کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1328698 | 977619 | 2005 | 8 صفحه PDF | دانلود رایگان |
A new class of chiral ligands, e.g., (−)-9, based on the benzoxazine nucleus, has been designed and synthesized in three steps from the commercially available starting materials salicylamide and (−)-menthone. Application of (−)-9 in the palladium catalyzed-allylic substitution of 1,3-diphenyl-2-propenylacetate with dimethyl malonate gave enantioselectivities of up to 62%ee. Ees of 42% and 20% in asymmetric hydrosilylations and diethylzinc additions, respectively, were also obtained.
A new class of chiral ligands, based on the benzoxazin nucleus, has been designed and synthesized. Application of the chiral ligand in the palladium catalyzed-allylic substitution of 1,3-diphenyl-2-propenylacetate with dimethyl malonate gave enantioselectivities of up to 62%ee.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volume 690, Issue 8, 15 April 2005, Pages 2027–2034