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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Graphene oxide: A carbocatalyst for the one-pot multicomponent synthesis of highly functionalized tetrahydropyridines
Fulltext Access 5 Pages 2017
Molecular mobility in the supercooled and glassy states of nizatidine and perphenazine
Fulltext Access 5 Pages 2017
1er semestre 2017
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Empirical drug discovery: a view from the proteome
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The unique status of first-in-human studies: strengthening the social value requirement
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Darstellung stabiler 1,2-acetoxonium-salze acetylierter hexosen und pentosen
Fulltext Access 5 Pages 2017
meso-Tetraaryl-7,8-dihydroxydithiachlorins: first examples of heterochlorins
Fulltext Access 5 Pages 2017
Screening method for the evaluation of asymmetric catalysts for the reduction of aliphatic ketones
Fulltext Access 5 Pages 2017
Preparation of highly functionalized 1,5-disubstituted tetrazoles via palladium-catalyzed Suzuki coupling
Fulltext Access 5 Pages 2017
Harnessing open-source technology for low-cost automation in synthesis: Flow chemical deprotection of silyl ethers using a homemade autosampling system
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Purification of isopropyl fatty acids markedly changed the skin permeation of a model hydrophilic chemical
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Turn-on fluorescent detection of strong acids based on a naphthalimide-indoline hybrid
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A concise and efficient synthesis of tetrahydroquinoline alkaloids using the phase transfer mediated Wittig olefination reaction
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Synthesis and conformational study of triazole-linked bis-spirostanic conjugates
Fulltext Access 5 Pages 2017
Copper-catalyzed tandem reaction directed toward synthesis of 2,2-disubstituted quinazolinones from vinyl halides and 2-aminobenzamides
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Iron-mediated remote C-H bond benzylation of 8-aminoquinoline amides
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A simple and highly selective fluorescent sensor for palladium based on benzofuran-2-boronic acid
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An acrylated fullerene derivative for efficient and thermally stable polymer solar cells
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Dihydropyridazine-appended dibenzosuberenones as a new class of fluorophores: Application to fluoride sensing
Fulltext Access 5 Pages 2017
Synthesis of structure-defined branched hyaluronan tetrasaccharide glycoclusters
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Design, synthesis, and biological evaluation of pyrrolobenzodiazepine-containing hypoxia-activated prodrugs
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Artificial Intelligence Tools for Scaling Up of High Shear Wet Granulation Process
Fulltext Access 5 Pages 2017
Synthesis of Caffeine/Maleic Acid Co-crystal by Ultrasound-assisted Slurry Co-crystallization
Fulltext Access 5 Pages 2017
Effect of Temperature on the Kinetics of the Activation of Treosulfan and Hydrolytic Decomposition of Its Active Epoxy Derivatives
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Combined proportional and additive residual error models in population pharmacokinetic modelling
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An Opinion on non-human primates testing in Europe
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Selective synthesis of 2-aminobenzoxazoles and 2-mercaptobenzoxazoles by using o-aminophenols as starting material
Fulltext Access 5 Pages 2017
One-pot synthesis of vinylisoxazolidines from simple hydroxylamines and conjugated carbonyls
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Synthesis, characterization, photophysical properties and stability of bay-substituted tetrachloro-perylene diimide dianion salt by alkali treatment
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Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study
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Encapsulation of nano-catalysts in permeable silicone elastomers
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Antibacterial activities of viriditoxin congeners and synthetic analogues against fish pathogens
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Synergistic effects-Is it possible to make 'the devil an angel'?
