Cellular immune response evaluation of cutaneous leishmaniasis patients cells stimulated with Leishmania (Viannia) braziliensis antigenic fractions before and after clinical cure

► Both fractions induced a specific immune response. ► The study included patients before, after treatment and those spontaneously healed. ► It was observed a transitory immunosuppression in the early phase of leishmaniasis. ► Patients after treatment or spontaneous healing had a type 1 predominant response. ► This investigation adds information on the search for relevant Leishmania antigens.