Tenuigenin inhibits LPS-induced inflammatory responses in microglia via activating the Nrf2-mediated HO-1 signaling pathway Fulltext Access 7 Pages 2017
Troxerutin exerts neuroprotection in 6-hydroxydopamine lesion rat model of Parkinson's disease: Possible involvement of PI3K/ERβ signaling Fulltext Access 7 Pages 2017
Eicosapentaenoic acid monoglyceride resolves inflammation in an ex vivo model of human peripheral blood mononuclear cell Fulltext Access 7 Pages 2017
Tetrandrine potentiates the glucocorticoid pharmacodynamics via inhibiting P-glycoprotein and mitogen-activated protein kinase in mitogen-activated human peripheral blood mononuclear cells Fulltext Access 7 Pages 2017
MAGL inhibition modulates gastric secretion and motility following NSAID exposure in mice Fulltext Access 7 Pages 2017
Diammonium glycyrrhizinate alleviates hepatopulmonary syndrome via restoring superoxide dismutase 3 activity in rats Fulltext Access 7 Pages 2017
Endothelium-dependent vasorelaxant effect of procyanidin B2 on human internal mammary artery Fulltext Access 7 Pages 2017
T3 peptide, an active fragment of tumstatin, inhibits H2O2-induced apoptosis in H9c2 cardiomyoblasts Fulltext Access 7 Pages 2017
Curcumin and its cyclohexanone analogue inhibited human Equilibrative nucleoside transporter 1 (ENT1) in pancreatic cancer cells Fulltext Access 7 Pages 2017
Anhydroicaritin, a SREBPs inhibitor, inhibits RANKL-induced osteoclastic differentiation and improves diabetic osteoporosis in STZ-induced mice Fulltext Access 7 Pages 2017
ATP-sensitive K+ channels maintain resting membrane potential in interstitial cells of Cajal from the mouse colon Fulltext Access 7 Pages 2017
Omecamtiv mecarbil activates ryanodine receptors from canine cardiac but not skeletal muscle Fulltext Access 7 Pages 2017
Serotonin-2A homodimers are needed for signalling via both phospholipase A2 and phospholipase C in transfected CHO cells Fulltext Access 7 Pages 2017
Mangiferin protects against âintestinal ischemia/reperfusion-induced âliver injury: â¬â¬Involvement of PPAR-âγ, GSK-3β and Wnt/β-catenin pathwayâ¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬â¬ Fulltext Access 7 Pages 2017
β2-Microglobulin elicits itch-related responses in mice through the direct activation of primary afferent neurons expressing transient receptor potential vanilloid 1 Fulltext Access 7 Pages 2017
Methyl (E)-(3-(3,4-dihydroxyphenyl)acryloyl)tryptophanate can suppress MCP-1 expression by inhibiting p38 MAP kinase and NF-κB in LPS-stimulated differentiated THP-1 cells Fulltext Access 7 Pages 2017
Chronic fluoxetine treatment enhances sympathetic activities associated with abnormality of baroreflex function in conscious normal rats Fulltext Access 7 Pages 2017
Pharmacological characterization of a novel potent, selective, and orally active phosphodiesterase 2A inhibitor, PDM-631 Fulltext Access 7 Pages 2017
Medical ozone promotes Nrf2 phosphorylation reducing oxidative stress and pro-inflammatory cytokines in multiple sclerosis patients Fulltext Access 7 Pages 2017
TAK1 as the mediator in the protective effect of propofol on renal interstitial fibrosis induced by ischemia/reperfusion injury Fulltext Access 7 Pages 2017
Roflumilast treatment inhibits lung carcinogenesis in benzo(a)pyrene-induced murine lung cancer model Fulltext Access 7 Pages 2017
Pharmacological analysis of the inhibition produced by moxonidine and agmatine on the vasodepressor sensory CGRPergic outflow in pithed rats Fulltext Access 7 Pages 2017
Opioid receptor activation is involved in neuroprotection induced by TRPV1 channel activation against excitotoxicity in the rat retina Fulltext Access 7 Pages 2017
