Immobilization of biomolecules on biotinylated magnetic ferrite nanoparticles

Biocompatible ferrite (Fe3O4) nanoparticles whose surfaces are functionalized with biotin molecule show a high affinity for the Cy3-labeled streptavidin. The spectroscopic and magnetization results confirmed the strong interaction between biotin-anchored Fe3O4 particles and Cy3-labeled streptavidins. These biocompatible magnetic nanoparticles can be used as a basic protocol for various biological applications.