Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues Fulltext Access 14 Pages 2009
Transcriptional targeting to brain cells: Engineering cell type-specific promoter containing cassettes for enhanced transgene expression Fulltext Access 14 Pages 2009
Zinc-finger-based artificial transcription factors and their applications Fulltext Access 14 Pages 2009
Pharmacokinetics and pharmacogenomics in esophageal cancer chemoradiotherapy Fulltext Access 14 Pages 2009
Structure, stability, and antiplatelet activity of O-acyl derivatives of salicylic acid and lipophilic esters of acetylsalicylate Fulltext Access 14 Pages 2009
Age-dependent stimulatory effect of desipramine and fluoxetine pretreatment on metastasis formation by B16F10 melanoma in male C57BL/6 mice Fulltext Access 14 Pages 2009
Drug delivery systems in HIV pharmacotherapy: What has been done and the challenges standing ahead Fulltext Access 14 Pages 2009
Intra-articular drug delivery systems for the treatment of rheumatic diseases: A review of the factors influencing their performance Fulltext Access 14 Pages 2009
Synthesis and antimycobacterial activities of novel 6-nitroquinolone-3-carboxylic acids Fulltext Access 14 Pages 2009
Larvicidal activities of some organotin compounds on mosquito larvae: A QSAR study Fulltext Access 14 Pages 2009
Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamides Fulltext Access 14 Pages 2009
QSAR models for 2-amino-6-arylsulfonylbenzonitriles and congeners HIV-1 reverse transcriptase inhibitors based on linear and nonlinear regression methods Fulltext Access 14 Pages 2009
Novel modifications in the series of O-(2-phthalimidoethyl)-N-substituted thiocarbamates and their ring-opened congeners as non-nucleoside HIV-1 reverse transcriptase inhibitors Fulltext Access 14 Pages 2009
3D-QSAR studies of boron-containing dipeptides as proteasome inhibitors with CoMFA and CoMSIA methods Fulltext Access 14 Pages 2009
Homology modeling of MCH1 receptor and validation by docking/scoring and protein-aligned CoMFA Fulltext Access 14 Pages 2009
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity: Part 2 Fulltext Access 14 Pages 2009
Chemical profiling of Radix Paeoniae evaluated by ultra-performance liquid chromatography/photo-diode-array/quadrupole time-of-flight mass spectrometry Fulltext Access 14 Pages 2009
Effects of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on rat CYP1A2 expression and metabolism of model CYP1A2 probe substrates Fulltext Access 14 Pages 2009
The impact of nonreferral outpatient co-payment on medical care utilization and expenditures in Taiwan Fulltext Access 14 Pages 2009
A review of counseling practices on prescription medicines in community pharmacies Fulltext Access 14 Pages 2009
Continuing effects of Medicare Part D on rural independent pharmacies who are the sole retail provider in their community Fulltext Access 14 Pages 2009
The corporatization of community pharmacy: Implications for service provision, the public health function, and pharmacy's claims to professional status in the United Kingdom Fulltext Access 14 Pages 2009
Social reactions to Valium and Prozac: A cultural lag perspective of drug diffusion and adoption Fulltext Access 14 Pages 2009
Effect of homobifunctional crosslinkers on nucleic acids delivery ability of PEI nanoparticles Fulltext Access 14 Pages 2009
Quality by design approach to understand the process of nanosuspension preparation Fulltext Access 14 Pages 2009
Mapping of solution components, pH changes, protein stability and the elimination of protein precipitation during freeze–thawing of fibroblast growth factor 20 Fulltext Access 14 Pages 2009
Design, biometric simulation and optimization of a nano-enabled scaffold device for enhanced delivery of dopamine to the brain Fulltext Access 14 Pages 2009
Applications of nanoparticles in topical drug delivery and in cosmetics Fulltext Access 14 Pages 2009
Effects of ionizing radiation sterilization on microparticulate drug delivery systems based on poly-α-hydroxyacids: an overview Fulltext Access 14 Pages 2009
Recent advances on transdermal iontophoretic drug delivery and non-invasive sampling Fulltext Access 14 Pages 2009
Putting the pieces together in diabetes research: Towards a hierarchical model of whole-body glucose homeostasis Fulltext Access 14 Pages 2009
Mutational ‘hot-spots’ in mammalian, bacterial and protozoal dihydrofolate reductases associated with antifolate resistance: Sequence and structural comparison Fulltext Access 14 Pages 2009
QSAR models for predicting enzymatic hydrolysis of new chemical entities in ‘soft-drug’ design Fulltext Access 14 Pages 2009
RCAI-37, 56, 59, 60, 92, 101, and 102, cyclitol and carbasugar analogs of KRN7000: Their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines Fulltext Access 14 Pages 2009
Separation of α-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LXRα-selective antagonists Fulltext Access 14 Pages 2009
Molecular recognition in the P2Y14 receptor: Probing the structurally permissive terminal sugar moiety of uridine-5′-diphosphoglucose Fulltext Access 14 Pages 2009
Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET Fulltext Access 14 Pages 2009
Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration Fulltext Access 14 Pages 2009
Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas Fulltext Access 14 Pages 2009
Discovery and structure–activity relationships of 4-aminoquinazoline derivatives, a novel class of opioid receptor like-1 (ORL1) antagonists Fulltext Access 14 Pages 2009
Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and β-secretase Fulltext Access 14 Pages 2009
Synthesis and cytotoxic activity of 5,6-heteroaromatically annulated pyridine-2,4-diamines Fulltext Access 14 Pages 2009
Synthesis and structure–activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors Fulltext Access 14 Pages 2009
Synthesis and structure–activity relationships of radicicol derivatives and WNT-5A expression inhibitory activity Fulltext Access 14 Pages 2009
3D-QSAR studies of 2,2-diphenylpropionates to aid discovery of novel potent muscarinic antagonists Fulltext Access 14 Pages 2009
Studies on novel 2-imidazolidinones and tetrahydropyrimidin-2(1H)-ones as potential TACE inhibitors: Design, synthesis, molecular modeling, and preliminary biological evaluation Fulltext Access 14 Pages 2009
p-Guanidinoethyl calixarene and parent phenol derivatives exhibiting antibacterial activities. Synthesis and biological evaluation Fulltext Access 14 Pages 2009
Towards Gram-negative antivirulence drugs: New inhibitors of HldE kinase Fulltext Access 14 Pages 2009
3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3 Fulltext Access 14 Pages 2009
Insect neuropeptides: Structures, chemical modifications and potential for insect control Fulltext Access 14 Pages 2009
Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugs Fulltext Access 14 Pages 2009
Synthesis, biological evaluation, and metabolic stability of acrylamide derivatives as novel CCR3 antagonists Fulltext Access 14 Pages 2009
ADMET rules of thumb II: A comparison of the effects of common substituents on a range of ADMET parameters Fulltext Access 14 Pages 2009
Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2 Fulltext Access 14 Pages 2009
Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents Fulltext Access 14 Pages 2009
Dual acting norepinephrine reuptake inhibitors and 5-HT2A receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles Fulltext Access 14 Pages 2009
Systematic syntheses of influenza neuraminidase inhibitors: A series of carbosilane dendrimers uniformly functionalized with thioglycoside-type sialic acid moieties Fulltext Access 14 Pages 2009
Functionalized 3-benzylidene-indolin-2-ones: Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1) with antiproliferative activity Fulltext Access 14 Pages 2009
Synthesis, biological assays and QSAR studies of N-(9-benzyl-2-phenyl-8-azapurin-6-yl)-amides as ligands for A1 adenosine receptors Fulltext Access 14 Pages 2009
Synthesis and biological evaluation of extraordinarily potent C-10 carba artemisinin dimers against P. falciparum malaria parasites and HL-60 cancer cells Fulltext Access 14 Pages 2009
Discovery of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride: A novel, potent and orally active direct inhibitor of factor Xa Fulltext Access 14 Pages 2009
Transdermal drug pharmacokinetics in man: Interindividual variability and partial prediction Fulltext Access 15 Pages 2009
Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products Fulltext Access 15 Pages 2009
Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: Exploration of 5–6 fused rings as alternative S1 moieties Fulltext Access 15 Pages 2009
Retinoid receptor subtype-selective modulators through synthetic modifications of RARγ agonists Fulltext Access 15 Pages 2009
Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum hypoxanthine–guanine–xanthine phosphoribosyltransferase Fulltext Access 15 Pages 2009
Synergy research: Vitamins and secondary plant components in the maintenance of the redox-homeostasis and in cell signaling Fulltext Access 15 Pages 2009
Identification, structure–activity relationships and molecular modeling of potent triamine and piperazine opioid ligands Fulltext Access 15 Pages 2009
Monitoring intracellular labile iron pools: A novel fluorescent iron(iii) sensor as a potential non-invasive diagnosis tool Fulltext Access 15 Pages 2009
Side chain azasteroids and thiasteroids as sterol methyltransferase inhibitors in ergosterol biosynthesis Fulltext Access 15 Pages 2009
Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors Fulltext Access 15 Pages 2009
Anthranilic acid based CCK1 receptor antagonists: Blocking the receptor with the same ‘words’ of the endogenous ligand Fulltext Access 15 Pages 2009
Synthesis and evaluation of imidazole–dioxolane compounds as selective heme oxygenase inhibitors: Effect of substituents at the 4-position of the dioxolane ring Fulltext Access 15 Pages 2009
Antimycobacterial activity of new 3,5-disubstituted 1,3,4-oxadiazol-2(3H)-one derivatives. Molecular modeling investigations Fulltext Access 15 Pages 2009
2-(Substituted phenyl)amino analogs of 1-methoxyspirobrassinol methyl ether: Synthesis and anticancer activity Fulltext Access 15 Pages 2009
New pyrazoline bearing 4(3H)-quinazolinone inhibitors of monoamine oxidase: Synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity Fulltext Access 15 Pages 2009