Piperlongumine inhibits TGF-β-induced epithelial-to-mesenchymal transition by modulating the expression of E-cadherin, Snail1, and Twist1 Fulltext Access 7 Pages 2017
GZ-793A inhibits the neurochemical effects of methamphetamine via a selective interaction with the vesicular monoamine transporter-2 Fulltext Access 7 Pages 2017
Presence of the methylenetetrahydrofolate reductase gene polymorphism MTHFR C677T in molar tissue but not maternal blood predicts failure of methotrexate treatment for low-risk gestational trophoblastic neoplasia Fulltext Access 7 Pages 2017
Demonstration of rebound phenomenon following abrupt withdrawal of the JAK1 inhibitor oclacitinib Fulltext Access 7 Pages 2017
CysLT2 receptor activation is involved in LTC4-induced lung air-trapping in guinea pigs Fulltext Access 7 Pages 2017
The endogenous lipid N-arachidonoyl glycine is hypotensive and nitric oxide-cGMP-dependent vasorelaxant Fulltext Access 7 Pages 2017
TLR4/NF-κB/Ceramide signaling contributes to Ox-LDL-induced calcification of human vascular smooth muscle cells Fulltext Access 7 Pages 2017
AS2553627, a novel JAK inhibitor, prevents chronic rejection in rat cardiac allografts Fulltext Access 7 Pages 2017
Human native Cav1 channels in chromaffin cells: contribution to exocytosis and firing of spontaneous action potentials Fulltext Access 7 Pages 2017
The protective effect of curcumin in Olfactory Ensheathing Cells exposed to hypoxia Fulltext Access 7 Pages 2017
Evaluating the role of astrocytes on β-estradiol effect on seizures of Pilocarpine epileptic model Fulltext Access 7 Pages 2017
Small molecule antidepressant amitriptyline protects hypoxia/reoxygenation-induced cardiomyocyte apoptosis through TrkA signaling pathway Fulltext Access 7 Pages 2017
Inhibitory effects of antihistamines, diphenhydramine and chlorpheniramine, on proton currents in BV2 microglial cells Fulltext Access 7 Pages 2017
The effects of sildenafil citrate on uterine angiogenic status and serum inflammatory markers in an L-NAME rat model of pre-eclampsia Fulltext Access 7 Pages 2017
Prostaglandin D2 is the major cyclooxygenase-1-derived product in prepartum mouse uteri where it mediates an enhanced in vitro myometrial contraction Fulltext Access 7 Pages 2017
Implication of protein kinase C of the left intermediate medial mesopallium in memory impairments induced by early prenatal morphine exposure in one-day old chicks Fulltext Access 7 Pages 2017
ADX71943 and ADX71441, novel positive allosteric modulators of the GABAB receptor with distinct central/peripheral profiles, show efficacy in the monosodium iodoacetate model of chronic osteoarthritis pain in the rat Fulltext Access 7 Pages 2017
Inhibition of the potassium channel KCa3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury Fulltext Access 7 Pages 2017
Apomorphine prevents LPS-induced IL-23 p19 mRNA expression via inhibition of JNK and ATF4 in HAPI cells Fulltext Access 7 Pages 2017
Acquisition and expression of fat-conditioned flavor preferences are differentially affected by NMDA receptor antagonism in BALB/c and SWR mice Fulltext Access 7 Pages 2017
Ameliorative effects of sildenafil and/or febuxostat on doxorubicin-induced nephrotoxicity in rats Fulltext Access 7 Pages 2017
Targeted inhibition of HDAC8 increases the doxorubicin sensitivity of neuroblastoma cells via up regulation of miR-137 Fulltext Access 7 Pages 2017
Anti-human CD14 monoclonal antibody improves survival following sepsis induced by endotoxin, but not following polymicrobial infection Fulltext Access 7 Pages 2017
Mizagliflozin, a novel selective SGLT1 inhibitor, exhibits potential in the amelioration of chronic constipation Fulltext Access 7 Pages 2017
