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Daneshyari Pharmaceutical Science Journas Latest Articles

Pharmaceutical Science Research Articles

Proteomic analysis identifies candidate proteins associated with distant recurrences in breast cancer after adjuvant chemotherapy
Fulltext Access 8 Pages 2007
Synthesis, antiviral and antitumor activity of 2-substituted-5-amidino-benzimidazoles
Fulltext Access 8 Pages 2007
Synthesis, antiproliferative, and antiplatelet activities of oxime- and amide-containing quinolin-2(1H)-one derivatives
Fulltext Access 8 Pages 2007
A versatile strategy for the synthesis of crown ether-bearing heterocycles: Discovery of calcium-selective fluoroionophore
Fulltext Access 8 Pages 2007
Antioxidant properties and free radical-scavenging reactivity of a family of hydroxynaphthalenones and dihydroxyanthracenones
Fulltext Access 8 Pages 2007
Synthesis, DNA binding, and cytotoxicity studies of pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates
Fulltext Access 8 Pages 2007
Stability experiments in human urine with EO9 (apaziquone): A novel anticancer agent for the intravesical treatment of bladder cancer
Fulltext Access 8 Pages 2007
Advantages of using tetrahydrofuran–water as mobile phases in the quantitation of cyclosporin A in monkey and rat plasma by liquid chromatography–tandem mass spectrometry
Fulltext Access 8 Pages 2007
Stereospecific high-performance liquid chromatographic analysis of eriodictyol in urine
Fulltext Access 8 Pages 2007
High performance liquid chromatographic determination of etofibrate and its hydrolysis products
Fulltext Access 8 Pages 2007
Acid–base equilibrium of puerarin in CTAB micelles
Fulltext Access 8 Pages 2007
Capillary electrophoresis analysis of hydrolysis, isomerization and enantiomerization of aspartyl model tripeptides in acidic and alkaline solution
Fulltext Access 8 Pages 2007
Development of gas chromatography–mass spectrometry with microwave distillation and simultaneous solid-phase microextraction for rapid determination of volatile constituents in ginger
Fulltext Access 8 Pages 2007
The discovery of substituted 4-(3-hydroxyanilino)-quinolines as potent RET kinase inhibitors
Fulltext Access 8 Pages 2007
Biotransformation of letrozole in rat liver microsomes: Effects of gender and tamoxifen
Fulltext Access 8 Pages 2007
LC–MS/MS method for simultaneous determination of viramidine and ribavirin levels in monkey red blood cells
Fulltext Access 8 Pages 2007
LC–MS determination and relative bioavailability of doxazosin mesylate tablets in healthy Chinese male volunteers
Fulltext Access 8 Pages 2007
Complexation study of cinalukast and montelukast with cyclodextrines
Fulltext Access 8 Pages 2007
Development of a slurry introduction method for multi-element analysis of antibiotics by inductively coupled plasma atomic emission spectrometry using various types of spray chamber and nebulizer configurations
Fulltext Access 8 Pages 2007
Nature of the main contaminant in the drug primaquine diphosphate: SFC and SFC–MS methods of analysis
Fulltext Access 8 Pages 2007
Quantification of olanzapine polymorphs using powder X-ray diffraction technique
Fulltext Access 8 Pages 2007
High-performance liquid chromatographic method for the simultaneous determination of 24 fragrance allergens to study scented products
Fulltext Access 8 Pages 2007
Comparison of liquid chromatography and capillary electrophoresis methods for quantification of sodium residuals
Fulltext Access 8 Pages 2007
Development and validation of a sensitive liquid chromatographic method for the analysis of a novel radioprotectant: ON 01210.Na
Fulltext Access 8 Pages 2007
Characterization of polymethoxylated flavones in Fructus aurantii by liquid chromatography with atmospheric pressure chemical ionization combined with tandem mass spectrometry
Fulltext Access 8 Pages 2007
Evaluation of in vitro aldose redutase inhibitory activity of 5-arylidene-2,4-thiazolidinediones
Fulltext Access 8 Pages 2007
Carbonic anhydrase activators: l-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV
Fulltext Access 8 Pages 2007
Quantitative structure–activity relationship (QSAR) of indoloacetamides as inhibitors of human isoprenylcysteine carboxyl methyltransferase
Fulltext Access 8 Pages 2007
Pharmacophoric features of Pseudomonas aeruginosa deacetylase LpxC inhibitors: An electronic and structural analysis
Fulltext Access 8 Pages 2007
Diazenedicarboxamides as inhibitors of d-alanine-d-alanine ligase (Ddl)
Fulltext Access 8 Pages 2007
Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: Synthesis, in vitro profile, molecular modeling studies, and in vivo experiments
Fulltext Access 8 Pages 2007
From selective substrate analogue factor Xa inhibitors to dual inhibitors of thrombin and factor Xa. Part 3
Fulltext Access 8 Pages 2007
The discovery of potent, selective, and orally bioavailable hNK1 antagonists derived from pyrrolidine
Fulltext Access 8 Pages 2007
Enantiopure five-membered cyclicdiamine derivatives as potent and selective inhibitors of factor Xa. Improving in vitro metabolic stability via core modifications
Fulltext Access 8 Pages 2007
Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing heterobiaryl carboxylic acids
Fulltext Access 8 Pages 2007
Design, structure–activity relationship, and pharmacokinetic profile of pyrazole-based indoline factor Xa inhibitors
Fulltext Access 8 Pages 2007
Synthesis and structure–activity relationship of 3,4′-bispyridinylethylenes: Discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer
Fulltext Access 8 Pages 2007
New highly hydrosoluble and not self-aggregated perylene derivatives with three and four polar side-chains as G-quadruplex telomere targeting agents and telomerase inhibitors
