Facile synthesis of nano-sized agarose based amino acid-Its pH-dependent protein-like behavior and interactions with bovine serum albumin

- Synthesis of nano-sized 6-aminoagarose succinate half-ester derivative (AAE).
- AAEs exhibited protein-like pH-responsive behavior.
- Zeta-potential measurements showed isoelectric points of AAEs at pH 4.
- AAEs exhibited pH-specific single strand and aggregate formation (ORD).
- AAEs exhibited pH-dependent associative interactions with bovine serum albumin.