Impact of sucrose level on storage stability of proteins in freeze-dried solids: II. Correlation of aggregation rate with protein structure and molecular mobility* Fulltext Access 22 Pages 2009
Role of Fixed Coefficients and Exponents in the Prediction of Human Drug Clearance: How Accurate are the Predictions from One or Two Species? Fulltext Access 22 Pages 2009
Benzhydrylquinazolinediones: Novel cytosolic phospholipase A2α inhibitors with improved physicochemical properties Fulltext Access 23 Pages 2009
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy Fulltext Access 23 Pages 2009
Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic Fulltext Access 23 Pages 2009
Recent developments in the design and synthesis of hybrid molecules basedon aminoquinoline ring and their antiplasmodial evaluation Fulltext Access 23 Pages 2009
Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability? Fulltext Access 24 Pages 2009
Stability of a Trivalent Recombinant Protein Vaccine Formulation Against Botulinum Neurotoxin During Storage in Aqueous Solution Fulltext Access 24 Pages 2009
Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores Fulltext Access 25 Pages 2009
Insecticidal heterolignans—Tubuline polymerization inhibitors with activity against chewing pests Fulltext Access 25 Pages 2009
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism Fulltext Access 26 Pages 2009
Synthesis and serotonin transporter activity of sulphur-substituted α-alkyl phenethylamines as a new class of anticancer agents Fulltext Access 27 Pages 2009
Fluidization technologies: Aerodynamic principles and process engineering Fulltext Access 28 Pages 2009
Physiology and pharmacology of melatonin in relation to biological rhythms Fulltext Access 28 Pages 2009
Process Modeling in the Pharmaceutical Industry using the Discrete Element Method Fulltext Access 29 Pages 2009
An insight into water of crystallization during processing using vibrational spectroscopy Fulltext Access 30 Pages 2009
Interleukin-2: Evaluation of Routes of Administration and Current Delivery Systems in Cancer Therapy Fulltext Access 31 Pages 2009
Pharmaceutical Aspects of Intranasal Delivery of Vaccines Using Particulate Systems Fulltext Access 32 Pages 2009
Principles, approaches, and challenges for predicting protein aggregation rates and shelf life Fulltext Access 32 Pages 2009
Calculation of Molecular Lipophilicity: State-of-the-Art and Comparison of Log P Methods on more than 96,000 Compounds Fulltext Access 33 Pages 2009
Multifunctional thioxanthone derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease Fulltext Access 39 Pages 2009
In vivo, in vitro and in silico methods for small molecule transfer across the BBB Fulltext Access 40 Pages 2009
Synthetic medicinal chemistry of selected antimalarial natural products Fulltext Access 40 Pages 2009
From natural bone grafts to tissue engineering therapeutics: Brainstorming on pharmaceutical formulative requirements and challenges Fulltext Access 59 Pages 2009
3rd BBBB-Bosphorus International Conference on Pharmaceutical Sciences Fulltext Access 220 Pages 2009
Effects of Cimicifuga racemosa extract on liver morphology and hepatic function indices Fulltext Access 4 Pages 2008
How do we compare dose to cells in vitro with dose to live animals and humans? Some experiences with inhaled substances Fulltext Access 4 Pages 2008
Antiprotozoal activity of (8-hydroxymethylen)-trieicosanyl acetate isolated from Senna villosa Fulltext Access 4 Pages 2008
Screening for cytotoxic activity of extracts and isolated alkaloids from bulbs of Hippeastrum vittatum Fulltext Access 4 Pages 2008
Effects of carvacrol upon the liver of rats undergoing partial hepatectomy Fulltext Access 4 Pages 2008
Inhibitory effect of compounds from Zingiberaceae species on human platelet aggregation Fulltext Access 4 Pages 2008
Aescin and troxerutin as a successful combination for the treatment of inner ear perfusion disturbances Fulltext Access 4 Pages 2008
The inhibition of Candida species by selected essential oils and their synergism with amphotericin B Fulltext Access 4 Pages 2008
Effect of total flavonoid fraction of Astragalus complanatus R.Brown on angiotensin II-induced portal-vein contraction in hypertensive rats Fulltext Access 4 Pages 2008
Nanocapsule@xerogel microparticles containing sodium diclofenac: A new strategy to control the release of drugs Fulltext Access 4 Pages 2008
Development of a CART Model to Predict the Synthesis of Cardiotoxic Daunorubicinol in Heart Tissue Samples From Donors With and Without Down Syndrome Fulltext Access 4 Pages 2008
