Chiral gossypol derivatives: Evaluation of their anticancer activity and molecular modeling Fulltext Access 12 Pages 2009
PEGylated PPI dendritic architectures for sustained delivery of H2 receptor antagonist Fulltext Access 12 Pages 2009
Design and development of dendrimer photosensitizer-incorporated polymeric micelles for enhanced photodynamic therapy Fulltext Access 12 Pages 2009
Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors Fulltext Access 12 Pages 2009
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: Docking-based CoMFA and CoMSIA analyses Fulltext Access 12 Pages 2009
11C-labelled PIB analogues as potential tracer agents for in vivo imaging of amyloid β in Alzheimer's disease Fulltext Access 12 Pages 2009
Identification of hydrolytically stable and selective P2Y1 receptor agonists Fulltext Access 12 Pages 2009
Recent advances in the use of cell-penetrating peptides for medical and biological applications Fulltext Access 12 Pages 2009
Effects of nitrite on modulating ROS generation following ischemia and reperfusion Fulltext Access 12 Pages 2009
Electrohydrodynamics: A facile technique to fabricate drug delivery systems Fulltext Access 12 Pages 2009
Novel 3,3′-diindolylmethane derivatives: Synthesis and cytotoxicity, structural characterization in solid state Fulltext Access 12 Pages 2009
Polymeric carriers: Preclinical safety and the regulatory implications for design and development of polymer therapeutics Fulltext Access 12 Pages 2009
Synthesis, spectral and biological evaluation of some new thiazolidinones and thiazoles based on t-3-alkyl-r-2,c-6-diarylpiperidin-4-ones Fulltext Access 12 Pages 2009
PEG conjugates in clinical development or use as anticancer agents: An overview Fulltext Access 12 Pages 2009
Novel ureas and thioureas of 15-membered azalides with antibacterial activity against key respiratory pathogens Fulltext Access 12 Pages 2009
Biological activity studies on metal complexes of novel tridentate Schiff base ligand. Spectroscopic and thermal characterization Fulltext Access 12 Pages 2009
Polymersome carriers: From self-assembly to siRNA and protein therapeutics Fulltext Access 12 Pages 2009
2-[2-Substituted-3-(3,4-dichlorobenzylamino)propylamino]-1H-quinolin-4-ones as Staphylococcus aureus methionyl-tRNA synthetase inhibitors Fulltext Access 12 Pages 2009
The influence of chitosan content in cationic chitosan/PLGA nanoparticles on the delivery efficiency of antisense 2′-O-methyl-RNA directed against telomerase in lung cancer cells Fulltext Access 12 Pages 2009
An ion pairing approach to increase the loading of hydrophilic and lipophilic drugs into PEGylated PLGA nanoparticles Fulltext Access 12 Pages 2009
Alginate–poloxamer microparticles for controlled drug delivery to mucosal tissue Fulltext Access 12 Pages 2009
The use of Eudragit® RS 100/cyclodextrin nanoparticles for the transmucosal administration of glutathione Fulltext Access 12 Pages 2009
Colon-specific mutual amide prodrugs of 4-aminosalicylic acid for their mitigating effect on experimental colitis in rats Fulltext Access 12 Pages 2009
Gene transfer to the lung: Lessons learned from more than 2 decades of CF gene therapy Fulltext Access 12 Pages 2009
‘Sum of activities’ as dependent parameter: A new CoMFA-based approach for the design of pan PPAR agonists Fulltext Access 12 Pages 2009
Physiological and pharmacological roles of ABCG2 (BCRP): Recent findings in Abcg2 knockout mice Fulltext Access 12 Pages 2009
Parallel synthesis, molecular modelling and further structure–activity relationship studies of new acylthiocarbamates as potent non-nucleoside HIV-1 reverse transcriptase inhibitors Fulltext Access 12 Pages 2009
Les cytokines du système immunitaire et leurs antagonistes en thérapeutique Fulltext Access 13 Pages 2009
Characterization of the naturally occurring Arg344His variant of the human 5-HT3A receptor Fulltext Access 13 Pages 2009
Novel nanomedicine-based MRI contrast agents for gynecological malignancies Fulltext Access 13 Pages 2009
Electrospinning of collagen/biopolymers for regenerative medicine and cardiovascular tissue engineering Fulltext Access 13 Pages 2009
Anti-diabetic effects of 1-methylnicotinamide (MNA) in streptozocin-induced diabetes in rats Fulltext Access 13 Pages 2009
Innovative strategies for co-delivering antigens and CpG oligonucleotides Fulltext Access 13 Pages 2009
Therapeutic strategies by modulating oxygen stress in cancer and inflammation Fulltext Access 13 Pages 2009
Oral osmotically driven systems: 30 years of development and clinical use Fulltext Access 13 Pages 2009
Starch-based coatings for colon-specific drug delivery. Part I: The influence of heat treatment on the physico-chemical properties of high amylose maize starches Fulltext Access 13 Pages 2009
Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib Fulltext Access 13 Pages 2009
An accurate, rapid and sensitive determination of tramadol and its active metabolite O-desmethyltramadol in human plasma by LC–MS/MS Fulltext Access 13 Pages 2009