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High altitude and pre-eclampsia: Adaptation or protection
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Dilated cardiomyopathy-induced disruption of basement membrane alters the lever systems acting on the heart
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Nanoparticle-loaded biodegradable light-responsive in situ forming injectable implants for effective peptide delivery to the posterior segment of the eye
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The role of soluble epoxide hydrolase in preeclampsia
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A proposal for a noninvasive monitoring of sympathetic nerve activity in patients with takotsubo syndrome
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Evaluation of lidocaine loaded clay based dermal patch systems
Fulltext Access 5 Pages 2017
The design, synthesis, and anti-inflammatory evaluation of a drug-like library based on the natural product valerenic acid
Fulltext Access 5 Pages 2017
Higher functionality of extracellular vesicles isolated using size-exclusion chromatography compared to ultracentrifugation
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Liposomal encapsulation masks genotoxicity of a chemotherapeutic agent in regulatory toxicology assessments
Fulltext Access 5 Pages 2017
Solvent free, fast and asymmetric Michael additions of ketones to nitroolefins using chiral pyrrolidine-pyridone conjugate bases as organocatalysts
Fulltext Access 5 Pages 2017
Design and synthesis of new triazoles linked to xanthotoxin for potent and highly selective anti-gastric cancer agents
Fulltext Access 5 Pages 2017
Original endomorphin-1 analogues exhibit good analgesic effects with minimal implications for human sperm motility
Fulltext Access 5 Pages 2017
Light induced drug release from a folic acid-drug conjugate
Fulltext Access 5 Pages 2017
Discovery of a potent angiotensin converting enzyme inhibitor via virtual screening
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Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - A novel class of compounds with potent activity against acute myeloid leukemia cells
Fulltext Access 5 Pages 2017
Synthesis and characterization of tetraoctyloxy substituted naphthalenophanedienes
Fulltext Access 5 Pages 2017
Introduction of fluorine to phenyl group of 4-(2-pyrimidinylamino)benzamides leading to a series of potent hedgehog signaling pathway inhibitors
Fulltext Access 5 Pages 2017
Synthesis and evaluation of hydroxychalcones as multifunctional non-purine xanthine oxidase inhibitors for the treatment of hyperuricemia
Fulltext Access 5 Pages 2017
Diarylpentadienone derivatives (curcumin analogues): Synthesis and anti-inflammatory activity
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Synthesis and biological activity of salinomycin-hydroxamic acid conjugates
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Phenylpropanoid glycosides from the roots of Jasminum giraldii
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Chiral pool based synthesis of pyrrolidinium ionic liquids
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Concise access to primin, miconidin and related natural resorcinols
Fulltext Access 5 Pages 2017
Enantioselective alkylation of aromatic aldehydes with (+)-camphoric acid derived chiral 1,3-diamine ligands
Fulltext Access 6 Pages 2017
Connecting the dots: Overlaps between autism and cancer suggest possible common mechanisms regarding signaling pathways related to metabolic alterations
Fulltext Access 6 Pages 2017
Lorenz system in the thermodynamic modelling of leukaemia malignancy
Fulltext Access 6 Pages 2017
Parkinson's disease; the hibernating spore hypothesis
Fulltext Access 6 Pages 2017
Synthesis and biological evaluation of the natural product komaroviquinone and related compounds aiming at a potential therapeutic lead compound for high-risk multiple myeloma
Fulltext Access 6 Pages 2017
The kynurenine pathway: Towards metabolic equilibrium
Fulltext Access 6 Pages 2017
Synthesis and characterization of novel flavonoid derivatives via sequential phosphorylation of quercetin
Fulltext Access 6 Pages 2017
Synthesis of polyhydroxylated bicyclic tetrahydrofurans and tetrahydropyrans via a stereoselective domino cyclization/reduction reaction
Fulltext Access 6 Pages 2017
Highly enantioselective asymmetric reactions involving zinc ions promoted by chiral aziridine alcohols
Fulltext Access 6 Pages 2017
A general approach to access 5,6-dihydroindolo-naphthyridine ring system
