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Pharmacology Research Articles

The spinal nitric oxide involved in the inhibitory effect of midazolam on morphine-induced analgesia tolerance
Fulltext Access 11 Pages 2005
Role of NMDA, nicotinic, and GABA receptors in the steady-state visual-evoked potential in rats
Fulltext Access 11 Pages 2005
Interaction of cocaine and dopamine transporter inhibitors on behavior and neurochemistry in monkeys
Fulltext Access 11 Pages 2005
Clonidine pre-treatment fails to block acute smoking-induced EEG arousal/mood in cigarette smokers
Fulltext Access 11 Pages 2005
The role of endocannabinoid transmission in cocaine addiction
Fulltext Access 11 Pages 2005
Activity density in the open field: a measure for differentiating the effect of psychostimulants
Fulltext Access 11 Pages 2005
Scheduled access to ethanol results in motor impairment and tolerance in female C57BL/6J mice
Fulltext Access 11 Pages 2005
Stimulation of 5-HT1B receptors decreases cocaine- and sucrose-seeking behavior
Fulltext Access 11 Pages 2005
Learning the morphine conditioned cue preference: Cue configuration determines effects of lesions
Fulltext Access 11 Pages 2005
Cocaine's effects on the perception of socially significant vocalizations in baboons
Fulltext Access 11 Pages 2005
Ultra-low-dose naltrexone reduces the rewarding potency of oxycodone and relapse vulnerability in rats
Fulltext Access 11 Pages 2005
Effects of maternal separation on voluntary ethanol intake and brain peptide systems in female Wistar rats
Fulltext Access 11 Pages 2005
Behavioral and pharmacological characterization of a distal peripheral nerve injury in the rat
Fulltext Access 12 Pages 2005
Evidence for Pavlovian conditioning of cocaine-induced responses linked to emotional behavioral effects
Fulltext Access 12 Pages 2005
KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia
Fulltext Access 12 Pages 2005
Endocannabinoid system and stress and anxiety responses
Fulltext Access 12 Pages 2005
Acute and repeated intravenous cocaine-induced locomotor activity is altered as a function of sex and gonadectomy
Fulltext Access 12 Pages 2005
Plasma cocaine levels, metabolites, and locomotor activity after subcutaneous cocaine injection are stable across the postpartum period in rats
Fulltext Access 12 Pages 2005
Trigeminal P2X3 receptor expression differs from dorsal root ganglion and is modulated by deep tissue inflammation
Fulltext Access 12 Pages 2005
Activated PKA and PKC, but not CaMKIIα, are required for AMPA/Kainate-mediated pain behavior in the thermal stimulus model
Fulltext Access 12 Pages 2005
Comparative actions of the opioid analgesics morphine, methadone and codeine in rat models of peripheral and central neuropathic pain
Fulltext Access 12 Pages 2005
Reduction of pain-related fear in complex regional pain syndrome type I: The application of graded exposure in vivo
Fulltext Access 12 Pages 2005
Antidepressants attenuate both the enhanced ethanol intake and ethanol-induced anxiolytic effects in diazepam withdrawn rats
Fulltext Access 12 Pages 2005
Alcohol use disorders in EU countries and Norway: An overview of the epidemiology
Fulltext Access 12 Pages 2005
Ammonia toxicity under hyponatremic conditions in astrocytes: De novo synthesis of amino acids for the osmoregulatory response
Fulltext Access 12 Pages 2005
An update on the role of brain glutamine synthesis and its relation to cell-specific energy metabolism in the hyperammonemic brain: Further studies using NMR spectroscopy
Fulltext Access 12 Pages 2005
Low-dose cholinesterase inhibitors do not induce delayed effects on cerebral blood flow and metabolism
Fulltext Access 12 Pages 2005
mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain
Fulltext Access 12 Pages 2005
Characteristics of rectal perception are altered in irritable bowel syndrome
Fulltext Access 12 Pages 2005
CD40-CD40L interactions promote neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism
Fulltext Access 12 Pages 2005
Neurotrophins protect against cytosine arabinoside-induced apoptosis of immature rat cerebellar neurons
Fulltext Access 12 Pages 2005
Differences in the in vivo dynamics of neurotransmitter release and serotonin uptake after acute para-methoxyamphetamine and 3,4-methylenedioxymethamphetamine revealed by chronoamperometry
Fulltext Access 12 Pages 2005
Pentylenetetrazol-induced seizures affect the levels of prolyl oligopeptidase, thimet oligopeptidase and glial proteins in rat brain regions, and attenuation by MK-801 pretreatment
Fulltext Access 12 Pages 2005
Cyclosporine a induces growth arrest or programmed cell death of human glioma cells
Fulltext Access 12 Pages 2005
