Mahuang decoction mitigates airway inflammation and regulates IL-21/STAT3 signaling pathway in rat asthma model Fulltext Access 26 Pages 2018
Saikosaponin A inhibits compound 48/80-induced pseudo-allergy via the Mrgprx2 pathway in vitro and in vivo Fulltext Access 26 Pages 2018
Inhibition of microRNA-505 suppressed MPP+â¯-induced cytotoxicity of SHSY5Y cells in an in vitro Parkinson's disease model Fulltext Access 26 Pages 2018
The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC) Fulltext Access 26 Pages 2018
Scopoletin inhibits α-glucosidase in vitro and alleviates postprandial hyperglycemia in mice with diabetes Fulltext Access 26 Pages 2018
Hesperidin suppresses the migration and invasion of non-small cell lung cancer cells by inhibiting the SDF-1/CXCR-4 pathway Fulltext Access 26 Pages 2018
The protective effect of Hif3a RNA interference and HIF-prolyl hydroxylase inhibition on cardiomyocytes under anoxia-reoxygenation Fulltext Access 26 Pages 2018
The orphan nuclear receptor NR4A1 attenuates oxidative stress-induced β cells apoptosis via up-regulation of glutathione peroxidase 1 Fulltext Access 26 Pages 2018
Effects of Baoyuan decoction, a traditional Chinese medicine formula, on the activities and mRNA expression of seven CYP isozymes in rats Fulltext Access 26 Pages 2018
Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1α/VEGF pathway Fulltext Access 26 Pages 2018
How to effectively treat acute leukemia patients bearing MLL-rearrangements ? Fulltext Access 26 Pages 2018
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice Fulltext Access 26 Pages 2018
Bioassay-guided isolation of active substances from Semen Torreyae identifies two new anthelmintic compounds with novel mechanism of action Fulltext Access 26 Pages 2018
Anti-inflammatory activities and potential mechanisms of phenolic acids isolated from Salvia miltiorrhiza f. alba roots in THP-1 macrophages Fulltext Access 26 Pages 2018
Assessment of genotoxic activity of oleoresins and leaves extracts of six Copaifera species for prediction of potential human risks Fulltext Access 26 Pages 2018
In vitro anti-diabetic effect of flavonoids and pheophytins from Allophylus cominia Sw. on the glucose uptake assays by HepG2, L6, 3T3-L1 and fat accumulation in 3T3-L1 adipocytes Fulltext Access 26 Pages 2018
Proanthocyanidin polymeric tannins from Stryphnodendron adstringens are effective against Candida spp. isolates and for vaginal candidiasis treatment Fulltext Access 26 Pages 2018
Morinda officinalis How. - A comprehensive review of traditional uses, phytochemistry and pharmacology Fulltext Access 26 Pages 2018
Comparison of two Jatropha species (Euphorbiaceae) used popularly to treat snakebites in Northeastern Brazil: Chemical profile, inhibitory activity against Bothrops erythromelas venom and antibacterial activity Fulltext Access 26 Pages 2018
Salinomycin-induced autophagy blocks apoptosis via the ATG3/AKT/mTOR signaling axis in PC-3 cells Fulltext Access 26 Pages 2018
The role of cathepsin B in autophagy during obesity: A systematic review Fulltext Access 26 Pages 2018
Inhibiting autophagy promotes collagen degradation by regulating matrix metalloproteinases in pancreatic stellate cells Fulltext Access 26 Pages 2018
Evaluation of antioxidant potencial of novel CaAl and NiAl layered double hydroxides loaded with olanzapine Fulltext Access 26 Pages 2018
Effects and mechanism of the HECT study (hybrid exercise-cognitive trainings) in mild ischemic stroke with cognitive decline: fMRI for brain plasticity, biomarker and behavioral analysis Fulltext Access 26 Pages 2018
Exploring the Q-marker of “sweat soaking method” processed radix Wikstroemia indica: Based on the “effect-toxicity-chemicals” study Fulltext Access 26 Pages 2018
Homoeriodictyol protects human endothelial cells against oxidative insults through activation of Nrf2 and inhibition of mitochondrial dysfunction Fulltext Access 26 Pages 2018
Lower glycemic indices and lipid profile among type 2 diabetes mellitus patients who received novel dose of Silybum marianum (L.) Gaertn. (silymarin) extract supplement: A Triple-blinded randomized controlled clinical trial Fulltext Access 26 Pages 2018
Activation of PI3K/Akt pathway mediated by estrogen receptors accounts for estrone-induced vascular activation of cGMP signaling Fulltext Access 26 Pages 2018
Total phenolic and flavonoid contents and antihypertensive effect of the crude extract and fractions of Calamintha vulgaris Fulltext Access 26 Pages 2018
Pharmacokinetics and cytotoxic study of euphol from Euphorbia umbellata (Bruyns) Pax latex Fulltext Access 26 Pages 2018
Cholinesterase-inhibitory effect and in silico analysis of alkaloids from bulbs of Hieronymiella species Fulltext Access 26 Pages 2018