Fulltext Access 8 Pages 2007
Reliable HPLC method for therapeutic drug monitoring of frequently prescribed tricyclic and nontricyclic antidepressants
Fulltext Access 8 Pages 2007
Microwave prompted multigram synthesis, structural determination, and photo-antiproliferative activity of fluorinated 4-hydroxyquinolinones
Fulltext Access 8 Pages 2007
Synthesis and structure–activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1)
Fulltext Access 8 Pages 2007
Pharmacophore modeling and in silico screening for new KDR kinase inhibitors
Fulltext Access 8 Pages 2007
Probing acid replacements of thiophene PTP1B inhibitors
Fulltext Access 8 Pages 2007
Discovery of a novel small molecule binding site of human survivin
Fulltext Access 8 Pages 2007
Synthesis and SAR of thiophene containing kinesin spindle protein (KSP) inhibitors
Fulltext Access 8 Pages 2007
Novel inhibitors of VEGF receptors-1 and -2 based on azole-5-carboxamide templates
Fulltext Access 8 Pages 2007
Synthesis and biological evaluation of 4′-(6,7-disubstituted-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors
Fulltext Access 8 Pages 2007
5-((4-Aminopiperidin-1-yl)methyl)pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases
Fulltext Access 8 Pages 2007
Pyrimidine benzamide-based thrombopoietin receptor agonists
Fulltext Access 8 Pages 2007
Discovery of 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2′-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors
Fulltext Access 8 Pages 2007
Simultaneously determination of five ginsenosides in rabbit plasma using solid-phase extraction and HPLC/MS technique after intravenous administration of ‘SHENMAI’ injection
Fulltext Access 8 Pages 2007
Validation of a method for the simultaneous determination of four schisandra lignans in the raw herb and commercial dried aqueous extracts of Schisandra chinensis (Wu Wei Zi) by RP-LC with DAD
Fulltext Access 8 Pages 2007
Validation of a sensitive LC/MS/MS method for simultaneous quantitation of flupentixol and melitracen in human plasma
Fulltext Access 8 Pages 2007
Electrochemical and spectroscopic characterization of the interaction between DNA and Cu(II)–naringin complex
Fulltext Access 8 Pages 2007
Analysis of guazatine mixture by LC and LC–MS and antimycotic activity determination of principal components
Fulltext Access 8 Pages 2007
A highly sensitive resonance Rayleigh scattering method for the determination of bleomycinA5 and bleomycinA2 with some halofluorescein dyes
Fulltext Access 8 Pages 2007
HPLC method for the determination of fluvoxamine in human plasma and urine for application to pharmacokinetic studies
Fulltext Access 8 Pages 2007
NMR analysis of ion pair formation between timolol and sorbic acid in ophthalmic preparations
Fulltext Access 8 Pages 2007
Identification and characterization of potential impurities of rabeprazole sodium
Fulltext Access 8 Pages 2007
Isolation and characterization of degradation impurities in docetaxel drug substance and its formulation
Fulltext Access 8 Pages 2007
LC and LC-MS study of stress decomposition behaviour of isoniazid and establishment of validated stability-indicating assay method
Fulltext Access 8 Pages 2007
A simple and reliable procedure for the determination of psychoactive drugs in oral fluid by gas chromatography–mass spectrometry
Fulltext Access 8 Pages 2007
Development of a liquid chromatography/tandem mass spectrometry method for the quantitation of acetylcholine and related neurotransmitters in brain microdialysis samples
Fulltext Access 8 Pages 2007
Selective adsorption of norfloxacin in aqueous media by an imprinted polymer based on hydrophobic and electrostatic interactions
Fulltext Access 8 Pages 2007
Validated HPLC–MS/MS method for determination of quetiapine in human plasma
Fulltext Access 8 Pages 2007
System suitability in bioanalytical LC/MS/MS
Fulltext Access 8 Pages 2007
Investigation of sorbic acid volatile degradation products in pharmaceutical formulations using static headspace gas chromatography
Fulltext Access 8 Pages 2007
Development and integration of an immunoaffinity monolithic disk for the on-line solid-phase extraction and HPLC determination with fluorescence detection of aflatoxin B1 in aqueous solutions
Fulltext Access 8 Pages 2007
Structural characterization of PEGylated rHuG-CSF and location of PEG attachment sites
Fulltext Access 8 Pages 2007
Determination of lopinavir cerebral spinal fluid and plasma ultrafiltrate concentrations by liquid chromatography coupled to tandem mass spectrometry
Fulltext Access 8 Pages 2007
Evaluation of impurities level of perindopril tert-butylamine in tablets
Fulltext Access 8 Pages 2007
Standardization and stability studies of neuroprotective lipid soluble fraction obtained from Curcuma longa
Fulltext Access 8 Pages 2007
Validation of a dissolution method with HPLC analysis for lasofoxifene tartrate low dose tablets
Fulltext Access 8 Pages 2007
Degradation of high-molar-mass hyaluronan by an oxidative system comprising ascorbate, Cu(II), and hydrogen peroxide: Inhibitory action of antiinflammatory drugs—Naproxen and acetylsalicylic acid
Fulltext Access 8 Pages 2007
Potential employment of non-silica-based stationary phases in pharmaceutical analysis
Fulltext Access 8 Pages 2007
UV–vis and FTIR–ATR spectroscopic techniques to study the inclusion complexes of genistein with β-cyclodextrins
Fulltext Access 8 Pages 2007
Quantification of 13C pyruvate and 13C lactate in dog blood by reversed-phase liquid chromatography–electrospray ionization mass spectrometry after derivatization with 3-nitrophenylhydrazine
Fulltext Access 8 Pages 2007
Is HPLC assay for drug substance a useful quality control attribute?