Interaction between adenosine A2B-receptors and α2-adrenoceptors on the modulation of noradrenaline release in the rat vas deferens: Possible involvement of a group 2 adenylyl cyclase isoform
Fulltext Access 12 Pages 2005
Neuronal and glial cell lines as model systems for studying P2Y receptor pharmacology
Fulltext Access 12 Pages 2005
Disease-related regressive alterations of forebrain cholinergic system in SOD1 mutant transgenic mice
Fulltext Access 12 Pages 2005
Selective 5-HT1B receptor agonist reduces serotonin synthesis following acute, and not chronic, drug administration: results of an autoradiographic study
Fulltext Access 12 Pages 2005
IL-6 expression induced by adenosine A2b receptor stimulation in U373 MG cells depends on p38 mitogen activated kinase and protein kinase C
Fulltext Access 12 Pages 2005
In vitro characterization of novel NR2B selective NMDA receptor antagonists
Fulltext Access 12 Pages 2005
Cognitive consequences of cannabis use: Comparison with abuse of stimulants and heroin with regard to attention, memory and executive functions
Fulltext Access 12 Pages 2005
Keynote review: The adipocyte as a drug discovery target
Fulltext Access 12 Pages 2005
Keynote review: Recent advances in biomarkers for cancer diagnosis and treatment
Fulltext Access 12 Pages 2005
Anxiolytic-like effect of milnacipran in the four-plate test in mice: Mechanism of action
Fulltext Access 12 Pages 2005
Effects of 3,4-methylenedioxymethamphetamine and related amphetamines on autonomic and behavioral thermoregulation
Fulltext Access 12 Pages 2005
Involvement of 5-HT2 receptors in the antinociceptive effect of Uncaria tomentosa
Fulltext Access 12 Pages 2005
Validation of the tremulous jaw movement model for assessment of the motor effects of typical and atypical antipychotics: effects of pimozide (Orap) in rats
Fulltext Access 12 Pages 2005
The interactive effects of nicotinic and muscarinic cholinergic receptor inhibition on fear conditioning in young and aged C57BL/6 mice
Fulltext Access 12 Pages 2005
Endocannabinoid system and alcohol addiction: Pharmacological studies
Fulltext Access 12 Pages 2005
Thiamine, pyridoxine, cyanocobalamin and their combination inhibit thermal, but not mechanical hyperalgesia in rats with primary sensory neuron injury
Fulltext Access 12 Pages 2005
Place actuelle des endoprothèses coronaires dans le traitement de la cardiopathie ischémique
Fulltext Access 12 Pages 2005
Pharmacokinetic Study of Methotrexate Following Intra-Articular Injection of Methotrexate Loaded Poly(L-Lactic Acid) Microspheres in Rabbits
Fulltext Access 12 Pages 2005
Versatile Peptide Dendrimers for Nucleic Acid Delivery
Fulltext Access 12 Pages 2005
Pharmacokinetics and Metabolism of Metoprolol and Propranolol in the Female DA and Female Wistar Rat: The Female DA Rat Is Not Always an Animal Model for Poor Metabolizers of CYP2D6
Fulltext Access 12 Pages 2005
Peroxide-Mediated Desulfurization of Phosphorothioate Oligonucleotides and Its Prevention
Fulltext Access 12 Pages 2005
Dendrisomes: Vesicular Structures Derived from a Cationic Lipidic Dendron
Fulltext Access 12 Pages 2005
Complexation of celecoxib with β‐cyclodextrin: Characterization of the interaction in solution and in solid state
Fulltext Access 12 Pages 2005
A factor analysis for complex systems containing nimesulide
Fulltext Access 12 Pages 2005
Carrier mediated transport of chlorpheniramine and chlorcyclizine across bovine olfactory mucosa: Implications on nose‐to‐brain transport
Fulltext Access 12 Pages 2005
Reductase‐mediated metabolism of motexafin gadolinium (Xcytrin®) in rat and human liver subcellular fractions and purified enzyme preparations
Fulltext Access 12 Pages 2005
Effects of electrophoresis and electroosmosis during alternating current iontophoresis across human epidermal membrane
Fulltext Access 12 Pages 2005
Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water‐soluble drug
Fulltext Access 12 Pages 2005
Les médicaments radiopharmaceutiques
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Tissue Distribution of Basic Drugs: Accounting for Enantiomeric, Compound and Regional Differences Amongst β-Blocking Drugs in Rat
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Place de la chimiothérapie de première ligne dans le cancer de l'ovaire
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Mapping the Dose-Effect Relationship of Orbofiban from Sparse Data with an Artificial Neural Network
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Characterization of Physico-Mechanical Properties of Indomethacin and Polymers to Assess their Suitability for Hot-Melt Extrusion Processs as a Means to Manufacture Solid Dispersion/Solution*