Intradermal and intranasal immunizations with oligomeric middle layer rotavirus VP6 induce Th1, Th2 and Th17â¯T cell subsets and CD4+ T lymphocytes with cytotoxic potential Fulltext Access 26 Pages 2018
Carbon monoxide releasing molecule A-1 attenuates acetaminophen-mediated hepatotoxicity and improves survival of mice by induction of Nrf2 and related genes Fulltext Access 26 Pages 2018
CrossâCultural Analysis of Medicinal Plants commonly used in Ethnoveterinary Practices at South Waziristan Agency and Bajaur Agency, Federally Administrated Tribal Areas (FATA), Pakistan Fulltext Access 26 Pages 2018
Farnesoid X receptor agonist obeticholic acid inhibits renal inflammation and oxidative stress during lipopolysaccharide-induced acute kidney injury Fulltext Access 27 Pages 2018
Arenobufagin is a novel isoform-specific probe for sensing human sulfotransferase 2A1 Fulltext Access 27 Pages 2018
Sesquiterpene lactone from Artemisia argyi induces gastric carcinoma cell apoptosis via activating NADPH oxidase/reactive oxygen species/mitochondrial pathway Fulltext Access 27 Pages 2018
Suramin is a novel competitive antagonist selective to α1β2γ2 GABAA over Ï1 GABAC receptors Fulltext Access 27 Pages 2018
Drug metabolism and pharmacokinetic strategies for oligonucleotide- and mRNA-based drug development Fulltext Access 27 Pages 2018
Nitric oxide alterations in cardiovascular system of rats with Parkinsonism induced by 6-OHDA and submitted to previous exercise Fulltext Access 27 Pages 2018
Sirtuinâ1 protects hair follicle stem cells from TNFα-mediated inflammatory stress via activating the MAPK-ERK-Mfn2 pathway Fulltext Access 27 Pages 2018
Precision medicine approach: Empagliflozin for diabetic cardiomyopathy in mice with aldehyde dehydrogenase (ALDH) 2â¯*â¯2 mutation, a specific genetic mutation in millions of East Asians Fulltext Access 27 Pages 2018
Skin nociceptive block with pramoxine delivery by subcutaneous injection in rats Fulltext Access 27 Pages 2018
Acute high-intensity interval exercise induces comparable levels of circulating cell-free DNA and Interleukin-6 in obese and normal-weight individuals Fulltext Access 27 Pages 2018
Induction of beige adipocytes by naturally occurring β3-adrenoceptor agonist p-synephrine Fulltext Access 27 Pages 2018
Thermosensitive chitosan/phosphate hydrogel-composites fortified with Ag versus Ag@Pd for biomedical applications Fulltext Access 27 Pages 2018
Therapeutic vaccine against IL-1β improved glucose control in a mouse model of type 2 diabetes Fulltext Access 27 Pages 2018
Post-translational modifications at the ATP-positioning G-loop that regulate protein kinase activity Fulltext Access 27 Pages 2018
Dosing ribavirin in hepatitis E-infected solid organ transplant recipients Fulltext Access 27 Pages 2018
Biosensing estrogenic endocrine disruptors in human blood and urine: A RAPID cell-free protein synthesis approach Fulltext Access 27 Pages 2018
Safety and efficacy of nintedanib in idiopathic pulmonary fibrosis: A real-life observational study in Greece Fulltext Access 27 Pages 2018
Intracellular calcium and NF-kB regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes Fulltext Access 27 Pages 2018
Implication of STARD5 and cholesterol homeostasis disturbance in the endoplasmic reticulum stress-related response induced by pro-apoptotic aminosteroid RM-133 Fulltext Access 27 Pages 2018
Behavioral effects of combined morphine and MK-801 administration to the locus coeruleus of a rat neuropathic pain model Fulltext Access 27 Pages 2018
Genetic imaging study with [Tc-99m] TRODAT-1 SPECT in adolescents with ADHD using OROS-methylphenidate Fulltext Access 27 Pages 2018
Modulatory role of conspecific alarm substance on aggression and brain monoamine oxidase activity in two zebrafish populations Fulltext Access 27 Pages 2018
The effects of vitamin D and probiotic co-supplementation on mental health parameters and metabolic status in type 2 diabetic patients with coronary heart disease: A randomized, double-blind, placebo-controlled trial Fulltext Access 27 Pages 2018
Evaluation of Transdermal Drug Permeation as Modulated by Lipoderm and Pluronic Lecithin Organogel Fulltext Access 27 Pages 2018
A flavonoid compound library screen revealed potent antiviral activity of plant-derived flavonoids on human enterovirus A71 replication Fulltext Access 27 Pages 2018
An in silico-designed flavone derivative, 6-fluoro-4â²-hydroxy-3â²,5â²-dimetoxyflavone, has a greater anti-human cytomegalovirus effect than ganciclovir in infected cells Fulltext Access 27 Pages 2018
Antifungal drug ciclopirox olamine reduces HSV-1 replication and disease in mice Fulltext Access 27 Pages 2018
