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Pharmacology Research Articles

Astragaloside IV from Astragalus membranaceus ameliorates renal interstitial fibrosis by inhibiting inflammation via TLR4/NF-кB in vivo and in vitro
Fulltext Access 7 Pages 2017
The ADAPT online education program: A tool for practicing pharmacists delivering patient-centered care
Fulltext Access 7 Pages 2017
MicroRNA-135a is up-regulated and aggravates myocardial depression in sepsis via regulating p38 MAPK/NF-κB pathway
Fulltext Access 7 Pages 2017
Protective effect of zerumbone reduces lipopolysaccharide-induced acute lung injury via antioxidative enzymes and Nrf2/HO-1 pathway
Fulltext Access 7 Pages 2017
MicroRNA-93 alleviates neuropathic pain through targeting signal transducer and activator of transcription 3
Fulltext Access 7 Pages 2017
Curcumin inhibiting Th17 cell differentiation by regulating the metabotropic glutamate receptor-4 expression on dendritic cells
Fulltext Access 7 Pages 2017
Salvianolic acid B inhibits IL-1β-induced inflammatory cytokine production in human osteoarthritis chondrocytes and has a protective effect in a mouse osteoarthritis model
Fulltext Access 7 Pages 2017
Regulation of T helper cell differentiation by E3 ubiquitin ligases and deubiquitinating enzymes
Fulltext Access 7 Pages 2017
Inosine Acedoben Dimepranol promotes an early and sustained increase in the natural killer cell component of circulating lymphocytes: A clinical trial supporting anti-viral indications
Fulltext Access 7 Pages 2017
Identification of a hemolin protein from Actias selene mediates immune response to pathogens
Fulltext Access 7 Pages 2017
Compact bone-derived mesenchymal stem cells attenuate nonalcoholic steatohepatitis in a mouse model by modulation of CD4 cells differentiation
Fulltext Access 7 Pages 2017
Study on the physicochemical properties and anti-inflammatory effects of paeonol in rats with TNBS-induced ulcerative colitis
Fulltext Access 7 Pages 2017
Therapeutic activity of the histone deacetylase inhibitor SB939 on renal fibrosis
Fulltext Access 7 Pages 2017
A nationwide pharmacy chain responds to the opioid epidemic
Fulltext Access 7 Pages 2017
Changes in regulatory T cells in patients with ovarian cancer undergoing surgery: Preliminary results
Fulltext Access 7 Pages 2017
Chemical and biological properties of a supramolecular complex of tuftsin and cucurbit[7]uril
Fulltext Access 7 Pages 2017
Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK
Fulltext Access 7 Pages 2017
IFNγ enhances cytotoxic efficiency of the cytotoxic T lymphocytes against human glioma cells
Fulltext Access 7 Pages 2017
Long non-coding RNA PVT1 promote LPS-induced septic acute kidney injury by regulating TNFα and JNK/NF-κB pathways in HK-2 cells
Fulltext Access 7 Pages 2017
Tim3/Gal9 interactions between T cells and monocytes result in an immunosuppressive feedback loop that inhibits Th1 responses in osteosarcoma patients
Fulltext Access 7 Pages 2017
LAT alleviates Th2/Treg imbalance in an OVA-induced allergic asthma mouse model through LAT-PLC-γ1 interaction
Fulltext Access 7 Pages 2017
Curcumin reduces the risk of chronic kidney damage in mice with nonalcoholic steatohepatitis by modulating endoplasmic reticulum stress and MAPK signaling
Fulltext Access 7 Pages 2017
Naturally occurring xanthone and benzophenone derivatives exert significant anti-proliferative and proapoptotic effects in vitro on synovial fibroblasts and macrophages from rheumatoid arthritis patients
Fulltext Access 7 Pages 2017
Anti-inflammatory effect of epigallocatechin gallate in a mouse model of ovalbumin-induced allergic rhinitis
Fulltext Access 7 Pages 2017