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Evaluation of pig esophageal mucosa as a permeability barrier model for buccal tissue
Fulltext Access 12 Pages 2005
Significant differences in the disposition of cyclic prodrugs of opioid peptides in rats and guinea pigs following IV administration
Fulltext Access 12 Pages 2005
Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: Association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium
Fulltext Access 12 Pages 2005
pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs: Kinetic analysis of quinidine efflux in situ
Fulltext Access 12 Pages 2005
The Metabolic Profile of Azimilide in Man: In Vivo and in Vitro Evaluations
Fulltext Access 12 Pages 2005
Particle Size and Density in Spray Drying-Effects of Carbohydrate Properties
Fulltext Access 12 Pages 2005
A Study of Sulfamerazine Single Crystals Using Atomic Force Microscopy, Transmission Light Microscopy, and Raman Spectroscopy
Fulltext Access 12 Pages 2005
Effect of Amino Acids on the Dispersion of Disodium Cromoglycate Powders
Fulltext Access 12 Pages 2005
Repeated exposure to Δ9-tetrahydrocannabinol alters heroin-induced locomotor sensitisation and Fos-immunoreactivity
Fulltext Access 12 Pages 2005
Evidence for a long-term influence on morphie tolerance after previous morphine exposure: role of neuronal glucocorticoid receptors
Fulltext Access 12 Pages 2005
Altered primary afferent anatomy and reduced thermal sensitivity in mice lacking galectin-1
Fulltext Access 12 Pages 2005
Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors
Fulltext Access 12 Pages 2005
Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia
Fulltext Access 12 Pages 2005
Persistent idiopathic facial pain exists independent of somatosensory input from the painful region: findings from quantitative sensory functions and somatotopy of the primary somatosensory cortex
Fulltext Access 12 Pages 2005
A cannabinoid agonist, WIN 55,212-2, reduces neuropathic nociception induced by paclitaxel in rats
Fulltext Access 12 Pages 2005
The significant other version of the Pain Catastrophizing Scale (PCS-S): Preliminary validation
Fulltext Access 12 Pages 2005
Effects of cinnarizine, a calcium antagonist that produces human parkinsonism, in parkin knock out mice
Fulltext Access 12 Pages 2005
Design of antagonists for NMDA and AMPA receptors
Fulltext Access 12 Pages 2005
Peripherally acting NMDA receptor/glycineB site receptor antagonists inhibit morphine tolerance
Fulltext Access 12 Pages 2005
Non-steroidal anti-inflammatory drugs have anti-amyloidogenic effects for Alzheimer's β-amyloid fibrils in vitro
Fulltext Access 12 Pages 2005
Down-regulation of the glial glutamate transporter GLT-1 in rat hippocampus and striatum and its modulation by a group III metabotropic glutamate receptor antagonist following transient global forebrain ischemia
Fulltext Access 12 Pages 2005
Folate Receptor-Mediated Drug Targeting: From Therapeutics to Diagnostics
Fulltext Access 12 Pages 2005
Glycinergic inhibition in thalamus revealed by synaptic receptor blockade
Fulltext Access 12 Pages 2005
Water Adsorption Kinetics and Contact Angles of Pharmaceutical Powders
Fulltext Access 12 Pages 2005
Partially Crystalline Systems in Lyophilization: II. Withstanding Collapse at High Primary Drying Temperatures and Impact on Protein Activity Recovery
Fulltext Access 12 Pages 2005
Pharmacokinetic Effects of 4C9, An Anti-FcRn Antibody, in Rats: Implications for the Use of FcRn Inhibitors for the Treatment of Humoral Autoimmune and Alloimmune Conditions
Fulltext Access 12 Pages 2005
Single Crystal and Powder Diffraction Characterization of Three Polymorphic Forms of Acitretin
Fulltext Access 12 Pages 2005
The Effect of Water to Ethanol Feed Ratio on Physical Properties and Aerosolization Behavior of Spray Dried Cromolyn Sodium Particles
Fulltext Access 12 Pages 2005
Microdialysis evaluation of the brain distribution of stavudine following intranasal and intravenous administration to rats
Fulltext Access 12 Pages 2005
Surface roughness contribution to the adhesion force distribution of salmeterol xinafoate on lactose carriers by atomic force microscopy
Fulltext Access 12 Pages 2005
Effect of the covalent modification of horseradish peroxidase with poly(ethylene glycol) on the activity and stability upon encapsulation in polyester microspheres
Fulltext Access 12 Pages 2005
Intracellular delivery of doxorubicin with RGD-modified sterically stabilized liposomes for an improved antitumor efficacy: In vitro and in vivo
Fulltext Access 12 Pages 2005
Lipid Binding Region (2303-2332) is Involved in Aggregation of Recombinant Human FVIII (rFVIII)*
Fulltext Access 12 Pages 2005
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