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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Skin advanced glycation content reflects vaginal tissue glycation level in relation to pregnancy
Fulltext Access 4 Pages 2017
Silylated iminophosphonates: Novel reactive synthons for the preparation of fluorinated aminophosphonates and aminophosphonic acids
Fulltext Access 4 Pages 2017
Controlled hydrogenation of diphenylacetylene using alkylammonium formate
Fulltext Access 4 Pages 2017
Synthesis of polyunsaturated fatty acid-containing glucuronosyl-diacylglycerol through direct glycosylation
Fulltext Access 4 Pages 2017
Benzylic bromination catalyzed by triphenylphosphine selenide via Lewis basic activation
Fulltext Access 4 Pages 2017
Visible-light-promoted synthesis of diaryl sulfides under air
Fulltext Access 4 Pages 2017
Efficient colorimetric fluoride anion chemosensors based-on simple naphthodipyrrolidone dyes
Fulltext Access 4 Pages 2017
Base-catalyzed cross coupling of secondary alcohols and aryl-aldehydes with concomitant oxidation of alcohols to ketones: An alternative route for synthesis of the Claisen-Schmidt condensation products
Fulltext Access 4 Pages 2017
Fluoride anion-induced intramolecular cyclopropanation of allylsilanes
Fulltext Access 4 Pages 2017
Silica chloride: An efficient promoter for oxidation of arylboronic acids to phenols
Fulltext Access 4 Pages 2017
Targeting lipodisks enable selective delivery of anticancer peptides to tumor cells
Fulltext Access 4 Pages 2017
Palladium incorporated on carbonaceous catalyst for Suzuki coupling reaction in water
Fulltext Access 4 Pages 2017
A simple synthesis of choline alkyl phosphates
Fulltext Access 4 Pages 2017
An analysis of the diastereomeric transition state interactions for stereoselective epoxidation of acyclic allylic alcohols with peroxy-acids
Fulltext Access 4 Pages 2017
Physical stability of highly concentrated injectable drugs solutions used in intensive care units
Fulltext Access 4 Pages 2017
Synthesis of 2,3,6-trisubstituted pyridines by transition-metal free cyclization of 1,3-diynes with amino acids
Fulltext Access 4 Pages 2017
The neural signature of emotional memories in serial crimes
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Male contraception: Prospects for sound and ultrasound
Fulltext Access 4 Pages 2017
Horseradish and radish peroxidases eaten with fish could help explain observed associations between fish consumption and protection from age-related dementia
Fulltext Access 4 Pages 2017
Polycystic ovary syndrome in men
Fulltext Access 4 Pages 2017
Worn is born: The role of the maxillo-mandibular relation in management of worn dentition
Fulltext Access 4 Pages 2017
Cannabinoids: Possible agents for treatment of psoriasis via suppression of angiogenesis and inflammation
Fulltext Access 4 Pages 2017
Heart rate variability regression and risk of sudden unexpected death in epilepsy
Fulltext Access 4 Pages 2017
Potential relationship between periodontal diseases and eye diseases
Fulltext Access 4 Pages 2017
Continuous-flow synthesis using a column reactor packed with heterogeneous catalysts: A convenient production of nitroolefins by using amino-functionalized silicagel
Fulltext Access 4 Pages 2017
gem-Dithioacetylated indole derivatives as novel antileishmanial agents
Fulltext Access 4 Pages 2017
Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides
Fulltext Access 4 Pages 2017
Measles: What we have learned from non-human primate models
Fulltext Access 4 Pages 2017
Specific inhibitory effects of myricetin on human proton-coupled folate transporter: Comparison with its effects on rat proton-coupled folate transporter and human riboflavin transporter 3
Fulltext Access 4 Pages 2017
Short CommunicationHuman brain endothelial barrier cells are distinctly less vulnerable to silver nanoparticles toxicity than human blood vessel cells: A cell-specific mechanism of the brain barrier?
