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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

A novel quantified bitterness evaluation model for traditional Chinese herbs based on an animal ethology principle
Fulltext Access 9 Pages 2018
Cross-linked, cyclodextrin-based nanosponges for curcumin delivery - Physicochemical characterization, drug release, stability and cytotoxicity
Fulltext Access 9 Pages 2018
Antimicrobial in-situ forming gels based on bleached shellac and different solvents
Fulltext Access 9 Pages 2018
Layer-by-layer polyelectrolyte coating of alginate microgels for sustained release of sodium benzoate and zosteric acid
Fulltext Access 9 Pages 2018
Liposomes assembled from dimeric retinoic acid phospholipid with improved pharmacokinetic properties
Fulltext Access 9 Pages 2018
Dissolving polyvinylpyrrolidone-based microneedle systems for in-vitro delivery of sumatriptan succinate
Fulltext Access 9 Pages 2018
Relationship between exposure to treosulfan and its monoepoxytransformer - An insight from population pharmacokinetic study in pediatric patients before hematopoietic stem cell transplantation
Fulltext Access 9 Pages 2018
Study on the dissolution improvement of albendazole using reconstitutable dry nanosuspension formulation
Fulltext Access 9 Pages 2018
Total hepatocellular disposition profiling of rosuvastatin and pitavastatin in sandwich-cultured human hepatocytes
Fulltext Access 9 Pages 2018
Microfluidic Approaches for the Characterization of Therapeutic Proteins
Fulltext Access 9 Pages 2018
Rare genetic diseases: update on diagnosis, treatment and online resources
Fulltext Access 9 Pages 2018
Fishing anti(lymph)angiogenic drugs with zebrafish
Fulltext Access 9 Pages 2018
Cell membrane-coated nanocarriers: the emerging targeted delivery system for cancer theranostics
Fulltext Access 9 Pages 2018
Recent advances on catalytic asymmetric difunctionalization of 1,3-dienes
Fulltext Access 9 Pages 2018
Recent developments on artificial switchable catalysis
Fulltext Access 9 Pages 2018
Recent advances on nonenzymatic catalytic kinetic resolution of diols
Fulltext Access 9 Pages 2018
Asymmetric induction in photocatalysis - Discovering a new side to light-driven chemistry
Fulltext Access 9 Pages 2018
Photocatalytic alkoxy radical-mediated transformations
Fulltext Access 9 Pages 2018
Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?
Fulltext Access 9 Pages 2018
Phytantriol-based lyotropic liquid crystal as a transdermal delivery system
Fulltext Access 9 Pages 2018
Ruthenium-catalyzed annulation of aromatic ketones with internal alkynes: A reliable route to substituted naphthalene derivatives
Fulltext Access 9 Pages 2018
Discovery of novel cathepsin inhibitors with potent anti-metastatic effects in breast cancer cells
Fulltext Access 9 Pages 2018
Methoxycamalexins and related compounds: Syntheses, antifungal activity and inhibition of brassinin oxidase
Fulltext Access 9 Pages 2018
Bifunctional iminophosphorane superbases: Potent organocatalysts for enantio- and diastereoselective Michael addition reactions
Fulltext Access 9 Pages 2018
Ortho-lithiation reaction of aryl triflones
Fulltext Access 9 Pages 2018
Cranberry anthocyanin as an herbal medicine lowers plasma cholesterol by increasing excretion of fecal sterols
Fulltext Access 9 Pages 2018
Coupling corticotropin-releasing-hormone and angiotensin converting enzyme 2 dampens stress responsiveness in male mice
Fulltext Access 9 Pages 2018
Rapid discrimination and quantification analysis of five antineoplastic drugs in aqueous solutions using Raman spectroscopy
Fulltext Access 9 Pages 2018
A new etiologic model for Alzheimers Disease
Fulltext Access 9 Pages 2018
Male pattern hair loss: Taking one for the team: The selfless gene
Fulltext Access 9 Pages 2018
Autologous white blood cell infusion for trauma, brain trauma, stroke and select immune dysfunction co-morbidities: A promising and timely proposal?
