Dendrimers as Drug Carriers: Applications in Different Routes of Drug Administration Fulltext Access 21 Pages 2008
Field Distribution and DNA Transport in Solid Tumors During Electric Field-Mediated Gene Delivery Fulltext Access 21 Pages 2008
Liposome Transport of Hydrophobic Drugs: Gel Phase Lipid Bilayer Permeability and Partitioning of the Lactone Form of a Hydrophobic Camptothecin, DB‐67 Fulltext Access 21 Pages 2008
Role of Thermodynamic, Molecular, and Kinetic Factors in Crystallization from the Amorphous State Fulltext Access 21 Pages 2008
Biodegradable particle formation for drug and gene delivery using supercritical fluid and dense gas Fulltext Access 22 Pages 2008
The Impact of Drying Method and Formulation on the Physical Properties and Stability of Methionyl Human Growth Hormone in the Amorphous Solid State Fulltext Access 22 Pages 2008
Challenges and emerging technologies in the immunoisolation of cells and tissues Fulltext Access 22 Pages 2008
Liposomal Delivery of Hydrophobic Weak Acids: Enhancement of Drug Retention Using a High Intraliposomal pH Fulltext Access 22 Pages 2008
Synthesis of 3,5-bis(2-indolyl)pyridine and 3-[(2-indolyl)-5-phenyl]pyridine derivatives as CDK inhibitors and cytotoxic agents Fulltext Access 22 Pages 2008
Characterization of Amorphous Solids with Weak Glass Transitions Using High Ramp Rate Differential Scanning Calorimetry Fulltext Access 22 Pages 2008
Structure–activity relationships and CoMFA of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic properties Fulltext Access 23 Pages 2008
The 2α-(3-hydroxypropyl) group as an active motif in vitamin D3 analogues as agonists of the mutant vitamin D receptor (Arg274Leu) Fulltext Access 23 Pages 2008
Investigation of DNA‐Binding Properties of Organic Molecules Using Quantitative Structure‐Activity Relationship (QSAR) Models Fulltext Access 23 Pages 2008
The Complex Inter-Relationships Between Protein Flexibility and Stability Fulltext Access 24 Pages 2008
2-Phenyl-4-piperazinylbenzimidazoles: Orally active inhibitors of the gonadotropin releasing hormone (GnRH) receptor Fulltext Access 24 Pages 2008
Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases Fulltext Access 24 Pages 2008
Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides Fulltext Access 24 Pages 2008
Recent pharmaceutical applications of raman and terahertz spectroscopies Fulltext Access 24 Pages 2008
Antibacterial activity of a novel series of 3-bromo-4-(1H-3-indolyl)-2,5-dihydro-1H-2,5-pyrroledione derivatives – An extended structure–activity relationship study Fulltext Access 24 Pages 2008
Biocompatible Microemulsions and Their Prospective Uses in Drug Delivery Fulltext Access 24 Pages 2008
Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides Fulltext Access 25 Pages 2008
Molecular imprinting within hydrogels II: Progress and analysis of the field Fulltext Access 25 Pages 2008
The gastrointestinal microbiota as a site for the biotransformation of drugs Fulltext Access 25 Pages 2008
Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARα/γ dual agonists, and X-ray crystallographic studies Fulltext Access 25 Pages 2008
Antiangiogenic Drugs: Current Knowledge and New Approaches to Cancer Therapy Fulltext Access 26 Pages 2008
Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting Fulltext Access 26 Pages 2008
Measurement of Dissociation Constants (pKa Values) of Organic Compounds by Multiplexed Capillary Electrophoresis Using Aqueous and Cosolvent Buffers* Fulltext Access 26 Pages 2008
Synthesis and structure–activity relationship studies on tryprostatin A, an inhibitor of breast cancer resistance protein Fulltext Access 26 Pages 2008
Species Differences in In Vitro and In Vivo Small Intestinal Metabolism of CYP3A Substrates Fulltext Access 26 Pages 2008
Two-Scale, Three-Phase Theory for Swelling Drug Delivery Systems. Part I: Constitutive Theory Fulltext Access 26 Pages 2008
Drying-Induced Variations in Physico-Chemical Properties of Amorphous Pharmaceuticals and Their Impact on Stability (I): Stability of a Monoclonal Antibody* Fulltext Access 26 Pages 2008
High-field solution NMR spectroscopy as a tool for assessing protein interactions with small molecule ligands Fulltext Access 26 Pages 2008
Synthesis and cannabinoid activity of 1-substituted-indole-3-oxadiazole derivatives: Novel agonists for the CB1 receptor Fulltext Access 27 Pages 2008
Enantiotropically-related polymorphs of {4-(4-chloro-3-fluorophenyl)-2-[4-(methyloxy)phenyl]-1,3-thiazol-5-yl} acetic acid: Crystal structures and multinuclear solid-state NMR Fulltext Access 27 Pages 2008
QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES Fulltext Access 27 Pages 2008
Past, Present, and Future Technologies for Oral Delivery of Therapeutic Proteins Fulltext Access 27 Pages 2008
Light Scattering as Spectroscopic Tool for the Study of Disperse Systems Useful in Pharmaceutical Sciences Fulltext Access 28 Pages 2008
