Magneto acoustic tomography with short pulsed magnetic field for in-vivo imaging of magnetic iron oxide nanoparticles

In magneto acoustic tomography a short pulsed magnetic field is applied to induce ultrasound in tissue labeled with magnetic nanoparticle through magneto motive force. Using ultrasound transducers placed around the object this ultrasound wave is measured. The reconstructed image from the ultrasound signal is a representation of the distribution of the magnetic nanoparticles in the tissue. This is shown in the present study with in-vivo experiments to detect and image the distribution of IONPs in live, nude mice with induced lymph node derived cancer of the prostate tumors over the hind limb.162