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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Phenotypic chemical biology for predicting safety and efficacy
Fulltext Access 8 Pages 2017
Preparation of dual responsive low-molecular-weight hydrogel for long-lasting drug delivery
Fulltext Access 8 Pages 2017
Stereospecific inhibition of nitric oxide production in macrophage cells by flavanonols: Synthesis and the structure-activity relationship. Part 2
Fulltext Access 8 Pages 2017
Effect of replacing main-chain ureas with thiourea and guanidinium surrogates on the bactericidal activity of membrane active oligourea foldamers
Fulltext Access 8 Pages 2017
Construction of bicyclic systems containing an oxygen bridge by isomerization of cyclic epoxy alcohols
Fulltext Access 8 Pages 2017
Synthesis of a library of glucal-derived triazoles via copper-catalyzed azide-alkyne cyclization
Fulltext Access 8 Pages 2017
Reductive carboxylation of aromatic esters by electron transfer from magnesium metal
Fulltext Access 8 Pages 2017
Cinnabarinic acid and xanthurenic acid: Two kynurenine metabolites that interact with metabotropic glutamate receptors
Fulltext Access 8 Pages 2017
Emission pathway switching by solvent polarity: Facile synthesis of benzofuran-bipyridine derivatives and turn-on fluorescence probe for zinc ions
Fulltext Access 8 Pages 2017
Copper promoted desulfurization towards the synthesis of isothiocyanates
Fulltext Access 8 Pages 2017
An efficient synthesis of substituted chrysenes
Fulltext Access 8 Pages 2017
ReviewPost-screenHow can nanoparticles contribute to antituberculosis therapy?
Fulltext Access 8 Pages 2017
Gastric bypass surgery mimetic approaches
Fulltext Access 8 Pages 2017
Synthesis of 2-aryl quinazolines from (2-aminophenyl)methanol and oxime ether catalyzed by copper ferrite nanoparticles
Fulltext Access 8 Pages 2017
Phenotypic screening-the fast track to novel antibody discovery
Fulltext Access 8 Pages 2017
Implementation of flu vaccination in community pharmacies: Understanding the barriers and enablers
Fulltext Access 8 Pages 2017
Evidences for salbutamol metabolism by respiratory and liver cell lines
Fulltext Access 8 Pages 2017
Subchronic vortioxetine treatment -but not escitalopram- enhances pyramidal neuron activity in the rat prefrontal cortex
Fulltext Access 8 Pages 2017
Carrageenan-stabilized chitosan alginate nanoparticles loaded with ethionamide for the treatment of tuberculosis
Fulltext Access 8 Pages 2017
Disposition of treosulfan and its active monoepoxide in a bone marrow, liver, lungs, brain, and muscle: Studies in a rat model with clinical relevance
Fulltext Access 8 Pages 2017
Influence of state and crystallinity of lipid matrix on physicochemical properties and permeation of capsaicin-loaded lipid nanoparticles for topical delivery
Fulltext Access 8 Pages 2017
Electronic drug delivery systems: An overview
Fulltext Access 8 Pages 2017
Phospholipid-drug conjugates as a novel oral drug targeting approach for the treatment of inflammatory bowel disease
Fulltext Access 8 Pages 2017
An innovative polysaccharide nanobased nail formulation for improvement of onychomycosis treatment
Fulltext Access 8 Pages 2017
Comparison of liposomal drug formulations for transdermal iontophoretic drug delivery
Fulltext Access 8 Pages 2017
Silk fibroin degumming affects scaffold structure and release of macromolecular drugs
Fulltext Access 8 Pages 2017
Graphical contents list
Fulltext Access 8 Pages 2017
Tumor accumulation of liposomal doxorubicin in three murine models: Optimizing delivery efficiency
Fulltext Access 8 Pages 2017
Peptide amphiphile nanofiber hydrogel delivery of sonic hedgehog protein to the cavernous nerve to promote regeneration and prevent erectile dysfunction
Fulltext Access 8 Pages 2017
Influence of the cellular environment on ligand binding kinetics at membrane-bound targets
Fulltext Access 8 Pages 2017
Photo-controlled release of fipronil from a coumarin triggered precursor
Fulltext Access 8 Pages 2017
Topical immunization using a nanoemulsion containing bacterial membrane antigens
Fulltext Access 8 Pages 2017
Pharmaceutical applications of lectins
Fulltext Access 8 Pages 2017
In situ targeted activation of an anticancer agent using ultrasound-triggered release of composite droplets
Fulltext Access 8 Pages 2017
Graphical contents list
