Posterior capsular opacification and intraocular lens surface micro-roughness characteristics: An atomic force microscopy study

► AFM is a powerful technique for the topological characterization of IOLs. ► Acrylic hydrophobic IOLs have least surface roughness properties and PCO incidence. ► Acrylic hydrophobic IOLs may be ideally biocompatible for lowering PCO formation. ► Manufacturers need to optimize various steps involved in fabrication of IOLs.