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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Can the surface color of pharmaceutical tablets be used as a unique product identifier?
Fulltext Access 6 Pages 2017
Gadolinium-based nanoparticles as sensitizing agents to carbon ions in head and neck tumor cells
Fulltext Access 6 Pages 2017
Aged garlic extract exerts endothelium-dependent vasorelaxant effect on rat aorta by increasing nitric oxide production
Fulltext Access 6 Pages 2017
The kynurenine pathway: Towards metabolic equilibrium
Fulltext Access 6 Pages 2017
Lutein and atherosclerosis: Belfast versus Toulouse revisited
Fulltext Access 6 Pages 2017
Iron accumulation, glutathione depletion, and lipid peroxidation must occur simultaneously during ferroptosis and are mutually amplifying events
Fulltext Access 6 Pages 2017
Cognitive impairment in diabetes and poor glucose utilization in the intracellular neural milieu
Fulltext Access 6 Pages 2017
The network model of delirium
Fulltext Access 6 Pages 2017
Connecting the dots: Overlaps between autism and cancer suggest possible common mechanisms regarding signaling pathways related to metabolic alterations
Fulltext Access 6 Pages 2017
Hypothesis: Co-transfer of genuine embryos and implantation-promoting compounds via artificial containers improve endometrium receptivity
Fulltext Access 6 Pages 2017
An intramedullary nail coated with antibiotic and growth factor nanoparticles: An individualized state-of-the-art treatment for chronic osteomyelitis with bone defects
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Chasing the top quartile of cross-sectional data: Is it possible with resistance training?
Fulltext Access 6 Pages 2017
Exploring the safety and clinical use of herbal medicine in the contemporary Ghanaian context: A descriptive qualitative study
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Highly enantioselective asymmetric reactions involving zinc ions promoted by chiral aziridine alcohols
Fulltext Access 6 Pages 2017
Effect of coexisting atorvastatin calcium on in vitro uremic-like-toxin adsorption in gastrointestinal tract model solution by spherical carbon adsorbent for chronic renal failure therapy
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Liquid crystalline microspheres for 5-fluorouracil specific release
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Evaluation of peptide drug delivery via skin barrier-impact of permeation enhancers
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The influence of cetomacrogol ointment processing on structure: A definitive screening design
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Evaluation of paeonol-loaded transethosomes as transdermal delivery carriers
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Effect of lipid emulsion infusion on paliperidone pharmacokinetics in the acute overdose rat model: A potential emergency treatment for paliperidone intoxication
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Determination of the concentration of major active anti-emetic constituents within commercial ginger food products and dietary supplements
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The topological phase diagram of cimetidine: A case of overall monotropy
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Nonlinear relationship between enteric-coated mycophenolate sodium dose and mycophenolic acid exposure in Han kidney transplantation recipients
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Advances in ultrasound-targeted microbubble-mediated gene therapy for liver fibrosis
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Deorphanization strategies for dark chemical matter
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New Biosilified Pd-lipase hybrid biocatalysts for dynamic resolution of amines
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Stability Orders of Acetaminophen and Theophylline Co-crystals Determined by Co-crystal Former Exchange Reactions and Their Correlation With In Silico and Thermal Parameters
Fulltext Access 6 Pages 2017
Label-Free Measurements of Tenofovir Diffusion Coefficients in a Microbicide Gel Using Raman Spectroscopy
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Midyear Commentary on Trends in Drug Delivery and Clinical Translational Medicine
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Sample Size for Tablet Compression and Capsule Filling Events During Process Validation
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Application of membrane-selective electrodes for the determination of Tiemonium methylsulphate
