Adenovirus-mediated overexpression of sST2 attenuates cardiac injury in the rat with severe acute pancreatitis Fulltext Access 30 Pages 2018
Expression of cytochrome P450 epoxygenases and soluble epoxide hydrolase is regulated by hypolipidemic drugs in dose-dependent manner Fulltext Access 30 Pages 2018
Eicosapentaenoic and docosahexaenoic acids have different effects on peripheral phospholipase A2 gene expressions in acute depressed patients Fulltext Access 30 Pages 2018
Association of PIK3CG gene polymorphisms with attention-deficit/hyperactivity disorder: A case-control study Fulltext Access 30 Pages 2018
The effects of serotonin modulation on medial prefrontal connectivity strength and stability: A pharmacological fMRI study with citalopram Fulltext Access 30 Pages 2018
Translocator protein (18Â kDa TSPO) binding, a marker of microglia, is reduced in major depression during cognitive-behavioral therapy Fulltext Access 30 Pages 2018
Matrine inhibiting pancreatic cells epithelial-mesenchymal transition and invasion through ROS/NF-κB/MMPs pathway Fulltext Access 30 Pages 2018
Total flavonoid extract from Dracoephalum moldavica L. attenuates β-amyloid-induced toxicity through anti-amyloidogenesic and neurotrophic pathways Fulltext Access 30 Pages 2018
Experimental periodontitis in rats potentiates inflammation at a distant site: Role of B1 kinin receptor Fulltext Access 30 Pages 2018
Monosodium glutamate induced nociception and oxidative stress dependent on time of administration, age of rats and susceptibility of spinal cord and brain regions Fulltext Access 30 Pages 2018
LQFM030 reduced Ehrlich ascites tumor cell proliferation and VEGF levels Fulltext Access 30 Pages 2018
The mechanistic effects of the dioxonaphthoimidazolium analog YM155 in renal cell carcinoma cell cycling and apoptosis Fulltext Access 30 Pages 2018
Slit2-Robo2 signaling modulates the fibrogenic activity and migration of hepatic stellate cells Fulltext Access 30 Pages 2018
Celastrol attenuates incision-induced inflammation and pain associated with inhibition of the NF-κB signalling pathway via SARM Fulltext Access 30 Pages 2018
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway Fulltext Access 30 Pages 2018
Caffeic acid phenethyl ester promotes wound healing of mice pressure ulcers affecting NF-κB, NOS2 and NRF2 expression Fulltext Access 30 Pages 2018
Neuralized1a regulates asymmetric division in mouse Lewis lung carcinoma cells Fulltext Access 30 Pages 2018
Wall shear stress promotes intimal hyperplasia through the paracrine H2O2-mediated NOX-AKT-SVV axis Fulltext Access 30 Pages 2018
DUSP1 alleviates cerebral ischaemia reperfusion injury via inactivating JNK-Mff pathways and repressing mitochondrial fission Fulltext Access 30 Pages 2018
ERK1/2-mediated autophagy is essential for cell survival under Ochratoxin A exposure in IPEC-J2 cells Fulltext Access 30 Pages 2018
Cunaniol-elicited seizures: Behavior characterization and electroencephalographic analyses Fulltext Access 30 Pages 2018
Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3 Fulltext Access 30 Pages 2018
Triptolide enhances chemotherapeutic efficacy of antitumor drugs in non-small-cell lung cancer cells by inhibiting Nrf2-ARE activity Fulltext Access 30 Pages 2018
Pharmacokinetics and safety of a single dose of the novel LAMA/LABA fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate metered dose inhaler, formulated using co-suspension delivery technology, in Japanese healthy subjects Fulltext Access 30 Pages 2018
Differential regulation of cytokine and chemokine expression by MK2 and MK3 in airway smooth muscle cells Fulltext Access 30 Pages 2018
