Evaluation of a Biologic Formulation Using Customized Design of Experiment and Novel Multidimensional Robustness Diagrams Fulltext Access 10 Pages 2018
Albendazole nanocrystals: Optimization, spectroscopic, thermal and anthelmintic studies Fulltext Access 10 Pages 2018
Nanoparticles of Combretum quadrangulare leaf extract induce cytotoxicity, apoptosis, cell cycle arrest and anti-migration in lung cancer cells Fulltext Access 10 Pages 2018
Cosmetic and pharmaceutical qualifications of Egyptian bentonite and its suitability as drug carrier for Praziquantel drug Fulltext Access 10 Pages 2018
Inkjet printing of paracetamol and indomethacin using electromagnetic technology: Rheological compatibility and polymorphic selectivity Fulltext Access 10 Pages 2018
Selection of a round convex tablet shape that mitigates the risk of chipping and capping based on systematic evaluation by utilizing multivariate analysis Fulltext Access 10 Pages 2018
Delivery of adapalene using a novel topical gel based on tea tree oil nano-emulsion: Permeation, antibacterial and safety assessments Fulltext Access 10 Pages 2018
Dissolving polymeric microneedle arrays for enhanced site-specific acyclovir delivery Fulltext Access 10 Pages 2018
Synthesis and biological evaluation of novel tricyclic matrinic derivatives as potential anti-filovirus agents Fulltext Access 10 Pages 2018
Applications of stimuli-responsive nanoscale drug delivery systems in translational research Fulltext Access 10 Pages 2018
Circulatory-cell-mediated nanotherapeutic approaches in disease targeting Fulltext Access 10 Pages 2018
Novel nanotherapeutic strategies: fabrication approaches, application and clinical challenges Fulltext Access 10 Pages 2018
Upgrading and expanding the scope of homogeneous transfer hydrogenation Fulltext Access 10 Pages 2018
Developing precision medicine using scarless genome editing of human pluripotent stem cells Fulltext Access 10 Pages 2018
Analysis of the powder behavior and the residence time distribution within a production scale rotary tablet press Fulltext Access 10 Pages 2018
The effect of amorphous and crystal sodium warfarin and its content uniformity on bioequivalence of tablets Fulltext Access 10 Pages 2018
Inverse relationship between human erythrocyte fructose-6-phosphate and short-chain fatty acid levels Fulltext Access 10 Pages 2018
Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1 Fulltext Access 10 Pages 2018
Enhanced neural stem cell functions in conductive annealed carbon nanofibrous scaffolds with electrical stimulation Fulltext Access 10 Pages 2018
Theoretical study on crystal morphologies of 1,1-diamino-2,2-dinitroethene in solvents: Modified attachment energy model and occupancy model Fulltext Access 10 Pages 2018
A Tutorial for Developing a Topical Cream Formulation Based on the Quality by Design Approach Fulltext Access 10 Pages 2018
Tunable Surface Plasmon Resonance-Based Remote Actuation of Bimetallic Core-Shell Nanoparticle-Coated Stimuli Responsive Polymer for Switchable Chemo-Photothermal Synergistic Cancer Therapy Fulltext Access 10 Pages 2018
Mechanistic studies of hydrogen-peroxide-mediated anthocyanin oxidation Fulltext Access 10 Pages 2018
Mucoadhesive nanostructured polyelectrolytes complexes modulate the intestinal permeability of methotrexate Fulltext Access 10 Pages 2018
Effective cancer therapy based on selective drug delivery into cells across their membrane using receptor-mediated endocytosis Fulltext Access 10 Pages 2018
Optimization of diarylpentadienones as chemotherapeutics for prostate cancer Fulltext Access 10 Pages 2018
Post-reexposure administration of riluzole attenuates the reconsolidation of conditioned fear memory in rats Fulltext Access 10 Pages 2018
Inhibition of the hypercapnic ventilatory response by adenosine in the retrotrapezoid nucleus in awake rats Fulltext Access 10 Pages 2018
Postulating the major environmental condition resulting in the expression of essential hypertension and its associated cardiovascular diseases: Dietary imprudence in daily selection of foods in respect of their potassium and sodium content resulting in ox Fulltext Access 10 Pages 2018
Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems Fulltext Access 10 Pages 2018
Pyridazinone hybrids: Design, synthesis and evaluation as potential anticonvulsant agents Fulltext Access 10 Pages 2018
Seek & Destroy, use of targeting peptides for cancer detection and drug delivery Fulltext Access 10 Pages 2018
Practical application of ligand efficiency metrics in lead optimisation Fulltext Access 10 Pages 2018
Design, synthesis and pharmacological evaluation of some novel indanone derivatives as acetylcholinesterase inhibitors for the management of cognitive dysfunction Fulltext Access 10 Pages 2018
Characterizing hydration sites in protein-ligand complexes towards the design of novel ligands Fulltext Access 10 Pages 2018
Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1 Fulltext Access 10 Pages 2018
Design, synthesis, and biological evaluation of novel substituted benzamide derivatives bearing a 1,2,3-triazole moiety as potent human dihydroorotate dehydrogenase inhibitors Fulltext Access 10 Pages 2018
Novel pyrimidine-pyridine hybrids: Synthesis, cyclooxygenase inhibition, anti-inflammatory activity and ulcerogenic liability Fulltext Access 10 Pages 2018
Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2 Fulltext Access 10 Pages 2018
Picolyl amides of betulinic acid as antitumor agents causing tumor cell apoptosis Fulltext Access 10 Pages 2018
Novel carbamate derivatives as selective butyrylcholinesterase inhibitors Fulltext Access 10 Pages 2018
