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Daneshyari Pharmacology Journas Latest Articles

Pharmacology Research Articles

An aqueous extract of the popular Chinese nutraceutical Kwei Ling Ko (Tortoise shell-Rhizome Jelly) activates the PPARγ pathway and down-regulates the NFκB activity
Fulltext Access 12 Pages 2005
Comparison of the efficacy of ciclesonide 160 μg QDand budesonide 200 μg BID in adults with persistent asthma: A phase III, randomized, double-dummy, open-label study
Fulltext Access 12 Pages 2005
Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew
Fulltext Access 12 Pages 2005
Herb and supplement use in the US adult population
Fulltext Access 12 Pages 2005
The efficacy and safety of inhaled fluticasone propionate/salmeterol and ipratropium/albuterol for the treatment of chronic obstructive pulmonary disease: An eight-week, multicenter, randomized, double-blind, double-dummy, parallel-group study
Fulltext Access 12 Pages 2005
Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576
Fulltext Access 12 Pages 2005
Clinic blood pressure responses to two amlodipine salt formulations, adipate and besylate, in adult Korean patients with mild to moderate hypertension: A multicenter, randomized, double-blind, parallel-group, 8-week comparison
Fulltext Access 12 Pages 2005
Phasic cardiovascular responses to mevinphos are mediated through differential activation of cGMP/PKG cascade and peroxynitrite via nitric oxide generated in the rat rostral ventrolateral medulla by NOS I and II isoforms
Fulltext Access 12 Pages 2005
Endocannabinoid release from midbrain dopamine neurons: a potential substrate for cannabinoid receptor antagonist treatment of addiction
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Neuronal Kir3.1/Kir3.2a channels coupled to serotonin 1A and muscarinic m2 receptors are differentially modulated by the 'short' RGS3 isoform
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Differential expression of P2X receptors on neurons from different parasympathetic ganglia
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Efficacy and safety of biphasic insulin aspart 30 combined with pioglitazone in type 2 diabetes poorly controlled on glibenclamide (glyburide) monotherapy or combination therapy: An 18-week, randomized, open-label study
Fulltext Access 12 Pages 2005
Safety and effectiveness of topiramate for the management of painful diabetic peripheral neuropathy in an open-label extension study
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Role of α7-nicotinic acetylcholine receptors in tetanic stimulation-induced γ oscillations in rat hippocampal slices
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Incidence of infection during efalizumab therapy for psoriasis: Analysis of the clinical trial experience
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Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats
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Effect of acute and chronic psychostimulant drugs on redox status, AP-1 activation and pro-enkephalin mRNA in the human astrocyte-like U373 MG cells
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Iron protects astrocytes from 6-hydroxydopamine toxicity
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Antimuscarinic agents: Implications and concerns in themanagement of overactive bladder in the elderly
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Effectiveness and tolerability of the buprenorphinetransdermal system in patients with moderate to severe chronic pain: A multicenter, open-label, uncontrolled, prospective, observational clinical study
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Nizatidine for the treatment of pediatric gastroesophageal reflux symptoms: An open-label, multiple-dose, randomized, multicenter clinical trial in 210 children
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Quantifying the use of the statin antilipemic drugs: Comparisons and contrasts between Nova Scotia, Canada, and Queensland, Australia
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Analgesic efficacy and tolerability of oxycodone 5 mg/ibuprofen400 mg compared with those of oxycodone 5 mg/acetaminophen 325 mg and hydrocodone 7.5 mg/acetaminophen 500 mg in patients with moderate to severe postoperative pain: A randomized, double-blind
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Ncm-d-aspartate: A novel caged d-aspartate suitable for activation of glutamate transporters and N-methyl-d-aspartate (NMDA) receptors in brain tissue
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Patterns of care, outcomes, and direct health plan costs of antiepileptic therapy: a pharmacoeconomic analysis of the available carbamazepine formulations
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The substituted aspartate analogue l-β-threo-benzyl-aspartate preferentially inhibits the neuronal excitatory amino acid transporter EAAT3
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Topiramate monotherapy in epilepsy and migraineprevention
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Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain
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Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis
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FlexPen®: Addressing issues of confidence andconvenience in insulin delivery
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Prevalence and correlates of potentially inappropriate prescribing among ambulatory older patients in the year 2001: Comparison of three explicit criteria
