|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|34176||45008||2016||5 صفحه PDF||ندارد||دانلود کنید|
• Immobilisation of Clostridium tyrobutyricum to PVA gel.
• Remarkable stability of microorganism in repeated batches and continuous fermentations.
• Improvement of productivity of immobilised cell.
• Evaluation of entrapment and adsorption of biomass in/on PVA particles.
Clostridium tyrobutyricum was entrapped into lens-shaped polyvinyl alcohol particles (LentiKats®). Immobilised cells were propagated in series of repeated batches and reached average productivity of 1.74 g/L h and yield of 0.44 g/g during 31 repetitions with glucose as an initial substrate, which was 5 times higher productivity compared with a free cell system under the same conditions. Immobilised cells were successfully applied for more than 71 repeated batches and demonstrated remarkable process stability. Application of immobilised cells to a continuous system resulted in 5.8 times higher productivity compared with free cells, with 6.8 g/L of butyric acid and residual glucose of 5.8 g/L.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Journal: Process Biochemistry - Volume 51, Issue 6, June 2016, Pages 704–708