St John's wort (Hypericum perforatum) products - an assessment of their authenticity and quality Fulltext Access 27 Pages 2018
Enhanced liver-targeting via coadministration of 10-Hydroxycamptothecin polymeric micelles with vinegar baked Radix Bupleuri Fulltext Access 27 Pages 2018
Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-F10 cells by inducing senescence Fulltext Access 27 Pages 2018
Methodology for controlled administration of smoked synthetic cannabinoids JWH-018 and JWH-073 Fulltext Access 27 Pages 2018
Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to repair the genome and improve stroke recovery Fulltext Access 27 Pages 2018
Tat-enhanced delivery of the C terminus of HDAg-L inhibits assembly and secretion of hepatitis D virus Fulltext Access 27 Pages 2018
Genome-wide characterization and analysis of bHLH transcription factors in Panax ginseng Fulltext Access 27 Pages 2018
The potential mechanism for Hydroxysafflor yellow A attenuating blood-brain barrier dysfunction via tight junction signaling pathways excavated by an integrated serial affinity chromatography and shotgun proteomics analysis approach Fulltext Access 27 Pages 2018
Icariside II, a PDE5 inhibitor from Epimedium brevicornum, promotes neuron-like pheochromocytoma PC12 cell proliferation via activating NO/cGMP/PKG pathway Fulltext Access 27 Pages 2018
Dopamine D3 receptor partial agonist LS-3-134 attenuates cocaine-motivated behaviors Fulltext Access 27 Pages 2018
Candesartan, angiotensin II type 1 receptor blocker is able to relieve age-related cognitive impairment Fulltext Access 27 Pages 2018
Mitigative role of garlic and vitamin E against cytotoxic, genotoxic, and apoptotic effects of lead acetate and mercury chloride on WI-38 cells Fulltext Access 27 Pages 2018
Multi-targeting effects of a new synthetic molecule (JM-20) in experimental models of cerebral ischemia Fulltext Access 27 Pages 2018
Autophagy is a major mechanism for the dual effects of curcumin on renal cell carcinoma cells Fulltext Access 27 Pages 2018
The essential oil from Citrus limetta Risso peels alleviates skin inflammation: In-vitro and in-vivo study Fulltext Access 27 Pages 2018
Euphorbia lunulata extract acts on multidrug resistant gastric cancer cells to inhibit cell proliferation, migration and invasion, arrest cell cycle progression, and induce apoptosis Fulltext Access 27 Pages 2018
Bai Hu Tang, Si Ni Tang, and Xue Bi Tang amplify pro-inflammatory activities and reduce apoptosis in endothelial cells in a cell culture model of sepsis Fulltext Access 27 Pages 2018
Artepillin C, drupanin, aromadendrin-4â²-O-methyl-ether and kaempferide from Brazilian green propolis promote gastroprotective action by diversified mode of action Fulltext Access 27 Pages 2018
Antidiabetic and antiobesity effects of SGLT2 inhibitor ipragliflozin in type 2 diabetic mice fed sugar solution Fulltext Access 27 Pages 2018
Alpha-asarone attenuates depression-like behavior in nicotine-withdrawn mice: Evidence for the modulation of hippocampal pCREB levels during nicotine-withdrawal Fulltext Access 27 Pages 2018
Etizolam attenuates the reduction in cutaneous temperature induced in mice by exposure to synthetic predator odor Fulltext Access 27 Pages 2018
The potential role of glucokinase activator SHP289-04 in anti-diabetes and hepatic protection Fulltext Access 27 Pages 2018
The relationship of plasma miR-503 and coronary collateral circulation in patients with coronary artery disease Fulltext Access 27 Pages 2018
A novel pharmacodynamic model in rats for preventing vascular dementia from maintaining neurovascular coupling sensitivity Fulltext Access 27 Pages 2018
Foenumoside B isolated from Lysimachia foenum-graecum extract suppresses LPS-induced inflammatory response via NF-κB/AP-1 inactivation in murine macrophages and in endotoxin-induced shock model Fulltext Access 27 Pages 2018
Protective effect of propofol on ischemia-reperfusion injury detected by HPLC-MS/MS targeted metabolic profiling Fulltext Access 27 Pages 2018
Pharmacological rescue of mutated Kv3.1 ion-channel linked to progressive myoclonus epilepsies Fulltext Access 27 Pages 2018
Investigations into the carbonic anhydrase inhibition of COS-releasing donor core motifs Fulltext Access 27 Pages 2018
Resistin facilitates VEGF-C-associated lymphangiogenesis by inhibiting miR-186 in human chondrosarcoma cells Fulltext Access 27 Pages 2018
The macrophage heme-heme oxygenase-1 system and its role in inflammation Fulltext Access 27 Pages 2018
PTEN/FLJ10540/PI3K/Akt cascade in experimental brain stem death: A newfound role for a classical tumorigenic signaling pathway Fulltext Access 27 Pages 2018