کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1313867 | 1499344 | 2013 | 6 صفحه PDF | دانلود رایگان |
• Polyfluorinated 4-acetamidobiphenyls have been hydrodefluorinated with the Zn–NiCl2–2,2′-bipyridine–aq. DMF system.
• Polyfluorinated 4-acetamido- and 4-aminobiphenyls unsubstituted ortho to the NHR (R = Ac, H) group have been synthesized.
• The Skraup synthesis of polyfluorinated 6-phenylquinolines and 6,6′-biquinoline has been performed.
Polyfluorinated 4-acetamido- and 4,4′-bis(acetamido)biphenyl were reduced in the Zn–NiCl2–2,2′-bipyridine–aq. DMF system to give their for the first time synthesized less fluorinated analogs containing one or two unsubstituted position ortho to the acetamido group. By involving ortho-unsubstituted 4-acetamido- or 4-aminopolyfluorobiphenyls in the Skraup synthesis, new polyfluorinated 6-phenylquinolines and 6,6′-biquinoline were obtained.
Polyfluorinated 4-acetamido- and 4,4′-bis(acetamido)biphenyls are reduced in the Zn–NiCl2–2,2′-bipyridine–aq. DMF system to give their ortho-to-NHAc defluorinated analogs which are used as educts in the Skraup synthesis of polyfluorinated 6-phenylquinolines and 6,6′-biquinoline.Figure optionsDownload as PowerPoint slide
Journal: Journal of Fluorine Chemistry - Volume 156, December 2013, Pages 214–219