Fulltext Access 8 Pages 2017
Software based approaches for drug designing and development: A systematic review on commonly used software and its applications
Fulltext Access 8 Pages 2017
Use of carbon-11 labelled tool compounds in support of drug development
Fulltext Access 8 Pages 2017
Design, synthesis and antimicrobial evaluation of novel benzoxazole derivatives
Fulltext Access 8 Pages 2017
Recent advances in activatable fluorescence imaging probes for tumor imaging
Fulltext Access 8 Pages 2017
Non-human primates are essential models in the translational research of multiple sclerosis
Fulltext Access 8 Pages 2017
Selected latest applications of molecular spectroscopy in natural product analysis
Fulltext Access 8 Pages 2017
Regioselective bromination: Synthesis of brominated methoxyquinolines
Fulltext Access 8 Pages 2017
Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors
Fulltext Access 9 Pages 2017
Design and synthesis of novel photoinduced electron transfer-based hybridization probes
Fulltext Access 9 Pages 2017
Non-Sink Dissolution Behavior and Solubility Limit of Commercial Tacrolimus Amorphous Formulations
Fulltext Access 9 Pages 2017
A Comparison of Aerosolization and Homogenization Techniques for Production of Alginate Microparticles for Delivery of Corticosteroids to the Colon
Fulltext Access 9 Pages 2017
Three-Dimensional Printing of Medicinal Products and the Challenge of Personalized Therapy
Fulltext Access 9 Pages 2017
Rapid loading and prolonged release of latanoprost from a silicone hydrogel contact lens
Fulltext Access 9 Pages 2017
Synthesis of 3-acyl, methylene and epoxy substituted isoindolinone derivatives via the ortho-lithiation/cyclization procedures of aromatic imines with carbon monoxide
Fulltext Access 9 Pages 2017
Paclitaxel Encapsulated in Halloysite Clay Nanotubes for Intestinal and Intracellular Delivery
Fulltext Access 9 Pages 2017
Synthesis, characterization and cellular cytotoxicity evaluation of a new magnetic nanoparticle carrier co-functionalized with amine and folic acid
Fulltext Access 9 Pages 2017
In vitro cytotoxic, antibacterial, anti-inflammatory and antioxidant activities and phenolic content in wild-grown flowers of common daisy-A medicinal plant
Fulltext Access 9 Pages 2017
The hormonal sensitivity hypothesis: A review and new findings
Fulltext Access 9 Pages 2017
Animal models of cardiovascular disease as test beds of bioengineered vascular grafts
Fulltext Access 9 Pages 2017
Metal-free one-pot synthesis of benzofurans with ynones and quinones through aza-Michael/Michael/annulation sequence
Fulltext Access 9 Pages 2017
An automated method by which effects of compounds on locomotor activity and spontaneous neuropathic pain-specific movements can be simultaneously evaluated in rats with chronic-constriction nerve injury
Fulltext Access 9 Pages 2017
Development of biodegradable polyesters with various microstructures for highly controlled release of epirubicin and cyclophosphamide
Fulltext Access 9 Pages 2017
Solid effervescent formulations as new approach for topical minoxidil delivery
Fulltext Access 9 Pages 2017
Enhancing polo-like kinase 1 selectivity of polo-box domain-binding peptides
Fulltext Access 9 Pages 2017
Formulation design and optimization of novel fast dissolving tablet of chlorpheniramine maleate by using lyophilization techniques
Fulltext Access 9 Pages 2017
Reagent-free continuous thermal tert-butyl ester deprotection
Fulltext Access 9 Pages 2017
Verification study for an empirical rule in diverse helical conformational behaviors of asymmetric 1,2-diacyl-sn-glycerols in the solution state
Fulltext Access 9 Pages 2017
Synthesis and in vitro biological evaluation of novel quinazoline derivatives
Fulltext Access 9 Pages 2017
Iron-catalyzed selective oxidative arylation of phenols and biphenols
Fulltext Access 9 Pages 2017
Scalable synthesis of enaminones utilizing Gold's reagents
Fulltext Access 9 Pages 2017
Reinvestigation of synthesis of halo-substituted 3-phenyl-1-(2-pyridyl)-2-propen-1-ones (azachalcones). A tandem reaction for formation of penta-substituted cyclohexanols
Fulltext Access 9 Pages 2017
Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties
Fulltext Access 9 Pages 2017
Recent developments of coumarin-containing derivatives and their anti-tubercular activity
Fulltext Access 9 Pages 2017
