Model development and prediction of particle size distribution, density and friability of a comilling operation in a continuous pharmaceutical manufacturing process Fulltext Access 12 Pages 2018
Mechanisms by which crystalline mannitol improves the reconstitution time of high concentration lyophilized protein formulations Fulltext Access 12 Pages 2018
The application of dual-electrode through vial impedance spectroscopy for the determination of ice interface temperatures, primary drying rate and vial heat transfer coefficient in lyophilization process development Fulltext Access 12 Pages 2018
Downstream processing from melt granulation towards tablets: In-depth analysis of a continuous twin-screw melt granulation process using polymeric binders Fulltext Access 12 Pages 2018
Novel therapeutic drug identification and gene correlation for fatty liver disease using high-content screening: Proof of concept Fulltext Access 12 Pages 2018
Improvement of Tenofovir vaginal release from hydrophilic matrices through drug granulation with hydrophobic polymers Fulltext Access 12 Pages 2018
Electrohydrodynamic methods for the development of pulmonary drug delivery systems Fulltext Access 12 Pages 2018
Intradermal Delivery of a Near-Infrared Photosensitizer Using Dissolving Microneedle Arrays Fulltext Access 12 Pages 2018
Impact of Superdisintegrants and Film Thickness on Disintegration Time of Strip Films Loaded With Poorly Water-Soluble Drug Microparticles Fulltext Access 12 Pages 2018
Comparative Assessment of Miniaturized Screening Approaches for Selection of Polymers for Amorphous Drug Stabilization Fulltext Access 12 Pages 2018
Injectable Hydrogels for Localized Chemotherapy and Radiotherapy in Brain Tumors Fulltext Access 12 Pages 2018
Bioactive flavonoids in medicinal plants: Structure, activity and biological fate Fulltext Access 12 Pages 2018
Investigating the impact of design characteristics on statistical efficiency within discrete choice experiments: A systematic survey Fulltext Access 12 Pages 2018
Evaluation of critical parameters for in vitro skin permeation and penetration studies using animal skin models Fulltext Access 12 Pages 2018
In situ fabrication of mesoporous silica-coated silver-gold hollow nanoshell for remotely controllable chemo-photothermal therapy via phase-change molecule as gatekeepers Fulltext Access 12 Pages 2018
The effect of the composition of a fixed dose combination on bioequivalence results Fulltext Access 12 Pages 2018
Multi-drug delivery system based on lipid membrane mimetic coated nano-hydroxyapatite formulations Fulltext Access 12 Pages 2018
Downstream processing of a ternary amorphous solid dispersion: The impacts of spray drying and hot melt extrusion on powder flow, compression and dissolution Fulltext Access 12 Pages 2018
Process analytical technology in continuous manufacturing of a commercial pharmaceutical product Fulltext Access 12 Pages 2018
A comparative analysis for the volatile compounds of various Chinese dark teas using combinatory metabolomics and fungal solid-state fermentation Fulltext Access 12 Pages 2018
Practice makes perfect: A systematic review of the expertise development of pharmacist and nurse independent prescribers in the United Kingdom Fulltext Access 12 Pages 2018
Effect of combined gliclazide/metformin treatment on oxidative stress, lipid profile, and hepatorenal functions in type 2 diabetic patients Fulltext Access 12 Pages 2018
Synthesis and biological evaluation of novel benzofuroxan-based pyrrolidine hydroxamates as matrix metalloproteinase inhibitors with nitric oxide releasing activity Fulltext Access 12 Pages 2018
Material tracking in a continuous direct capsule-filling process via residence time distribution measurements Fulltext Access 12 Pages 2018
Past, Present, and Future of Bioequivalence: Improving Assessment and Extrapolation of Therapeutic Equivalence for Oral Drug Products Fulltext Access 12 Pages 2018
Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents Fulltext Access 12 Pages 2018
Solid lipid nanoparticles modified with amphipathic chitosan derivatives for improved stability in the gastrointestinal tract Fulltext Access 12 Pages 2018
Profiling of dalcetrapib metabolites in human plasma by accelerator mass spectrometry and investigation of the free phenothiol by derivatisation with methylacrylate Fulltext Access 12 Pages 2018
Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease Fulltext Access 12 Pages 2018
Quantitative assessment of betamethasone dual-acting formulation in urine of patients with rheumatoid arthritis and ankylosing spondylitis after single-dose intramuscular administration and its application to long-term pharmacokinetic study Fulltext Access 12 Pages 2018
Development of benzoxazole deoxybenzoin oxime and acyloxylamine derivatives targeting innate immune sensors and xanthine oxidase for treatment of gout Fulltext Access 12 Pages 2018
Identification of degradation products of praziquantel during the mechanochemical activation Fulltext Access 12 Pages 2018
Nanomaterial-based biosensors and immunosensors for quantitative determination of cardiac troponins Fulltext Access 12 Pages 2018
Stability behaviour of antiretroviral drugs and their combinations. 8: Characterization and in-silico toxicity prediction of degradation products of efavirenz Fulltext Access 12 Pages 2018
The potential for clinical translation of antibody-targeted nanoparticles in the treatment of acute myeloid leukaemia Fulltext Access 13 Pages 2018
Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates Fulltext Access 13 Pages 2018
A novel series of 4-methyl substituted pyrazole derivatives as potent glucagon receptor antagonists: Design, synthesis and evaluation of biological activities Fulltext Access 13 Pages 2018
Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids Fulltext Access 13 Pages 2018
Alternative Manufacturing Concepts for Solid Oral Dosage Forms From Drug Nanosuspensions Using Fluid Dispensing and Forced Drying Technology Fulltext Access 13 Pages 2018
Syntheses and structure-activity relationships on antibacterial and anti-ulcerative colitis properties of quaternary 13-substituted palmatines and 8-oxo-13-substituted dihydropalmatines Fulltext Access 13 Pages 2018
Enhanced brain delivery with lower hepatic exposure of lazaroid loaded nanostructured lipid carriers developed using a design of experiment approach Fulltext Access 13 Pages 2018
Synthesis and evaluation of novel dimethylpyridazine derivatives as hedgehog signaling pathway inhibitors Fulltext Access 13 Pages 2018
Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy Fulltext Access 13 Pages 2018
Transporter-mediated natural product-drug interactions for the treatment of cardiovascular diseases Fulltext Access 13 Pages 2018
The degree of integration of non-dispensing pharmacists in primary care practice and the impact on health outcomes: A systematic review Fulltext Access 13 Pages 2018
Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles Fulltext Access 13 Pages 2018
Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation Fulltext Access 13 Pages 2018
Incorporation of histone deacetylase inhibitory activity into the core of tamoxifen - A new hybrid design paradigm Fulltext Access 13 Pages 2018
Metabolomics in chronic kidney disease: Strategies for extended metabolome coverage Fulltext Access 13 Pages 2018
Vesicular carriers containing phenylethyl resorcinol for topical delivery system; liposomes, transfersomes and invasomes Fulltext Access 13 Pages 2018
Development of a new doubly-labeled fluorescent ceramide probe for monitoring the metabolism of sphingolipids in living cells Fulltext Access 13 Pages 2018
Detailed modeling and process design of an advanced continuous powder mixer Fulltext Access 13 Pages 2018
Using elongated microparticles to enhance tailorable nanoemulsion delivery in excised human skin and volunteers Fulltext Access 13 Pages 2018
Primary deuterium kinetic isotope effects prolong drug release and polymer biodegradation in a drug delivery system Fulltext Access 13 Pages 2018
Effect of temperature ramp rate during the primary drying process on the properties of amorphous-based lyophilized cake, Part 2: Successful lyophilization by adopting a fast ramp rate during primary drying in protein formulations Fulltext Access 13 Pages 2018
Preclinical models for colonic absorption, application to controlled release formulation development Fulltext Access 13 Pages 2018
Implantable chemothermal brachytherapy seeds: A synergistic approach to brachytherapy using polymeric dual drug delivery and hyperthermia for malignant solid tumor ablation Fulltext Access 13 Pages 2018