Dihydromyricetin from ampelopsis grossedentata protects against vascular neointimal formation via induction of TR3 Fulltext Access 30 Pages 2018
Bevacizumab with dose-dense paclitaxel/carboplatin as first-line chemotherapy for advanced ovarian cancer Fulltext Access 30 Pages 2018
Huntingtin protein: A new option for fixing the Huntington's disease countdown clock Fulltext Access 30 Pages 2018
A new platinum-based prodrug candidate: Its anticancer effects in B50 neuroblastoma rat cells Fulltext Access 30 Pages 2018
L-tryptophan administration and increase in cerebral serotonin levels: Systematic review Fulltext Access 30 Pages 2018
MicroRNA-494 inhibition alleviates acute lung injury through Nrf2 signaling pathway via NQO1 in sepsis-associated acute respiratory distress syndrome Fulltext Access 30 Pages 2018
Prostaglandin D2 evokes potent uterine contraction via the F prostanoid receptor in postpartum rats Fulltext Access 30 Pages 2018
Pre-clinical pharmacodynamic study of a novel oral factor Xa inhibitor zifaxaban Fulltext Access 30 Pages 2018
HPLC-DAD fingerprinting analysis, antioxidant activities of Tithonia diversifolia (Hemsl.) A. Gray leaves and its inhibition of key enzymes linked to Alzheimer's disease Fulltext Access 30 Pages 2018
NiO nanoparticles induce cytotoxicity mediated through ROS generation and impairing the antioxidant defense in the human lung epithelial cells (A549): Preventive effect of Pistacia lentiscus essential oil Fulltext Access 30 Pages 2018
Analysis of 3â²,5â²-dichloro-2,3,4-trihydroxy-2-methylbutylanilide (DTMBA) as a new potential biomarker of exposure to vinclozolin in urine Fulltext Access 30 Pages 2018
Dexmedetomidine attenuates renal fibrosis via α2-adrenergic receptor-dependent inhibition of cellular senescence after renal ischemia/reperfusion Fulltext Access 30 Pages 2018
Suppression of lung inflammation by the methanol extract of Spilanthes acmella Murray is related to differential regulation of NF-κB and Nrf2 Fulltext Access 30 Pages 2018
Mucuna pruriens (L.) DC chemo sensitize human breast cancer cells via downregulation of prolactin-mediated JAK2/STAT5A signaling Fulltext Access 30 Pages 2018
Secretoneurin suppresses cardiac hypertrophy through suppression of oxidant stress Fulltext Access 30 Pages 2018
Protective effect of Sesbania grandiflora on acetic acid induced ulcerative colitis in mice by inhibition of TNF-α and IL-6 Fulltext Access 30 Pages 2018
Chemical characterization, pharmacological effects, and toxicity of an ethanol extract of Celtis pallida Torr. (Cannabaceae) aerial parts Fulltext Access 30 Pages 2018
Himatanthus drasticus (Apocynaceae) latex reduces oxidative stress and modulates CD4+, CD8+, FoxP3+ and HSP-60+ expressions in Sarcoma 180-bearing mice Fulltext Access 30 Pages 2018
Relaxant effect of Lippia origanoides essential oil in guinea-pig trachea smooth muscle involves potassium channels and soluble guanylyl cyclase Fulltext Access 30 Pages 2018
Glucagon-like Peptide-1 (GLP-1) and neurotransmitters signaling in epilepsy: An insight review Fulltext Access 30 Pages 2018
Berberine protects acute liver failure in mice through inhibiting inflammation and mitochondria-dependent apoptosis Fulltext Access 30 Pages 2018
Suppressive effects of Vochysia divergens aqueous leaf extract and its 5-methoxyflavone on murine macrophages and lymphocytes Fulltext Access 30 Pages 2018
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved Fulltext Access 30 Pages 2018
Ethnobotany of dioecious species: Traditional knowledge on dioecious plants in India Fulltext Access 30 Pages 2018
Inhibition of Notch1/Hes1 signaling pathway improves radiosensitivity of colorectal cancer cells Fulltext Access 30 Pages 2018