Protein concentration and pH affect the apparent P-glycoprotein-ATPase activation kinetics Fulltext Access 4 Pages 2008
Maintaining a frozen shipping environment for Phase I clinical trial distribution Fulltext Access 4 Pages 2008
Effect of chitosan, benzalkonium chloride and ethylenediaminetetraacetic acid on permeation of acyclovir across isolated rabbit cornea Fulltext Access 4 Pages 2008
The spectrophotometric study of the binding of vitamin E to water + dimethyl sulfoxide and water + diethyl sulfoxide containing reversed micelles Fulltext Access 4 Pages 2008
Solid-state characterization of an NR2B selective N-methyl d-aspartate (NMDA) antagonist polymorphs Fulltext Access 4 Pages 2008
Tretinoin-loaded nanocapsules: Preparation, physicochemical characterization, and photostability study Fulltext Access 4 Pages 2008
Solubilisation of drugs in micellar solutions of diblock copolymers of ethylene oxide and styrene oxide Fulltext Access 4 Pages 2008
Lyotropic liquid crystal preconcentrates for the treatment of periodontal disease Fulltext Access 4 Pages 2008
Uniform-sized PLA nanoparticles: Preparation by premix membrane emulsification Fulltext Access 4 Pages 2008
The use of atomic force microscopy to study the conditioning of micronised budesonide Fulltext Access 4 Pages 2008
Particle size-dependent triggering of accelerated blood clearance phenomenon Fulltext Access 4 Pages 2008
Diblock copolymers of ethylene oxide and 1,2-butylene oxide in aqueous solution: Formation of unimolecular micelles Fulltext Access 4 Pages 2008
Cold field emission gun-scanning electron microscopy: A new tool for morphological and ultrastructural analysis of liposomes Fulltext Access 4 Pages 2008
Self-nanoemulsifying drug delivery system (SNEDDS) for oral delivery of protein drugs: III. In vivo oral absorption study Fulltext Access 4 Pages 2008
Effect of nicotine treatment and withdrawal on random-pattern skin flaps in rats Fulltext Access 4 Pages 2008
Development of Safe Protein Therapeutics: Preclinical, Clinical and Regulatory Issues Announcement Fulltext Access 4 Pages 2008
Triterpene based compounds with potent anti-maturation activity against HIV-1 Fulltext Access 4 Pages 2008
Novel oxime and oxime ether derivatives of 12,14-dichlorodehydroabietic acid: Design, synthesis, and BK channel-opening activity Fulltext Access 4 Pages 2008
N-confused porphyrin possessing glucamine-appendants: Aggregation and acid/base properties in aqueous media Fulltext Access 4 Pages 2008
Synthesis of a novel 6,14-epoxymorphinan derivative and its pharmacology Fulltext Access 4 Pages 2008
Orally bioavailable prodrugs of a BCS class 2 molecule, an inhibitor of HIV-1 reverse transcriptase Fulltext Access 4 Pages 2008
Structure–activity relationships of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the treatment of cough Fulltext Access 4 Pages 2008
Synthesis of BODIPY-labeled alkylphosphocholines with leishmanicidal activity, as fluorescent analogues of miltefosine Fulltext Access 4 Pages 2008
Development of Safe Protein Therapeutics: Preclinical, Clinical and Regulatory Issues Announcement Fulltext Access 4 Pages 2008
The EUFEPS workshop on institutional peer review “The ultimate tool to advance the pharmaceutical sciences?” Fulltext Access 4 Pages 2008
Eudragit S100 microparticles containing sodium pantoprazole: drug release, intestinal absorption and in vitro/ex vivo correlation Fulltext Access 4 Pages 2008
Drug-excipient interactions by Vitamin E-TPGS: in vitro studies on inhibition of P-glycoprotein and colonic drug absorption Fulltext Access 4 Pages 2008
Quantifying tight junction disruption caused by biomimetic pH-sensitive hydrogel drug carriers Fulltext Access 4 Pages 2008
Biphasic behavior of bupivacaine and cardiolipin-containing biomimetic membrane interaction Fulltext Access 4 Pages 2008
Carbonic anhydrase inhibitors: 2-Substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV Fulltext Access 4 Pages 2008
β-C-Glycosiduronic acids and β-C-glycosyl compounds: New PTP1B inhibitors Fulltext Access 4 Pages 2008
An endoplasmic reticulum (ER) stress-suppressive compound and its analogues from the mushroom Hericium erinaceum Fulltext Access 4 Pages 2008
N-Propylnoraporphin-11-O-yl carboxylic esters as potent dopamine D2 and serotonin 5-HT1A receptor dual ligands Fulltext Access 4 Pages 2008
Relative bioavailability of salicylic acid following dermal application of a 30% salicylic acid skin peel preparation Fulltext Access 4 Pages 2008