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Group II and III mGluRs-mediated presynaptic inhibition of EPSCs recorded from hippocampal interneurons of CA1 stratum lacunosum moleculare
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Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats
Fulltext Access 12 Pages 2005
Effects of switching from olanzapine to risperidone on the prevalence of the metabolic syndrome in overweight or obese patients with schizophrenia or schizoaffective disorder: Analysis of a multicenter, rater-blinded, open-label study
Fulltext Access 12 Pages 2005
Combination oxycodone 5 mg/ibuprofen 400 mg for thetreatment of pain after abdominal or pelvic surgery in women: A randomized, double-blind, placebo- and active-controlled parallel-group study
Fulltext Access 13 Pages 2005
Triple therapy with glimepiride in patients with type 2diabetes mellitus inadequately controlled by metformin and a thiazolidinedione: Results of a 30-week, randomized, double-blind, placebo-controlled, parallel-group study
Fulltext Access 13 Pages 2005
Pramlintide in the treatment of type 1 and type 2 diabetes mellitus
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Equipotent doses of transdermal fentanyl and transdermal buprenorphine in patients with cancer and noncancer pain: Results of a retrospective cohort study
Fulltext Access 13 Pages 2005
Evaluation of the cost-effectiveness of Sirolimus versus cyclosporin for immunosuppression after renal transplantation in the United Kingdom
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Efficacy and safety profile of fenofibrate-coated microgranules 130 mg, with and without food, in patients with hypertriglyceridemia and the metabolic syndrome: An 8-week, randomized, double-blind, placebo-controlled study
Fulltext Access 13 Pages 2005
Enhanced thermal avoidance in mice lacking the ATP receptor P2X3
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CYP2K6 from zebrafish (Danio rerio): Cloning, mapping, developmental/tissue expression, and aflatoxin B1 activation by baculovirus expressed enzyme
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Apoptosis and biochemical biomarkers of stress in spiders from industrially polluted areas exposed to high temperature and dimethoate
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Pain-related emotions modulate experimental pain perception and autonomic responses
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Role of NK-1 neurotransmission in opioid-induced hyperalgesia
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Sensory and motor effects of experimental muscle pain in patients with lateral epicondylalgia and controls with delayed onset muscle soreness
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Primary afferent second messenger cascades interact with specific integrin subunits in producing inflammatory hyperalgesia
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Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation
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Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse
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A systematic review of trial methodology, using the placebo groups of randomized controlled trials in paediatric postoperative pain
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Practical approaches to insulin therapy for type 2 diabetes mellitus with premixed insulin analogues
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Microarray analysis of gene expression following the formalin test in the infant rat
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α-Conotoxins as selective probes for nicotinic acetylcholine receptor subclasses
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Treatment of cognitive dysfunction in schizophrenia
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Testim® 1% testosterone gel for the treatment of male hypogonadism
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The role of luteinizing hormone-releasing hormone therapy in locally advanced prostate cancer and biochemical failure: considerations for optimal use
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New class of linoleic acid metabolites biosynthesized by corn and rice lipoxygenases: Suppression of proinflammatory mediator expression via attenuation of MAPK- and Akt-, but not PPARγ-, dependent pathways in stimulated macrophages
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Clinical applications of exhaled nitric oxide for the diagnosis and management of asthma: A consensus report
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An open-label, noncomparative study of miglustat in type I Gaucher disease: Efficacy and tolerability over 24 months of treatment
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Coupling of human nicotinic acetylcholine receptors α7 to calcium channels in GH3 cells
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Establishment of robust functional assays for the characterization of neuropeptide Y (NPY) receptors: identification of 3-(5-benzoyl-thiazol-2-ylamino)-benzonitrile as selective NPY type 5 receptor antagonist
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Long-term potentiation persists in an occult state following mGluR-dependent depotentiation
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Peripheral, but not central effects of cannabidiol derivatives: Mediation by CB1 and unidentified receptors
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β-Carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway
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Interaction of corticosterone and nicotine in regulation of prepulse inhibition in mice
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Virus-encoded chemokine receptors - putative novel antiviral drug targets
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Antiabsence effects of carbenoxolone in two genetic animal models of absence epilepsy (WAG/Rij rats and lh/lh mice)
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Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing
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Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus
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The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors
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Effects of a novel glutamate transporter blocker, (2S, 3S)-3-{3-[4-(trifluoromethyl)benzoylamino]benzyloxy}aspartate (TFB-TBOA), on activities of hippocampal neurons
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Transmembrane domains 1 and 3 of the glycine transporter GLYT1 contain structural determinants of N[3-(4′-fluorophenyl)-3-(4′-phenylphenoxy)-propyl]sarcosine specificity
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Effect of Milling and Compression on the Solid-State Maillard Reaction
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Understanding the Polymorphic Behavior of Sibenadet Hydrochloride through Detailed Studies Integrating Structural and Dynamical Assessment
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Sulfoalkyl Ether-Alkyl Ether Cyclodextrin Derivatives, their Synthesis, NMR Characterization, and Binding of 6α-Methylprednisolone
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Comparison of statistical analysis and Bayesian networks in the evaluation of dissolution performance of BCS Class II model drugs
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Solution behavior of a novel type 1 interferon, interferon-τ
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Reversible Self-Association Increases the Viscosity of a Concentrated Monoclonal Antibody in Aqueous Solution
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Effect Of the Variation in the Ambient Moisture on the Compaction Behavior of Powder Undergoing Roller-Compaction And On The Characteristics Of Tablets Produced From The Post-Milled Granules
Fulltext Access 13 Pages 2005
Influence of Ambient Moisture on the Compaction Behavior of Microcrystalline Cellulose Powder Undergoing Uni-Axial Compression and Roller-Compaction: A Comparative Study Using Near-Infrared Spectroscopy
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Amphiphilic pyridinium salts block TNFα/NFκB signaling and constitutive hypersecretion of interleukin-8 (IL-8) from cystic fibrosis lung epithelial cells
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Eukaryotic arylamine N-acetyltransferase
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Dicoumarol relieves serum withdrawal-induced G0/1 blockade in HL-60 cells through a superoxide-dependent mechanism
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Quercetin, but not rutin and quercitrin, prevention of H2O2-induced apoptosis via anti-oxidant activity and heme oxygenase 1 gene expression in macrophages
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Chrysin induces G1 phase cell cycle arrest in C6 glioma cells through inducing p21Waf1/Cip1 expression: Involvement of p38 mitogen-activated protein kinase
Fulltext Access 13 Pages 2005
Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells
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Tangutorine induces p21 expression and abnormal mitosis in human colon cancer HT-29 cells
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Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway
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SCF-Engineered Powders for Delivery of Budesonide from Passive DPI Devices
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HDAC inhibition prevents NF-κB activation by suppressing proteasome activity: Down-regulation of proteasome subunit expression stabilizes IκBα
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Changes in spectrin organisation in leukaemic and lymphoid cells upon chemotherapy
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Redox regulation: A new challenge for pharmacology
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Kinetics of tienilic acid bioactivation and functional generation of drug-protein adducts in intact rat hepatocytes
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Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors
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Extracts and molecules from medicinal plants against herpes simplex viruses
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Inhibition of CCR5-mediated infection by diverse R5 and R5X4 HIV and SIV isolates using novel small molecule inhibitors of CCR5: Effects of viral diversity, target cell and receptor density
Fulltext Access 13 Pages 2005
Bacopa monniera, a reputed nootropic plant: an overview
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Binding and functional properties of the novel somatostatin analogue KE 108 at native mouse somatostatin receptors
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Neurosteroid paradoxical enhancement of paired-pulse inhibition through paired-pulse facilitation of inhibitory circuits in dentate granule cells
Fulltext Access 13 Pages 2005
Dopamine inhibits cell growth and cell cycle by blocking ribonucleotide reductase
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