Colorectal tumors are enriched with regulatory plasmablasts with capacity in suppressing T cell inflammation
Fulltext Access 7 Pages 2017
Behavioral sensitization to methamphetamine induces specific interneuronal mRNA pathology across the prelimbic and orbitofrontal cortices
Fulltext Access 7 Pages 2017
The folic acid combined with 17-β estradiol produces antidepressant-like actions in ovariectomized rats forced to swim
Fulltext Access 7 Pages 2017
Tail vein injection of mmLDL upregulates mouse mesenteric artery ETB receptors via activation of the ERK1/2 pathway
Fulltext Access 7 Pages 2017
Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation
Fulltext Access 7 Pages 2017
Teneligliptin, a dipeptidyl peptidase-4 inhibitor, attenuated pro-inflammatory phenotype of perivascular adipose tissue and inhibited atherogenesis in normoglycemic apolipoprotein-E-deficient mice
Fulltext Access 7 Pages 2017
FTY720 promotes pulmonary fibrosis when administered during the remodelling phase following a bleomycin-induced lung injury
Fulltext Access 7 Pages 2017
Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils
Fulltext Access 7 Pages 2017
IL-4R suppresses airway inflammation in bronchial asthma by inhibiting the IL-4/STAT6 pathway
Fulltext Access 7 Pages 2017
Adiponectin down-regulates CREB and inhibits proliferation of A549 lung cancer cells
Fulltext Access 7 Pages 2017
Lipopolysaccharide (LPS) induced pulmonary neutrophil recruitment and platelet activation is mediated via the P2Y1 and P2Y14 receptors in mice
Fulltext Access 7 Pages 2017
Clinical outcome associated with the use of different inhalation method with and without humidification in asthmatic mechanically ventilated patients
Fulltext Access 7 Pages 2017
In vitro activity of alpha-viniferin isolated from the roots of Carex humilis against Mycobacterium tuberculosis
Fulltext Access 7 Pages 2017
SLC6A1 gene involvement in susceptibility to attention-deficit/hyperactivity disorder: A case-control study and gene-environment interaction
Fulltext Access 7 Pages 2017
Clarithromycin inhibits TNF-α-induced MUC5AC mucin gene expression via the MKP-1-p38MAPK-dependent pathway
Fulltext Access 7 Pages 2017
Cotinine improves visual recognition memory and decreases cortical Tau phosphorylation in the Tg6799 mice
Fulltext Access 7 Pages 2017
Does genetic BDNF deficiency in rats interact with neurotransmitter control of prepulse inhibition? Implications for schizophrenia
Fulltext Access 7 Pages 2017
Cav1.2, but not Cav1.3, L-type calcium channel subtype mediates nicotine-induced conditioned place preference in miceo
Fulltext Access 7 Pages 2017
Altered functional connectivity in default mode network in Internet gaming disorder: Influence of childhood ADHD
Fulltext Access 7 Pages 2017
Pharmacogenetics of antidepressant response: A polygenic approach
Fulltext Access 7 Pages 2017
Affective and cognitive correlates of PTSD: Electrocortical processing of threat and perseverative errors on the WCST in combat-related PTSD
Fulltext Access 7 Pages 2017
Epigenetic and genetic variants in the HTR1B gene and clinical improvement in children and adolescents treated with fluoxetine
Fulltext Access 7 Pages 2017
Quantifying dimensional severity of obsessive-compulsive disorder for neurobiological research
Fulltext Access 7 Pages 2017
Disrupted implicit motor sequence learning in schizophrenia and bipolar disorder revealed with ambidextrous Serial Reaction Time Task
Fulltext Access 7 Pages 2017
Clinical outcomes of switching from insulin glargine to NPH insulin in indigent patients at a charitable pharmacy: The Charitable Insulin NPH: Care for the Indigent study
Fulltext Access 7 Pages 2017