Total saponins of Albiziae Cortex show anti-hepatoma carcinoma effects by inducing S phase arrest and mitochondrial apoptosis pathway activation Fulltext Access 30 Pages 2018
Toxicological evaluation and anti-inflammatory potential of an ethanolic extract from Bromelia balansae (Bromeliaceae) fruit Fulltext Access 30 Pages 2018
Four new diterpenes from the mangrove Ceriops tagal and structure revision of four dolabranes with a 4,18-epoxy group Fulltext Access 30 Pages 2018
COX inhibitors and bone: A safer impact on osteoblasts by NO-releasing NSAIDs Fulltext Access 30 Pages 2018
An improved CPRG colorimetric ligand-receptor signal transduction assay based on beta-galactosidase activity in mammalian BWZ-reporter cells Fulltext Access 30 Pages 2018
Optimizing the dosing schedule of l-asparaginase improves its anti-tumor activity in breast tumor-bearing mice Fulltext Access 30 Pages 2018
Protective effect of Terminalia chebula against seizures, seizure-induced cognitive impairment and oxidative stress in experimental models of seizures in rats Fulltext Access 30 Pages 2018
Lysosomotropic cationic amphiphilic drugs inhibit adipocyte differentiation in 3T3-L1K cells via accumulation in cells and phospholipid membranes, and inhibition of autophagy Fulltext Access 30 Pages 2018
Enhanced incentive motivation in obesity-prone rats is mediated by NAc core CP-AMPARs Fulltext Access 30 Pages 2018
Effects of a hydroethanolic extract of Boophone disticha bulb on anxiety-related behaviour in naive BALB/c mice Fulltext Access 30 Pages 2018
Inhaled Lavandula angustifolia essential oil inhibits consolidation of contextual- but not tone-fear conditioning in rats Fulltext Access 30 Pages 2018
Eucalyptus robusta leaves methanolic extract suppresses inflammatory mediators by specifically targeting TLR4/TLR9, MPO, COX2, iNOS and inflammatory cytokines in experimentally-induced endometritis in rats Fulltext Access 30 Pages 2018
Dauricine combined with clindamycin inhibits severe pneumonia co-infected by influenza virus H5N1 and Streptococcus pneumoniae in vitro and in vivo through NF-κB signaling pathway Fulltext Access 30 Pages 2018
Removal of hERG potassium channel affinity through introduction of an oxygen atom: Molecular insights from structure-activity relationships of strychnine and its analogs Fulltext Access 31 Pages 2018
Safety and pharmacokinetics of budesonide/glycopyrronium/formoterol fumarate dihydrate metered dose inhaler (BGF MDI) in healthy adult subjects of Japanese descent Fulltext Access 31 Pages 2018
Inducible SHP-2 activation confers resistance to imatinib in drug-tolerant chronic myeloid leukemia cells Fulltext Access 31 Pages 2018
Chrysophanol selectively represses breast cancer cell growth by inducing reactive oxygen species production and endoplasmic reticulum stress via AKT and mitogen-activated protein kinase signal pathways Fulltext Access 31 Pages 2018
7-Fluoro-1,3-diphenylisoquinoline reverses motor and non-motor symptoms induced by MPTP in mice: Role of striatal neuroinflammation Fulltext Access 31 Pages 2018
Anti-inflammatory activity of the decoction of Forsythia suspensa (Thunb.) Vahl is related to Nrf2 and A20 Fulltext Access 31 Pages 2018
Trigonelline inhibits caspase 3 to protect β cells apoptosis in streptozotocin-induced type 1 diabetic mice Fulltext Access 31 Pages 2018
Moderate-intensity exercise and renin angiotensin system blockade improve the renovascular hypertension (2K1C)-induced gastric dysmotility in rats Fulltext Access 31 Pages 2018
Characterization of a novel selective factor Xa inhibitor, DJT06001, which reduces thrombus formation with low risk of bleeding Fulltext Access 31 Pages 2018
