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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Clinical practice guidelines for the use of traditional Korean medicine in the treatment of patients with traffic-related injuries: An evidence-based approach
Fulltext Access 8 Pages 2018
Development and evaluation of terbutaline sulfate orally disintegrating tablets by direct compression and freeze drying methods
Fulltext Access 8 Pages 2018
Use of cassava starch nanocrystals to make a robust rupturable pulsatile release pellet
Fulltext Access 8 Pages 2018
The effect of formulation additives on in vitro dissolution-absorption profile and in vivo bioavailability of telmisartan from brand and generic formulations
Fulltext Access 8 Pages 2018
Dexamethasone palmitate large porous particles: A controlled release formulation for lung delivery of corticosteroids
Fulltext Access 8 Pages 2018
Mechanism of the formation of hollow spherical granules using a high shear granulator
Fulltext Access 8 Pages 2018
Personalisation of warfarin therapy using thermal ink-jet printing
Fulltext Access 8 Pages 2018
The use of molecular descriptors in the development of co-amorphous formulations
Fulltext Access 8 Pages 2018
Application of composite dissolving microneedles with high drug loading ratio for rapid local anesthesia
Fulltext Access 8 Pages 2018
Mesoporous silica nanoparticles facilitating the dissolution of poorly soluble drugs in orodispersible films
Fulltext Access 8 Pages 2018
The effect of size and polymer architecture of doxorubicin-poly(ethylene) glycol conjugate nanocarriers on breast duct retention, potency and toxicity
Fulltext Access 8 Pages 2018
Chemical cross-linking: A feasible approach to prolong doxylamine/pyridoxine release from spray-dried chitosan microspheres
Fulltext Access 8 Pages 2018
Novel dry powder inhaler formulation containing antibiotic using combined technology to improve aerodynamic properties
Fulltext Access 8 Pages 2018
Self-assembled cyclodextrin-based nanoparticles for meropenem stabilization
Fulltext Access 8 Pages 2018
Development and delivery of an evidence-based medicine programme for Traditional Chinese Medicine students using an international collaborative approach: An action research project
Fulltext Access 8 Pages 2018
The effects of fertility-supporting health training on healthy lifestyle behaviors and infertility self-efficacy in infertile women: A quasi-experimental study
Fulltext Access 8 Pages 2018
Adjunctive moxibustion treatment for tuberculosis: A randomised clinical trial investigating potential efficacy and comparative safety
Fulltext Access 8 Pages 2018
Teaching midwives homeopathy-A Belgian pilot project
Fulltext Access 8 Pages 2018
Quantitative analysis of elevation of serum creatinine via renal transporter inhibition by trimethoprim in healthy subjects using physiologically-based pharmacokinetic model
Fulltext Access 8 Pages 2018
Anti-hyperglycaemic activity of tuber extract of Chlorophytum alismifolium Baker in streptozotocin-induced hyperglycaemic rats
Fulltext Access 8 Pages 2018
In vitro permeation and stability studies on developed drug-in-adhesive transdermal patch of simvastatin
Fulltext Access 8 Pages 2018
One-pot synthesis and biodistribution of fluorine-18 labeled serum albumin for vascular imaging
Fulltext Access 8 Pages 2018
Brief overview of solubility methods: Recent trends in equilibrium solubility measurement and predictive models
Fulltext Access 8 Pages 2018
Recent advances in bacteriophage-based methods for bacteria detection
Fulltext Access 8 Pages 2018
Cochlear hair cell regeneration: an emerging opportunity to cure noise-induced sensorineural hearing loss
Fulltext Access 8 Pages 2018
Selection of Solid-State Plasticizers as Processing Aids for Hot-Melt Extrusion
Fulltext Access 8 Pages 2018
Enhanced anticancer effect of Brucea javanica oil by solidified self-microemulsifying drug delivery system
Fulltext Access 8 Pages 2018
Synchronizing the release rates of salicylate and indomethacin from degradable chitosan hydrogel and its optimization by definitive screening design
Fulltext Access 8 Pages 2018
Next-generation sequencing in drug development: target identification and genetically stratified clinical trials
Fulltext Access 8 Pages 2018
Hydrogen bonding network assisted regio- and stereo- controlled hydrohalogenations of sulfonyl alkynes
Fulltext Access 8 Pages 2018
Preparation and Evaluation of Multifunctional Autofluorescent Magnetic Nanoparticle-Based Drug Delivery Systems Against Mammary Cancer
Fulltext Access 8 Pages 2018
Pharmacokinetics and Preventive Effects of Sulfo-Albumin as a Novel Macromolecular Hydrogen Sulfide Prodrug on Carbon Tetrachloride-Induced Hepatic Injury
