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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Ultrasound-enhanced penetration through sclera depends on frequency of sonication and size of macromolecules
Fulltext Access 7 Pages 2017
Piezoelectric material - A promising approach for bone and cartilage regeneration
Fulltext Access 7 Pages 2017
Neonatal and regressive forms of autism: Diseases with similar symptoms but a different etiology
Fulltext Access 7 Pages 2017
Fast and effective photodynamic inactivation of 4-day-old biofilm of methicillin-resistant Staphylococcus aureus using methylene blue-conjugated gold nanoparticles
Fulltext Access 7 Pages 2017
Brain delivery of baclofen as a hydrophilic drug by nanolipid carriers: Characteristics and pharmacokinetics evaluation
Fulltext Access 7 Pages 2017
Ultrasound triggered drug delivery for mitochondria targeted sonodynamic therapy
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Development and evaluation of a polyvinyl alcohol based topical gel
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Investigation of tannic acid cross-linked onto magnetite nanoparticles for applying in drug delivery systems
Fulltext Access 7 Pages 2017
Valsartan floating bioadhesive compression-coated mini-tablets: Formulation and pharmacokinetics
Fulltext Access 7 Pages 2017
Assessing the performance of copaiba oil and allantoin nanoparticles on multidrug-resistant Candida parapsilosis
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Development of respirable rifampicin-loaded nano-lipomer composites by microemulsion-spray drying for pulmonary delivery
Fulltext Access 7 Pages 2017
Diversity selection, screening and quantitative structure-activity relationships of osmolyte-like additive effects on the thermal stability of a monoclonal antibody
Fulltext Access 7 Pages 2017
Single jugular vein cannulated rats may not be suitable for intravenous pharmacokinetic screening of high logP compounds
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Tumor-associated immune aggregates in oral cancer: Their cellular composition and potential prognostic significance
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One should avoid retro-orbital pharmacokinetic sample collections for intranasal dosing in rats: Illustration of spurious pharmacokinetics generated for anti-migraine drugs zolmitriptan and eletriptan
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Development of a solid dosage platform for the oral delivery of bilayer vesicles
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Effect of cyclophosphamide on the solid form of mannitol during lyophilization
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In vitro simulation of realistic gastric pressure profiles
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Melanin binding study of clinical drugs with cassette dosing and rapid equilibrium dialysis inserts
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Adverse drug reactions in Korean herbal medicine: A prospective cohort study
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Acute effects of physical exercise with microcurrent in the adipose tissue of the abdominal region: A randomized controlled trial
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A Summary of a Cochrane Review: Yoga treatment for chronic non-specific low back pain
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Clinical effectiveness of the Sanfu herbal patch at acupoints for respiratory diseases including otitis media in children: A pilot before-and-after study
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Effects of tai chi on symptoms and quality of life in women with overactive bladder symptoms: A non-randomized clinical trial
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Animal-assisted therapy used for anxiety disorders in patients with learning disabilities: An observational study
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Reactive group-embedded affinity labeling reagent for efficient intracellular protein labeling
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Large animal models to test mechanical circulatory support devices
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Models for evaluating the immune response to naturally derived biomaterials
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Human Tissue Distribution of Carbonyl Reductase 1 Using Proteomic Approach With Liquid Chromatography-Tandem Mass Spectrometry
Fulltext Access 7 Pages 2017
Bulky Polar Additives That Greatly Reduce the Viscosity of Concentrated Solutions of Therapeutic Monoclonal Antibodies
Fulltext Access 7 Pages 2017
An Education Strategy to Respond to Medicine Inequality in Africa
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The indications of tautomeric conversion in amorphous bicalutamide drug
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Non-human primate models and in vitro liver stage cultures as alternatives in malaria drug development
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Recent applications of gold-catalyzed cascade reactions in total synthesis of natural product
Fulltext Access 7 Pages 2017
Synthesis and reactivity of new amide-substituted oxindole derivatives
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Effects of core moiety and substituted positions in phenothiazine-based hole transporting materials towards high thermal stability and good hole mobility
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Contents of macro-, microelements and long-lived radionuclides in the medicinal plants belonging to the wetland community of Siberian region, Russia
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Beta-glucans and cancer: The influence of inflammation and gut peptide
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Effect of short-term hand reflexology on anxiety in patients before coronary angiography: A randomized placebo controlled trial
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Design, synthesis and bioactivities of Celecoxib analogues or derivatives
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Some experimental aspects of absolute configuration determination using single crystal X-ray diffraction
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Best practice and pitfalls in absolute structure determination
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Single particle extinction and scattering optical method unveils in real time the influence of the blood components on polymeric nanoparticles
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The use of heparin in infertility and recurrent pregnancy loss: Are its antiviral properties at play?
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Is small intestinal bacterial overgrowth involved in the pathogenesis of functional dyspepsia?
