Tumor inhibitory effects of intravesical Ganoderma lucidum instillation in the syngeneic orthotopic MB49/C57 bladder cancer mice model Fulltext Access 27 Pages 2018
A thirteen-week oral toxicity study of So-ochim-tang-gami-bang, a traditional Korean medicine, in Sprague-Dawley rats Fulltext Access 27 Pages 2018
Tetraglochin andina Ciald.: A medicinal plant from the Argentinean highlands with potential use in vaginal candidiasis Fulltext Access 27 Pages 2018
Antinociceptive activity of Inula britannica L. and patuletin: In vivo and possible mechanisms studies Fulltext Access 27 Pages 2018
Patchouli alcohol isolated from Pogostemon cablin mediates endothelium-independent vasorelaxation by blockade of Ca2+ channels in rat isolated thoracic aorta Fulltext Access 27 Pages 2018
Ethnobotany, phytochemistry and pharmacology of Arctotis arctotoides (L.f.) O. Hoffm.: A review Fulltext Access 27 Pages 2018
Metabolic profiling and correlation analysis for the determination of killer compounds of proliferating and clonogenic HRT-18 colon cancer cells from Lafoensia pacari Fulltext Access 27 Pages 2018
Cardio-protection of ultrafine granular powder for Salvia miltiorrhiza Bunge against myocardial infarction Fulltext Access 27 Pages 2018
Safety assessment of Morus nigra L. leaves: Acute and subacute oral toxicity studies in Wistar rats Fulltext Access 27 Pages 2018
Chemical composition and antimicrobial activity of Myrcianthes fragrans essential oil, a natural aromatizer of the traditional Ecuadorian beverage colada morada Fulltext Access 27 Pages 2018
Material basis research for Huangqi Jianzhong Tang against chronic atrophic gastritis rats through integration of urinary metabonomics and SystemsDock Fulltext Access 27 Pages 2018
Acute and subacute toxicity and chemical constituents of the hydroethanolic extract of Verbena litoralis Kunth Fulltext Access 27 Pages 2018
Analysis of heart rate variability-related indexes in the interictal period in patients with focal epilepsy Fulltext Access 28 Pages 2018
CXCR4 overexpression is correlated with poor prognosis in colorectal cancer Fulltext Access 28 Pages 2018
Metformin enhances cisplatin induced inhibition of cholangiocarcinoma cells via AMPK-mTOR pathway Fulltext Access 28 Pages 2018
SZSJ protects against insomnia by a decrease in ADMA level and an improvement in DDAH production in sleep-deprived rats Fulltext Access 28 Pages 2018
Crosstalk between transforming growth factor-β1 and endoplasmic reticulum stress regulates alpha-smooth muscle cell actin expression in podocytes Fulltext Access 28 Pages 2018
Bush mint (Hyptis suaveolens) and spreading hogweed (Boerhavia diffusa) medicinal plant extracts differentially affect activities of CYP1A2, CYP2D6 and CYP3A4 enzymes Fulltext Access 28 Pages 2018
Pudilan xiaoyan oral liquid alleviates LPS-induced respiratory injury through decreasing nitroxidative stress and blocking TLR4 activation along with NF-ÎB phosphorylation in mice Fulltext Access 28 Pages 2018
High hepatic exposure of furanocoumarins in Radix Angelica dahuricae is associated with transporter mediated active uptake Fulltext Access 28 Pages 2018
The effects of Cissampelos pareira extract on envenomation induced by Bothropsdiporus snake venom Fulltext Access 28 Pages 2018
An integrated evidence-based targeting strategy for determining combinatorial bioactive ingredients of a compound herbal medicine Qishen Yiqi dripping pills Fulltext Access 28 Pages 2018
Anti-inflammatory activity of Theobroma cacao L. stem bark ethanol extract and its fractions in experimental models Fulltext Access 28 Pages 2018
Traditional medicines used by Q'eqchi' Maya to treat diabetic symptoms and their antiglycation potential Fulltext Access 28 Pages 2018
Correlations between FEV1 and patient-reported outcomes: A pooled analysis of 23 clinical trials in patients with chronic obstructive pulmonary disease Fulltext Access 28 Pages 2018
Îlpha1B-adrenoceptor-mediated positive inotropic and positive chronotropic actions in the mouse atrium Fulltext Access 28 Pages 2018
Effect of efferocytosis of apoptotic mesenchymal stem cells (MSCs) on C57BL/6 peritoneal macrophages function Fulltext Access 28 Pages 2018
A novel selenonucleoside suppresses tumor growth by targeting Skp2 degradation in paclitaxel-resistant prostate cancer Fulltext Access 28 Pages 2018
Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target Fulltext Access 28 Pages 2018
Naoxintong restores collateral blood flow in a murine model of hindlimb ischemia through PPARδ-dependent mechanism Fulltext Access 28 Pages 2018
Activation of endothelial TrkB receptors induces relaxation of resistance arteries Fulltext Access 28 Pages 2018
Asymmetric dimethylarginine contributes to retinal neovascularization of diabetic retinopathy through EphrinB2 pathway Fulltext Access 28 Pages 2018
