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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Silk fibroin degumming affects scaffold structure and release of macromolecular drugs
Fulltext Access 8 Pages 2017
Combination of grape extract-silver nanoparticles and liposomes: A totally green approach
Fulltext Access 8 Pages 2017
Intranasal delivery of ciprofloxacin to rats: A topical approach using a thermoreversible in situ gel
Fulltext Access 8 Pages 2017
Mesoporous silica nanoparticles as a new carrier methodology in the controlled release of the active components in a polypill
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Nanoformulation of dual bexarotene-tailed phospholipid conjugate with high drug loading
Fulltext Access 8 Pages 2017
An innovative polysaccharide nanobased nail formulation for improvement of onychomycosis treatment
Fulltext Access 8 Pages 2017
A calix[4]arene derivative and its selective interaction with drugs (clofibric acid, diclofenac and aspirin)
Fulltext Access 8 Pages 2017
Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery
Fulltext Access 8 Pages 2017
An innovative method for preparation of hydrophobic ion-pairing colistin entrapped poly(lactic acid) nanoparticles: Loading and release mechanism study
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Pharmacokinetic drug-drug interaction between erlotinib and paracetamol: A potential risk for clinical practice
Fulltext Access 8 Pages 2017
Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms
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In vivo analysis of supersaturation/precipitation/absorption behavior after oral administration of pioglitazone hydrochloride salt; determinant site of oral absorption
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Comparison of liposomal drug formulations for transdermal iontophoretic drug delivery
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Pharmacokinetic analysis of modified-release metoprolol formulations: An interspecies comparison
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Evaluation of the cytotoxicity and intestinal absorption of a self-emulsifying drug delivery system containing sodium taurocholate
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Imidazole-4-acetic acid, a new lead structure for interaction with the taurine transporter in outer blood-retinal barrier cells
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Molecular insights into the formation of drug-monoacyl phosphatidylcholine solid dispersions for oral delivery
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Increased drug load and polymer compatibility of bilayered orodispersible films
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Disposition of treosulfan and its active monoepoxide in a bone marrow, liver, lungs, brain, and muscle: Studies in a rat model with clinical relevance
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Positive messages may reduce patient pain: A meta-analysis
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Effects of aroma mouthwash on stress level, xerostomia, and halitosis in healthy nurses: A non-randomized controlled clinical trial
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Patient health literacy and patient-physician communication regarding complementary and alternative medicine usage
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Selecting diagnostic parameters of functional dyspepsia based on pattern identification: Step 1-Systematic literature review and expert consensus process
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Depressed patients' experiences with and perspectives on treatment provided by homeopaths. A qualitative interview study embedded in a trial
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The effects of aromatherapy essential oil inhalation on stress, sleep quality and immunity in healthy adults: Randomized controlled trial
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Stereospecific inhibition of nitric oxide production in macrophage cells by flavanonols: Synthesis and the structure-activity relationship. Part 2
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Computational Dehydration of Crystalline Hydrates Using Molecular Dynamics Simulations
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Mechanism and Kinetics of Punch Sticking of Pharmaceuticals
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Dissolution Methods to Increasing Discriminatory Power of In Vitro Dissolution Testing for Ibuprofen Free Acid and Its Salts
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Investigating Intra-Tablet Coating Uniformity With Spectral-Domain Optical Coherence Tomography
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Topical immunization using a nanoemulsion containing bacterial membrane antigens
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Graphical abstract contents listing
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In vivo evaluation of supersaturation/precipitation/re-dissolution behavior of cinnarizine, a lipophilic weak base, in the gastrointestinal tract: the key process of oral absorption
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Synthesis, characterization and liver targeting evaluation of self-assembled hyaluronic acid nanoparticles functionalized with glycyrrhetinic acid
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Model-based clinical dose optimization for phenobarbital in neonates: An illustration of the importance of data sharing and external validation
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Therapeutic activity of superoxide dismutase-containing enzymosomes on rat liver ischaemia-reperfusion injury followed by magnetic resonance microscopy
Fulltext Access 8 Pages 2017
Utility of picric acid and 2,4 dinitrophenol as chromogenic reagents for visible spectrophotometric quantification of alogliptin
Fulltext Access 8 Pages 2017
Structural coverage of the proteome for pharmaceutical applications
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Evidences for salbutamol metabolism by respiratory and liver cell lines
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Anti-tuberculosis activity and structure-activity relationships of oxygenated tricyclic carbazole alkaloids and synthetic derivatives
Fulltext Access 8 Pages 2017
Identification of nitroimidazole-oxime derivatives targeting the polo-box domain of polo-like kinase 1
Fulltext Access 8 Pages 2017
Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Fulltext Access 8 Pages 2017
Cortical and amygdalar neuronal ensembles in alcohol seeking, drinking and withdrawal
Fulltext Access 8 Pages 2017
Cognitive eloquence in neurosurgery: Insight from graph theoretical analysis of complex brain networks
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Multiple sclerosis and air pollution exposure: Mechanisms toward brain autoimmunity
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Fabrication of functionalized porous silica nanoparticles and their controlled release behavior
