Ultra trace analysis of PAHs by designing simple injection of large amounts of analytes through the sample reconcentration on SPME fiber after magnetic solid phase extraction

• A simple solvent-less approach for the injection of large amounts of analytes to GC.
• Advantages of exhaustive extraction of MSPE and solvent-less injection of SPME.
• Improve the analysis sensitivity by coupling of MSPE and SPME.
• Earning high enhancement factors and low detection limits for determination of PAHs.

A simple solventless injection method was introduced based on the using of a solid-phase microextraction (SPME) fiber for injection of large amounts of the analytes extracted by the magnetic solid phase extraction (MSPE) procedure. The resulted extract from MSPE procedure was loaded on a G-coated SPME fiber, and then the fiber was injected into the gas chromatography (GC) injection port. This method combines the advantages of exhaustive extraction property of MSPE and the solvent-less injection of SPME to improve the sensitivity of the analysis. In addition, the analytes were re-concentrated prior to inject into the gas chromatography (GC) inlet because of the organic solvent removing from the remaining extract of MSPE technique. Injection of the large amounts of analytes was made possible by using the introduced procedure. Fourteen polycyclic aromatic hydrocarbons (PAHs) with different volatility were used as model compounds to investigate the method performance for volatile and semi-volatile compounds. The introduced method resulted in the higher enhancement factors (5097–59376), lower detection limits (0.29–3.3 pg mL−1), and higher sensitivity for the semi-volatile compounds compared with the conventional direct injection method.

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