Fulltext Access 9 Pages 2018
How chronic administration of benzodiazepines leads to unexplained chronic illnesses: A hypothesis
Fulltext Access 9 Pages 2018
Urinary tract infection's etiopathogenic role in nephrolithiasis formation
Fulltext Access 9 Pages 2018
A Mathematical Model and Experimental Verification of Optimal Nozzle Diameter in Needle-Free Injection
Fulltext Access 9 Pages 2018
Flow Microscopy Imaging Is Sensitive to Characteristics of Subvisible Particles in Peginesatide Formulations Associated With Severe Adverse Reactions
Fulltext Access 9 Pages 2018
Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease
Fulltext Access 9 Pages 2018
Fungal synthesis of chiral phosphonic synthetic platform - Scope and limitations of the method
Fulltext Access 9 Pages 2018
Synthesis, biological evaluation and molecular docking studies of a new series of chalcones containing naphthalene moiety as anticancer agents
Fulltext Access 9 Pages 2018
Efficiency of newly prepared thiazole derivatives against some cutaneous fungi
Fulltext Access 9 Pages 2018
Design and synthesis of pyrazolopyridine derivatives as sphingosine 1-phosphate receptor 2 ligands
Fulltext Access 9 Pages 2018
Design, synthesis and biological evaluation of phosphopeptides as Polo-like kinase 1 Polo-box domain inhibitors
Fulltext Access 9 Pages 2018
Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin
Fulltext Access 9 Pages 2018
Design, synthesis, characterization, antimicrobial evaluation and molecular modeling studies of some dehydroacetic acid-chalcone-1,2,3-triazole hybrids
Fulltext Access 9 Pages 2018
In-vitro evaluation of antioxidant, anti-elastase, anti-collagenase, anti-hyaluronidase activities of safranal and determination of its sun protection factor in skin photoaging
Fulltext Access 9 Pages 2018
Synthesis, biological evaluation and molecular modeling of novel thienopyrimidinone and triazolothienopyrimidinone derivatives as dual anti-inflammatory antimicrobial agents
Fulltext Access 9 Pages 2018
Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids
Fulltext Access 9 Pages 2018
Design, synthesis and biological evaluation of novel 1,3,4-trisubstituted pyrazole derivatives as potential chemotherapeutic agents for hepatocellular carcinoma
Fulltext Access 9 Pages 2018
Identification of cytotoxic, glutathione-reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion
Fulltext Access 9 Pages 2018
Molecular dynamics simulation of vibrational behavior of annular graphene sheet: Identification of nonlocal parameter
Fulltext Access 9 Pages 2018
Reaction profiling of a set of acrylamide-based human tissue transglutaminase inhibitors
Fulltext Access 9 Pages 2018
Tuning the rheological properties of an ammonium methacrylate copolymer for the design of adhesives suitable for transdermal patches
Fulltext Access 9 Pages 2018
Benzoxazine derivatives of phytophenols show anti-plasmodial activity via sodium homeostasis disruption
Fulltext Access 9 Pages 2018
Design, synthesis and biological evaluation of spiropyrimidinetriones oxazolidinone derivatives as antibacterial agents
Fulltext Access 9 Pages 2018
Mucoadhesive nanostructured polyelectrolytes complexes modulate the intestinal permeability of methotrexate
Fulltext Access 10 Pages 2018
A cross-sectional comparison between the perception of physicians and pharmacists concerning the role of the pharmacist in physician training
Fulltext Access 10 Pages 2018
Difference in substrate specificity of carboxylesterase and arylacetamide deacetylase between dogs and humans
Fulltext Access 10 Pages 2018
Evaluation of a Biologic Formulation Using Customized Design of Experiment and Novel Multidimensional Robustness Diagrams
Fulltext Access 10 Pages 2018
The Application of 3D Printing in the Formulation of Multilayered Fast Dissolving Oral Films
Fulltext Access 10 Pages 2018
Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1
Fulltext Access 10 Pages 2018
Enhanced neural stem cell functions in conductive annealed carbon nanofibrous scaffolds with electrical stimulation
Fulltext Access 10 Pages 2018
Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2
Fulltext Access 10 Pages 2018
Postulating the major environmental condition resulting in the expression of essential hypertension and its associated cardiovascular diseases: Dietary imprudence in daily selection of foods in respect of their potassium and sodium content resulting in ox
Fulltext Access 10 Pages 2018
Theoretical study on crystal morphologies of 1,1-diamino-2,2-dinitroethene in solvents: Modified attachment energy model and occupancy model
Fulltext Access 10 Pages 2018
Mechanistic studies of hydrogen-peroxide-mediated anthocyanin oxidation
