کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1407078 | 1501888 | 2008 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Molecular geometry of antimalarial amodiaquine in different crystalline environments
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The crystal structures of antimalarial drug amodiaquine in the form of its free base and two salts, dihydrochloride monohydrate and tetrachlorocobaltate(II), were determined with X-ray single crystal diffractometry. Their conformations and intermolecular interactions are compared to those found in the crystalline amodiaquine dihydrochloride, postulated to contain hydroxyl anion, and in the powder amodiaquine dihydrate dihydrochloride. The molecular structures of the amodiaquine cation and its free base were optimized by the B3LYP calculations and compared to those observed in the crystalline state.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Structure - Volume 875, Issues 1â3, 17 March 2008, Pages 32-41
Journal: Journal of Molecular Structure - Volume 875, Issues 1â3, 17 March 2008, Pages 32-41
نویسندگان
Agata Semeniuk, Agnieszka Niedospial, Justyna Kalinowska-Tluscik, Wojciech Nitek, Barbara J. Oleksyn,