Screening therapeutics according to their uptake across the blood-brain barrier: A high throughput method based on immobilized artificial membrane liquid chromatography-diode-array-detection coupled to electrospray-time-of-flight mass spectrometry Fulltext Access 13 Pages 2018
Natural compounds and combination therapy in colorectal cancer treatment Fulltext Access 13 Pages 2018
Synthesis and biological evaluation of novel bavachinin analogs as anticancer agents Fulltext Access 13 Pages 2018
Development and Characterization of Chitosan Cross-Linked With Tripolyphosphate as a Sustained Release Agent in Tablets, Part I: Design of Experiments and Optimization Fulltext Access 13 Pages 2018
Impact of fast and conservative freeze-drying on product quality of protein-mannitol-sucrose-glycerol lyophilizates Fulltext Access 13 Pages 2018
Synthesis and leishmanicidal activity of eugenol derivatives bearing 1,2,3-triazole functionalities Fulltext Access 13 Pages 2018
Urokinase receptor derived peptides as potent inhibitors of the formyl peptide receptor type 1-triggered cell migration Fulltext Access 13 Pages 2018
Development of polyvinylpyrrolidone/paclitaxel self-assemblies for breast cancer Fulltext Access 13 Pages 2018
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review Fulltext Access 13 Pages 2018
Curcumin drug delivery by vanillin-chitosan coated with calcium ferrite hybrid nanoparticles as carrier Fulltext Access 13 Pages 2018
Activation of phosphoinositide 3-kinase delta by antipsychotic drugs: Preliminary results Fulltext Access 13 Pages 2018
A novel approach for skin infections: Controlled release topical mats of poly(lactic acid)/poly(ethylene succinate) blends containing Voriconazole Fulltext Access 13 Pages 2018
Discovery of phenylsulfonylfuroxan derivatives as gamma globin inducers by histone acetylation Fulltext Access 13 Pages 2018
Tunable degradation of acetalated dextran microparticles enables controlled vaccine adjuvant and antigen delivery to modulate adaptive immune responses Fulltext Access 13 Pages 2018
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression Fulltext Access 13 Pages 2018
Merits and Limitations of Dynamic Vapor Sorption Studies on the Morphology and Physicochemical State of Freeze-Dried Products Fulltext Access 13 Pages 2018
Prospects of using nanotechnology for food preservation, safety, and security Fulltext Access 14 Pages 2018
Burn injury: Challenges and advances in burn wound healing, infection, pain and scarring Fulltext Access 14 Pages 2018
Chemical characterization with in vitro biological activities of Gypsophila species Fulltext Access 14 Pages 2018
Discovery of potent and selective Spleen Tyrosine Kinase inhibitors for the topical treatment of inflammatory skin disease Fulltext Access 14 Pages 2018
The influence of caffeine on ethyl glucuronide levels in rat serum and in rat hair Fulltext Access 14 Pages 2018
Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents Fulltext Access 14 Pages 2018
Matrix metalloprotease triggered bioresponsive drug delivery systems - Design, synthesis and application Fulltext Access 14 Pages 2018
Effect of pharmacist care on medication adherence and cardiovascular outcomes among patients post-acute coronary syndrome: AÂ systematic review Fulltext Access 14 Pages 2018
Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity - Exploring the armoury of obscurity Fulltext Access 14 Pages 2018
Current advanced therapy cell-based medicinal products for type-1-diabetes treatment Fulltext Access 14 Pages 2018
Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs Fulltext Access 14 Pages 2018
Multivariate monitoring for the industrialisation of a continuous wet granulation tableting process Fulltext Access 14 Pages 2018
Design, synthesis and anthelmintic activity of 7-keto-sempervirol analogues Fulltext Access 14 Pages 2018
Novel excipients - Regulatory challenges and perspectives - The EU insight Fulltext Access 14 Pages 2018
Design, synthesis and biological evaluation of anti-pancreatic cancer activity of plinabulin derivatives based on the co-crystal structure Fulltext Access 14 Pages 2018
New phenylaniline derivatives as modulators of amyloid protein precursor metabolism Fulltext Access 14 Pages 2018
Curcumin Cocrystal Micelles-Multifunctional Nanocomposites for Management of Neurodegenerative Ailments Fulltext Access 14 Pages 2018