The antioxidant activity of 2-(4(or 2)-hydroxyl-5-chloride-1,3-benzene-di-sulfanimide)-chitosan Fulltext Access 7 Pages 2008
Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anti-cancer activity (cytotoxic) against U937 leukemia cell lines Fulltext Access 7 Pages 2008
Design, synthesis and antiproliferative activity of some 3-benzylidene-2,3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells Fulltext Access 7 Pages 2008
Synthesis, physicochemical properties and antimicrobial evaluation of new (E)-chalcones Fulltext Access 7 Pages 2008
Peptidyl 3-substituted 1-hydroxyureas as isosteric analogues of succinylhydroxamate MMP inhibitors Fulltext Access 7 Pages 2008
Structure–activity relationships of Bak derived peptides: Affinity and specificity modulations by amino acid replacement Fulltext Access 7 Pages 2008
Novel bradykinin-1 antagonists containing a (1,2,3,4-tetrahydro-isoquinolin-1-yl)acetic acid scaffold Fulltext Access 7 Pages 2008
Synthesis, characterization, antifungal and anti-HIV activities of metal(II) complexes of 4,6-di-tert-butyl-3-[(2-hydroxyethyl)thio]benzene-1,2-diol Fulltext Access 7 Pages 2008
GRIND-based 3D-QSAR to predict inhibitory activity for similar enzymes, OSC and SHC Fulltext Access 7 Pages 2008
Synthesis and characterization of polyoxometalates loaded starch nanocomplex and its antitumoral activity Fulltext Access 7 Pages 2008
Synthesis and cytotoxicity evaluation of some benzimidazole-4,7-diones as bioreductive anticancer agents Fulltext Access 7 Pages 2008
A novel poloxamers/hyaluronic acid in situ forming hydrogel for drug delivery: Rheological, mucoadhesive and in vitro release properties Fulltext Access 8 Pages 2008
Studies on the reduction of tensile strength of tablets after roll compaction/dry granulation Fulltext Access 8 Pages 2008
A novel design of one-side coated biodegradable intrascleral implant for the sustained release of triamcinolone acetonide Fulltext Access 8 Pages 2008
Basic butylated methacrylate copolymer/kappa-carrageenan interpolyelectrolyte complex: Preparation, characterization and drug release behaviour Fulltext Access 8 Pages 2008
Preparation and characterisation of controlled release co-spray dried drug–polymer microparticles for inhalation 2: Evaluation of in vitro release profiling methodologies for controlled release respiratory aerosols Fulltext Access 8 Pages 2008
Water-free microencapsulation of proteins within PLGA microparticles by spray drying using PEG-assisted protein solubilization technique in organic solvent Fulltext Access 8 Pages 2008
Ex vivo evaluation of prolidase loaded chitosan nanoparticles for the enzyme replacement therapy Fulltext Access 8 Pages 2008
Sustained-release of buspirone HCl by co spray-drying with aqueous polymeric dispersions Fulltext Access 8 Pages 2008
Development of a novel osmotically driven drug delivery system for weakly basic drugs Fulltext Access 8 Pages 2008
Rationale for ibuprofen co-administration with antacids: Potential interaction mechanisms affecting drug absorption Fulltext Access 8 Pages 2008
Influence of hydroxypropyl-β-cyclodextrin on transdermal penetration and photostability of avobenzone Fulltext Access 8 Pages 2008
Transdermal and dermal delivery of adefovir: Effects of pH and permeation enhancers Fulltext Access 8 Pages 2008
γ-Irradiation effects on biopharmaceutical properties of PLGA microspheres loaded with SPf66 synthetic vaccine Fulltext Access 8 Pages 2008
Optimisation of an enteric coated, layered multi-particulate formulation for ileal delivery of viable recombinant Lactococcus lactis Fulltext Access 8 Pages 2008
Hydrophilic silica aerogels as dermal drug delivery systems – Dithranol as a model drug Fulltext Access 8 Pages 2008
Sustained release of bioactive glycosylated glial cell-line derived neurotrophic factor from biodegradable polymeric microspheres Fulltext Access 8 Pages 2008
