Synthesis and cytotoxic evaluation of new (4,5,6,7-tetrahydro-indol-1-yl)-3-R-propionic acids and propionic acid ethyl esters generated by molecular mimicry Fulltext Access 7 Pages 2007
α-Phenyl-N-tert-butyl nitrone (PBN) derivatives: Synthesis and protective action against microvascular damages induced by ischemia/reperfusion Fulltext Access 7 Pages 2007
2D-autocorrelation descriptors for predicting cytotoxicity of naphthoquinone ester derivatives against oral human epidermoid carcinoma Fulltext Access 7 Pages 2007
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors Fulltext Access 7 Pages 2007
In vivo selection for the directed evolution of l-rhamnulose aldolase from l-rhamnulose-1-phosphate aldolase (RhaD) Fulltext Access 7 Pages 2007
Conformationally locked thiosugars as potent α-mannosidase inhibitors: Synthesis, biochemical and docking studies Fulltext Access 7 Pages 2007
Design and synthesis of pyrimido[4,5-b][1,4]benzothiazine derivatives, as potent 15-lipoxygenase inhibitors Fulltext Access 7 Pages 2007
Discovery of novel phenoxyacetic acid derivatives as antimycobacterial agents Fulltext Access 7 Pages 2007
5-Alkynyl-2′-deoxyuridines: Chromatography-free synthesis and cytotoxicity evaluation against human breast cancer cells Fulltext Access 7 Pages 2007
Synthesis and recognition of novel isonucleoside triphosphates by DNA polymerases Fulltext Access 7 Pages 2007
Clavaminols A–F, novel cytotoxic 2-amino-3-alkanols from the ascidian Clavelina phlegraea Fulltext Access 7 Pages 2007
Synthesis of isoquinuclidine analogs of chloroquine: Antimalarial and antileishmanial activity Fulltext Access 7 Pages 2007
A novel noninvasive method for assessing glutathione-conjugate efflux systems in the brain Fulltext Access 7 Pages 2007
Novel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells Fulltext Access 7 Pages 2007
Monitoring aminoglycoside-induced conformational changes in 16S rRNA through acrylamide quenching Fulltext Access 7 Pages 2007
Calculation of binding energy using BLYP/MM for the HIV-1 integrase complexed with the S-1360 and two analogues Fulltext Access 7 Pages 2007
Synthesis and antifungal activity of novel s-substituted 6-fluoro-4-alkyl(aryl)thioquinazoline derivatives Fulltext Access 7 Pages 2007
Binding of lectins to DNA micro-assemblies: Modification of nucleo-cages with lactose-conjugated psoralen Fulltext Access 7 Pages 2007
Rational design, synthesis and evaluation of (6aR∗,11bS∗)-1-(4-fluorophenyl)-4-{7-[4-(4-fluorophenyl)-4-oxobutyl]1,2,3,4,6,6a,7,11b,12,12a(RS)-decahydropyrazino[2′,1′:6,1]pyrido[3,4-b]indol-2-yl}-butan-1-one as a potential neuroleptic agent Fulltext Access 7 Pages 2007
Efficient one-pot synthesis of biologically active polysubstituted aromatic amines Fulltext Access 7 Pages 2007
The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-l-homocysteine hydrolase from Trypanosoma cruzi Fulltext Access 7 Pages 2007
Synthesis and structure–activity relationship of 7-(substituted)-aminomethyl-4-quinolone-3-carboxylic acid derivatives Fulltext Access 7 Pages 2007
Molecular probes of DNA bulges: Functional assay and spectroscopic analysis Fulltext Access 7 Pages 2007
M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: Serominic compounds Fulltext Access 7 Pages 2007
Synthesis, biological evaluation and structural determination of β-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors Fulltext Access 7 Pages 2007
Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479 Fulltext Access 7 Pages 2007
Novel selective human melanocortin-3 receptor ligands: Use of the 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one (Aba) scaffold Fulltext Access 7 Pages 2007
Indole derivatives as potent inhibitors of 5-lipoxygenase: Design, synthesis, biological evaluation, and molecular modeling Fulltext Access 7 Pages 2007
Synthesis and RET protein kinase inhibitory activity of 3-arylureidobenzylidene-indolin-2-ones Fulltext Access 7 Pages 2007
Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: Optimization of BX-517 Fulltext Access 7 Pages 2007
Heteroatom-linked indanylpyrazines are corticotropin releasing factor type-1 receptor antagonists Fulltext Access 7 Pages 2007
Synthesis of aromatic compounds containing a 1,1-dialkyl-2-trifluoromethyl group, a bioisostere of the tert-alkyl moiety Fulltext Access 7 Pages 2007