Fulltext Access 8 Pages 2018
Design, synthesis and biological evaluation of lazabemide derivatives as inhibitors of monoamine oxidase
Fulltext Access 8 Pages 2018
Synthesis and evaluation of an orally available “Y”-shaped biaryl peroxisome proliferator-activated receptor δ agonist
Fulltext Access 8 Pages 2018
Novel synthesis of 5-iodo-1,2,3-triazoles using an aqueous iodination system under air
Fulltext Access 8 Pages 2018
Tautomerism of protonated imidazoles: A perspective from ab initio valence bond theory
Fulltext Access 8 Pages 2018
The potential for disease initiation by inhaled beta-emitting nuclear particles
Fulltext Access 8 Pages 2018
'Give-up-itis' revisited: Neuropathology of extremis
Fulltext Access 8 Pages 2018
Extension of quality-by-design concept to the early development phase of pharmaceutical R&D processes
Fulltext Access 8 Pages 2018
Understanding Protein-Interface Interactions of a Fusion Protein at Silicone Oil-Water Interface Probed by Sum Frequency Generation Vibrational Spectroscopy
Fulltext Access 8 Pages 2018
Composite Alginate-Hyaluronan Sponges for the Delivery of Tranexamic Acid in Postextractive Alveolar Wounds
Fulltext Access 8 Pages 2018
Prediction of Apparent Oral Clearance of Small-Molecule Inhibitors in Pediatric Patients
Fulltext Access 8 Pages 2018
Environmentally Responsive Dual-Targeting Nanoparticles: Improving Drug Accumulation in Cancer Cells as a Way of Preventing Anticancer Drug Efflux
Fulltext Access 8 Pages 2018
Can the Cellular Internalization of Cargo Proteins Be Enhanced by Fusing a Tat Peptide in the Center of Proteins? A Fluorescence Study
Fulltext Access 8 Pages 2018
Thermodynamic Estimate of the Number of Solvent Molecules Displaced by a Solute Molecule for Enthalpy-Driven Adsorption: Phenobarbital and Activated Carbons as the Model System
Fulltext Access 8 Pages 2018
Bile Acid as an Effective Absorption Enhancer for Oral Delivery of Epidermal Growth Factor Receptor-Targeted Hybrid Peptide
Fulltext Access 8 Pages 2018
Spectral Reflectance Measurement of Evaporating Chemical Films: Initial Results and Application to Skin Permeation
Fulltext Access 8 Pages 2018
Evaluation of Using Dogs to Predict Fraction of Oral Dose Absorbed in Humans for Poorly Water-Soluble Drugs
Fulltext Access 8 Pages 2018
High-Throughput In-Use and Stress Size Stability Screening of Protein Therapeutics Using Algorithm-Driven Dynamic Light Scattering
Fulltext Access 8 Pages 2018
Development of a promising drug delivery for formononetin: Cyclodextrin-modified single-walled carbon nanotubes
Fulltext Access 8 Pages 2018
Thiazole-substituted benzenesulfonamides as inhibitors of 12 human carbonic anhydrases
Fulltext Access 8 Pages 2018
Novel fluconazole derivatives with promising antifungal activity
Fulltext Access 8 Pages 2018
Fine-tuning the physicochemical properties of peptide-based blood-brain barrier shuttles
Fulltext Access 8 Pages 2018
Unprecedented sugar bridged bisindoles selective inhibiting glioma stem cells
Fulltext Access 8 Pages 2018
Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides
Fulltext Access 8 Pages 2018
Cell penetrating peptides to dissect host-pathogen protein-protein interactions in Theileria-transformed leukocytes
Fulltext Access 8 Pages 2018
Design, synthesis and biological evaluation of novel hydroxamic acid based histone deacetylase 6 selective inhibitors bearing phenylpyrazol scaffold as surface recognition motif
Fulltext Access 8 Pages 2018
Design, synthesis and biological evaluation of novel hydrogen sulfide releasing capsaicin derivatives
Fulltext Access 8 Pages 2018
An opportunistic route to success: Towards a change of paradigm to fully exploit the potential of cell-penetrating peptides
Fulltext Access 8 Pages 2018
Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists
Fulltext Access 8 Pages 2018
Antiplasmodial activity of hydroxyethylamine analogs: Synthesis, biological activity and structure activity relationship of plasmepsin inhibitors
Fulltext Access 8 Pages 2018
The synthesis and evaluation of phenoxyacylhydroxamic acids as potential agents for Helicobacter pylori infections
Fulltext Access 8 Pages 2018
Synthesis and antitumor activity of bis(hydroxymethyl)propionate analogs of pterostilbene in cisplatin-resistant human oral cancer cells
Fulltext Access 8 Pages 2018
Inducing protein-protein interactions with molecular glues
Fulltext Access 8 Pages 2018
Synthesis, molecular modelling and biological evaluation of tetrasubstituted thiazoles towards cholinesterase enzymes and cytotoxicity studies
Fulltext Access 8 Pages 2018
