PTD-modified ATTEMPTS system for enhanced asparaginase therapy: A proof-of-concept investigation Fulltext Access 7 Pages 2008
Surface coating of PLGA microparticles with protamine enhances their immunological performance through facilitated phagocytosis Fulltext Access 7 Pages 2008
An in vivo comparison of intestinal pH and bacteria as physiological trigger mechanisms for colonic targeting in man Fulltext Access 7 Pages 2008
Gene delivery to dendritic cells mediated by complexes of lipoplexes and pH-sensitive fusogenic polymer-modified liposomes Fulltext Access 7 Pages 2008
Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo Fulltext Access 7 Pages 2008
Reactive oxygen species play a central role in the activity of cationic liposome based cancer vaccine Fulltext Access 7 Pages 2008
Non-invasive screening method for simultaneous evaluation of in vivo growth factor release profiles from multiple ectopic bone tissue engineering implants Fulltext Access 7 Pages 2008
Development of a vessel-simulating flow-through cell method for the in vitro evaluation of release and distribution from drug-eluting stents Fulltext Access 7 Pages 2008
Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice Fulltext Access 7 Pages 2008
Treatment of osteomyelitis in rats by injection of degradable polymer releasing gentamicin Fulltext Access 7 Pages 2008
Cellular accumulation and cytotoxicity of macromolecular platinum complexes in cisplatin-resistant tumor cells Fulltext Access 7 Pages 2008
Formulating erythropoietin-loaded sustained-release PLGA microspheres without protein aggregation Fulltext Access 7 Pages 2008
Cytokine adsorption/release on uniform magnetic nanoparticles for localized drug delivery Fulltext Access 7 Pages 2008
Poly(imidazole/DMAEA)phosphazene/DNA self-assembled nanoparticles for gene delivery: Synthesis and in vitro transfection Fulltext Access 7 Pages 2008
Non-toxic phototriggered gene transfection by PAMAM-porphyrin conjugates Fulltext Access 7 Pages 2008
Lipid cubic phases in topical drug delivery: Visualization of skin distribution using two-photon microscopy Fulltext Access 7 Pages 2008
Release of a model protein from biodegradable self assembled films for surface delivery applications Fulltext Access 7 Pages 2008
Dynamic microPET imaging of ultrasound contrast agents and lipid delivery Fulltext Access 7 Pages 2008
Controlled release carrier of BSA made by W/O/W emulsion method containing PLGA and hydroxyapatite Fulltext Access 7 Pages 2008
Increase of the pharmacological and pharmacokinetic efficacy of negatively charged polypeptide recombinant hirudin in rats via parenteral route by association with cationic liposomes Fulltext Access 7 Pages 2008
High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine Fulltext Access 7 Pages 2008
Modulation of microenvironmental pH and crystallinity of ionizable telmisartan using alkalizers in solid dispersions for controlled release Fulltext Access 7 Pages 2008
Development of time-, pH-, and enzyme-controlled colonic drug delivery using spray-dried chitosan acetate and hydroxypropyl methylcellulose Fulltext Access 7 Pages 2008
Is there a serious risk of resistance development to azoles among fungi due to the widespread use and long-term application of azole antifungals in medicine? Fulltext Access 7 Pages 2008
Preparation and pre-vivo evaluation of no-carrier-added, carrier-added and cross-complexed [68Ga]-EDTMP formulations Fulltext Access 7 Pages 2008
Sustained-release matrix tablets of metformin hydrochloride in combination with triacetyl-β-cyclodextrin Fulltext Access 7 Pages 2008
Novel preparation of enteric-coated chitosan-prednisolone conjugate microspheres and in vitro evaluation of their potential as a colonic delivery system Fulltext Access 7 Pages 2008
Oligomannose-coated liposomes as a therapeutic antigen-delivery and an adjuvant vehicle for induction of in vivo tumor immunity Fulltext Access 7 Pages 2008
Lipid nanoparticles for alkyl lysophospholipid edelfosine encapsulation: Development and in vitro characterization Fulltext Access 7 Pages 2008
A tumor targeted gene vector modified with G250 monoclonal antibody for gene therapy Fulltext Access 7 Pages 2008
Modular drug transporters with diphtheria toxin translocation domain form edged holes in lipid membranes Fulltext Access 7 Pages 2008
A new atherosclerotic lesion probe based on hydrophobically modified chitosan nanoparticles functionalized by the atherosclerotic plaque targeted peptides Fulltext Access 7 Pages 2008
Enhancement of skin permeation of docetaxel: A novel approach combining microneedle and elastic liposomes Fulltext Access 7 Pages 2008
Coating didodecyldimethylammonium bromide onto Au nanoparticles increases the stability of its complex with DNA Fulltext Access 7 Pages 2008
Evaluation of the effect of vector architecture on DNA condensation and gene transfer efficiency Fulltext Access 7 Pages 2008
Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis Fulltext Access 7 Pages 2008
Depot formulation of vasoactive intestinal peptide by protamine-based biodegradable nanoparticles Fulltext Access 7 Pages 2008
Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines Fulltext Access 7 Pages 2008
Synthesis of potential Rho-kinase inhibitors based on the chemistry of an original heterocycle: 4,4-Dimethyl-3,4-dihydro-1H-quinolin-2-one Fulltext Access 7 Pages 2008
Functionalized chalcones with basic functionalities have antibacterial activity against drug sensitive Staphylococcus aureus Fulltext Access 7 Pages 2008
Bioactivities of a series of phosphodiesterase type 5 (PDE-5) inhibitors as modelled by MIA-QSAR Fulltext Access 7 Pages 2008
