کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1192703 1492229 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A pilot study of direct infusion analysis by FT-ICR MS for rapid differentiation and authentication of traditional Chinese herbal medicines
ترجمه فارسی عنوان
یک مطالعه آزمایشی از تجزیه و تحلیل مستقیم انفوزیون توسط FT-ICR MS برای تمایز سریع و تأیید اعتبار داروهای گیاهی سنتی چینی
کلمات کلیدی
تجزیه و تحلیل تزریق مستقیم؛ طیف سنج جرم رزونانس سایکلوتون یون تبدیل فوریه؛ داروهای گیاهی سنتی چینی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی

The feasibility of direct infusion analysis in a Fourier-transform ion cyclotron resonance mass spectrometer (FT-ICR MS) for fast differentiation and authentication of traditional Chinese herbal medicines (TCHMs) was evaluated for the first time. The widely used Gardenia jasminoides Ellis and the clinical preparations Kudiezi injection were selected as model samples and analyzed by this method. With minimal or no sample pretreatment, 30 and 29 peaks which were corresponding to 43 and 40 chemical constituent respectively were rapidly detected and tentatively identified according to the accurate mass information and MS/MS data within only few minutes, including iridoids, phenolic acids, glucosides, flavonoids, nucleosides and sesquiterpene lactones. Our results demonstrated that direct infusion analysis in FT-ICR MS could provide a rapid, solvent saving and environmental friendly method for the differentiation and authentication of TCHMs, and it may be applicable to other plants.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Mass Spectrometry - Volume 403, 1 June 2016, Pages 62–67
نویسندگان
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