Inhibition of free radical-mediated oxidation of cellular biomolecules by carboxylated chitooligosaccharides Fulltext Access 7 Pages 2007
QSAR study of anticoccidial activity for diverse chemical compounds: Prediction and experimental assay of trans-2-(2-nitrovinyl)furan Fulltext Access 7 Pages 2007
Potent anticancer activities of novel aminophenol analogues against various cancer cell lines Fulltext Access 7 Pages 2007
Synthesis and biological activity of 2,5-diaryl-3-methylpyrimido[4,5-c]quinolin-1(2H)-one derivatives Fulltext Access 7 Pages 2007
Discovery of Helicobacter pylori shikimate kinase inhibitors: Bioassay and molecular modeling Fulltext Access 7 Pages 2007
Novel antitumor agent family of 1H-benzo[c,d]indol-2-one with flexible basic side chains: Synthesis and biological evaluation Fulltext Access 7 Pages 2007
Preparation of 5-aryl-3-alkylthio-l,2,4-triazoles and corresponding sulfones with antiinflammatory–analgesic activity Fulltext Access 7 Pages 2007
The dicationic derivatives of DBTAA: Interactions with DNA/RNA and antiproliferative effects on human cell lines Fulltext Access 7 Pages 2007
Synthesis and antioxidant activity evaluation of new 7-aryl or 7-heteroarylamino-2,3-dimethylbenzo[b]thiophenes obtained by Buchwald–Hartwig C–N cross-coupling Fulltext Access 7 Pages 2007
Design, synthesis, and evaluation of 2-aryl-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents Fulltext Access 7 Pages 2007
A simple, yet highly accurate, QSAR model captures the complement inhibitory activity of compstatin Fulltext Access 7 Pages 2007
An efficient synthesis of 3-fluoro-5-thio-xylofuranosyl nucleosides of thymine, uracil, and 5-fluorouracil as potential antitumor or/and antiviral agents Fulltext Access 7 Pages 2007
Anticancer, neuroprotective activities and computational studies of 2-amino-1,3,4-thiadiazole based compound Fulltext Access 7 Pages 2007
Synthesis of S-dialkylarsino-3-mercapto-1,2-propanediols and evaluation of their anticancer activity Fulltext Access 7 Pages 2007
Analysis of crucial structural requirements of 2-substituted pyrimido[4,5-b][1,5]oxazocines as NK1 receptor antagonist by axially chiral derivatives Fulltext Access 7 Pages 2007
A para-amino substituent on the D-ring of green tea polyphenol epigallocatechin-3-gallate as a novel proteasome inhibitor and cancer cell apoptosis inducer Fulltext Access 7 Pages 2007
Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines Fulltext Access 7 Pages 2007
Identification of antibacterial and antiviral activities of novel fused 1,2,4-triazine esters Fulltext Access 7 Pages 2007
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4â²-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists Fulltext Access 7 Pages 2007
Synthesis and antitrichinellosis activity of some bis(benzimidazol-2-yl)amines Fulltext Access 7 Pages 2007
Anti-tumor agents 255: Novel glycyrrhetinic acid–dehydrozingerone conjugates as cytotoxic agents Fulltext Access 7 Pages 2007
Synthesis and biological evaluation of cepharadiones A and B and related dioxoaporphines Fulltext Access 7 Pages 2007
Retention behavior of phenoxyacetic herbicides on a molecularly imprinted polymer with phenoxyacetic acid as a dummy template molecule Fulltext Access 7 Pages 2007
Synthesis and antiplasmodial activity of new N-[3-(4-{3-[(7-chloroquinolin-4-yl)amino]propyl}piperazin-1-yl)propyl]carboxamides Fulltext Access 7 Pages 2007
Identification of tyrosinase inhibitors from Marrubium velutinum and Marrubium cylleneum Fulltext Access 7 Pages 2007
The synthesis of α,β-unsaturated carbonyl derivatives with the ability to inhibit both glutathione S-transferase P1-1 activity and the proliferation of leukemia cells Fulltext Access 7 Pages 2007
Design, syntheses, and antitumor activity of novel chromone and aurone derivatives Fulltext Access 7 Pages 2007
Actions between neonicotinoids and key residues of insect nAChR based on an ab initio quantum chemistry study: Hydrogen bonding and cooperative π–π interaction Fulltext Access 7 Pages 2007
Amphipathic benzoic acid derivatives: Synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC Fulltext Access 7 Pages 2007
On the applicability of QSAR for recognition of miRNA bioorganic structures at early stages of organism and cell development: Embryo and stem cells Fulltext Access 7 Pages 2007