Novel azalides derived from 16-membered macrolides. Part II: Isolation of the linear 9-formylcarboxylic acid and its sequential macrocyclization with an amino alcohol or an azidoamine Fulltext Access 28 Pages 2008
A Theoretical Model for Transdermal Drug Delivery from Emulsions and its Dependence upon Formulation Fulltext Access 29 Pages 2008
Microemulsions-Modern Colloidal Carrier for Dermal and Transdermal Drug Delivery Fulltext Access 29 Pages 2008
Synthesis and biological activity of imidazopyridine anticoccidial agents: Part II Fulltext Access 29 Pages 2008
Nanoparticles synthesis using supercritical fluid technology – towards biomedical applications Fulltext Access 29 Pages 2008
Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers Fulltext Access 29 Pages 2008
Polymeric Enhancers of Mucosal Epithelia Permeability: Synthesis, Transepithelial Penetration-Enhancing Properties, Mechanism of Action, Safety Issues Fulltext Access 29 Pages 2008
Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles Fulltext Access 30 Pages 2008
Formulation and Statistical Optimization of a Novel Crosslinked Polymeric AntiâTuberculosis Drug Delivery System Fulltext Access 32 Pages 2008
Intraâarticular depot formulation principles: Role in the management of postoperative pain and arthritic disorders Fulltext Access 33 Pages 2008
Inhibitors of proteases and amide hydrolases that employ an α-ketoheterocycle as a key enabling functionality Fulltext Access 34 Pages 2008
Synthesis of pharmaceutically active compounds containing a disubstituted piperidine framework Fulltext Access 35 Pages 2008
Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides Fulltext Access 38 Pages 2008
Origin of Nanodroplet Formation Upon Dissolution of an Amorphous Solid Dispersion: A Mechanistic Isotope Scrambling Study Fulltext Access 39 Pages 2008
Recent advances in selective α1-adrenoreceptor antagonists as antihypertensive agents Fulltext Access 42 Pages 2008
Pharmacokinetics and in vivo drug release rates in liposomal nanocarrier development Fulltext Access 45 Pages 2008
Fluid bed coating: The utility of dual programmable pumps for controlled gradient drug deposition on pellets Fulltext Access 4 Pages 2007
Effect of fiber length of carbon nanotubes on the absorption of erythropoietin from rat small intestine Fulltext Access 4 Pages 2007
The effect of monomers on the formulation of polymeric nanocapsules based on polyureas and polyamides Fulltext Access 4 Pages 2007
A novel texture-probe for the simultaneous and real-time measurement of swelling and erosion rates of matrix tablets Fulltext Access 4 Pages 2007
Development of sensor elements to control drug release from capsular drug delivery systems Fulltext Access 4 Pages 2007
Histological evaluation of hair follicle due to papain's depilatory effect Fulltext Access 4 Pages 2007
Study on liposomalization of zinc-coproporphyrin I as a novel drug in photodynamic therapy Fulltext Access 4 Pages 2007
Bone targeting potential of bisphosphonate-targeted liposomes: Preparation, characterization and hydroxyapatite binding in vitro Fulltext Access 4 Pages 2007
Intrapericardial administration of novel DNA formulations based on thermosensitive Poloxamer 407 gel Fulltext Access 4 Pages 2007
Fusogenic peptides enhance endosomal escape improving siRNA-induced silencing of oncogenes Fulltext Access 4 Pages 2007
Poly(amino acid)s: Promising enzymatically degradable stealth coatings for liposomes Fulltext Access 4 Pages 2007
Construction of nanoscale multicompartment liposomes for combinatory drug delivery Fulltext Access 4 Pages 2007
Prostaglandin E2 and interleukin-8 production in human epidermal keratinocytes exposed to marine lipid-based liposomes Fulltext Access 4 Pages 2007
Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins Fulltext Access 4 Pages 2007
In vitro enantioselective displacement of propranolol from protein binding sites by acetyl salicylic acid and salicylic acid Fulltext Access 4 Pages 2007
Albumin–alginate-coated microspheres: Resistance to steam sterilization and to lyophilization Fulltext Access 4 Pages 2007
Layersome: Development and optimization of stable liposomes as drug delivery system Fulltext Access 4 Pages 2007
Liposomal amphotericin B eye drops to treat fungal keratitis: Physico-chemical and formulation stability Fulltext Access 4 Pages 2007
Effects of various cyclodextrins on the stability of freezeâdried lactate dehydrogenase Fulltext Access 4 Pages 2007
A simple method for the detection of insoluble aggregates in protein formulations Fulltext Access 4 Pages 2007
The effective hard particle model provides a simple, robust, and broadly applicable description of nonideal behavior in concentrated solutions of bovine serum albumin and other nonassociating proteins Fulltext Access 4 Pages 2007
Quantitation of Crystalline Material within a Liquid Vehicle using 1H/19F CP/MAS NMR Fulltext Access 4 Pages 2007
Crystallization of Glycine During Freezing of a 40/60 w/w Sucrose/Glycine Excipient System: An Alternative to the Johnson-Mehl-Avrami (JMA) Equation for Modeling Dispersive Kinetics Fulltext Access 4 Pages 2007