Detecting and Identifying the Complexation of Nimodipine with Hydroxypropyl-β-Cyclodextrin Present in Tablets by Raman Spectroscopy Fulltext Access 18 Pages 2008
Determination of Particle Heterogeneity and Stability of Recombinant Adenovirus by Analytical Ultracentrifugation in CsCl Gradients Fulltext Access 18 Pages 2008
Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1) Fulltext Access 18 Pages 2008
Emerging trends in molecular recognition: Utility of weak aromatic interactions Fulltext Access 18 Pages 2008
Validation of in vitro cell culture models of the blood-brain barrier: Tightness characterization of two promising cell lines Fulltext Access 18 Pages 2008
5â²-Carbamoyl derivatives of 2â²-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: Affinity, efficacy, and selectivity for A1 receptor from different species Fulltext Access 18 Pages 2008
Synthesis of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines and comparison with their isosteric 1,2,3,4-tetrahydroisoquinolines as inhibitors of phenylethanolamine N-methyltransferase Fulltext Access 18 Pages 2008
Physical and biological considerations for the use of nonaqueous solvents in oral bioavailability enhancement Fulltext Access 18 Pages 2008
Investigation of the Impact of Annealing on Global Molecular Mobility in Glasses: Optimization for Stabilization of Amorphous Pharmaceuticals Fulltext Access 18 Pages 2008
Physical Characterization of Clostridium Difficile Toxins and Toxoids: Effect of the Formaldehyde Crosslinking on Thermal Stability Fulltext Access 18 Pages 2008
Effect of PEGylation on the Solution Conformation of Antibody Fragments Fulltext Access 18 Pages 2008
Tryptophan-containing dipeptide derivatives as potent PPARγ antagonists: Design, synthesis, biological evaluation, and molecular modeling Fulltext Access 18 Pages 2008
The novel Nâsubstituted benztropine analog GA2â50 possesses pharmacokinetic and pharmacodynamic profiles favorable for a candidate substitute medication for cocaine abuse Fulltext Access 18 Pages 2008
Thermal Inkjet Application in the Preparation of Oral Dosage Forms: Dispensing of Prednisolone Solutions and Polymorphic Characterization by Solid-State Spectroscopic Techniques Fulltext Access 18 Pages 2008
Delivery systems to increase the selectivity of antibiotics in phagocytic cells Fulltext Access 18 Pages 2008
Simulation Modelling of Human Intestinal Absorption using Caco-2 Permeability and Kinetic Solubility Data for Early Drug Discovery Fulltext Access 18 Pages 2008
Different Measures of Molecular Mobility: Comparison between Calorimetric and Thermally Stimulated Current Relaxation Times Below Tg and Correlation with Dielectric Relaxation Times Above Tg Fulltext Access 18 Pages 2008
PTD-mediated delivery of anti-cell death proteins/peptides and therapeutic enzymes Fulltext Access 18 Pages 2008
Thermodynamic studies and binding mechanisms of cell-penetrating peptides with lipids and glycosaminoglycans Fulltext Access 18 Pages 2008
Radionuclides delivery systems for nuclear imaging and radiotherapy of cancer Fulltext Access 18 Pages 2008
Cyclodextrin-based supramolecular architectures: Syntheses, structures, and applications for drug and gene delivery Fulltext Access 18 Pages 2008
Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity Fulltext Access 18 Pages 2008
In situ gelling hydrogels for pharmaceutical and biomedical applications Fulltext Access 18 Pages 2008
Discovery of new MurF inhibitors via pharmacophore modeling and QSAR analysis followed by in-silico screening Fulltext Access 18 Pages 2008
New homocamptothecins: Synthesis, antitumor activity, and molecular modeling Fulltext Access 18 Pages 2008
An efficient approach to study the toxicological effects of complex mixtures Fulltext Access 18 Pages 2008
Combined 4D‐Fingerprint and Clustering Based Membrane‐Interaction QSAR Analyses for Constructing Consensus Caco‐2 Cell Permeation Virtual Screens Fulltext Access 18 Pages 2008
Prediction of Onset of Crystallization from Experimental Relaxation Times. II. Comparison between Predicted and Experimental Onset Times Fulltext Access 18 Pages 2008
Solubility of molecular crystals: Polymorphism in the light of solubility theory Fulltext Access 18 Pages 2008
Computational design of novel fullerene analogues as potential HIV-1 PR inhibitors: Analysis of the binding interactions between fullerene inhibitors and HIV-1 PR residues using 3D QSAR, molecular docking and molecular dynamics simulations Fulltext Access 18 Pages 2008
Dexamethasone transport and ocular delivery from poly(hydroxyethyl methacrylate) gels Fulltext Access 18 Pages 2008
Synthesis and DNA-cleaving activity of lactenediynes conjugated with DNA-complexing moieties Fulltext Access 18 Pages 2008
Using an action research process in pharmacy practice research—A cooperative project between university and internship pharmacies Fulltext Access 18 Pages 2008
Novel cyclohexene derivatives as anti-sepsis agents: Synthetic studies and inhibition of NO and cytokine production Fulltext Access 18 Pages 2008
Novel 16-membered macrolides modified at C-12 and C-13 positions of midecamycin A1 and miokamycin. Part 1: Synthesis and evaluation of 12,13-carbamate and 12-arylalkylamino-13-hydroxy analogues Fulltext Access 18 Pages 2008
Systematic Studies on the Paracellular Permeation of Model Permeants and Oligonucleotides in the Rat Small Intestine with Chenodeoxycholate as Enhancer Fulltext Access 18 Pages 2008
1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor Fulltext Access 18 Pages 2008