Modulation of cerebral RAGE expression following nitric oxide synthase inhibition in rats subjected to focal cerebral ischemia Fulltext Access 7 Pages 2017
Chemical constituents and pharmacological actions of carob pods and leaves (Ceratonia siliqua L.) on the gastrointestinal tract: A review Fulltext Access 7 Pages 2017
An increased expression of long non-coding RNA PANDAR promotes cell proliferation and inhibits cell apoptosis in pancreatic ductal adenocarcinoma Fulltext Access 7 Pages 2017
Exceptionally high UBE2C expression is a unique phenomenon in basal-like type breast cancer and is regulated by BRCA1 Fulltext Access 7 Pages 2017
SPOCK1 promotes the growth of Osteosarcoma cells through mTOR-S6K signaling pathway Fulltext Access 7 Pages 2017
PEG modification of Amorfrutin B from Amorpha fructicosa increases gastric absorption, circulation half-life and glucose uptake by T3T-L1 adipocytes Fulltext Access 7 Pages 2017
Upregulation of miR-3607 promotes lung adenocarcinoma proliferation by suppressing APC expression Fulltext Access 7 Pages 2017
Ginkgo biloba L. leaf extract offers multiple mechanisms in bridling N-methylnitrosourea - mediated experimental colorectal cancer Fulltext Access 7 Pages 2017
Decreased expression of cytochrome p450 1B1 in non-small cell lung cancer Fulltext Access 7 Pages 2017
Paraquat exposure-induced Parkinson's disease-like symptoms and oxidative stress in Drosophila melanogaster: Neuroprotective effect of Bougainvillea glabra Choisy Fulltext Access 7 Pages 2017
VDAC1 deacetylation is involved in the protective effects of resveratrol against mitochondria-mediated apoptosis in cardiomyocytes subjected to anoxia/reoxygenation injury Fulltext Access 7 Pages 2017
Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo Fulltext Access 7 Pages 2017
Carapax Trionycis extracts inhibit fibrogenesis of activated hepatic stellate cells via TGF-β1/Smad and NFκB signaling Fulltext Access 7 Pages 2017
Baicalein: A review of its anti-cancer effects and mechanisms in Hepatocellular Carcinoma Fulltext Access 7 Pages 2017
Ginsenoside Rg3 enhances the anti-proliferative activity of erlotinib in pancreatic cancer cell lines by downregulation of EGFR/PI3K/Akt signaling pathway Fulltext Access 7 Pages 2017
Knockdown of Diaph1 expression inhibits migration and decreases the expression of MMP2 and MMP9 in human glioma cells Fulltext Access 7 Pages 2017
Protective effect of α-lipoic acid against spleen toxicity of dimethylnitrosamine in male mice: Antioxidant and ultrastructure approaches Fulltext Access 7 Pages 2017
Local anaesthetic pain relief therapy: In vitro and in vivo evaluation of a nanotechnological formulation co-loaded with ropivacaine and dexamethasone Fulltext Access 7 Pages 2017
Artesunate attenuates ACLT-induced osteoarthritis by suppressing osteoclastogenesis and aberrant angiogenesis Fulltext Access 7 Pages 2017
Antiviral activity of a polysaccharide from Laminaria japonica against enterovirus 71 Fulltext Access 7 Pages 2017
Tetrahydroxy stilbene glycoside (TSG) antagonizes Aβ-induced hippocampal neuron injury by suppressing mitochondrial dysfunction via Nrf2-dependent HO-1 pathway Fulltext Access 7 Pages 2017
Simvastatin exerts antifibrotic effect and potentiates the antischistosomal effects of praziquantel in a murine model: Role of IL10 Fulltext Access 7 Pages 2017
MiR-140-5p inhibits synovial fibroblasts proliferation and inflammatory cytokines secretion through targeting TLR4 Fulltext Access 7 Pages 2017
miR-205 regulation of ICT1 has an oncogenic potential via promoting the migration and invasion of gastric cancer cells Fulltext Access 7 Pages 2017
Community-dwelling older people's attitudes towards deprescribing in Canada Fulltext Access 7 Pages 2017