Impact of a telephonic outreach program on medication adherence in Medicare Advantage Prescription Drug (MAPD) plan beneficiaries
Fulltext Access 7 Pages 2017
Evaluation of antibacterial potential and toxicity of plant volatile compounds using new broth microdilution volatilization method and modified MTT assay
Fulltext Access 7 Pages 2017
C5a/C5aR pathway accelerates renal ischemia-reperfusion injury by downregulating PGRN expression
Fulltext Access 7 Pages 2017
Stereoselective pharmacokinetics of 25-methoxyl-dammarane-3β,12β,20-triol and its active demethyl-metabolite epimers in rats after oral and intravenous administration
Fulltext Access 7 Pages 2017
Isolation of novel stilbenoids from the roots of Cyrtopodium paniculatum (Orchidaceae)
Fulltext Access 7 Pages 2017
New phenylpropanoid-substituted flavan-3-ols and flavonols from the leaves of Uncaria rhynchophylla
Fulltext Access 7 Pages 2017
Triterpenoids and lignans from the fruit of Schisandra sphenanthera
Fulltext Access 7 Pages 2017
New terpenoids from Resina Commiphora
Fulltext Access 7 Pages 2017
Anti-inflammatory lignanamides and monoindoles from Alocasia macrorrhiza
Fulltext Access 7 Pages 2017
New seco-limonoids from Cipadessa baccifera: Isolation, structure determination, synthesis and their antiproliferative activities
Fulltext Access 7 Pages 2017
Monomeric and dimeric ent-kauranoid-type diterpenoids from rabdosia japonica and their cytotoxicity and anti-HBV activities
Fulltext Access 7 Pages 2017
Flavan-3-ols and proanthocyanidins from Limonium brasiliense inhibit the adhesion of Porphyromonas gingivalis to epithelial host cells by interaction with gingipains
Fulltext Access 7 Pages 2017
Eight new γ-lactam alkaloids from the roots of the Hemerocallis minor Mill
Fulltext Access 7 Pages 2017
Sesquiterpenoids from the cultured mycelia of Ganoderma capense
Fulltext Access 7 Pages 2017
CXCR5+ CD8+ T cells could induce the death of tumor cells in HBV-related hepatocellular carcinoma
Fulltext Access 7 Pages 2017
Dual high-resolution inhibition profiling and HPLC-HRMS-SPE-NMR analysis for identification of α-glucosidase and radical scavenging inhibitors in Solanum americanum Mill.
Fulltext Access 7 Pages 2017
C21 steroidal glycosides and oligosaccharides from the root bark of Periploca sepium
Fulltext Access 7 Pages 2017
Cyclooxygenase inhibitory compounds from Gymnosporia heterophylla aerial parts
Fulltext Access 7 Pages 2017
Antibacterial secondary metabolites from an endophytic fungus, Fusarium solani JK10
Fulltext Access 7 Pages 2017
Highly oxygenated lanostane-type triterpenoids and their bioactivity from the fruiting body of Ganoderma gibbosum
Fulltext Access 7 Pages 2017
Seven new lignan glycosides from the branches of Alangium kurzii Craib var. laxifolium
Fulltext Access 7 Pages 2017
Phenolic acids from Balanophora involucrata and their bioactivities
Fulltext Access 7 Pages 2017
New depsides from the roots of Salvia miltiorrhiza and their radical-scavenging capacity and protective effects against H2O2-induced H9c2 cells
Fulltext Access 7 Pages 2017
Lignans from the root of Wikstroemia indica and their cytotoxic activity against PANC-1 human pancreatic cancer cells
Fulltext Access 7 Pages 2017
Lignanamides with potent antihyperlipidemic activities from the root bark of Lycium chinense
Fulltext Access 7 Pages 2017
New alkenylated tetrahydropyran derivatives from the marine sediment-derived fungus Westerdykella dispersa and their bioactivities
Fulltext Access 7 Pages 2017
Exposure to particulate matter 2.5 (PM2.5) induced macrophage-dependent inflammation, characterized by increased Th1/Th17 cytokine secretion and cytotoxicity
Fulltext Access 7 Pages 2017
LL-37-induced human mast cell activation through G protein-coupled receptor MrgX2