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Synthesis of new 3-cyanoacetamide pyrrole and 3-acetonitrile pyrrole derivatives
Fulltext Access 6 Pages 2017
Hypothesis: Co-transfer of genuine embryos and implantation-promoting compounds via artificial containers improve endometrium receptivity
Fulltext Access 6 Pages 2017
Synthesis of enantiopure cyclic amino acid derivatives via a sequential diastereoselective Petasis reaction/ring closing olefin metathesis process
Fulltext Access 6 Pages 2017
Graphical contents list
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Stereoselective Michael-alkylation and Michael-oxidation reactions of chiral 1,3-dioxolanones
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Synthesis of a novel sterically hindered chiral cyclic phosphoric acid derived from l-tartaric acid and application to the asymmetric catalytic Biginelli reaction
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Pharmacological and phytochemical studies of Alangium salvifolium Wang. - A review
Fulltext Access 6 Pages 2017
Application of membrane-selective electrodes for the determination of Tiemonium methylsulphate
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Water-acetic acid mediated chemoselective synthesis of pyrazolines via multimolecular domino reactions of enaminones and sulfonyl hydrazines
Fulltext Access 6 Pages 2017
Visualization of hybrid gold-loaded polymeric nanoparticles in cells using scanning electron microscopy
Fulltext Access 6 Pages 2017
Enzymatic kinetic resolution of Morita-Baylis-Hillman acetates
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Azo-pyrene-based fluorescent sensor of reductive cleavage of isomeric azo functional group
Fulltext Access 6 Pages 2017
Design, synthesis and biological evaluation of novel indolin-2-ones as potent anticancer compounds
Fulltext Access 6 Pages 2017
Sulfonylative alkoxyhydroxylation of 2-arylpropenes
Fulltext Access 6 Pages 2017
A rapid entry into thioflavanones via conjugate additions of diarylcuprates to thiochromones
Fulltext Access 6 Pages 2017
Synthesis and characterization of symmetrical sulfur-fused polycyclic aromatic hydrocarbons with controlled shapes
Fulltext Access 6 Pages 2017
Effect of directional migration on Lotka-Volterra system with desert
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Sustainable cooperation based on reputation and habituation in the public goods game
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On plant roots logical gates
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A new integrated symmetrical table for genetic codes
Fulltext Access 6 Pages 2017
Anti-influenza activity of monoterpene-containing substituted coumarins
Fulltext Access 6 Pages 2017
Graphical contents list
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Nonlinear relationship between enteric-coated mycophenolate sodium dose and mycophenolic acid exposure in Han kidney transplantation recipients
Fulltext Access 6 Pages 2017
A practical ortho-rearrangement of silyl group of ortho-bromophenyl silyl ethers using magnesium(0)
Fulltext Access 6 Pages 2017
Direct access to 1,4-benzothiazine 4,4-dioxides and 4-oxides via a domino reaction
Fulltext Access 6 Pages 2017
The influence of cetomacrogol ointment processing on structure: A definitive screening design
Fulltext Access 6 Pages 2017
Development of 5-hydroxypyrazole derivatives as reversible inhibitors of lysine specific demethylase 1
Fulltext Access 6 Pages 2017
A mild and one-step synthesis of 2,8-dioxabicyclo [3.3.1] nonane derivatives via classical Knoevenagel condensation
Fulltext Access 6 Pages 2017
Exploring the safety and clinical use of herbal medicine in the contemporary Ghanaian context: A descriptive qualitative study
Fulltext Access 6 Pages 2017
Design, synthesis, biological evaluation and molecular modelling studies of novel diaryl substituted pyrazolyl thiazolidinediones as potent pancreatic lipase inhibitors
Fulltext Access 6 Pages 2017
Sleep and cargo reorganization: A hypothesis
Fulltext Access 6 Pages 2017
An intramedullary nail coated with antibiotic and growth factor nanoparticles: An individualized state-of-the-art treatment for chronic osteomyelitis with bone defects
Fulltext Access 6 Pages 2017
Synthesis and biological evaluation of novel 1,2,3-triazole derivatives as anti-tubercular agents
Fulltext Access 6 Pages 2017
A chemiluminescence sensor with signal amplification based on a self-immolative reaction for the detection of fluoride ion at low concentrations
Fulltext Access 6 Pages 2017
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