Synthesis and bioactivity investigation of quinone-based dimeric cationic triazolium amphiphiles selective against resistant fungal and bacterial pathogens
Fulltext Access 9 Pages 2017
Structural optimization elaborates novel potent Akt inhibitors with promising anticancer activity
Fulltext Access 9 Pages 2017
Rhodamine B conjugates of triterpenoic acids are cytotoxic mitocans even at nanomolar concentrations
Fulltext Access 9 Pages 2017
Synthesis and antimalarial evaluation of artesunate-polyamine and trioxolane-polyamine conjugates
Fulltext Access 9 Pages 2017
An efficient artificial molecular pump
Fulltext Access 9 Pages 2017
The discovery of fluazaindolizine: A new product for the control of plant parasitic nematodes
Fulltext Access 9 Pages 2017
Novel benzimidazolyl tetrahydroprotoberberines: Design, synthesis, antimicrobial evaluation and multi-targeting exploration
Fulltext Access 9 Pages 2017
Expanding the tetrahydroquinoline pharmacophore
Fulltext Access 9 Pages 2017
Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors
Fulltext Access 9 Pages 2017
Bifunctional bisphosphonate derivatives and platinum complexes with high affinity for bone hydroxyapatite
Fulltext Access 9 Pages 2017
Cytotoxic effects of a novel maleimide derivative on epithelial and tumor cells
Fulltext Access 9 Pages 2017
Synthesis and preliminary biological assay of uridine glycoconjugate derivatives containing amide and/or 1,2,3-triazole linkers
Fulltext Access 9 Pages 2017
Protective effects of hepatocyte-specific glycyrrhetic derivatives against carbon tetrachloride-induced liver damage in mice
Fulltext Access 9 Pages 2017
What can acupuncture bring to Western medicine? The perspective of health professionals also trained in Traditional Chinese Medicine-based acupuncture
Fulltext Access 9 Pages 2017
Diabetes development increased concentrations of the conjugated bile acid, taurocholic acid in serum, while treatment with microencapsulated-taurocholic acid exerted no hypoglycaemic effects
Fulltext Access 9 Pages 2017
Encapsulation, controlled release, and antitumor efficacy of cisplatin delivered in liposomes composed of sterol-modified phospholipids
Fulltext Access 9 Pages 2017
Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy
Fulltext Access 9 Pages 2017
Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems
Fulltext Access 9 Pages 2017
Fluoride loaded polymeric nanoparticles for dental delivery
Fulltext Access 9 Pages 2017
The influence of mannitol on morphology and disintegration of spray-dried nano-embedded microparticles
Fulltext Access 9 Pages 2017
Cocrystal formation, crystal structure, solubility and permeability studies for novel 1,2,4-thiadiazole derivative as a potent neuroprotector
Fulltext Access 9 Pages 2017
Exploring the current working profiles of nutritional therapists to inform curriculum and professional development
Fulltext Access 9 Pages 2017
The benefit/risk balance of subcutaneous injections as used in homeopathy and anthroposophic medicine: A narrative literature review
Fulltext Access 9 Pages 2017
Assessing the stable conformations of ibuprofen in solution by means of Residual Dipolar Couplings
Fulltext Access 9 Pages 2017
Generation of human pluripotent stem cell-derived hepatocyte-like cells for drug toxicity screening
Fulltext Access 9 Pages 2017
Regioselective and efficient halogenation of 4,5-unsubstituted alkyl 3-hydroxypyrrole/3-hydroxythiophene-2-yl-carboxylates
Fulltext Access 9 Pages 2017
Sulfated polyborate: An efficient and reusable catalyst for one pot synthesis of Hantzsch 1,4-dihydropyridines derivatives using ammonium carbonate under solvent free conditions
Fulltext Access 9 Pages 2017
Synthesis of substituted benzofurans and indoles by Zn-catalyzed tandem Sonogashira-cyclization strategy
Fulltext Access 9 Pages 2017
Two unusual isoflavonoids from Campylotropis hirtella - A new biosynthesis route of flavonoids
Fulltext Access 9 Pages 2017
Synthesis of olefins via a Wittig reaction mediated by triphenylarsine
Fulltext Access 9 Pages 2017
Synthesis of monovinyl- and divinyl-chlorophyll analogs and their physical properties
Fulltext Access 9 Pages 2017
An efficient, scalable approach to hydrolyze flavonoid glucuronides via activation of glycoside bond
Fulltext Access 9 Pages 2017
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