General practitioners' and pharmacists' perceptions of the role of community pharmacists in delivering clinical services Fulltext Access 16 Pages 2009
Acyclic nucleoside bisphosphonates: Synthesis and properties of chiral 2-amino-4,6-bis[(phosphonomethoxy)alkoxy]pyrimidines Fulltext Access 17 Pages 2009
P-glycoprotein deficient mouse in situ blood–brain barrier permeability and its prediction using an in combo PAMPA model Fulltext Access 17 Pages 2009
Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system Fulltext Access 17 Pages 2009
Structure–activity relationship studies of a novel series of anthrax lethal factor inhibitors Fulltext Access 17 Pages 2009
Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers Fulltext Access 17 Pages 2009
In-line and real-time process monitoring of a freeze drying process using Raman and NIR spectroscopy as complementary process analytical technology (PAT) tools Fulltext Access 17 Pages 2009
Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor Fulltext Access 17 Pages 2009
Alantrypinone and its derivatives: Synthesis and antagonist activity toward insect GABA receptors Fulltext Access 17 Pages 2009
Mechanism-based inhibition of cytochrome P450 enzymes: An evaluation of early decision making in vitro approaches and drug-drug interaction prediction methods Fulltext Access 17 Pages 2009
Spiro(imidazo[1,2-a]pyrano[2,3-c]pyridine-9-indenes) as inhibitors of gastric acid secretion Fulltext Access 17 Pages 2009
Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications Fulltext Access 17 Pages 2009
13-Methyl-substituted des-C,D analogs of (20S)-1α,25-dihydroxy-2-methylene-19-norvitamin D3 (2MD): Synthesis and biological evaluation Fulltext Access 17 Pages 2009
α-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases Fulltext Access 17 Pages 2009
Transcriptionally regulated, prostate-targeted gene therapy for prostate cancer Fulltext Access 17 Pages 2009
Materials Science Tetrahedron-A Useful Tool for Pharmaceutical Research and Development Fulltext Access 17 Pages 2009
Relationships between the structure of 6-allyl-6,8-diazabicyclo[3.2.2]nonane derivatives and their σ receptor affinity and cytotoxic activity Fulltext Access 17 Pages 2009
Biochemical Mechanism of Acetaminophen (APAP) Induced Toxicity in Melanoma Cell Lines Fulltext Access 17 Pages 2009
Topical vehicles based on natural surfactant/fatty alcohols mixed emulsifier: The influence of two polyols on the colloidal structure and in vitro/in vivo skin performance Fulltext Access 18 Pages 2009
Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis Fulltext Access 18 Pages 2009
Methodology for development of a physiological model incorporating CYP3A and P-glycoprotein for the prediction of intestinal drug absorption Fulltext Access 18 Pages 2009
Detection of Protein Aggregates by Sedimentation Velocity Analytical Ultracentrifugation (SV-AUC): Sources of Variability and Their Relative Importance Fulltext Access 18 Pages 2009
Thermodynamic and structural aspects of sulfonamide crystals and solutions Fulltext Access 18 Pages 2009
Light-induced aggregation of type I soluble tumor necrosis factor receptor Fulltext Access 18 Pages 2009
Physical and biophysical effects of polysorbate 20 and 80 on darbepoetin alfa Fulltext Access 18 Pages 2009
Immunogenicity of aggregates of recombinant human growth hormone in mouse models Fulltext Access 18 Pages 2009
Structural stability of hepatitis C virus envelope glycoprotein E1: Effect of pH and dissociative detergents Fulltext Access 18 Pages 2009
Modeling microstructure development and release kinetics in controlled drug release coatings* Fulltext Access 18 Pages 2009
Dynamics and control of percutaneous drug absorption in the presence of epidermal turnover Fulltext Access 18 Pages 2009
Biodegradable poly(ɛ-caprolactone)–poly(ethylene glycol) copolymers as drug delivery system Fulltext Access 18 Pages 2009
Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays Fulltext Access 18 Pages 2009
Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-d-aspartate receptors Fulltext Access 18 Pages 2009
Synthesis and biological evaluation of flavan-3-ol derivatives as positive modulators of GABAA receptors Fulltext Access 18 Pages 2009
Solid-phase parallel synthesis and SAR of 4-amidofuran-3-one inhibitors of cathepsin S: Effect of sulfonamides P3 substituents on potency and selectivity Fulltext Access 18 Pages 2009
Substituted 1,2,3,4-tetrahydroquinolin-6-yloxypropanes as β3-adrenergic receptor agonists: Design, synthesis, biological evaluation and pharmacophore modeling Fulltext Access 18 Pages 2009