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Neuroprotective effects of potassium channel openers on cerebral ischemia-reperfusion injury in diabetic rats
Fulltext Access 6 Pages 2017
Pharmacological and phytochemical studies of Alangium salvifolium Wang. - A review
Fulltext Access 6 Pages 2017
Experimental animal models used for evaluation of potential immunomodulators: A mini review
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Enzyme-catalyzed peptide cyclization
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Recent advances in diphosphination of alkynes and alkenes
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Concise synthesis and revision of the proposed biogenesis of helicascolides
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The synthesis of lactone-bridged 1,3,5-triphenylbenzene derivatives as pi-expanded coumarin triskelions
Fulltext Access 6 Pages 2017
A new integrated symmetrical table for genetic codes
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Synthesis of pyrrolo-heterocycles via Pd-loaded zeolite catalyzed annulation of o- haloaromatic amine with terminal alkynes
Fulltext Access 6 Pages 2017
Novel potentially antifungal hybrids of 5-flucytosine and fluconazole: Design, synthesis and bioactive evaluation
Fulltext Access 6 Pages 2017
Role of the sugar moiety on the opioid receptor binding and conformation of a series of enkephalin neoglycopeptides
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Synthesis and anticancer activity of novel aza-artemisinin derivatives
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A stereoselective, catalytic strategy for the in-flow synthesis of advanced precursors of rasagiline and tamsulosin
Fulltext Access 6 Pages 2017
A continuous flow synthesis and derivatization of 1,2,4-thiadiazoles
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High throughput photo-oxidations in a packed bed reactor system
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A photochemical flow reactor for large scale syntheses of aglain and rocaglate natural product analogues
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Photodynamic therapy of human biliary cancer cell line using combination of phosphorus porphyrins and light emitting diode
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Concise asymmetric synthesis of the sex pheromone of the tea tussock moth
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Graphical contents list
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Development of 5-hydroxypyrazole derivatives as reversible inhibitors of lysine specific demethylase 1
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Synthesis of heterocyclic compounds with adamantane-like cage structures consisting of phosphorus, sulfur, and carbon
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New generation of tetrapyrazolic macrocycles: Synthesis and examination of their complexation properties and antibacterial activity
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Towards the directional transport of molecules on surfaces
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Unsymmetrical disulfide and sulfenamide synthesis via reactions of thiosulfonates with thiols or amines
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Construction of new fluorophores by Diels-Alder reaction of diacenaphthothiophenes
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Synthesis and properties of 2-deoxy-2-fluoromannosyl phosphate derivatives
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A mild and one-step synthesis of 2,8-dioxabicyclo [3.3.1] nonane derivatives via classical Knoevenagel condensation
Fulltext Access 6 Pages 2017
A rapid entry into thioflavanones via conjugate additions of diarylcuprates to thiochromones
Fulltext Access 6 Pages 2017
New steroidal saponins with l-arabinose moiety from the rhizomes of Smilax scobinicaulis
Fulltext Access 6 Pages 2017
Easy and rapid preparation of benzoylhydrazides and their diazene derivatives as inhibitors of 15-lipoxygenase
Fulltext Access 6 Pages 2017
A path based approach to assessing molecular complexity
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Anti-influenza activity of monoterpene-containing substituted coumarins
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Highly selective intermolecular one-pot three component 1,3-dipolar cycloaddition reaction of aldehydes, with phosphonates and proline
Fulltext Access 6 Pages 2017
Synthesis and biological evaluation of novel 1,2,3-triazole derivatives as anti-tubercular agents
Fulltext Access 6 Pages 2017
Bioreductively activatable prodrug conjugates of phenstatin designed to target tumor hypoxia
