Acidity of the Counterion on Its Solubility and Potential Biopharmaceutical Performance
Fulltext Access 19 Pages 2018
Optical illusions and life-threatening traffic crashes: A perspective on aerial perspective
Fulltext Access 19 Pages 2018
Discovery and identification of quality markers of Chinese medicine based on pharmacokinetic analysis
Fulltext Access 19 Pages 2018
Silver-nanoparticles increase bactericidal activity and radical oxygen responses against bacterial pathogens in human osteoclasts
Fulltext Access 19 Pages 2018
The selectivity and bioavailability improvement of novel oral anticoagulants: An overview
Fulltext Access 19 Pages 2018
Recent examples of the use of biocatalysts with high accessibility and availability in natural product synthesis
Fulltext Access 19 Pages 2018
Halogenated quinolines bearing polar functionality at the 2-position: Identification of new antibacterial agents with enhanced activity against Staphylococcus epidermidis
Fulltext Access 19 Pages 2018
Synthesis and biological evaluation of novel larotaxel analogues
Fulltext Access 19 Pages 2018
Synthesis of pyrazole acrylic acid based oxadiazole and amide derivatives as antimalarial and anticancer agents
Fulltext Access 19 Pages 2018
Chiral 2-(2-hydroxyaryl)alcohols (HAROLs) with a 1,4-diol scaffold as a new family of ligands and organocatalysts
Fulltext Access 19 Pages 2018
Recent advances in Garratt-Braverman cyclization: Mechanistic and synthetic explorations
Fulltext Access 19 Pages 2018
Representational fluidity in embodied (artificial) cognition
Fulltext Access 19 Pages 2018
Mechanisms of directed evolution of morphological structures and the problems of morphogenesis
Fulltext Access 19 Pages 2018
Tuning the biological activity of cationic anthraquinone analogues specifically toward Staphylococcus aureus
Fulltext Access 19 Pages 2018
Publisher's Note
Fulltext Access 19 Pages 2018
Complex molecules, clever solutions - Enzymatic approaches towards natural product and active agent syntheses
Fulltext Access 19 Pages 2018
Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity
Fulltext Access 20 Pages 2018
Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities
Fulltext Access 20 Pages 2018
A randomized controlled trial comparing electroacupuncture with manual acupuncture for motor function recovery after ischemic stroke
Fulltext Access 20 Pages 2018
European regulation model for herbal medicine: The assessment of the EU monograph and the safety and efficacy evaluation in marketing authorization or registration in Member States
Fulltext Access 20 Pages 2018
Probing the Amorphous State of Pharmaceutical Compounds Within Mesoporous Material Using Pair Distribution Function Analysis
Fulltext Access 20 Pages 2018
Pushing the Limits of Molecular Crystal Structure Determination From Powder Diffraction Data in High-Throughput Chemical Environments
Fulltext Access 20 Pages 2018
Biorelevant Drug Solubility Enhancement Modeled by a Linear Solvation Energy Relationship
Fulltext Access 20 Pages 2018
Resveratrol combined with total flavones of hawthorn alleviate the endothelial cells injury after coronary bypass graft surgery
Fulltext Access 20 Pages 2018
Transparent nontoxic antibacterial wound dressing based on silver nano particle/bacterial cellulose nano composite synthesized in the presence of tripolyphosphate
Fulltext Access 20 Pages 2018
Topical drug delivery to the posterior segment of the eye: Dexamethasone concentrations in various eye tissues after topical administration for up to 15 days to rabbits
Fulltext Access 20 Pages 2018
Design and synthesis of new antitumor agents with the 1,7-epoxycyclononane framework. Study of their anticancer action mechanism by a model compound
Fulltext Access 20 Pages 2018
Nanoimprinting of biomedical polymers reduces candidal physical adhesion
Fulltext Access 20 Pages 2018
A road to bring Brij52 back to attention: Shear stress sensitive Brij52 niosomal carriers for targeted drug delivery to obstructed blood vessels
Fulltext Access 20 Pages 2018
Design, synthesis and biological evaluation of ring A modified 11-keto-boswellic acid derivatives as Pin1 inhibitors with remarkable anti-prostate cancer activity
Fulltext Access 20 Pages 2018
A structure-based design approach to advance the allyltyrosine-based series of HIV integrase inhibitors