Fulltext Access 7 Pages 2017
Inhibitory effects of 2-oxo-2H-chromen-4-yl 4-methylbenzenesulfonate on allergic inflammatory responses in rat basophilic leukemia cells
Fulltext Access 7 Pages 2017
Cholecystokinin protects mouse liver against ischemia and reperfusion injury
Fulltext Access 7 Pages 2017
Activated Akt/mTOR-autophagy in local T cells of oral lichen planus
Fulltext Access 7 Pages 2017
Βeta-eudesmol reduces stem cell factor-induced mast cell migration
Fulltext Access 7 Pages 2017
Kaempferol slows intervertebral disc degeneration by modifying LPS-induced osteogenesis/adipogenesis imbalance and inflammation response in BMSCs
Fulltext Access 7 Pages 2017
The NLRP3 inflammasome is a potential target of ozone therapy aiming to ease chronic renal inflammation in chronic kidney disease
Fulltext Access 7 Pages 2017
The effect of trimethylamine N-oxide on Helicobacter pylori-induced changes of immunoinflammatory genes expression in gastric epithelial cells
Fulltext Access 7 Pages 2017
B cells present skewed profile and lose the function of supporting T cell inflammation after Roux-en-Y gastric bypass
Fulltext Access 7 Pages 2017
Escherichia coli maltose-binding protein (MBP) activates mouse Th1 through TLR2-mediated MyD88-dependent pathway and TLR4-mediated TRIF-dependent pathway
Fulltext Access 7 Pages 2017
Influence of the number and interval of treatment cycles on cytokine-induced killer cells and their adjuvant therapeutic effects in advanced non-small-cell lung cancer (NSCLC)
Fulltext Access 7 Pages 2017
Cryptotanshinone protects against IL-1β-induced inflammation in human osteoarthritis chondrocytes and ameliorates the progression of osteoarthritis in mice
Fulltext Access 7 Pages 2017
Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii
Fulltext Access 7 Pages 2017
A comparative analysis between proteasome and immunoproteasome inhibition in cellular and humoral alloimmunity
Fulltext Access 7 Pages 2017
Effective tumor immunity to melanoma mediated by B16F10 cancer stem cell vaccine
Fulltext Access 7 Pages 2017
The effect of Astragaloside IV on ethanol-induced gastric mucosal injury in rats: Involvement of inflammation
Fulltext Access 7 Pages 2017
Alpha-Mangostin suppresses interleukin-1β-induced apoptosis in rat chondrocytes by inhibiting the NF-κB signaling pathway and delays the progression of osteoarthritis in a rat model
Fulltext Access 7 Pages 2017
Advanced glycation end products induced IL-6 and VEGF-A production and apoptosis in osteocyte-like MLO-Y4 cells by activating RAGE and ERK1/2, P38 and STAT3 signalling pathways
Fulltext Access 7 Pages 2017
Focus on the therapeutic efficacy of 3BNC117 against HIV-1: In vitro studies, in vivo studies, clinical trials and challenges
Fulltext Access 7 Pages 2017
Propofol inhibits NF-κB activation to ameliorate airway inflammation in ovalbumin (OVA)-induced allergic asthma mice
Fulltext Access 7 Pages 2017
CCR10 activation stimulates the invasion and migration of breast cancer cells through the ERK1/2/MMP-7 signaling pathway
Fulltext Access 7 Pages 2017
Immunomodulatory effects of M2000 (β-D-Mannuronic acid) on TNF-α, IL-17 and FOXP3 gene expression in patients with inflammatory bowel disease
Fulltext Access 7 Pages 2017
MiR-let-7a regulates anti-citrullinated protein antibody-induced macrophage activation and correlates with the development of experimental rheumatoid arthritis
Fulltext Access 7 Pages 2017
Immunogenicity and protective efficacy of multistage vaccine candidates (Mtb8.4-HspX and HspX-Mtb8.4) against Mycobacterium tuberculosis infection in mice
Fulltext Access 7 Pages 2017
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