The anti-inflammatory and antinociceptive activity of albumins from Crotalaria retusa seeds Fulltext Access 7 Pages 2017
Aripiprazole prevents renal ischemia/reperfusion injury in rats, probably through nitric oxide involvement Fulltext Access 7 Pages 2017
A preclinical study on the combined effects of repeated eltoprazine and preladenant treatment for alleviating L-DOPA-induced dyskinesia in Parkinson's disease Fulltext Access 7 Pages 2017
Salvianolic acid B inhibits intermittent high glucose-induced INS-1 cell apoptosis through regulation of Bcl-2 proteins and mitochondrial membrane potential Fulltext Access 7 Pages 2017
Effects of SPAK on vascular reactivity and nitric oxide production in endotoxemic mice Fulltext Access 7 Pages 2017
Carvedilol abrogates hypoxia-induced oxidative stress and neuroinflammation in microglial BV2 cells Fulltext Access 7 Pages 2017
Tranexamic acid impairs hippocampal synaptic transmission mediated by gamma aminobutyric acid receptor type A Fulltext Access 7 Pages 2017
Ferulic acid relaxed rat aortic, small mesenteric and coronary arteries by blocking voltage-gated calcium channel and calcium desensitization via dephosphorylation of ERK1/2 and MYPT1 Fulltext Access 7 Pages 2017
In vitro and in vivo pharmacological characterization of ASP8477: A novel highly selective fatty acid amide hydrolase inhibitor Fulltext Access 7 Pages 2017
Oligomeric proanthocyanidin derived from grape seeds inhibited NF-κB signaling in activated HSC: Involvement of JNK/ERK MAPK and PI3K/Akt pathways Fulltext Access 7 Pages 2017
Overexpression of low-density lipoprotein receptors stimulated by vascular endothelial growth factor in fibroblasts from pterygium Fulltext Access 7 Pages 2017
Protective effects of tropisetron on cerulein-induced acute pancreatitis in mice Fulltext Access 7 Pages 2017
MiR-30c-5p suppresses migration, invasion and epithelial to mesenchymal transition of gastric cancer via targeting MTA1 Fulltext Access 7 Pages 2017
Pectolinarigenin from the leaves of Clerodendrum volubile shows potent immunomodulatory activity by inhibiting T â cell proliferation and modulating respiratory oxidative burst in phagocytes Fulltext Access 7 Pages 2017
Carnitine/organic cation transporter 2 (OCTN2) contributes to rat epididymal epithelial cell growth and proliferation Fulltext Access 7 Pages 2017
Low expression of long noncoding RNA CASC2 indicates a poor prognosis and promotes tumorigenesis in thyroid carcinoma Fulltext Access 7 Pages 2017
Cardiaprotective effect of crocetin by attenuating apoptosis in isoproterenol induced myocardial infarction rat model Fulltext Access 7 Pages 2017
Tanshinone I alleviates insulin resistance in type 2 diabetes mellitus rats through IRS-1 pathway Fulltext Access 7 Pages 2017
Terminalia bellirica (Gaertn.) Roxb. fruit mitigates CCl4 induced oxidative stress and hepatotoxicity in rats Fulltext Access 7 Pages 2017
Effect of microRNA-129-5p targeting HMGB1-RAGE signaling pathway on revascularization in a collagenase-induced intracerebral hemorrhage rat model Fulltext Access 7 Pages 2017
Young leaves of reed (Phragmites communis) suppress melanogenesis and oxidative stress in B16F10 melanoma cells Fulltext Access 7 Pages 2017
Saponins extracted from Dioscorea collettii rhizomes regulate the expression of urate transporters in chronic hyperuricemia rats Fulltext Access 7 Pages 2017
Antiobesity, antioxidant and hepatoprotective effects of Diallyl trisulphide (DATS) alone or in combination with Orlistat on HFD induced obese rats Fulltext Access 7 Pages 2017
Overexpression of FADD and Caspase-8 inhibits proliferation and promotes apoptosis of human glioblastoma cells Fulltext Access 7 Pages 2017