کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2577542 1129949 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Activity of Corylus avellana seed oil in letrozole-induced polycystic ovary syndrome model in rats
ترجمه فارسی عنوان
عملکرد روغن دانه Corylus avellana در مدل سندرم تخمدان پلی کیستیک ناشی از لتروزول در موش صحرايی
کلمات کلیدی
Betulaceae؛ Corylus avellana؛ فیتواسترول؛ لتروزول؛ سندرم تخمدان پلی کیستیک؛ آنتی اکسیدان
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
چکیده انگلیسی

The aim of the present study was to assess the activity of the hazelnut oil in the treatment of polycystic ovary syndrome in rats. Serum follicle-stimulating hormone, luteinizing hormone, estradiol, progesterone, testosterone, serum lipid parameters, leptin and glucose levels were evaluated. Moreover, antioxidant activity was tested using superoxide dismutase, malondialdehyde, catalase, glutathione peroxidase levels. The phytosterol content of the oil was determined by HPLC. The plasma high density lipoprotein-cholesterol level was found to be significantly high and leptin and glucose concentrations were found to be significantly low in the treatment group. According to the phytochemical analysis, the main components of the oil were detected as α-tocopherol, γ-tocopherol, squalene, β-sitosterol, campesterol and stigmasterol. Corylus avellana oil was found to be effective in the treatment of polycystic ovary syndrome via regulating gonadotropins, steroids and serum lipid parameters and possesses antioxidant activity.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Brasileira de Farmacognosia - Volume 26, Issue 1, January–February 2016, Pages 83–88
نویسندگان
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