کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5135498 | 1493454 | 2016 | 4 صفحه PDF | دانلود رایگان |
- A high-throughput CE method for simultaneous determination of naphazoline and zinc.
- A single run can be performed every 55Â s (65Â hâ1).
- An analytical separation technique was proposed for the first time for simultaneous determination of naphazoline and zinc.
- Environmentally friendly method.
This paper reports for the first time, a method for simultaneous determination of naphazoline (NPZ) and zinc (Zn) using an analytical separation technique (capillary electrophoresis with capacitively coupled contactless conductivity detection -CE-C4D). A single run is possible every 55 s (sampling rate = 65 hâ1). The separation by CE-C4D was achieved on a fused silica capillary (50 cm length â 10 cm effective, 50 μm i.d.) with a background electrolyte (BGE) composed by 20 mmol Lâ1 of 2-(morpholin-4-yl)ethane-1-sulfonic acid (MES) and 20 mmol Lâ1 of histidine (HIS) (pH 6.0). Detection limits were estimated at 20 and 30 μmol Lâ1 and recovery values for spiked samples were 98 and 102% for NPZ and Zn, respectively. The developed procedure was compared to HPLC (NPZ) and FAAS (Zn) and no statistically significant differences were observed (95% confidence level).
Journal: Journal of Chromatography A - Volume 1472, 11 November 2016, Pages 134-137