Tetrahydroisoquinolines as dopaminergic ligands: 1-Butyl-7-chloro-6-hydroxy-tetrahydroisoquinoline, a new compound with antidepressant-like activity in mice Fulltext Access 13 Pages 2009
Synthesis, analgesic and anti-inflammatory activities evaluation of some bi-, tri- and tetracyclic condensed pyrimidines Fulltext Access 13 Pages 2009
Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors Fulltext Access 13 Pages 2009
Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists Fulltext Access 13 Pages 2009
Effect of potential amine prodrugs of selective neuronal nitric oxide synthase inhibitors on blood–brain barrier penetration Fulltext Access 13 Pages 2009
Synthesis and characterization of several carbamoyl- and methylcarbamoyl-substituted EMPO derivatives Fulltext Access 13 Pages 2009
Synthesis and structure–activity relationship of novel diarylpyrazole imide analogues as CB1 cannabinoid receptor ligands Fulltext Access 13 Pages 2009
Natural and synthetic 2′-hydroxy-chalcones and aurones: Synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity Fulltext Access 13 Pages 2009
Development and characterization of lysine based tripeptide analogues as inhibitors of Sir2 activity Fulltext Access 13 Pages 2009
N-Acylated and N,N′-diacylated imidazolidine-2-thione derivatives and N,N′-diacylated tetrahydropyrimidine-2(1H)-thione analogues: Synthesis and antiproliferative activity Fulltext Access 13 Pages 2009
Synthesis and structure–activity relationships of N-aryl(indol-3-yl)glyoxamides as antitumor agents Fulltext Access 13 Pages 2009
Toward establishing structure–activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells Fulltext Access 13 Pages 2009
Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: Exploration of 6–6 fused rings as alternative S1 moieties Fulltext Access 13 Pages 2009
Search for new pharmacophores for antimalarial activity. Part II: Synthesis and antimalarial activity of new 6-ureido-4-anilinoquinazolines Fulltext Access 13 Pages 2009
High transfection efficiency and low toxicity cationic lipids with aminoglycerol–diamine conjugate Fulltext Access 13 Pages 2009
Potent antitumor bifunctional DNA alkylating agents, synthesis and biological activities of 3a-aza-cyclopenta[a]indenes Fulltext Access 13 Pages 2009
Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: Synthesis and biological evaluation of antivascular activity Fulltext Access 13 Pages 2009
Simultaneous quantification of active components in the herbs and products of Si-Wu-Tang by high performance liquid chromatography–mass spectrometry Fulltext Access 13 Pages 2009
Simultaneous characterization of quaternary alkaloids, 8-oxoprotoberberine alkaloids, and a steroid compound in Coscinium fenestratum by liquid chromatography hybrid ion trap time-of-flight mass spectrometry Fulltext Access 13 Pages 2009
Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta Fulltext Access 13 Pages 2009
Effect of conjugates of all-trans-retinoic acid and shorter polyene chain analogues with amino acids on prostate cancer cell growth Fulltext Access 13 Pages 2009
Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis Fulltext Access 13 Pages 2009
Synthesis and serotonin receptor activity of the arylpiperazine alkyl/propoxy derivatives of new azatricycloundecanes Fulltext Access 13 Pages 2009
Possible anticancer agents: QSAR analogs of glutamamide: Synthesis and pharmacological activity of 1,5-N,Nâ²-disubstituted-2-(substituted benzenesulphonyl) glutamamides Fulltext Access 13 Pages 2009
Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivatives Fulltext Access 13 Pages 2009
Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors Fulltext Access 13 Pages 2009
Stereoselective synthesis and antimicrobial activity of benzofuran-based (1E)-1-(piperidin-1-yl)-N2-arylamidrazones Fulltext Access 13 Pages 2009
Discovery of potential new InhA direct inhibitors based on pharmacophoreand 3D-QSAR analysis followed by in silico screening Fulltext Access 13 Pages 2009
Chiral 3-(4,5-dihydrooxazol-2-yl)phenyl alkylcarbamates as novel FAAH inhibitors: Insight into FAAH enantioselectivity by molecular docking and interaction fields Fulltext Access 13 Pages 2009
3D-QSAR with the aid of pharmacophore search and docking-based alignments for farnesyltransferase inhibitors Fulltext Access 13 Pages 2009
Design, synthesis and evaluation of galanthamine derivatives as acetylcholinesterase inhibitors Fulltext Access 13 Pages 2009
Steroidal lactones as inhibitors of 17β-hydroxysteroid dehydrogenase type 5: Chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities Fulltext Access 13 Pages 2009
Synthesis, optimization and structure–activity relationships of 3,5-disubstituted isoxazolines as new anti-tuberculosis agents Fulltext Access 13 Pages 2009
Synthesis and in vitro antitumor activity of new quinoxaline derivatives Fulltext Access 13 Pages 2009
Highly twisted adamantyl arotinoids: Synthesis, antiproliferative effects and RXR transactivation profiles Fulltext Access 13 Pages 2009
Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4(3H)-quinazolinone analogs Fulltext Access 13 Pages 2009