Fulltext Access 8 Pages 2017
Carrageenan-stabilized chitosan alginate nanoparticles loaded with ethionamide for the treatment of tuberculosis
Fulltext Access 8 Pages 2017
Influence of state and crystallinity of lipid matrix on physicochemical properties and permeation of capsaicin-loaded lipid nanoparticles for topical delivery
Fulltext Access 8 Pages 2017
A targeted drug delivery system of anti-cancer agents based on folic acid-cyclodextrin-long polymer functionalized silica nanoparticles
Fulltext Access 8 Pages 2017
Successful co-encapsulation of benzoyl peroxide and chloramphenicol in liposomes by a novel manufacturing method - dual asymmetric centrifugation
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Design and synthesis of 1,2,3-triazolo-phenanthrene hybrids as cytotoxic agents
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Synthesis of asymmetrically disubstituted anthracenes
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The application of a specific morphinan template to the synthesis of galanthamine
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Selected latest applications of molecular spectroscopy in natural product analysis
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Bioactivity-guided mixed synthesis accelerate the serendipity in lead optimization: Discovery of fungicidal homodrimanyl amides
Fulltext Access 8 Pages 2017
Design, synthesis and antimicrobial evaluation of novel benzoxazole derivatives
Fulltext Access 8 Pages 2017
Graphical contents list
Fulltext Access 8 Pages 2017
Graphical contents list
Fulltext Access 8 Pages 2017
Synthesis and formulation studies of griseofulvin analogues with improved solubility and metabolic stability
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Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives
Fulltext Access 8 Pages 2017
The evaluation of 1,4-benzoquinones as inhibitors of human monoamine oxidase
Fulltext Access 8 Pages 2017
Recent progress in prodrug design strategies based on generally applicable modifications
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Photo-controlled release of fipronil from a coumarin triggered precursor
Fulltext Access 8 Pages 2017
Regioselective bromination: Synthesis of brominated methoxyquinolines
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Functional evaluation of synthetic flavonoids and chalcones for potential antiviral and anticancer properties
Fulltext Access 8 Pages 2017
Influence of the cellular environment on ligand binding kinetics at membrane-bound targets
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Amine promiscuity and toxicology analysis
Fulltext Access 8 Pages 2017
Synthesis and biological evaluation of 2-alkoxycarbonylallyl esters as potential anticancer agents
Fulltext Access 8 Pages 2017
Synthesis of alpha amylase inhibitors based on privileged indole scaffold
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Fatty-monastrol derivatives and its cytotoxic effect against melanoma cell growth
Fulltext Access 8 Pages 2017
Synthesis and biological evaluation of quinazolinone-based hydrazones with potential use in Alzheimer's disease
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Chiral thiophosphoramide catalyzed asymmetric aryl transfer reactions for the synthesis of functional diarylmethanols
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Tumor accumulation of liposomal doxorubicin in three murine models: Optimizing delivery efficiency
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Peptide amphiphile nanofiber hydrogel delivery of sonic hedgehog protein to the cavernous nerve to promote regeneration and prevent erectile dysfunction
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Identification of potential inhibitors against the Zika virus using consensus scoring
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Efficient synthesis of isoindoles using supercritical carbon dioxide
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Les principaux antiseptiques
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Asiatic acid inhibits lung cancer cell growth in vitro and in vivo by destroying mitochondria
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Establishment of a new acute-on-chronic liver failure model
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Effect of methoxy group position on biological properties of 18F-labeled benzyl triphenylphosphonium cations
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Phenotypic screening-the fast track to novel antibody discovery
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Optimism in the face of uncertainty supported by a statistically-designed multi-armed bandit algorithm
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An efficient synthesis of substituted chrysenes
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Copper promoted desulfurization towards the synthesis of isothiocyanates
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Preparation of isoindolinones via a palladium-catalyzed diamination
Fulltext Access 8 Pages 2017
Reductive carboxylation of aromatic esters by electron transfer from magnesium metal
Fulltext Access 8 Pages 2017
Construction of bicyclic systems containing an oxygen bridge by isomerization of cyclic epoxy alcohols
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Construction of chiral 3,3-disubstituted oxindoles by a thiourea-catalyzed substitution of phenylsulfonyl with 2-naphthol
Fulltext Access 8 Pages 2017
An Improved Methodology for Multidimensional High-Throughput Preformulation Characterization of Protein Conformational Stability
Fulltext Access 8 Pages 2017
Synthesis and properties of a thiophene-substituted diaza[7]helicene for application as a blue emitter in organic light-emitting diodes
Fulltext Access 8 Pages 2017
Solid-phase synthesis for novel nerve agent adducted nonapeptides as biomarkers
Fulltext Access 8 Pages 2017
Convenient one-pot synthesis of thiobarbituro-quinoline derivatives via catalyst-free multicomponent reactions in water
Fulltext Access 8 Pages 2017
Synthesis and application in photovoltaic device of the porphyrin derivatives with liquid crystal properties
Fulltext Access 8 Pages 2017
Solvent-free enantioselective conjugate addition and bioactivities of nitromethane to Chalcone containing pyridine
Fulltext Access 8 Pages 2017
Protonation behavior of thiaporphyrin and thiabenzoporphyrin
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Synthesis of 3-oxadiazolyl/triazolyl morpholines: Novel scaffolds for drug discovery
Fulltext Access 8 Pages 2017
Anion receptors based on intramolecularly bridged calix[4]arenes bearing ureido functions
Fulltext Access 8 Pages 2017
Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis(indolyl)methanes
Fulltext Access 8 Pages 2017
Construction and single crystal structures of pseudo[1]rotaxanes based on pillar[5]arene mono-pyridylimine derivatives
Fulltext Access 8 Pages 2017
Synthesis of multiply arylated pyridines
Fulltext Access 8 Pages 2017
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