Extraction and chemical characterization of Angelica sinensis polysaccharides and its antioxidant activity

► ASP extraction procedure was optimized by an L9 (34) orthogonal array experimental design. ► CT perfusion imaging (CTP) analysis were done in CIR rabbits. ► ASP was found to decrease oxidative injury in CIR animals. ► Potent role of ASP in protection of brain oxidative injury in CIR animals.