کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1408926 | 1501775 | 2013 | 6 صفحه PDF | دانلود رایگان |
Several novel 3-allyl-2-(substituted imino)-4-phenyl-3H-thiazole derivatives were synthesized by the reaction of allyl-thioureas and 2-bromoacetophenone. We also report the synthesis of bis-allyl-3H thiazoles using the reaction of various isothiocyanates and 1,3-phenylenediamine. The structures of all compounds were characterized by spectral and elemental analysis. Most of the synthesized compounds exhibited efficient antibacterial activities against Salmonella enterica, Micrococcus luteus, Bacillus subtilis and Pseudomonas aeruginosa.
► Synthesis of allyl-1,3-thiazoline and bis(1,3-thiazoline) have been studies.
► Antibacterial activity of 3H-thiazole and bis(3H-thiazole) derivatives were measured.
► Bis-structure indicated higher antibacterial activity compare to other compounds.
Journal: Journal of Molecular Structure - Volume 1039, 8 May 2013, Pages 113–118