Fulltext Access 10 Pages 2018
A bi-directional model of exercise and episodic memory function
Fulltext Access 10 Pages 2018
An antimycobacterial pleuromutilin analogue effective against dormant bacilli
Fulltext Access 10 Pages 2018
Chemoenzymatic synthesis of new derivatives of glycyrrhetinic acid with antiviral activity. Molecular docking study
Fulltext Access 10 Pages 2018
Developing precision medicine using scarless genome editing of human pluripotent stem cells
Fulltext Access 10 Pages 2018
Novel carbamate derivatives as selective butyrylcholinesterase inhibitors
Fulltext Access 10 Pages 2018
Transdermal formulation of 4-benzylpiperidine for cocaine-use disorder
Fulltext Access 10 Pages 2018
Statistical investigation of the full concentration range of fasted and fed simulated intestinal fluid on the equilibrium solubility of oral drugs
Fulltext Access 10 Pages 2018
An evaluation of neonicotinoids' potential to inhibit human cholinesterases: Protein-ligand docking and interaction profiling studies
Fulltext Access 10 Pages 2018
Does high pressure have any effect on the structure of alpha amylase and its ability to binding to the oligosaccharides having 3-7 residues? Molecular dynamics study
Fulltext Access 10 Pages 2018
Circulatory-cell-mediated nanotherapeutic approaches in disease targeting
Fulltext Access 10 Pages 2018
Breakthroughs in neuroactive steroid drug discovery
Fulltext Access 10 Pages 2018
Picolyl amides of betulinic acid as antitumor agents causing tumor cell apoptosis
Fulltext Access 10 Pages 2018
Contents (graphical abstracts and research highlights)
Fulltext Access 10 Pages 2018
Recent developments in non-enzymatic catalytic oxidative kinetic resolution of secondary alcohols
Fulltext Access 10 Pages 2018
Polygodial: A viable natural product scaffold for the rapid synthesis of novel polycyclic pyrrole and pyrrolidine derivatives
Fulltext Access 10 Pages 2018
Purposeful regioselectivity control of the Birch reductive alkylation of biphenyl-4-carbonitrile
Fulltext Access 10 Pages 2018
An overview of the total synthesis of africane-type sesquiterpenoids
Fulltext Access 10 Pages 2018
Transition-metal-catalyzed cyclization reactions using vinyl and ethynyl benzoxazinones as dipole precursors
Fulltext Access 10 Pages 2018
Site selectivities in fluorination
Fulltext Access 10 Pages 2018
Design, synthesis and pharmacological evaluation of some novel indanone derivatives as acetylcholinesterase inhibitors for the management of cognitive dysfunction
Fulltext Access 10 Pages 2018
One-step synthesis of carbohydrate esters as antibacterial and antifungal agents
Fulltext Access 10 Pages 2018
Discovery of new thienopyrimidine derivatives as potent and orally efficacious phosphoinositide 3-kinase inhibitors
Fulltext Access 10 Pages 2018
Amino acid content of beta strands and alpha helices depends on their flanking secondary structure elements
Fulltext Access 10 Pages 2018
Nanoparticles of Combretum quadrangulare leaf extract induce cytotoxicity, apoptosis, cell cycle arrest and anti-migration in lung cancer cells
Fulltext Access 10 Pages 2018
Synthesis and evaluation of novel dolastatin 10 derivatives for versatile conjugations
Fulltext Access 10 Pages 2018
Matrix systems for oral drug delivery: Formulations and drug release
Fulltext Access 10 Pages 2018
Peptide therapeutics for the treatment of gastrointestinal disorders
Fulltext Access 10 Pages 2018
Attitudes and beliefs that affect adherence to provider-based complementary and alternative medicine: A systematic review
Fulltext Access 10 Pages 2018
Traditional acupuncture for menopausal hot flashes: A systematic review and meta-analysis of randomized controlled trials
Fulltext Access 10 Pages 2018
Seek & Destroy, use of targeting peptides for cancer detection and drug delivery
Fulltext Access 10 Pages 2018
Dissolving polymeric microneedle arrays for enhanced site-specific acyclovir delivery
Fulltext Access 10 Pages 2018
Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylase
Fulltext Access 10 Pages 2018
Cosmetic and pharmaceutical qualifications of Egyptian bentonite and its suitability as drug carrier for Praziquantel drug
Fulltext Access 10 Pages 2018
Alginate as a potential diphase solid dispersion carrier with enhanced drug dissolution and improved storage stability
Fulltext Access 10 Pages 2018
Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells
Fulltext Access 10 Pages 2018
Design, synthesis, and biological evaluation of novel substituted benzamide derivatives bearing a 1,2,3-triazole moiety as potent human dihydroorotate dehydrogenase inhibitors
Fulltext Access 10 Pages 2018
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