The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum Fulltext Access 7 Pages 2007
RETRACTED: Colon-specific, mutual azo prodrug of 5-aminosalicylic acid with l-tryptophan: Synthesis, kinetic studies and evaluation of its mitigating effect in trinitrobenzenesulfonic acid-induced colitis in rats Fulltext Access 7 Pages 2007
Photodynamic activity of water-soluble phthalocyanine zinc(II) complexes against pathogenic microorganisms Fulltext Access 7 Pages 2007
Stereoselective synthesis of β-1-C-substituted 1,4-dideoxy-1,4-imino-d-galactitols and evaluation as UDP-galactopyranose mutase inhibitors Fulltext Access 7 Pages 2007
Hydrate modifications of the non-steroidal anti-inflammatory drug diclofenac sodium: Solid-state characterisation of a trihydrate form Fulltext Access 7 Pages 2007
Alkaloid profiling in crude and processed Strychnos nux-vomica seeds by matrix-assisted laser desorption/ionization-time of flight mass spectrometry Fulltext Access 7 Pages 2007
Prediction of binding for a kind of non-peptic HCV NS3 serine protease inhibitors from plants by molecular docking and MM-PBSA method Fulltext Access 7 Pages 2007
Synthesis and structure–activity relationships of novel warfarin derivatives Fulltext Access 7 Pages 2007
Synthesis and evaluation of 2′,4′,6′-trihydroxychalcones as a new class of tyrosinase inhibitors Fulltext Access 7 Pages 2007
Synthesis and in vitro evaluation of targeted tetracycline derivatives: Effects on inhibition of matrix metalloproteinases Fulltext Access 7 Pages 2007
Structural advantage of dendritic poly(l-lysine) for gene delivery into cells Fulltext Access 7 Pages 2007
Selection and syntheses of tentacle type peptides as 'artificial' lectins against various cell-surface carbohydrates Fulltext Access 7 Pages 2007
Synthesis of 6-chloroisoquinoline-5,8-diones and pyrido[3,4-b]phenazine-5,12-diones and evaluation of their cytotoxicity and DNA topoisomerase II inhibitory activity Fulltext Access 7 Pages 2007
Synthesis and characterization of styrylchromone derivatives as β-amyloid imaging agents Fulltext Access 7 Pages 2007
Identification of some novel AHAS inhibitors via molecular docking and virtual screening approach Fulltext Access 7 Pages 2007
Isoindolo[2,1-c]benzo[1,2,4]triazines: A new ring system with antiproliferative activity Fulltext Access 7 Pages 2007
1-Methylpyridinium-4-(4-phenylmethanethiosulfonate) iodide, MTS-MPP+, a novel scanning cysteine accessibility method (SCAM) reagent for monoamine transporter studies Fulltext Access 7 Pages 2007
Synthesis and antitumor activities of a series of novel quinoxalinhydrazides Fulltext Access 7 Pages 2007
Synthesis and pharmacological evaluation of some 3-phenyl-2-substituted-3H-quinazolin-4-one as analgesic, anti-inflammatory agents Fulltext Access 7 Pages 2007
Gas-phase transfer of polymer cross-linking agents and by-products to solid oral pharmaceuticals Fulltext Access 7 Pages 2007
Synthesis and cytotoxic activity of pyrazino[1,2-b]-isoquinolines, 1-(3-isoquinolyl)isoquinolines, and 6,15-iminoisoquino[3,2-b]-3-benzazocines Fulltext Access 7 Pages 2007
Synthesis and biological activities of analogs of d-glucosyl-l-tyrosine, a humoral factor that stimulates transcription of the acyl-CoA binding protein in the pheromone gland of the Silkmoth, Bombyx mori Fulltext Access 7 Pages 2007
New oxime reactivators connected with CH2O(CH2)nOCH2 linker and their reactivation potency for organophosphorus agents-inhibited acetylcholinesterase Fulltext Access 7 Pages 2007
Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell Fulltext Access 7 Pages 2007
Syntheses of immunomodulating androstanes and stigmastanes: Comparison of their TNF-α inhibitory activity Fulltext Access 7 Pages 2007
Anti-AIDS agents 66: Syntheses and anti-HIV activity of phenolic and aza 3′,4′-di-O-(−)-camphanoyl-(+)-cis-khellactone (DCK) derivatives Fulltext Access 7 Pages 2007
Synthesis and anticonvulsant evaluation of 4-(4-alkoxylphenyl)-3-ethyl-4H-1,2,4-triazoles as open-chain analogues of 7-alkoxyl-4,5-dihydro[1,2,4]triazolo[4,3-a]quinolines Fulltext Access 7 Pages 2007
Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents Fulltext Access 7 Pages 2007
Carbonic anhydrase activators: The first activation study of the human secretory isoform VI with amino acids and amines Fulltext Access 7 Pages 2007