Toxicological assessment of PEGylated single-walled carbon nanotubes in early developing zebrafish Fulltext Access 28 Pages 2018
Course-, dose-, and stage-dependent toxic effects of prenatal dexamethasone exposure on long bone development in fetal mice Fulltext Access 28 Pages 2018
BET-inhibition by JQ1 alleviates streptozotocin-induced diabetic cardiomyopathy Fulltext Access 28 Pages 2018
Aerosol delivery during spontaneous breathing with different types of nebulizers- in vitro/ex vivo models evaluation Fulltext Access 28 Pages 2018
Prolonged-access to cocaine induces distinct Homer2 DNA methylation, hydroxymethylation, and transcriptional profiles in the dorsomedial prefrontal cortex of Male Sprague-Dawley rats Fulltext Access 28 Pages 2018
MDMA-assisted psychotherapy for PTSD: Are memory reconsolidation and fear extinction underlying mechanisms? Fulltext Access 28 Pages 2018
Notch1 knockdown disturbed neural oscillations in the hippocampus of C57BL mice Fulltext Access 28 Pages 2018
Pharmacological and transcriptional inhibition of the G9a histone methyltransferase suppresses proliferation and modulates redox homeostasis in human microvascular endothelial cells Fulltext Access 28 Pages 2018
Single-nucleotide polymorphisms in the genes of CES2, CDA and enzymatic activity of CDA for prediction of the efficacy of capecitabine-containing chemotherapy in patients with metastatic breast cancer Fulltext Access 28 Pages 2018
HIV infection and its effects on the development of autoimmune disorders Fulltext Access 28 Pages 2018
CHST3 and CHST13 polymorphisms as predictors of bosentan-induced liver toxicity in Japanese patients with pulmonary arterial hypertension Fulltext Access 28 Pages 2018
Oleuropein potentiates anti-tumor activity of cisplatin against HepG2 through affecting proNGF/NGF balance Fulltext Access 28 Pages 2018
SerpinB3 induces dipeptidyl-peptidase IV/CD26 expression and its metabolic effects in hepatocellular carcinoma Fulltext Access 28 Pages 2018
Fisetin inhibits IL-31 production in stimulated human mast cells: Possibilities of fisetin being exploited to treat histamine-independent pruritus Fulltext Access 28 Pages 2018
Dehydroepiandrosterone supplementation is not beneficial in the late postmenopausal period in diet-induced obese rats Fulltext Access 28 Pages 2018
A SNAP-25 cleaving chimera of botulinum neurotoxin /A and /E prevents TNF뱉induced elevation of the activities of native TRP channels on early postnatal rat dorsal root ganglion neurons Fulltext Access 28 Pages 2018
StaySafe: A self-administered android tablet application for helping individuals on probation make better decisions pertaining to health risk behaviors Fulltext Access 28 Pages 2018
Tatanan A from the Acorus calamus L. root inhibited dengue virus proliferation and infections Fulltext Access 28 Pages 2018
Bavachalcone from Cullen corylifolium induces apoptosis and autophagy in HepG2 cells Fulltext Access 28 Pages 2018
Chemical analysis of aqueous extracts of Origanum majorana and Foeniculum vulgare and their efficacy on Blastocystis spp. cysts Fulltext Access 28 Pages 2018
Determination of quality markers of Xuezhiling tablet for hyperlipidemia treatment Fulltext Access 28 Pages 2018
Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway Fulltext Access 28 Pages 2018
Endogenous glutamate within the prelimbic and infralimbic cortices regulates the incubation of cocaine-seeking in rats Fulltext Access 28 Pages 2018
Striatal GluN2B involved in motor skill learning and stimulus-response learning Fulltext Access 28 Pages 2018
Anti-aging properties of Curcuma heyneana Valeton & Zipj: A scientific approach to its use in Javanese tradition Fulltext Access 28 Pages 2018
Modulation of appetitive motivation by prefrontal cortical mu-opioid receptors is dependent upon local dopamine D1 receptor signaling Fulltext Access 28 Pages 2018
Chronic treatment with the phytocannabinoid Cannabidivarin (CBDV) rescues behavioural alterations and brain atrophy in a mouse model of Rett syndrome Fulltext Access 28 Pages 2018
Protective effects of IFN-γ on the kidney of type- 2 diabetic KKAy mice Fulltext Access 28 Pages 2018
Crystalline Polymorphism Emerging From a Milling-Induced Amorphous Form: The Case of Chlorhexidine Dihydrochloride Fulltext Access 28 Pages 2018
The combined therapeutic effects of 131iodine-labeled multifunctional copper sulfide-loaded microspheres in treating breast cancer Fulltext Access 28 Pages 2018
The emerging role of copper-64 radiopharmaceuticals as cancer theranostics Fulltext Access 28 Pages 2018
Reduced type III neuregulin 1 expression does not modulate the behavioural sensitivity of mice to acute Î9-tetrahydrocannabinol (D9-THC) Fulltext Access 28 Pages 2018
MicroRNA-143-3p inhibits growth and invasiveness of melanoma cells by targeting cyclooxygenase-2 and inversely correlates with malignant melanoma progression Fulltext Access 28 Pages 2018
