کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5357671 | 1388221 | 2010 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
3â²-Hydroxy-4-methoxychalcone as a potential antibacterial coating on polymeric biomaterials
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Antimicrobial property of chalcone coated high density polyethylene (HDPE), low density polyethylene (LDPE), polypropylene (PP) and polyurethane (PU) against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa is reported here. The presence of chalcone on the surface was confirmed from fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Bacterial adhesion decreased considerably on all the coated surfaces. Bacterial adhesion was highest on PU surface (most hydrophobic) and lowest on HDPE (most hydrophilic) surface. Chalcone seems to damage the membrane of the bacteria as well as exhibit slimicidal activity. Reasonably good correlation was observed between the CFU (Colony Forming Units) ratio (it is defined as the ratio of CFU on coated surface to the chalcone uncoated surface) at the 24th hour against both hydrophobicity of the microorganism and roughness of the coated polymeric surfaces. Increasing roughness of the polymer and hydrophobicity of the microorganisms were positively and negatively correlated respectively with CFU ratio. Hence, the chalcone coated polymers can be used in the development of newer biomaterials.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Surface Science - Volume 256, Issue 20, 1 August 2010, Pages 6018-6024
Journal: Applied Surface Science - Volume 256, Issue 20, 1 August 2010, Pages 6018-6024
نویسندگان
P.M. Sivakumar, Geetha Iyer, Lavanya Natesan, Mukesh Doble,