Evaluating oral flavorant effects on nicotine self-administration behavior and phasic dopamine signaling Fulltext Access 10 Pages 2018
An evaluation of neonicotinoids' potential to inhibit human cholinesterases: Protein-ligand docking and interaction profiling studies Fulltext Access 10 Pages 2018
Does high pressure have any effect on the structure of alpha amylase and its ability to binding to the oligosaccharides having 3-7 residues? Molecular dynamics study Fulltext Access 10 Pages 2018
Transition-metal-catalyzed cyclization reactions using vinyl and ethynyl benzoxazinones as dipole precursors Fulltext Access 10 Pages 2018
Synthesis of an electronically-tuned minimally interfering alkynyl photo-affinity label to measure small molecule-protein interactions Fulltext Access 10 Pages 2018
Uptake and bioreactivity of charged chitosan-coated superparamagnetic nanoparticles as promising contrast agents for magnetic resonance imaging Fulltext Access 10 Pages 2018
Synthesis of a novel fused pyrrolodiazepine-based library with anti-cancer activity Fulltext Access 11 Pages 2018
Hot Melt Extrudates Formulated Using Design Space: One Simple Process for Both Palatability and Dissolution Rate Improvement Fulltext Access 11 Pages 2018
Aging is an adaptation that selects in animals against disruption of homeostasis Fulltext Access 11 Pages 2018
Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia Fulltext Access 11 Pages 2018
Linked help from bacterial proteins drives autoantibody production in small vessel vasculitis Fulltext Access 11 Pages 2018
Silibinin phosphodiester glyco-conjugates: Synthesis, redox behaviour and biological investigations Fulltext Access 11 Pages 2018
Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates Fulltext Access 11 Pages 2018
Syntheses, antiviral activities and induced resistance mechanisms of novel quinazoline derivatives containing a dithioacetal moiety Fulltext Access 11 Pages 2018
Design, synthesis, monoamine oxidase inhibition and docking studies of new dithiocarbamate derivatives bearing benzylamine moiety Fulltext Access 11 Pages 2018
Palladium catalyzed Mizoroki-Heck reaction of pyrimidin-2-yl tosylates with aromatic and aliphatic olefins Fulltext Access 11 Pages 2018
Evaluation of a lifestyle intervention program in primary care on physical and mental health and quality of life of cancer survivors: A pilot study Fulltext Access 11 Pages 2018
Synthesis and biological evaluation of pyrimidine bridged combretastatin derivatives as potential anticancer agents and mechanistic studies Fulltext Access 11 Pages 2018
Synthesis of steroidal imidazolidinthiones as potential apoptotic agents: Investigation by theoretical and experimental studies Fulltext Access 11 Pages 2018
The importance of differentiating the three modalities of Tai Chi Chuan practice in clinical trials - A critical review Fulltext Access 11 Pages 2018
Using sulfinamides as high oxidation state sulfur reagent for preparation of sulfenamides Fulltext Access 11 Pages 2018
Advances in chemoselective and/or stereoselective semihydrogenation of alkynes Fulltext Access 11 Pages 2018
Ferritin and neuromelanin “quantum dot” array structures in dopamine neurons of the substantia nigra pars compacta and norepinephrine neurons of the locus coeruleus Fulltext Access 11 Pages 2018
Dynamic analysis on the calcium oscillation model considering the influences of mitochondria Fulltext Access 11 Pages 2018
Photochemical activity of membrane-localised polyketide derived marine natural products Fulltext Access 11 Pages 2018
Market entry, power, pharmacokinetics: what makes a successful drug innovation? Fulltext Access 11 Pages 2018
Demonstrating significant benefit of orphan medicines: analysis of 15 years of experience in Europe Fulltext Access 11 Pages 2018
Cyclic peptide inhibitors of lysine-specific demethylase 1 with improved potency identified by alanine scanning mutagenesis Fulltext Access 11 Pages 2018
A laboratory investigation of the antimicrobial activity of a selection of western phytomedicinal tinctures Fulltext Access 11 Pages 2018
Relating Observed Psychoactive Effects to the Plasma Concentrations of Delta-9-Tetrahydrocannabinol and Its Active Metabolite: An Effect-Compartment Modeling Approach Fulltext Access 11 Pages 2018
Preparation and evaluation of clindamycin phosphate loaded chitosan/alginate polyelectrolyte complex film as mucoadhesive drug delivery system for periodontal therapy Fulltext Access 11 Pages 2018
Understanding effects of process parameters and forced feeding on die filling Fulltext Access 11 Pages 2018
Anti-inflammatory hybrids of secondary amines and amide-sulfamide derivatives Fulltext Access 11 Pages 2018
Free radical rearrangement synthesis and microbiological evaluation of novel 2-sulfoether-4-quinolone scaffolds as potential antibacterial agents Fulltext Access 11 Pages 2018
Improving sustained drug delivery from ophthalmic lens materials through the control of temperature and time of loading Fulltext Access 11 Pages 2018
Modulating the degree of fucosylation of fucosylated chondroitin sulfate enhances heparin cofactor II-dependent thrombin inhibition Fulltext Access 11 Pages 2018
Drug transport mechanisms and in vitro release kinetics of vancomycin encapsulated chitosan-alginate polyelectrolyte microparticles as a controlled drug delivery system Fulltext Access 11 Pages 2018
Poly(2-Ethyl-2-Oxazoline) as an Alternative to Poly(Vinylpyrrolidone) in Solid Dispersions for Solubility and Dissolution Rate Enhancement of Drugs Fulltext Access 11 Pages 2018
Synthesis and anti-influenza virus evaluation of triterpene-sialic acid conjugates Fulltext Access 11 Pages 2018