Synthesis of 6-amino-1,4-dihydropyridines that prevent calcium overload and neuronal death Fulltext Access 7 Pages 2008
Synthesis and adenosine receptor binding studies of some novel triazolothienopyrimidines Fulltext Access 7 Pages 2008
Bioactivity of novel transition metal complexes of Nâ²-[(4-methoxy)thiobenzoyl]benzoic acid hydrazide Fulltext Access 7 Pages 2008
Evaluation of myorelaxant activity of 7-substituted hexahydroquinoline derivatives in isolated rabbit gastric fundus Fulltext Access 7 Pages 2008
Synthesis, characterization and in vitro release studies of a new acetazolamide–HP-β-CD–TEA inclusion complex Fulltext Access 7 Pages 2008
Synthesis of 2-aryl-4-(benzimidazol-2-yl)-1,2-dihydro[1,2,4]triazino-[4,5-a]benzimidazol-1-one derivatives with preferential cytotoxicity against carcinoma cell lines Fulltext Access 7 Pages 2008
Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi Fulltext Access 7 Pages 2008
Synthesis of biologically active N-methyl derivatives of amidines and cyclized five-membered products of amidines with oxalyl chloride Fulltext Access 7 Pages 2008
Design and synthesis of 2-(2,6-dibromophenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents Fulltext Access 7 Pages 2008
Synthesis of 2-sulfanyl-6-methyl-1,4-dihydropyrimidines as a new class of antifilarial agents Fulltext Access 7 Pages 2008
Synthesis and antiparasitic and antifungal evaluation of 2′-arylsubstituted-1H,1′H-[2,5′]bisbenzimidazolyl-5-carboxamidines Fulltext Access 7 Pages 2008
Synthesis and pharmacological screening of derivatives of isoxazolo[4,5-d]pyrimidine Fulltext Access 7 Pages 2008
Lanostane-type triterpenoids from the sclerotia of Inonotus obliquus possessing anti-tumor promoting activity Fulltext Access 7 Pages 2008
QSAR study about ATP-sensitive potassium channel activation of cromakalim analogues using CP-MLR approach Fulltext Access 7 Pages 2008
Synthesis and structure–activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives as potential agents against A549 lung cancer cells Fulltext Access 7 Pages 2008
Synthesis and pharmacological investigation of novel 4-(2-methylphenyl)-1-substituted-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-ones as new class of H1-antihistaminic agents Fulltext Access 7 Pages 2008
Synthesis and biological evaluation of diversely substituted indolin-2-ones Fulltext Access 7 Pages 2008
Synthesis and cytotoxicity studies of new dimethylamino-functionalised and aryl-substituted titanocene anti-cancer agents Fulltext Access 7 Pages 2008
Lipidization of human interferon-alpha: A new approach toward improving the delivery of protein drugs Fulltext Access 7 Pages 2008
Novel polymer carriers and gene constructs for treatment of myocardial ischemia and infarction Fulltext Access 7 Pages 2008
Tumor-targeted HPMA copolymer-(RGDfK)-(CHX-A″-DTPA) conjugates show increased kidney accumulation Fulltext Access 7 Pages 2008
Enhanced gene delivery using disulfide-crosslinked low molecular weight polyethylenimine with listeriolysin o-polyethylenimine disulfide conjugate Fulltext Access 7 Pages 2008
Mechanism of controlled drug release from a salting-out taste-masking system Fulltext Access 7 Pages 2008
The targeted behavior of thermally responsive nanohydrogel evaluated by NIR system in mouse model Fulltext Access 7 Pages 2008
Identification of a peptide ligand recognizing dysfunctional endothelial cells for targeting atherosclerosis Fulltext Access 7 Pages 2008
Controlled release evaluation of bacterial fertilizer using polymer composites as matrix Fulltext Access 7 Pages 2008
Controlled release of active as a consequence of the die diameter in solid lipid extrusion Fulltext Access 7 Pages 2008
Synthesis and CNS depressant activity of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones Fulltext Access 7 Pages 2008
The effect of dendrimers on the pharmacodynamic and pharmacokinetic behaviors of non-covalently or covalently attached drugs Fulltext Access 7 Pages 2008
Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens Fulltext Access 7 Pages 2008
Antimicrobial studies of 2,4-dichloro-5-fluorophenyl containing oxadiazoles Fulltext Access 7 Pages 2008
Cytotoxic 3,5-bis(benzylidene)piperidin-4-ones and N-acyl analogs displaying selective toxicity for malignant cells Fulltext Access 7 Pages 2008
Synthesis, cytotoxicity and DNA binding levels of tri-functional mononuclear platinum(II) complexes Fulltext Access 7 Pages 2008
Synthesis and characterization of novel azo-morphine derivatives for possible use in abused drugs analysis Fulltext Access 7 Pages 2008
GdCl3 catalysed Grieco condensation: A facile approach for the synthesis of novel pyrimidine and annulated pyrimidine fused indazole derivatives in single pot under mild conditions and their anti-microbial activity Fulltext Access 7 Pages 2008
Quantitative structure activity relationship studies on thiourea analogues as influenza virus neuraminidase inhibitors Fulltext Access 7 Pages 2008
Synthesis of some novel 2,4-disubstituted thiazoles as possible antimicrobial agents Fulltext Access 7 Pages 2008
Exploration of physicochemical properties and molecular modelling studies of 2-sulfonyl-phenyl-3-phenyl-indole analogs as cyclooxygenase-2 inhibitors Fulltext Access 7 Pages 2008
Non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 11: Structural modulations of diaryltriazines with potent anti-HIV activity Fulltext Access 7 Pages 2008
Novel N-(phosphonomethyl) glycine derivatives: Design, characterization and biological activity Fulltext Access 7 Pages 2008