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Knowledge about dietary fibre and its health benefits: A cross-sectional survey of 2536 residents from across Croatia
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Use of anthropogenic nitrogen fertilizers in agriculture is associated with per capita ethanol consumption
Fulltext Access 7 Pages 2017
How extreme dieting becomes compulsive: A novel hypothesis for the role of anxiety in the development and maintenance of anorexia nervosa
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Phosphodiesterases and preeclampsia
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Is damage to the pre-frontal cortex dormant until adolescence, or difficult to detect? Looking for keys that unlock executive functions in children in the wrong place
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Graphical contents list
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The first one-pot ambient-temperature synthesis of 1,2,4-oxadiazoles from amidoximes and carboxylic acid esters
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One-pot synthesis of novel fused pentacyclic chromenopyrimidobenzimidazolones and benzimidazolyl-chromenyl-substituted thiazolidinones
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Rational design of first generation inhibitors for trehalose 6-phosphate phosphatases
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Copper-catalyzed methylation of 1,3-diketones with tert-butyl peroxybenzoate
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Exploratory spectroscopic and computational studies of the anion binding properties of methyl hyocholate in organic solvent
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Lanostane-type triterpenoids from Kadsura coccinea
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Grinding assisted, column chromatography free decarboxylative carbon-carbon bond formation: Greener synthesis of 3, 3-disubstituted oxindoles
Fulltext Access 7 Pages 2017
Novel quinoxaline derivative: Solubilization by surfactant solutions and membranotropic properties
Fulltext Access 7 Pages 2017
Practical, efficient, and broadly applicable synthesis of readily differentiable vicinal diboronate compounds by catalytic three-component reactions
Fulltext Access 7 Pages 2017
A facile method to enable a model phospholipid cell-permeable and photoactivatable
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Exploration of the influence of spiro-dienone moiety on biological activity of the cytotoxic marine alkaloid discorhabdin P
Fulltext Access 7 Pages 2017
Palladium-catalyzed regio- and chemoselective direct desulfitative arylation of anilides with arylsulfonyl chlorides
Fulltext Access 7 Pages 2017
A versatile approach to hybrid thiadiazine-based molecules by the Ugi four-component reaction
Fulltext Access 7 Pages 2017
Design and expeditious synthesis of organosilanes as potent antivirals targeting multidrug-resistant influenza A viruses
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Synthesis of new morpholine-connected pyrazolidine derivatives and their antimicrobial, antioxidant, and cytotoxic activities
Fulltext Access 7 Pages 2017
Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors
Fulltext Access 7 Pages 2017
Synthesis of novel steroidal agonists, partial agonists, and antagonists for the glucocorticoid receptor
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Efficient synthesis of novel dialkyl-3-cyanopropylphosphate derivatives and evaluation of their anticholinesterase activity
Fulltext Access 7 Pages 2017
Synthesis of novel fenfuram-diarylether hybrids as potent succinate dehydrogenase inhibitors
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Long-term release of antibiotics by carbon nanotube-coated titanium alloy surfaces diminish biofilm formation by Staphylococcus epidermidis
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Gold nanorods reflectance discriminate benign from malignant oral lesions
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Quality-by-design of nanopharmaceuticals - a state of the art
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Enhanced efficacy of combination heat shock targeted polymer therapeutics with high intensity focused ultrasound
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The nanomechanical role of melanin granules in the retinal pigment epithelium
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Transition-metal-free regioselective thiocyanation of phenols, anilines and heterocycles
Fulltext Access 7 Pages 2017
Identification of novel glutathione adducts of benzbromarone in human liver microsomes
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Arterial relaxation is coupled to inhibition of mitochondrial fission in arterial smooth muscle cells: comparison of vasorelaxant effects of verapamil and phentolamine
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Preparation and evaluation of rhenium-188-pamidronate as a palliative treatment in bone metastasis
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Neutron-activatable radionuclide cancer therapy using graphene oxide nanoplatelets
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Monitoring of macrophage accumulation in statin-treated atherosclerotic mouse model using sodium iodide symporter imaging system
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The evolution of library design: crafting smart compound collections for phenotypic screens
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The living organism: Strengthening the basis
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A one-pot, multi-component reaction cascade for the rapid synthesis of diversely functionalized heteroaryl methyl substrates
Fulltext Access 7 Pages 2017
One-pot preparation of pyrrole derivatives via the copper-catalyzed [4+1] annulation of propargylic amines with ethyl glyoxylate and phenylglyoxal in the presence of piperidine
Fulltext Access 7 Pages 2017
Practical synthesis of bicyclic pyrazol-5-one derivatives
Fulltext Access 7 Pages 2017
The colorimetric and ratiometric fluorescent detection of cyanide and sulfide in live cells, application for logic gate and bioimging
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A mild copper catalyzed method for the selective deprotection of aryl allyl ethers
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A specific spectral signature of serum and plasma-derived extracellular vesicles for cancer screening
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A formal synthesis of (+/-) parvifoline by an aromatic Cope rearrangement of a trans-1-aryl-2-ethenylcyclobutanecarbonitrile
Fulltext Access 7 Pages 2017
Copper-catalyzed synthesis of 2-sulfenylindoles from indoline-2-thiones and aryl iodides
Fulltext Access 7 Pages 2017
Visible-light-induced perfluoroalkylation/arylmigration/desulfonylation cascades of conjugated tosyl amides
Fulltext Access 7 Pages 2017
A cinnamoyl substituted Nile Red-based probe to detect hydrazine
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Synthesis of polysubstituted 5-hydroxyhydantoins via ring-opening of isatins
Fulltext Access 7 Pages 2017
Hexafluoro-2-propanol-assisted quick and chemoselective nitro reduction using iron powder as catalyst under mild conditions
Fulltext Access 7 Pages 2017
Synthesis and device properties of carbazole/benzimidazole-based host materials
Fulltext Access 7 Pages 2017
Immobilization of palladium nanoparticles on ionic liquid-triethylammonium chloride functionalized magnetic nanoparticles: As a magnetically separable, stable and recyclable catalyst for Suzuki-Miyaura cross-coupling reactions
Fulltext Access 7 Pages 2017
Straightforward synthesis of novel substituted 1,3,4-thiadiazole derivatives in choline chloride-based deep eutectic solvent
Fulltext Access 7 Pages 2017
Nickel-catalyzed decarboxylative coupling of an alkynyl carboxylic acid with aryl iodides
Fulltext Access 7 Pages 2017
Rapid aerobic iodination of arenes mediated by hypervalent iodine in fluorinated solvents
Fulltext Access 7 Pages 2017
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