Effects on skin of Stichopus japonicus viscera extracts detected with saponin including Holothurin A: Down-regulation of melanin synthesis and up-regulation of neocollagenesis mediated by ERK signaling pathway Fulltext Access 28 Pages 2018
A novel Danshensu/tetramethylpyrazine derivative induces vasorelaxation on rat aorta and exerts cardioprotection in dogs Fulltext Access 28 Pages 2018
Impact of mast cells in mucosal immunity of intestinal inflammation: Inhibitory effect of IL-37 Fulltext Access 28 Pages 2018
Biphasic effect of sumatriptan on PTZ-induced seizures in mice: Modulation by 5-HT1B/D receptors and NOS/NO pathway Fulltext Access 28 Pages 2018
Antipsoriatic effect of fatty acid enriched fraction of Vernonia anthelmintica Willd. fruits Fulltext Access 28 Pages 2018
Oral supplementation with melatonin reduces oxidative damage and concentrations of inducible nitric oxide synthase, VEGF and matrix metalloproteinase 9 in the retina of rats with streptozotocin/nicotinamide induced pre-diabetes Fulltext Access 28 Pages 2018
Chitosan (CMD)-mediated co-delivery of SN38 and Snail-specific siRNA as a useful anticancer approach against prostate cancer Fulltext Access 28 Pages 2018
The antidepressant effects of É-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway Fulltext Access 28 Pages 2018
Sirt1 activation prevents anti-Thy 1.1 mesangial proliferative glomerulonephritis in the rat through the Nrf2/ARE pathway Fulltext Access 28 Pages 2018
G protein-coupled receptor 39 plays an anti-inflammatory role by enhancing IL-10 production from macrophages under inflammatory conditions Fulltext Access 28 Pages 2018
Pharmacological evaluation of new bioavailable small molecules targeting Eph/ephrin interaction Fulltext Access 28 Pages 2018
Integration of biological/pathophysiological contexts to help clarify genotype-phenotype mismatches in monogenetic diseases. Childhood epilepsies associated with SCN2A as a case study Fulltext Access 28 Pages 2018
Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and endogenous non-chemokine agonists Fulltext Access 28 Pages 2018
Artesunate-derived monomeric, dimeric and trimeric experimental drugs - Their unique mechanistic basis and pronounced antiherpesviral activity Fulltext Access 28 Pages 2018
Combination of CYP2C19 genotype with non-genetic factors evoking phenoconversion improves phenotype prediction Fulltext Access 29 Pages 2018
Endocannabinoid-mediated modulation of Gq protein-coupled receptor mediates vascular hyporeactivity to nor-adrenaline during polymicrobial sepsis Fulltext Access 29 Pages 2018
Helioscopianoids A-Q, bioactive jatrophane diterpenoid esters from Euphorbia helioscopia Fulltext Access 29 Pages 2018
Curcumin inhibits cardiac hypertrophy and improves cardiovascular function via enhanced Na+/Ca2+ exchanger expression after transverse abdominal aortic constriction in rats Fulltext Access 29 Pages 2018
Pregabalin and lacosamide ameliorate paclitaxel-induced peripheral neuropathy via inhibition of JAK/STAT signaling pathway and Notch-1 receptor Fulltext Access 29 Pages 2018
The role of nitric oxide-cGMP pathway in selegiline antidepressant-like effect in the mice forced swim test Fulltext Access 29 Pages 2018
CDC42EP4, a perisynaptic scaffold protein in Bergmann glia, is required for glutamatergic tripartite synapse configuration Fulltext Access 29 Pages 2018
Neuropathic pain inhibitor, RAP-103, is a potent inhibitor of microglial CCL1/CCR8 Fulltext Access 29 Pages 2018
Nanoparticles with high payloads of pipemidic acid, a poorly soluble crystalline drug: drug-initiated polymerization and self-assembly approach Fulltext Access 29 Pages 2018
Characterization of Aptamer BC 007 Substance and Product Using Circular Dichroism and Nuclear Magnetic Resonance Spectroscopy Fulltext Access 29 Pages 2018
Synthesis of a Glibenclamide Cocrystal: Full Spectroscopic and Thermal Characterization Fulltext Access 29 Pages 2018
Beyond Q1/Q2: The Impact of Manufacturing Conditions and Test Methods on Drug Release From PLGA-Based Microparticle Depot Formulations Fulltext Access 29 Pages 2018
Pannexin-1 channel dysfunction in the medial prefrontal cortex mediates depressive-like behaviors induced by chronic social defeat stress and administration of mefloquine in mice Fulltext Access 29 Pages 2018
Disease-modifying benefit of Fyn blockade persists after washout in mouse Alzheimer's model Fulltext Access 29 Pages 2018
Melanin-Concentrating Hormone acts through hypothalamic kappa opioid system and p70S6K to stimulate acute food intake Fulltext Access 29 Pages 2018
Role of Wnt4/β-catenin, Ang II/TGFβ, ACE2, NF-κB, and IL-18 in attenuating renal ischemia/reperfusion-induced injury in rats treated with Vit D and pioglitazone Fulltext Access 29 Pages 2018