Multi-targetable chalcone analogs to treat deadly Alzheimer's disease: Current view and upcoming advice
Fulltext Access 8 Pages 2018
Design, synthesis and antiplasmodial activity of novel imidazole derivatives based on 7-chloro-4-aminoquinoline
Fulltext Access 8 Pages 2018
Supramolecular nanofibers self-assembled from cationic small molecules derived from repurposed poly(ethylene teraphthalate) for antibiotic delivery
Fulltext Access 8 Pages 2018
Adsorption behaviors of supercritical Lennard-Jones fluid in slit-like pores
Fulltext Access 8 Pages 2018
Tailoring antibiotic release for the treatment of periodontal infrabony defects using bioactive gelatin-alginate/apatite nanocomposite films
Fulltext Access 8 Pages 2018
A new mathematical approach to predict the actual drug release from hydrogels
Fulltext Access 8 Pages 2018
Studying of drug solubility in water and alcohols using drug-ammonium ionic liquid-compounds
Fulltext Access 8 Pages 2018
Preparation and characterization of intravaginal vardenafil suppositories targeting a complementary treatment to boost in vitro fertilization process
Fulltext Access 8 Pages 2018
The quest for exceptional drug solubilization in diluted surfactant solutions and consideration of residual solid state
Fulltext Access 8 Pages 2018
Mucoadhesive maleimide-functionalised liposomes for drug delivery to urinary bladder
Fulltext Access 8 Pages 2018
Process design methodology for organometallic chemistry in continuous flow systems
Fulltext Access 8 Pages 2018
Two-photon fluorescent probe for hydrogen sulfide based on a red-emitting benzocoumarin dye
Fulltext Access 8 Pages 2018
Recent topics in dual hydrogen bonding catalysis
Fulltext Access 8 Pages 2018
Radical reactions of aryl alkynoates in organic synthesis: Recent advances
Fulltext Access 8 Pages 2018
Expansion of the aromatic part of Cinchona alkaloids. Annulation of quinolines with phenoxazine motifs
Fulltext Access 8 Pages 2018
Synthesis and evaluation of simplified functionalized bongkrekic acid analogs
Fulltext Access 8 Pages 2018
The synthesis of the molecular chaperone 2,5-dideoxy-2,5-imino-d-altritol via diastereoselective reductive amination and carbamate annulation
Fulltext Access 8 Pages 2018
Palladium-catalyzed oxamidation of alkenes: A new approach to benzoxazolidines
Fulltext Access 8 Pages 2018
Synthetic studies on a series of functionalized pyrylium salts, 4-chloro- and 4-bromophosphinines
Fulltext Access 8 Pages 2018
Inclusion complexation of a deep cavitand with imidazoquinoxaline flaps forming stable vase-like conformation
Fulltext Access 8 Pages 2018
Anionic N-heterocyclic carbenes by decarboxylation of sydnone-4-carboxylates
Fulltext Access 8 Pages 2018
Aerobic intramolecular aminothiocyanation of unactivated alkenes promoted by in situ generated iodine thiocyanate
Fulltext Access 8 Pages 2018
Synthesis of apocarotenoids by acyclic cross metathesis and characterization as substrates for human retinaldehyde dehydrogenases
Fulltext Access 8 Pages 2018
New mesalamine polymeric conjugate for controlled release: Preparation, characterization and biodistribution study
Fulltext Access 8 Pages 2018
Selective formation of heteroaryl thioethers via a phosphonium ion coupling reaction
Fulltext Access 8 Pages 2018
Highly efficient construction of chiral dispirocyclic oxindole/thiobutyrolactam/chromanone complexes through Michael/cyclization cascade reactions with a rosin-based squaramide catalyst
Fulltext Access 8 Pages 2018
Optimization of 2-alkoxyacetates as acylating agent for enzymatic kinetic resolution of chiral amines
Fulltext Access 8 Pages 2018
Synthesis of carboxylated chlorophyll derivatives and their activities in dye-sensitized solar cells
Fulltext Access 8 Pages 2018
Iodine-promoted five-component reaction using fragment assembly strategy to construct dihydrooxepines
Fulltext Access 8 Pages 2018
Efficient synthesis of tetrazole derivatives of cytisine using the azido-Ugi reaction
Fulltext Access 8 Pages 2018
Non-destructive quality assessment of herbal tea blends using hyperspectral imaging
Fulltext Access 8 Pages 2018
Resolvins as proresolving inflammatory mediators in cardiovascular disease
Fulltext Access 8 Pages 2018
Synthesis and antiplasmodial activity of glyco-conjugate hybrids of phenylhydrazono-indolinones and glycosylated 1,2,3-triazolyl-methyl-indoline-2,3-diones
Fulltext Access 8 Pages 2018
Recent encounters with atropisomerism in drug discovery
Fulltext Access 8 Pages 2018
Semisynthesis, cytotoxicity, antimalarial evaluation and structure-activity relationship of two series of triterpene derivatives
Fulltext Access 8 Pages 2018
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