Photochemical electrocyclisation of 3-vinylindoles to pyrido[2,3-a]-, pyrido[4,3-a]- and thieno[2,3-a]-carbazoles: Design, synthesis, DNA binding and antitumor cell cytotoxicity Fulltext Access 18 Pages 2009
Development of HPMA copolymer–anticancer conjugates: Clinical experience and lessons learnt Fulltext Access 18 Pages 2009
Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron Fulltext Access 18 Pages 2009
Fighting Cancer: From the Bench to Bedside Using Second Generation Cationic Liposomal Therapeutics Fulltext Access 19 Pages 2009
Herbicidal 4-hydroxyphenylpyruvate dioxygenase inhibitors—A review of the triketone chemistry story from a Syngenta perspective Fulltext Access 19 Pages 2009
Evaluation of chemical degradation of a trivalent recombinant protein vaccine against botulinum neurotoxin by LysC peptide mapping and MALDI-TOF mass spectrometry Fulltext Access 19 Pages 2009
Local Mobility in Amorphous Pharmaceuticals—Characterization and Implications on Stability Fulltext Access 19 Pages 2009
Rapid Determination of Vial Heat Transfer Parameters Using Tunable Diode Laser Absorption Spectroscopy (TDLAS) in Response to Step-Changes in Pressure Set-Point During Freeze-Drying Fulltext Access 19 Pages 2009
Effects of Chemical Enhancers on Human Epidermal Membrane: Structure-Enhancement Relationship Based on Maximum Enhancement (Emax) Fulltext Access 19 Pages 2009
Electrospun materials as potential platforms for bone tissue engineering Fulltext Access 19 Pages 2009
Role of placental ATP-binding cassette (ABC) transporters in antiretroviral therapy during pregnancy Fulltext Access 19 Pages 2009
Solution studies on the complex of 4′-epiadriamycin-d-(CGATCG)2 followed by time-resolved fluorescence measurement, diffusion ordered spectroscopy and restrained molecular dynamics simulations Fulltext Access 19 Pages 2009
Novel amide derivatives as inhibitors of histone deacetylase: Design, synthesis and SAR Fulltext Access 19 Pages 2009
Search for new pharmacophores for antimalarial activity. Part I: Synthesis and antimalarial activity of new 2-methyl-6-ureido-4-quinolinamides Fulltext Access 19 Pages 2009
Identifying mechanisms of chronotolerance and chronoefficacy for the anticancer drugs 5-fluorouracil and oxaliplatin by computational modeling Fulltext Access 19 Pages 2009
Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity Fulltext Access 20 Pages 2009
Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase-4 for the treatment of type 2 diabetes Fulltext Access 20 Pages 2009
A Combined Pharmacokinetic-Pharmacodynamic (PK-PD) Model for Tumor Growth in the Rat with UFT Administration Fulltext Access 20 Pages 2009
A Novel Approach to Prepare Insulin-Loaded Poly (Lactic-Co-Glycolic Acid) Microcapsules and the Protein Stability Study Fulltext Access 20 Pages 2009
Characterization of High-Molecular-Weight Nonnative Aggregates and Aggregation Kinetics by Size Exclusion Chromatography With Inline Multi-Angle Laser Light Scattering Fulltext Access 20 Pages 2009
A comprehensive study of Sansalvamide A derivatives: The structure–activity relationships of 78 derivatives in two pancreatic cancer cell lines Fulltext Access 20 Pages 2009
QSPR modelling with the topological substructural molecular design approach: β-cyclodextrin complexation Fulltext Access 20 Pages 2009
Synthesis, characterization and derivatization of some novel types of mono- and bis-imidazolidineiminothiones and imidazolidineiminodithiones with antitumor, antiviral, antibacterial and antifungal activities – part I Fulltext Access 20 Pages 2009
Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions Fulltext Access 20 Pages 2009
Investigation of the micellar effect of pluronic P85 on P-glycoprotein inhibition: Cell accumulation and equilibrium dialysis studies Fulltext Access 21 Pages 2009
Hydrodynamic, mass transfer, and dissolution effects induced by tablet location during dissolution testing Fulltext Access 21 Pages 2009
Reprint of “Inspired by flowers: Synthetic routes to scalemic deltamethrinic acid” [Bioorg. Med. Chem. 17 (2009) 2555–2575] Fulltext Access 21 Pages 2009
Monoclonal antibody interactions with micro- and nanoparticles: Adsorption, aggregation, and accelerated stress studies Fulltext Access 21 Pages 2009
Lessons from nature: “Pathogen-Mimetic” systems for mucosal Nano-medicines Fulltext Access 21 Pages 2009
Development of a novel method for predicting human volume of distribution at steady-state of basic drugs and comparative assessment with existing methods Fulltext Access 21 Pages 2009
In-vitro tomography and non-destructive imaging at depth of pharmaceutical solid dosage forms Fulltext Access 21 Pages 2009
2,5-Disubstituted tetrahydrofurans as selective serotonin re-uptake inhibitors Fulltext Access 22 Pages 2009