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Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids
Fulltext Access 6 Pages 2017
Synthesis and structure-activity relationship studies of phenolic hydroxyl derivatives based on quinoxalinone as aldose reductase inhibitors with antioxidant activity
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Characterisation of a novel coumarin-based fluorescent probe for monitoring nitric oxide production in macrophages
Fulltext Access 6 Pages 2017
Graphical contents list
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Stereochemistry abstracts
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Enantioselective total synthesis of a natural hydrocarbazolone alkaloid, identification of its stereochemistry, and revision of its spectroscopic data
Fulltext Access 6 Pages 2017
Application of sulfonyl chlorides and chiral amines in the efficient synthesis of nonracemic sulfinamides
Fulltext Access 6 Pages 2017
Effects of metal-ion replacement on pyrazinamidase activity: A quantum mechanical study
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Evaluation of the absolute affinity of neuraminidase inhibitor using steered molecular dynamics simulations
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Synthesis of new chiral fluorescent sensors and their applications in enantioselective discrimination
Fulltext Access 6 Pages 2017
On plant roots logical gates
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Aerobic oxidative homocoupling reaction of anilides using heterogeneous metal catalysts
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Synthesis of various 6-substituted 1,4,5,6-tetrahydropyridazines by substitution of a 1,4,5,6-tetrahydro-6-tosylhydrazinopyridazines
Fulltext Access 6 Pages 2017
The organocatalytic desymmetrization of meso-ferrocene anhydride
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Palladium-catalyzed synthesis of indole fused coumarins via cross-dehydrogenative coupling
Fulltext Access 6 Pages 2017
Aerobic oxidation of benzyl alcohols through biosynthesized palladium nanoparticles mediated by Oak fruit bark extract as an efficient heterogeneous nanocatalyst
Fulltext Access 6 Pages 2017
Room-temperature synthesis of pharmaceutically important carboxylic acids bearing the 1,2,4-oxadiazole moiety
Fulltext Access 6 Pages 2017
Catalyst-free allylation of 2-aminophenol-derived aldimines with allyltrichlorosilane under thermal conditions
Fulltext Access 6 Pages 2017
Thio acid-mediated conversion of azides to amides - Exploratory studies en route to oroidin alkaloids
Fulltext Access 6 Pages 2017
Facile removal of tosyl chloride from tosylates using cellulosic materials, e.g., filter paper
Fulltext Access 6 Pages 2017
Synthesis of 2-phenyl pyridine derivatives from aryl ketones and 1,3-diaminopropane using palladium acetate as a catalyst
Fulltext Access 6 Pages 2017
Synthesis and characterization of novel flavonoid derivatives via sequential phosphorylation of quercetin
Fulltext Access 6 Pages 2017
Efficient synthesis of antisense oligodeoxyribonucleotide phosphorothioates
Fulltext Access 6 Pages 2017
Design and synthesis of chiral 1,10-phenanthroline ligand, and application in palladium catalyzed asymmetric 1,4-addition reactions
Fulltext Access 6 Pages 2017
Azo-pyrene-based fluorescent sensor of reductive cleavage of isomeric azo functional group
Fulltext Access 6 Pages 2017
Synthesis of resorcinarene phosphonium salts and the effect of counteranion on their structure
Fulltext Access 6 Pages 2017
Sulfur promoted decarboxylative thioamidation of carboxylic acids using formamides as amine proxy
Fulltext Access 6 Pages 2017
The first stereoselective synthesis of the natural product, rotenone
Fulltext Access 6 Pages 2017
Visible-light-induced synthesis of benzothiophenes and benzoselenophenes via the annulation of thiophenols or 1,2-diphenyldiselane with alkynes
Fulltext Access 6 Pages 2017
Synthesis of new 3-cyanoacetamide pyrrole and 3-acetonitrile pyrrole derivatives
Fulltext Access 6 Pages 2017
A chemiluminescence sensor with signal amplification based on a self-immolative reaction for the detection of fluoride ion at low concentrations
Fulltext Access 6 Pages 2017
Design and properties of glutamic acid-based coumarin derivatives as organogelators
Fulltext Access 6 Pages 2017
Mesomeric betaines constructed of quinolinium cations and carboxylate anions separated by thiophene-ethynyl spacers as fluorescent dipoles
Fulltext Access 6 Pages 2017
Gold catalysis-facilitated rapid synthesis of the daphnane/tigliane tricyclic core
Fulltext Access 6 Pages 2017
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