Fulltext Access 20 Pages 2018
Risk factors for readmission of rheumatoid arthritis patients receiving integrative medicine: A retrospective analysis
Fulltext Access 20 Pages 2018
Concentration-dependent plasma protein binding: Expect the unexpected
Fulltext Access 20 Pages 2018
When fragments link: a bibliometric perspective on the development of fragment-based drug discovery
Fulltext Access 20 Pages 2018
Thiazolidinediones as antidiabetic agents: A critical review
Fulltext Access 20 Pages 2018
Design, synthesis and biological evaluation of benzofuran appended benzothiazepine derivatives as inhibitors of butyrylcholinesterase and antimicrobial agents
Fulltext Access 20 Pages 2018
Controlling the burst release of doxorubicin from polymeric depots via adjusting hydrophobic/hydrophilic properties
Fulltext Access 20 Pages 2018
Glycosylated tris-bipyridine ferrous complexes for probing a mechanism behind carbohydrate-carbohydrate interactions: Spatial carbohydrate packing of glycoclusters changes on additions of salts in carbohydrate- and anion-dependent manners
Fulltext Access 21 Pages 2018
Efficient synthesis of alkynyl amides via aminocarbonylation of iodoalkynes
Fulltext Access 21 Pages 2018
Peptide therapeutics from venom: Current status and potential
Fulltext Access 21 Pages 2018
The evolution of the genetic code: Impasses and challenges
Fulltext Access 21 Pages 2018
The complex associations between obstructive sleep apnea and auto-immune disorders: A review
Fulltext Access 21 Pages 2018
Synthesis of novel antiproliferative hybrid bis-(3-indolyl)methane phosphonate derivatives
Fulltext Access 21 Pages 2018
Making All Medications Gluten Free
Fulltext Access 21 Pages 2018
A Platform for Preparing Homogeneous Proteinaceous Subvisible Particles With Distinct Morphologies
Fulltext Access 21 Pages 2018
Identification of cisapride as new inhibitor of putrescine uptake in Trypanosoma cruzi by combined ligand- and structure-based virtual screening
Fulltext Access 21 Pages 2018
Platanic acid: A new scaffold for the synthesis of cytotoxic agents
Fulltext Access 21 Pages 2018
Roles of alcohol desolvating agents on the size control of bovine serum albumin nanoparticles in drug delivery system
Fulltext Access 21 Pages 2018
The sugar code: Why glycans are so important
Fulltext Access 21 Pages 2018
Poly(methyl methacrylate) salt as film forming material to design orodispersible films
Fulltext Access 21 Pages 2018
Oxidopyrylium [5+2] cycloaddition chemistry: Historical perspective and recent advances (2008-2018)
Fulltext Access 21 Pages 2018
Unique features of nucleotide and codon usage patterns in mycoplasmas revealed by information entropy
Fulltext Access 21 Pages 2018
A limit in the dynamic increase in the accuracy of group migration
Fulltext Access 21 Pages 2018
Continuous twin screw wet granulation: The combined effect of process parameters on residence time, particle size, and granule morphology
Fulltext Access 22 Pages 2018
Preoperative gastric lavage in gastric cancer patients undergoing surgical, endoscopic or minimally invasive treatment: An oncological measure preventing peritoneal spillage of intragastric cancer cells and development of related metastases
Fulltext Access 22 Pages 2018
Nucleobases adsorption studies on silicane layer: A first-principles investigation
Fulltext Access 22 Pages 2018
Stem cells as vehicles and targets of nanoparticles
Fulltext Access 22 Pages 2018
Towards carborane-functionalised structures for the treatment of brain cancer
Fulltext Access 22 Pages 2018
Synthesis and biological activity of apratoxin derivatives
Fulltext Access 22 Pages 2018
Observation of pain-sensitive points in patients with knee osteoarthritis: A pilot study
Fulltext Access 22 Pages 2018
Mechanistic studies of the antibiofilm activity and synergy with antibiotics of isosorbide mononitrate
Fulltext Access 22 Pages 2018
Impact of processing methods on the dissolution of artemether from two non-ordered mesoporous silicas
Fulltext Access 22 Pages 2018
Tramadol HCl encapsulated niosomes for extended analgesic effect following oral administration
Fulltext Access 22 Pages 2018
Visceral theory of sleep and origins of mental disorders
Fulltext Access 22 Pages 2018
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