Fulltext Access 4 Pages 2017
Copalic acid analogs down-regulate androgen receptor and inhibit small chaperone protein
Fulltext Access 4 Pages 2017
Efficient synthesis of a multi-substituted diphenylmethane skeleton as a steroid mimetic
Fulltext Access 4 Pages 2017
An expedient synthesis of resveratrol through a highly recoverable palladium catalyst
Fulltext Access 4 Pages 2017
Cytotoxic and anti-oxidant biphenyl derivatives from the leaves and twigs of Garcinia multiflora
Fulltext Access 4 Pages 2017
One-pot two-step facile synthesis of 2,3,4,5-tetra substituted dihydrooxazoles and their antimicrobial activity
Fulltext Access 4 Pages 2017
Evaluation of tetraether lipid-based liposomal carriers for encapsulation and retention of nucleoside-based drugs
Fulltext Access 4 Pages 2017
Two new benzoyl glucuronosyl glycerols from the leaves of Garcinia buchananii Baker
Fulltext Access 4 Pages 2017
Perfusion computed tomography imaging of abdominal aortic aneurysms may be of value for patient specific rupture risk estimation
Fulltext Access 5 Pages 2017
Potent and selective oxytocin receptor agonists without disulfide bridges
Fulltext Access 5 Pages 2017
Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a vascular endothelial growth factor inhibitor
Fulltext Access 5 Pages 2017
A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group
Fulltext Access 5 Pages 2017
High altitude and pre-eclampsia: Adaptation or protection
Fulltext Access 5 Pages 2017
Calcium-channel blockers as therapeutic agents for acquired sensorineural hearing loss
Fulltext Access 5 Pages 2017
Intra-spinal microstimulation may alleviate chronic pain after spinal cord injury
Fulltext Access 5 Pages 2017
Boron - A potential goiterogen?
Fulltext Access 5 Pages 2017
Bottom-up gamma and stages of waking
Fulltext Access 5 Pages 2017
Biological functions of melatonin in relation to pathogenesis of oral lichen planus
Fulltext Access 5 Pages 2017
Heterogeneity of hypoxia in solid tumours and mechanochemical reactions with oxygen nanobubbles
Fulltext Access 5 Pages 2017
Interconvertible geometric isomers of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors exhibit multiple binding modes
Fulltext Access 5 Pages 2017
Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - A novel class of compounds with potent activity against acute myeloid leukemia cells
Fulltext Access 5 Pages 2017
The effects of foot reflexology on anxiety and physiological parameters among candidates for bronchoscopy: A randomized controlled trial
Fulltext Access 5 Pages 2017
Fermi-Pasta-Ulam auto recurrence in the description of the electrical activity of the heart
Fulltext Access 5 Pages 2017
Hypocapnic hypothesis of Leigh disease
Fulltext Access 5 Pages 2017
Hypothesis: A perfect day conveys internal time
Fulltext Access 5 Pages 2017
Does complement Factor H-Related protein 5 Nephropathy (Troodos Nephropathy) protect from rickettsial infections?
Fulltext Access 5 Pages 2017
Synthesis and evaluation of the anti-proliferative activity of diaryl-3-pyrrolin-2-ones and fused analogs
Fulltext Access 5 Pages 2017
A new dawn in cannabinoid neurobiology: The road from molecules to therapeutic discoveries
Fulltext Access 5 Pages 2017
A fast, new method to enhance the enantiomeric purity of non-racemic mixtures: self-disproportionation of enantiomers in the gas antisolvent fractionation of chlorine-substituted mandelic acid derivatives
Fulltext Access 5 Pages 2017
Original endomorphin-1 analogues exhibit good analgesic effects with minimal implications for human sperm motility
Fulltext Access 5 Pages 2017
Identification of a diverse synthetic abietane diterpenoid library and insight into the structure-activity relationships for antibacterial activity
Fulltext Access 5 Pages 2017
Direct observation of positive supercoils introduced by reverse gyrase through atomic force microscopy
Fulltext Access 5 Pages 2017
Silver-catalyzed diastereo- and enantioselective Michael additions of 2-oxazoline- and 2-thiazoline-4-carboxylate to nitroalkenes
Fulltext Access 5 Pages 2017
An Opinion on non-human primates testing in Europe
Fulltext Access 5 Pages 2017
Graphical contents list
Fulltext Access 5 Pages 2017
Enhancement of antibacterial activity of ciprofloxacin hydrochloride by complexation with sodium cholate
Fulltext Access 5 Pages 2017
Improved predictions of nonlinear support vector regression and artificial neural network models via preprocessing of data with orthogonal projection to latent structures: A case study
Fulltext Access 5 Pages 2017