Fulltext Access 8 Pages 2007
Characterization of acid–base properties of unstable drugs using a continuous-flow system with UV–vis spectrophotometric detection
Fulltext Access 8 Pages 2007
The application of microbore UPLC/oa-TOF-MS and 1H NMR spectroscopy to the metabonomic analysis of rat urine following the intravenous administration of pravastatin
Fulltext Access 8 Pages 2007
Structural identification and characterization of impurities in ceftizoxime sodium
Fulltext Access 8 Pages 2007
Reduction of carry-over in column-switching HPLC/MS system with automated system washing procedure for highly sensitive direct analysis of donepezil in dog plasma
Fulltext Access 8 Pages 2007
Development and validation of HPLC methods for the determination of potential extractables from elastomeric stoppers in the presence of a complex surfactant vehicle used in the preparation of parenteral drug products
Fulltext Access 8 Pages 2007
Increasing conclusiveness of metabonomic studies by cheminformatic preprocessing of capillary electrophoretic data on urinary nucleoside profiles
Fulltext Access 8 Pages 2007
Conformational mobility of immobilized proteins
Fulltext Access 8 Pages 2007
Simultaneous determination of homoeriodictyol-7-O-β-d-Glccopyranoside and its metabolite homoeriodictyol in rat tissues and urine by liquid chromatography–mass spectrometry
Fulltext Access 8 Pages 2007
Buprenorphine assay and plasma concentration monitoring in HIV-infected substance users
Fulltext Access 8 Pages 2007
Investigation on response of the metabolites in tricarboxylic acid cycle of Escherichi coli and Pseudomonas aeruginosa to antibiotic perturbation by capillary electrophoresis
Fulltext Access 8 Pages 2007
A comparative study of capillary zone electrophoresis and pH-potentiometry for determination of dissociation constants
Fulltext Access 8 Pages 2007
Analysis of underivatized gentamicin by capillary electrophoresis with UV detection
Fulltext Access 8 Pages 2007
Electrochemical monitoring of piroxicam in different pharmaceutical forms with multi-walled carbon nanotubes paste electrode
Fulltext Access 8 Pages 2007
Improving the detection limits of antispasmodic drugs electrodes by using modified membrane sensors with inner solid contact
Fulltext Access 8 Pages 2007
Simultaneous determination of desloratadine and its active metabolite 3-hydroxydesloratadine in human plasma by LC/MS/MS and its application to pharmacokinetics and bioequivalence
Fulltext Access 8 Pages 2007
Conventional and planar chip sensors for potentiometric assay of uric acid in biological fluids using flow injection analysis
Fulltext Access 8 Pages 2007
Simultaneous quantitative analysis of oxcarbazepine and 10,11-dihydro-10-hydroxycarbamazepine in human plasma by liquid chromatography–electrospray tandem mass spectrometry
Fulltext Access 8 Pages 2007
Enhancement of dissolution amount and in vivo bioavailability of itraconazole by complexation with β-cyclodextrin using supercritical carbon dioxide
Fulltext Access 8 Pages 2007
Qualitative and quantitative determination of ten alkaloids in traditional Chinese medicine Corydalis yanhusuo W.T. Wang by LC–MS/MS and LC–DAD
Fulltext Access 8 Pages 2007
Enantiomeric separation of 2-aryloxyalkyl- and 2-arylalkyl-2-aryloxyacetic acids on a Penicillin G Acylase-based chiral stationary phase: Influence of the chemical structure on retention and enantioselectivity
Fulltext Access 8 Pages 2007
Development and validation of a liquid chromatography–mass spectrometry assay for the determination of pyronaridine in human blood for application to clinical pharmacokinetic studies
Fulltext Access 8 Pages 2007
β-Blockers and benzodiazepines location in SDS and bile salt micellar systems: An ESR study
Fulltext Access 8 Pages 2007
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