Inhibition of activated factor X by rivaroxaban attenuates neointima formation after wire-mediated vascular injury Fulltext Access 31 Pages 2018
Inhibition of Rho kinase by GSK 269962 reverses both corticosterone-induced detrusor overactivity and depression-like behaviour in rats Fulltext Access 31 Pages 2018
Combined iron chelator and T-type calcium channel blocker exerts greater efficacy on cardioprotection than monotherapy in iron-overload thalassemic mice Fulltext Access 31 Pages 2018
Root bark of Discaria americana attenuates pain: A pharmacological evidence of interaction with opioidergic system and TRP/ASIC channels Fulltext Access 31 Pages 2018
(E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol attenuates PMA-induced inflammatory responses in human monocytic cells through PKCδ/JNK/AP-1 pathways Fulltext Access 31 Pages 2018
Ginsenoside Rg1 protects rat bone marrow mesenchymal stem cells against ischemia induced apoptosis through miR-494-3p and ROCK-1 Fulltext Access 31 Pages 2018
Proprotein Convertase Subtilisin-Kexin type-9 (PCSK9) and triglyceride-rich lipoprotein metabolism: Facts and gaps Fulltext Access 31 Pages 2018
Exogenous hydrogen sulfide ameliorates high glucose-induced myocardial injury & inflammation via the CIRP-MAPK signaling pathway in H9c2 cardiac cells Fulltext Access 31 Pages 2018
Induction of brain Nrf2-HO-1 pathway and antinociception after different physical training paradigms in mice Fulltext Access 31 Pages 2018
Atorvastatin, losartan and captopril may upregulate IL-22 in hypertension and coronary artery disease; the role of gene polymorphism Fulltext Access 31 Pages 2018
The diagnostic value of long non-coding RNA MIR31HG and its role in esophageal squamous cell carcinoma Fulltext Access 31 Pages 2018
Two tandem repeats of mHSP70407-426 enhance therapeutic antitumor effects of a recombined vascular endothelial growth factor (VEGF) protein vaccine Fulltext Access 31 Pages 2018
Therapeutic mild hypothermia improves early outcomes in rats subjected to severe sepsis Fulltext Access 31 Pages 2018
Liraglutide regulates the viability of pancreatic α-cells and pancreatic β-cells through cAMP-PKA signal pathway Fulltext Access 31 Pages 2018
Ethanol-induced cardiomyocyte toxicity implicit autophagy and NFkB transcription factor Fulltext Access 31 Pages 2018
Neurotoxic effect of oxaliplatin: Comparison with its oxalate-free analogue cis-[PtII(1R,2R-DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)] (LLC-1402) in mice Fulltext Access 31 Pages 2018
CAR-T cells and combination therapies: What's next in the immunotherapy revolution? Fulltext Access 31 Pages 2018
A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer Fulltext Access 31 Pages 2018
The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target Fulltext Access 31 Pages 2018
The theta burst transcranial magnetic stimulation over the right PFC affects electroencephalogram oscillation during emotional processing Fulltext Access 31 Pages 2018
Evaluating psychiatric symptoms in Parkinson's Disease by a clinimetric analysis of the Hopkins Symptom Checklist (SCL-90-R) Fulltext Access 31 Pages 2018
CRISPR-engineered genome editing for the next generation neurological disease modeling Fulltext Access 31 Pages 2018
Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways Fulltext Access 31 Pages 2018
Monoclonal antibody targeting of fibroblast growth factor receptor 1c causes cardiac valvulopathy in rats Fulltext Access 31 Pages 2018
Neuroprotective effect of linagliptin against cuprizone-induced demyelination and behavioural dysfunction in mice: A pivotal role of AMPK/SIRT1 and JAK2/STAT3/NF-κB signalling pathway modulation Fulltext Access 31 Pages 2018