Synthesis and in vitro properties of trimethylamine- and phosphonate-substituted carboranylporphyrins for application in BNCT Fulltext Access 18 Pages 2008
The Interaction of Heparin/polyanions with Bovine, Porcine, and Human Growth Hormone* Fulltext Access 18 Pages 2008
Discovery of sulfonylalkylamides: A new class of orally active factor Xa inhibitors Fulltext Access 18 Pages 2008
Evaluation of the Impact of Surfactant Digestion on the Bioavailability of Danazol after Oral Administration of Lipidic Self-Emulsifying Formulations to Dogs Fulltext Access 18 Pages 2008
Design and synthesis of novel leucomycin analogues modified at the C-3 position. Part II: 3-O-(3-Aryl-2-propenyl)leucomycin analogues Fulltext Access 18 Pages 2008
Ratings of journals for the dissemination of pharmacy-related social and administrative science Fulltext Access 19 Pages 2008
Therapeutic and diagnostic applications of dendrimers for cancer treatment Fulltext Access 19 Pages 2008
Advances in the synthesis of amphiphilic block copolymers via RAFT polymerization: Stimuli-responsive drug and gene delivery Fulltext Access 19 Pages 2008
Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations Fulltext Access 19 Pages 2008
Influence of Intravesicular pH Drift and Membrane Binding on the Liposomal Release of a Model Amine‐Containing Permeant Fulltext Access 19 Pages 2008
On The Biomedical Promise of Cell Penetrating Peptides: Limits Versus Prospects Fulltext Access 19 Pages 2008
Fluorinated phenylcyclopropylamines. Part 5: Effects of electron-withdrawing or -donating aryl substituents on the inhibition of monoamine oxidases A and B by 2-aryl-2-fluoro-cyclopropylamines Fulltext Access 19 Pages 2008
Amorphous cyclosporin nanodispersions for enhanced pulmonary deposition and dissolution Fulltext Access 19 Pages 2008
Enhancing intestinal drug solubilisation using lipid-based delivery systems Fulltext Access 19 Pages 2008
Novel inhibitors of 17β-hydroxysteroid dehydrogenase type 1: Templates for design Fulltext Access 19 Pages 2008
Tetramic and tetronic acids: An update on new derivatives and biological aspects Fulltext Access 19 Pages 2008
In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery Fulltext Access 19 Pages 2008
Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: Synthesis, pharmacological and molecular modeling studies Fulltext Access 19 Pages 2008
Antimicrobial and cytotoxic arylazoenamines. Part III: Antiviral activity of selected classes of arylazoenamines Fulltext Access 19 Pages 2008
Antitumor studies. Part 4: Design, synthesis, antitumor activity, and molecular docking study of novel 2-substituted 2-deoxoflavin-5-oxides, 2-deoxoalloxazine-5-oxides, and their 5-deaza analogs Fulltext Access 19 Pages 2008
Conception of myeloperoxidase inhibitors derived from flufenamic acid by computational docking and structure modification Fulltext Access 19 Pages 2008
Design and synthesis of DPP-IV inhibitors lacking the electrophilic nitrile group Fulltext Access 19 Pages 2008
Discovery of long-acting N-(cyanomethyl)-N-alkyl-l-prolinamide inhibitors of dipeptidyl peptidase IV Fulltext Access 19 Pages 2008
Design, synthesis and preliminary biological evaluation of acridine compounds as potential agents for a combined targeted chemo-radionuclide therapy approach to melanoma Fulltext Access 20 Pages 2008
Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide Fulltext Access 20 Pages 2008
Synthesis, biological evaluation, structural–activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators Fulltext Access 20 Pages 2008
5-Substituted 1H-pyrrolo[3,2-b]pyridines as inhibitors of gastric acid secretion Fulltext Access 20 Pages 2008
Synthesis and structure–activity relationships of 16-ene-22-thia-1α,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs having side chains of different sizes Fulltext Access 20 Pages 2008
Quality by Design, Part III: Study of Curing Process of Sustained Release Coated Products using NIR Spectroscopy Fulltext Access 20 Pages 2008
Application of a Two-State Kinetic Model to The Heterogeneous Kinetics of Reaction between Cysteine and Hydrogen Peroxide in Amorphous Lyophiles Fulltext Access 20 Pages 2008
Fabrication of porous substrates: A review of processes using pore forming agents in the biomaterial field Fulltext Access 20 Pages 2008
Multilayered polyelectrolyte assemblies as platforms for the delivery of DNA and other nucleic acid-based therapeutics Fulltext Access 21 Pages 2008
Pharmaceutical applications of vibrational chemical imaging and chemometrics: A review Fulltext Access 21 Pages 2008
Recent advances in the synthesis of aliphatic polyesters by ring-opening polymerization Fulltext Access 21 Pages 2008
The design of guanidinium-rich transporters and their internalization mechanisms Fulltext Access 21 Pages 2008
The potential of lipid- and polymer-based drug delivery carriers for eradicating biofilm consortia on device-related nosocomial infections Fulltext Access 21 Pages 2008
Synthesis and structure–activity relationships of thiadiazole-derivatives as potent and orally active peroxisome proliferator-activated receptors α/δ dual agonists Fulltext Access 21 Pages 2008
Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases Fulltext Access 21 Pages 2008
Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase Fulltext Access 21 Pages 2008
Alternative Measures of Lipophilicity: From Octanol-Water Partitioning to IAM Retention Fulltext Access 21 Pages 2008