In vitro/in vivo characterization of melt-molded gabapentin-loaded poly(epsilon-caprolactone) implants for sustained release in animal studies Fulltext Access 8 Pages 2008
Comparison of nanosuspensions and hydroxypropyl-β-cyclodextrin complex of melarsoprol: Pharmacokinetics and tissue distribution in mice Fulltext Access 8 Pages 2008
Bioavailability of amoxicillin and clavulanic acid from extended release tablets depends on intragastric tablet deposition and gastric emptying Fulltext Access 8 Pages 2008
Lipid nanoparticles as vehicles for topical psoralen delivery: Solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC) Fulltext Access 8 Pages 2008
Influence of compression forces on tablets disintegration by AC Biosusceptometry Fulltext Access 8 Pages 2008
Dissolution improvement of four poorly water soluble drugs by cogrinding with commonly used excipients Fulltext Access 8 Pages 2008
Cogrinding enhances the oral bioavailability of EMD 57033, a poorly water soluble drug, in dogs Fulltext Access 8 Pages 2008
In vivo evaluation of risperidone-SAIB in situ system as a sustained release delivery system in rats Fulltext Access 8 Pages 2008
Spray-dried microspheres based on methylpyrrolidinone chitosan as new carrier for nasal administration of metoclopramide Fulltext Access 8 Pages 2008
Stabilization of IgG by supercritical fluid drying: Optimization of formulation and process parameters Fulltext Access 8 Pages 2008
Folate-tethered emulsion for the target delivery of retinoids to cancer cells Fulltext Access 8 Pages 2008
Compound profiling for ABCC2 (MRP2) using a fluorescent microplate assay system Fulltext Access 8 Pages 2008
TRAIL receptor-targeted therapeutics: Resistance mechanisms and strategies to avoid them Fulltext Access 8 Pages 2008
Characterization of drug–chitosan interaction by 1H NMR, FTIR and isothermal titration calorimetry Fulltext Access 8 Pages 2008
In-line monitoring of granule moisture in fluidized-bed dryers using microwave resonance technology Fulltext Access 8 Pages 2008
Methylated N-(4-N,N-dimethylaminobenzyl) chitosan for novel effective gene carriers Fulltext Access 8 Pages 2008
An investigation into the effects of thermal history on the crystallisation behaviour of amorphous paracetamol Fulltext Access 8 Pages 2008
Influence of formulation and process parameters on the release characteristics of ethylcellulose sustained-release mini-matrices produced by hot-melt extrusion Fulltext Access 8 Pages 2008
In vitro and in vivo evaluation of tegaserod maleate pH-dependent tablets Fulltext Access 8 Pages 2008
Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica Fulltext Access 8 Pages 2008
Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety Fulltext Access 8 Pages 2008
Prise en charge des surdosages en antivitamine K, des situations à risques hémorragiques et des accidents hémorragiques chez les patients traités par antivitamine K en ville et en milieu hospitalier Fulltext Access 8 Pages 2008
Incorporation in polymeric nanocapsules improves the antioxidant effect of melatonin against lipid peroxidation in mice brain and liver Fulltext Access 8 Pages 2008
A novel gene delivery system for stable transfection of thiopurine-S-methyltransferase gene in versatile cell types Fulltext Access 8 Pages 2008
Specific interactions between diphenhydramine and α-helical poly(glutamic acid) – A new ion-pairing complex for taste masking and pH-controlled diphenhydramine release Fulltext Access 8 Pages 2008
Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities Fulltext Access 8 Pages 2008
Induction of immune tolerance to facilitate β cell regeneration in type 1 diabetes Fulltext Access 8 Pages 2008
Biopharmaceutical challenges associated with drugs with low aqueous solubility—The potential impact of lipid-based formulations Fulltext Access 8 Pages 2008
Synthesis and anticancer activity of new class of bisphosphonates/phosphanamidates Fulltext Access 8 Pages 2008
Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines bearing trichlorophenyl moiety Fulltext Access 8 Pages 2008
Epimers of bicyclo[2.2.2]octan-2-ol derivatives with antiprotozoal activity Fulltext Access 8 Pages 2008
New amido derivatives as potential BKCa potassium channel activators. XI Fulltext Access 8 Pages 2008
Synthesis and in vivo anti-mutagenic activity of novel melatonin derivatives Fulltext Access 8 Pages 2008
Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives Fulltext Access 8 Pages 2008
Preparation and characterization of technetium and rhenium tricarbonyl complexes bearing the 4-nitrobenzyl moiety as potential bioreductive diagnostic radiopharmaceuticals. In vitro and in vivo studies Fulltext Access 8 Pages 2008
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease Fulltext Access 8 Pages 2008
Oxoisoaporphine alkaloid derivatives: Synthesis, DNA binding affinity and cytotoxicity Fulltext Access 8 Pages 2008
Synthesis, characterization and biological activity of Pt(II) and Pt(IV) complexes with 5-methyl-5(4-pyridyl)-2,4-imidazolidenedione Fulltext Access 8 Pages 2008
Synthesis and antimicrobial activity of novel sulfone-linked bis heterocycles Fulltext Access 8 Pages 2008
Organotin(IV) complexes of 2-pyridineformamide-derived thiosemicarbazones: Antimicrobial and cytotoxic effects Fulltext Access 8 Pages 2008
NSAIDs revisited: Putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARγ) Fulltext Access 8 Pages 2008
Synthesis and structure–activity relationship of 3-phenylquinoxaline 1,4-di-N-oxide derivatives as antimalarial agents Fulltext Access 8 Pages 2008
Synthesis, characterization and antibacterial activity of cobalt(III) complexes with pyridine–amide ligands Fulltext Access 8 Pages 2008
Powder for reconstitution of the anti-HIV-1 drug TMC278 – Formulation development, stability and animal studies Fulltext Access 8 Pages 2008
Carboxymethyl high amylose starch: Chitosan self-stabilized matrix for probiotic colon delivery Fulltext Access 8 Pages 2008
Transport evaluation of salicylic acid and structurally related compounds across Caco-2 cell monolayers and artificial PAMPA membranes Fulltext Access 8 Pages 2008
Formulation development of freeze-dried oligonucleotide-loaded gelatin nanoparticles Fulltext Access 8 Pages 2008
Pluronic decorated-nanogels with temperature-responsive volume transitions, cytotoxicities, and transfection efficiencies Fulltext Access 8 Pages 2008
Surface composition and contact angle relationships for differently prepared solid dispersions Fulltext Access 8 Pages 2008
Electrospun fibers of acid-labile biodegradable polymers containing ortho ester groups for controlled release of paracetamol Fulltext Access 8 Pages 2008
Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses Fulltext Access 8 Pages 2008
Contamination of semi-solid dosage forms by leachables from aluminium tubes Fulltext Access 8 Pages 2008
Effect of chitosan structure properties and molecular weight on the intranasal absorption of tetramethylpyrazine phosphate in rats Fulltext Access 8 Pages 2008
Dissolution enhancement of the anti-HIV drug UC 781 by formulation in a ternary solid dispersion with TPGS 1000 and Eudragit E100 Fulltext Access 8 Pages 2008
Understanding the adsorption mechanism of chitosan onto poly(lactide-co-glycolide) particles Fulltext Access 8 Pages 2008
Pulmonary delivery of scutellarin solution and mucoadhesive particles in rats Fulltext Access 8 Pages 2008
Anti-tumour and immuno-modulation effects of triptolide-loaded polymeric micelles Fulltext Access 8 Pages 2008
Folate-linked lipid-based nanoparticles for synthetic siRNA delivery in KB tumor xenografts Fulltext Access 8 Pages 2008
Estrogen regulation of glucose metabolism and mitochondrial function: Therapeutic implications for prevention of Alzheimer's disease Fulltext Access 8 Pages 2008