Impact of pharmacist-led collaborative patient education on medication adherence and quality of life of schizophrenia patients in a tertiary care setting
Fulltext Access 5 Pages 2017
Expanded aromatic carboxylate anion induced molecular sandwich construction via a tetracationic imidazolium macrocycle conversion from molecular box to molecular tweezer
Fulltext Access 5 Pages 2017
Synthesis of functionalized chromene and spirochromenes using l-proline-melamine as highly efficient and recyclable homogeneous catalyst at room temperature
Fulltext Access 5 Pages 2017
A concise and efficient synthesis of tetrahydroquinoline alkaloids using the phase transfer mediated Wittig olefination reaction
Fulltext Access 5 Pages 2017
Solid-phase supported nitrosocarbonyl intermediates: Old scope and new limitations in the organic synthesis
Fulltext Access 5 Pages 2017
Synthesis and conformational study of triazole-linked bis-spirostanic conjugates
Fulltext Access 5 Pages 2017
New cyclen-cored dendrimers functionalized with pyrene: Synthesis characterization, optical and photophysical properties
Fulltext Access 5 Pages 2017
Mercuration of calix[4]arenes immobilized in the 1,2- and 1,3-alternate conformations
Fulltext Access 5 Pages 2017
Tandem and chemoselective synthesis of benzil derivatives from styrene and arene diazonium salts
Fulltext Access 5 Pages 2017
Biomimetic total synthesis and structure confirmation of myrtucommulone K
Fulltext Access 5 Pages 2017
Electrochemical bromination of late stage intermediates and drug molecules
Fulltext Access 5 Pages 2017
Inverse thermoresponse of a water-soluble helicene oligomer in aqueous-organic mixed solvent systems
Fulltext Access 5 Pages 2017
Silver-catalyzed chemoselective annulation of propargyl amines with alkynes for access to pyridines and pyrroles
Fulltext Access 5 Pages 2017
A four-blade light-driven plastic mill based on hydrazone liquid-crystal networks
Fulltext Access 5 Pages 2017
Ester hydrolysis: Conditions for acid autocatalysis and a kinetic switch
Fulltext Access 5 Pages 2017
A functional applied material on recognition of metal ion zinc based on the double azine compound
Fulltext Access 5 Pages 2017
Boron trifluoride facilitated transesterification of dioxaborolanes
Fulltext Access 5 Pages 2017
An expeditious synthetic protocol for chlorination of imidazole N-oxide: Synthesis of 2-chloroimidazoles
Fulltext Access 5 Pages 2017
Synthesis of isoflavene-thiosemicarbazone hybrids and evaluation of their anti-tumor activity
Fulltext Access 5 Pages 2017
Diarylpentadienone derivatives (curcumin analogues): Synthesis and anti-inflammatory activity
Fulltext Access 5 Pages 2017
An unexpected course of a palladium catalyzed three-component reaction leading to steroid chroman ketals
Fulltext Access 5 Pages 2017
A borondipyrrolemethene-based turn-on fluorescent probe for silver ion with high sensitivity and selectivity and its application in water samples and living cells
Fulltext Access 5 Pages 2017
Turn-on fluorescent detection of strong acids based on a naphthalimide-indoline hybrid
Fulltext Access 5 Pages 2017
Direct palladium-catalyzed allylic alkylations of alcohols with enamines: Synthesis of homoallyl ketones
Fulltext Access 5 Pages 2017
Encapsulation of nano-catalysts in permeable silicone elastomers
Fulltext Access 5 Pages 2017
Graphene oxide: A carbocatalyst for the one-pot multicomponent synthesis of highly functionalized tetrahydropyridines
Fulltext Access 5 Pages 2017
Harnessing open-source technology for low-cost automation in synthesis: Flow chemical deprotection of silyl ethers using a homemade autosampling system
Fulltext Access 5 Pages 2017
Synthesis and antimicrobial evaluation of cationic low molecular weight amphipathic 1,2,3-triazoles
Fulltext Access 5 Pages 2017
Antitubulin effects of aminobenzothiophene-substituted triethylated chromones
Fulltext Access 5 Pages 2017
Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators
Fulltext Access 5 Pages 2017
The unique status of first-in-human studies: strengthening the social value requirement
Fulltext Access 5 Pages 2017
Empirical drug discovery: a view from the proteome
Fulltext Access 5 Pages 2017
Palladium-catalyzed direct arylation of maleimides: A simple route to bisaryl-substituted maleimides
Fulltext Access 5 Pages 2017
Effects of auricular acupressure therapy for preventing constipation in leukemia patients undergoing chemotherapy: Protocol for a systematic review
Fulltext Access 5 Pages 2017
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